DE69520383T2 - Quaternäre ammonium immunogenische Konjugate und Immuntest-Reagenz - Google Patents
Quaternäre ammonium immunogenische Konjugate und Immuntest-ReagenzInfo
- Publication number
- DE69520383T2 DE69520383T2 DE69520383T DE69520383T DE69520383T2 DE 69520383 T2 DE69520383 T2 DE 69520383T2 DE 69520383 T DE69520383 T DE 69520383T DE 69520383 T DE69520383 T DE 69520383T DE 69520383 T2 DE69520383 T2 DE 69520383T2
- Authority
- DE
- Germany
- Prior art keywords
- quaternary ammonium
- immunoassay reagent
- immunogenic conjugates
- immunogenic
- conjugates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 238000003018 immunoassay Methods 0.000 title 1
- 230000002163 immunogen Effects 0.000 title 1
- 125000001453 quaternary ammonium group Chemical group 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/816—Alkaloids, amphetamines, and barbiturates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/807—Hapten conjugated with peptide or protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/199,380 US5492841A (en) | 1994-02-18 | 1994-02-18 | Quaternary ammonium immunogenic conjugates and immunoassay reagents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69520383D1 DE69520383D1 (de) | 2001-04-26 |
DE69520383T2 true DE69520383T2 (de) | 2001-10-31 |
Family
ID=22737267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69520383T Expired - Fee Related DE69520383T2 (de) | 1994-02-18 | 1995-01-30 | Quaternäre ammonium immunogenische Konjugate und Immuntest-Reagenz |
Country Status (4)
Country | Link |
---|---|
US (1) | US5492841A (de) |
EP (1) | EP0668504B1 (de) |
JP (1) | JP2731739B2 (de) |
DE (1) | DE69520383T2 (de) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005060057A1 (de) * | 2005-12-15 | 2007-06-28 | Kellner, Karl-Heinz, Dr. | Sandwich-Immunoassay für kleine Haptenmoleküle |
WO2012065912A1 (de) | 2010-11-17 | 2012-05-24 | Karl-Heinz Kellner | Automatenfähiger immunoassay für biogene amine |
WO2021160696A1 (en) | 2020-02-10 | 2021-08-19 | Immundiagnostik Ag | In-vitro diagnosis of histamine intolerance syndrome |
WO2022049213A1 (en) | 2020-09-02 | 2022-03-10 | Immundiagnostik Ag | Test kit and method of determining tryptophan in extracts of faecal samples |
Families Citing this family (78)
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US5545553A (en) * | 1994-09-26 | 1996-08-13 | The Rockefeller University | Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them |
US20020032316A1 (en) * | 1995-03-31 | 2002-03-14 | Cantab Pharmaceuticals Research Limited | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same |
CA2175862A1 (en) * | 1995-05-19 | 1996-11-20 | Roberto Sundoro Wu | Propoxyphene derivatives for immunoassay reagents |
US5741715A (en) * | 1995-05-30 | 1998-04-21 | Roche Diagnostic Systems, Inc. | Quinidine immunoassay and reagents |
EP1125935A3 (de) * | 1995-08-03 | 2001-12-12 | Dade Behring Inc. | Chinidin-Konjugate und ihre Anwendung in Immunoassays |
JPH1026621A (ja) * | 1996-07-12 | 1998-01-27 | Dai Ichi Pure Chem Co Ltd | イムノアッセイ法 |
US5989840A (en) * | 1997-05-29 | 1999-11-23 | Americare International Diagnostics, Inc. | Estimation of active infection by heliobacter pylori |
NZ520579A (en) * | 1997-10-24 | 2004-08-27 | Invitrogen Corp | Recombinational cloning using nucleic acids having recombination sites and methods for synthesizing double stranded nucleic acids |
US7632929B2 (en) * | 2000-04-20 | 2009-12-15 | The Board Of Trustees Of The University Of Arkansas | Methamphetamine-like hapten compounds, linkers, carriers and compositions and uses thereof |
US7202348B2 (en) * | 2000-04-20 | 2007-04-10 | The University Of Arkansas For Medical Sciences | Monoclonal antibody antagonists for treating medical problems associated with d-amphetamine-like drugs |
US6669937B2 (en) * | 2000-04-20 | 2003-12-30 | The Board Of Trustees Of The University Of Arkansas | Monoclonal antibody antagonists for treating medical problems associated with d-amphetamine-like drugs |
US7198924B2 (en) | 2000-12-11 | 2007-04-03 | Invitrogen Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites |
US7214660B2 (en) * | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
US7173003B2 (en) * | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
US7399613B2 (en) * | 2001-10-10 | 2008-07-15 | Neose Technologies, Inc. | Sialic acid nucleotide sugars |
US8008252B2 (en) * | 2001-10-10 | 2011-08-30 | Novo Nordisk A/S | Factor VII: remodeling and glycoconjugation of Factor VII |
US7696163B2 (en) | 2001-10-10 | 2010-04-13 | Novo Nordisk A/S | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
US7157277B2 (en) | 2001-11-28 | 2007-01-02 | Neose Technologies, Inc. | Factor VIII remodeling and glycoconjugation of Factor VIII |
