DE69522119T2 - Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen - Google Patents

Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen

Info

Publication number
DE69522119T2
DE69522119T2 DE69522119T DE69522119T DE69522119T2 DE 69522119 T2 DE69522119 T2 DE 69522119T2 DE 69522119 T DE69522119 T DE 69522119T DE 69522119 T DE69522119 T DE 69522119T DE 69522119 T2 DE69522119 T2 DE 69522119T2
Authority
DE
Germany
Prior art keywords
inhaler
inhalation
inhalation device
piston
air outlet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69522119T
Other languages
German (de)
English (en)
Other versions
DE69522119D1 (de
Inventor
Kjell Wetterlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE69522119D1 publication Critical patent/DE69522119D1/de
Publication of DE69522119T2 publication Critical patent/DE69522119T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A61M15/0088—Inhalation chambers with variable volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
DE69522119T 1994-12-21 1995-12-19 Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen Expired - Lifetime DE69522119T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9404439A SE9404439D0 (sv) 1994-12-21 1994-12-21 Inhalation device
PCT/SE1995/001539 WO1996019253A1 (en) 1994-12-21 1995-12-19 An inhalation device, a method of dispersing a pharmaceutically acitve substance and a method of administering a dose of a pharmaceutically active substance

Publications (2)

Publication Number Publication Date
DE69522119D1 DE69522119D1 (de) 2001-09-13
DE69522119T2 true DE69522119T2 (de) 2002-06-06

Family

ID=20396408

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69522119T Expired - Lifetime DE69522119T2 (de) 1994-12-21 1995-12-19 Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen

Country Status (25)

Country Link
US (1) US5983893A (cg-RX-API-DMAC10.html)
EP (1) EP0799067B1 (cg-RX-API-DMAC10.html)
JP (1) JP3712415B2 (cg-RX-API-DMAC10.html)
CN (1) CN1171056A (cg-RX-API-DMAC10.html)
AR (1) AR000522A1 (cg-RX-API-DMAC10.html)
AT (1) ATE203919T1 (cg-RX-API-DMAC10.html)
AU (1) AU698815B2 (cg-RX-API-DMAC10.html)
BR (1) BR9510210A (cg-RX-API-DMAC10.html)
CA (1) CA2207436A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ191397A3 (cg-RX-API-DMAC10.html)
DE (1) DE69522119T2 (cg-RX-API-DMAC10.html)
EE (1) EE9700132A (cg-RX-API-DMAC10.html)
FI (1) FI972697A0 (cg-RX-API-DMAC10.html)
HU (1) HUT77661A (cg-RX-API-DMAC10.html)
IL (1) IL116457A0 (cg-RX-API-DMAC10.html)
IS (2) IS4508A (cg-RX-API-DMAC10.html)
NO (1) NO972780D0 (cg-RX-API-DMAC10.html)
NZ (1) NZ298166A (cg-RX-API-DMAC10.html)
PL (1) PL179323B1 (cg-RX-API-DMAC10.html)
SE (1) SE9404439D0 (cg-RX-API-DMAC10.html)
SK (1) SK78297A3 (cg-RX-API-DMAC10.html)
TR (1) TR199501636A1 (cg-RX-API-DMAC10.html)
TW (1) TW286285B (cg-RX-API-DMAC10.html)
WO (1) WO1996019253A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA9510747B (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006007495A1 (de) * 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6681767B1 (en) * 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
ES2284226T3 (es) * 1991-07-02 2007-11-01 Nektar Therapeutics Dispositivo para proporcionar medicamentos en aerosol.
GB9513218D0 (en) * 1995-06-29 1995-09-06 Fisons Plc Inhalation device and method
SE9503344D0 (sv) 1995-09-27 1995-09-27 Astra Ab Inhalation device
TW469832U (en) * 1997-03-14 2001-12-21 Astra Ab Inhalation device
SE9700935D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
US6237591B1 (en) * 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
GEP20043260B (en) 1998-03-16 2004-06-25 Nectar Therapeutics Aerosolized Active Agent Delivery and Device for Realization Thereof
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
UA73924C2 (en) 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
GB9911388D0 (en) 1999-05-18 1999-07-14 Glaxo Group Ltd Dispenser
PT1183060E (pt) 1999-05-20 2006-06-30 Kos Life Sciences Inc Sistema de atomizacao de baixa forca de nebulizacao e baixa retencao
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
GB2360219A (en) 2000-03-18 2001-09-19 Astrazeneca Uk Ltd Inhaler
US6644305B2 (en) 2000-04-14 2003-11-11 Trudell Medical International Nasal inhaler
US6443152B1 (en) * 2001-01-12 2002-09-03 Becton Dickinson And Company Medicament respiratory delivery device
US6550493B2 (en) 2001-06-13 2003-04-22 Baxter International Inc. Vacuum demand valve
US6554023B2 (en) 2001-06-13 2003-04-29 Baxter International Inc. Vacuum demand flow valve
US6863261B2 (en) 2002-03-12 2005-03-08 Baxter International Inc. Valve stop
PT1494732E (pt) 2002-03-20 2008-03-20 Mannkind Corp Aparelho de inalação
US7185651B2 (en) 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
USD507631S1 (en) 2003-03-17 2005-07-19 Baxter International Inc. Valve
USD499793S1 (en) 2003-03-17 2004-12-14 Baxter International Inc. Valve
US7107987B2 (en) * 2004-02-10 2006-09-19 Cfd Research Corporation Spacer for delivery of medications from an inhaler to children and breathing impaired patients
MX2007001903A (es) 2004-08-20 2007-08-02 Mannkind Corp Catalisis de sintesis de dicetopiperazina.
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
AP2007003989A0 (en) * 2004-10-15 2007-06-30 Cipla Ltd An improved spacer
US7493898B2 (en) * 2005-04-13 2009-02-24 Healthline Medical, Inc. Inhalation apparatus
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
US20070101991A1 (en) * 2005-11-08 2007-05-10 Mederio Ag Optimizing release of dry medicament powder
US20070114480A1 (en) * 2005-11-23 2007-05-24 Burke Joseph M Vorticity generators for use with fluid control systems
US7987845B2 (en) * 2006-01-31 2011-08-02 Oriel Therapeutics, Inc. Dry powder inhalers having spiral travel paths, unit dose microcartridges with dry powder, related devices and methods
BRPI0707991B8 (pt) 2006-02-22 2021-05-25 Mannkind Corp métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco
WO2008144106A1 (en) * 2007-05-16 2008-11-27 Aradigm Corporation Burst valve for aerosol device
PT2230934E (pt) 2007-12-14 2012-11-20 Aerodesigns Inc Distribuir produtos alimentares aerossolizáveis
KR101541209B1 (ko) * 2008-03-27 2015-07-31 맨카인드 코포레이션 건조 분말 흡입 시스템
US9358352B2 (en) 2008-06-13 2016-06-07 Mannkind Corporation Dry powder drug delivery system and methods
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
RU2608439C2 (ru) 2008-06-13 2017-01-18 Маннкайнд Корпорейшн Ингалятор для сухого порошка и система для доставки лекарственных средств
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
CN102647979B (zh) 2009-06-12 2015-03-04 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
CN102553038B (zh) * 2010-12-17 2014-07-02 陈庆堂 药粉吸嘴放置盒
EP2694402B1 (en) 2011-04-01 2017-03-22 MannKind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
WO2013114373A1 (en) 2012-02-01 2013-08-08 Protalix Ltd. Inhalable liquid formulations of dnase i
DK3421042T3 (da) 2012-03-07 2024-07-22 Beyond Air Ltd Indånding af nitrogenoxid til behandling af luftvejssygdomme
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
CA2918369C (en) 2013-07-18 2021-06-29 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US20170304459A1 (en) 2014-10-10 2017-10-26 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
TWI595902B (zh) 2016-05-10 2017-08-21 明基材料股份有限公司 攜帶型負壓裝置
BR112021021775A2 (pt) 2019-04-29 2022-01-04 Insmed Inc Composições de pó seco de pró-fármacos de treprostinil e métodos de uso destas
WO2023150747A1 (en) 2022-02-07 2023-08-10 Insmed Incorporated Dry powder compositions of bedaquiline and salts and methods of use thereof

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2570774A (en) * 1947-10-21 1951-10-09 Frank P C Davis Insufflator
US2642063A (en) * 1948-07-31 1953-06-16 Frederick M Turnbull Inhaler
US2581182A (en) * 1950-03-14 1952-01-01 Abbott Lab Inhaler
DE1813993C3 (de) * 1968-12-11 1974-01-24 Paul Ritzau Pari-Werk Kg, 8135 Soecking Vorrichtung zum Zerstäuben und Vernebeln von flüssigen oder pulverförmigen Stoffen
US3838686A (en) * 1971-10-14 1974-10-01 G Szekely Aerosol apparatus for inhalation therapy
DE7916475U1 (de) * 1979-06-08 1979-10-18 Hoechst Ag, 6000 Frankfurt Spriihapplikator
US4368850A (en) * 1980-01-17 1983-01-18 George Szekely Dry aerosol generator
EP0069715B1 (en) * 1981-07-08 1986-11-05 Aktiebolaget Draco Powder inhalator
AU3439884A (en) * 1983-11-28 1985-06-13 Vortran Corp. Single inlet prepackaged inhaler
FI69962C (fi) * 1983-12-28 1986-09-12 Huhtamaeki Oy Inhalationsanordning
US4972830A (en) * 1985-07-31 1990-11-27 Vortran Medical Technology, Inc. Inhalation device and method
US4809692A (en) * 1986-01-31 1989-03-07 Trudell Medical Pediatric asthmatic medication inhaler
SE453566B (sv) * 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
IT1217890B (it) * 1988-06-22 1990-03-30 Chiesi Farma Spa Dispositivo per l'inalazione di aerosol dosati
US4955371A (en) * 1989-05-08 1990-09-11 Transtech Scientific, Inc. Disposable inhalation activated, aerosol device for pulmonary medicine
GB8919131D0 (en) * 1989-08-23 1989-10-04 Riker Laboratories Inc Inhaler
IT1237118B (it) * 1989-10-27 1993-05-18 Miat Spa Inalatore multidose per farmaci in polvere.
US5056511A (en) * 1989-12-14 1991-10-15 Juergen L. Fischer Method and apparatus for compressing, atomizing, and spraying liquid substances
US5507281A (en) * 1990-08-30 1996-04-16 Boehringer Ingelheim Kg Device for initiating a mechanical switching operation in synchronism with the breathing
EP0548152B1 (en) * 1990-09-12 1996-07-24 BISGAARD, Hans An inhaling device
US5062419A (en) * 1991-01-07 1991-11-05 Rider Donald L Nebulizer with valved "T" assembly
FR2676929B1 (fr) * 1991-05-30 1994-02-11 Aerosols Bouchage Ste Fse Inhalateur de poudres.
US5341801A (en) * 1991-12-03 1994-08-30 Sandoz Ltd. Inhaler
GB9214819D0 (en) * 1992-07-13 1992-08-26 Minnesota Mining & Mfg Valve assemblies
DE4237568C1 (de) * 1992-11-06 1994-05-11 Dieter Dipl Ing Dr Med Koehler Verfahren und Vorrichtung zum Erzeugen eines Aerosols
US5584288A (en) * 1994-02-03 1996-12-17 Baldwin; Gene R. Multi-stage mouth-to-mouth resuscitator valve

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006007495A1 (de) * 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit
US8807132B2 (en) 2006-02-17 2014-08-19 Sanofi Sa Dispersing unit

Also Published As

Publication number Publication date
IL116457A0 (en) 1996-03-31
PL320860A1 (en) 1997-11-10
IS4509A (is) 1997-06-18
EP0799067B1 (en) 2001-08-08
IS4508A (is) 1997-06-16
AR000522A1 (es) 1997-07-10
AU698815B2 (en) 1998-11-05
AU4359096A (en) 1996-07-10
ZA9510747B (en) 1996-06-28
NZ298166A (en) 1999-01-28
CZ191397A3 (en) 1997-10-15
EP0799067A1 (en) 1997-10-08
FI972697A7 (fi) 1997-06-23
CN1171056A (zh) 1998-01-21
WO1996019253A1 (en) 1996-06-27
MX9704489A (es) 1997-10-31
ATE203919T1 (de) 2001-08-15
SE9404439D0 (sv) 1994-12-21
TR199501636A1 (tr) 1997-03-21
NO972780L (no) 1997-06-16
SK78297A3 (en) 1998-02-04
US5983893A (en) 1999-11-16
NO972780D0 (no) 1997-06-16
BR9510210A (pt) 1997-11-04
DE69522119D1 (de) 2001-09-13
HUT77661A (hu) 1998-07-28
PL179323B1 (pl) 2000-08-31
FI972697A0 (fi) 1997-06-23
JP3712415B2 (ja) 2005-11-02
CA2207436A1 (en) 1996-06-27
EE9700132A (et) 1997-12-15
TW286285B (cg-RX-API-DMAC10.html) 1996-09-21
JPH10510742A (ja) 1998-10-20

Similar Documents

Publication Publication Date Title
DE69522119T2 (de) Inhaliervorrichtung, verfahren zum verteilen von pharmazeutisch aktiven substanzen und ein verfahren zum verabreichen von dosen von pharmazeutisch aktiven substanzen
DE60121144T2 (de) Eine inhalationsvorrichtung
DE69608561T2 (de) Inhaliervorrichtung und methode
DE69625219T2 (de) Inhalationsvorrichtung
DE69826299T2 (de) Inhalationsgerät
DE69114516T2 (de) Abgabevorrichtung für heilmittel.
EP0611577B1 (de) Pulverinhalator
DE10126808C1 (de) Inhalationsmaske
DE69511102T2 (de) Wiederbelebungsgerät
DE68914932T2 (de) Inhalationsgerät für Aerosolen.
DE69413989T2 (de) Inhalator mit atemstromregelung
EP0167581B1 (de) Inhalationsgerät
EP0895788B1 (de) Inhalationstherapiegerät mit einem Ventil zur Begrenzung des Inspirationsflusses
DE19962110C2 (de) Inhalationsvernebler mit einstückigem Ventilelement
DE69413528T2 (de) Vorrichtung zum deagglomerieren für trockenpulverinhalatoren
DE69316376T2 (de) Inhalationsvorrichtung
DE69918325T2 (de) Atmungsbetätigte aerosolspender
WO1999038555A1 (de) Inhalationsgerät für pulverförmige medikamente
CH657054A5 (de) Dosierinhalator.
DE60022783T2 (de) Vorrichtung zur verabreichung eines gases an einen menschen oder ein tier
EP0009667A1 (de) Inhalationsgerät
EP0626180B1 (de) Mundstück für Inhalationstherapiegeräte
CH680651A5 (cg-RX-API-DMAC10.html)
DE2106794A1 (de) Vorrichtung zum Apphzieren einer abgemessenen Pulvermenge unter Druck
WO2001032246A1 (de) Inhalationsvernebler

Legal Events

Date Code Title Description
8364 No opposition during term of opposition