US7179617B2 (en) * | 2001-10-10 | 2007-02-20 | Neose Technologies, Inc. | Factor IX: remolding and glycoconjugation of Factor IX |
US7795210B2 (en) * | 2001-10-10 | 2010-09-14 | Novo Nordisk A/S | Protein remodeling methods and proteins/peptides produced by the methods |
ES2310660T3 (es) | 2002-01-18 | 2009-01-16 | Zymogenetics, Inc. | Citoquina (ligando zcytor17). |
DE60336555D1 (de) * | 2002-06-21 | 2011-05-12 | Novo Nordisk Healthcare Ag | Pegylierte glykoformen von faktor vii |
KR20060003862A (ko) * | 2003-03-14 | 2006-01-11 | 네오스 테크놀로지스, 인크. | 수용성분기폴리머 및 그 접합체 |
EP1613261A4 (de) * | 2003-04-09 | 2011-01-26 | Novo Nordisk As | Intrazelluläre bildung von peptidkonjugaten |
US8791070B2 (en) | 2003-04-09 | 2014-07-29 | Novo Nordisk A/S | Glycopegylated factor IX |
MXPA05010773A (es) * | 2003-04-09 | 2005-12-12 | Neose Technologies Inc | Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos. |
EP1624847B1 (de) | 2003-05-09 | 2012-01-04 | BioGeneriX AG | Zusammensetzungen und Verfahren zur Herstellung von Glykosylierungsmutanten des menschlichen Wachstumshormons |
WO2005012484A2 (en) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Antibody-toxin conjugates |
AU2004293103C1 (en) * | 2003-11-24 | 2010-12-02 | Ratiopharm Gmbh | Glycopegylated erythropoietin |
US8633157B2 (en) * | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
US7842661B2 (en) * | 2003-11-24 | 2010-11-30 | Novo Nordisk A/S | Glycopegylated erythropoietin formulations |
US20080305992A1 (en) * | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
WO2005054438A2 (en) | 2003-12-01 | 2005-06-16 | Invitrogen Corporation | Nucleic acid molecules containing recombination sites and methods of using the same |
KR101237884B1 (ko) * | 2003-12-03 | 2013-02-27 | 바이오제너릭스 에이지 | 글리코 peg화 과립구 콜로니 자극인자 |
US20080318850A1 (en) * | 2003-12-03 | 2008-12-25 | Neose Technologies, Inc. | Glycopegylated Factor Ix |
US7956032B2 (en) * | 2003-12-03 | 2011-06-07 | Novo Nordisk A/S | Glycopegylated granulocyte colony stimulating factor |
US20060040856A1 (en) * | 2003-12-03 | 2006-02-23 | Neose Technologies, Inc. | Glycopegylated factor IX |
US6991911B2 (en) * | 2003-12-15 | 2006-01-31 | Dade Behring Inc. | Assay for entactogens |
US7022492B2 (en) * | 2003-12-15 | 2006-04-04 | Dade Behring Inc. | Ecstasy haptens and immunogens |
US20050130243A1 (en) * | 2003-12-15 | 2005-06-16 | Zheng Yi F. | Assay for entactogens |
BRPI0506741A (pt) * | 2004-01-08 | 2007-05-15 | Neose Technologies Inc | glicosilação de peptìdeos ligados a o |
US7037669B2 (en) * | 2004-03-22 | 2006-05-02 | Dade Behring Inc. | Assays for amphetamine and methamphetamine using stereospecific reagents |
US7115383B2 (en) * | 2004-03-22 | 2006-10-03 | Dade Behring Inc. | Assays for amphetamine and methamphetamine |
US7776564B2 (en) * | 2004-04-30 | 2010-08-17 | Five Prime Therapeutics, Inc. | Stromal cell-derived factor-1 polypeptides, polynucleotides, modulators thereof and methods of use |
US20080300173A1 (en) | 2004-07-13 | 2008-12-04 | Defrees Shawn | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] |
US20090292110A1 (en) * | 2004-07-23 | 2009-11-26 | Defrees Shawn | Enzymatic modification of glycopeptides |
US8268967B2 (en) * | 2004-09-10 | 2012-09-18 | Novo Nordisk A/S | Glycopegylated interferon α |
JP5948627B2 (ja) | 2004-10-29 | 2016-07-20 | レイショファーム ゲーエムベーハー | 線維芽細胞成長因子(fgf)のリモデリングと糖質ペグ化 |
JP2008526864A (ja) * | 2005-01-06 | 2008-07-24 | ネオス テクノロジーズ インコーポレイテッド | 糖断片を用いる糖結合 |
EP1858543B1 (de) * | 2005-01-10 | 2013-11-27 | BioGeneriX AG | Glycopegylierten Granulocyten-Kolonie-stimulierender Faktor |
WO2006105426A2 (en) * | 2005-03-30 | 2006-10-05 | Neose Technologies, Inc. | Manufacturing process for the production of peptides grown in insect cell lines |
US20070154992A1 (en) * | 2005-04-08 | 2007-07-05 | Neose Technologies, Inc. | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants |
US8101183B2 (en) * | 2005-05-06 | 2012-01-24 | Zymogentics, Inc. | Variable region sequences of IL-31 monoclonal antibodies |
EP2301969B1 (de) | 2005-05-06 | 2015-12-23 | ZymoGenetics, Inc. | IL-31-monoklonale Antikörper und Verfahren zu deren Verwendung |
AU2007254715B2 (en) | 2005-05-06 | 2013-08-29 | Zymogenetics, Inc. | Methods of treating pain and inflammation in neuronal tissue using IL-31 antagonists |
US20130216542A1 (en) | 2005-05-06 | 2013-08-22 | Zymogenetics, Inc. | Variable region sequences of il-31 monoclonal antibodies and methods of use |
JP5216580B2 (ja) * | 2005-05-25 | 2013-06-19 | ノヴォ ノルディスク アー/エス | グリコペグ化第ix因子 |
JP2009515508A (ja) * | 2005-08-19 | 2009-04-16 | ネオス テクノロジーズ インコーポレイテッド | グリコpeg化因子viiおよび因子viia |
US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
US20090048440A1 (en) * | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
WO2007147122A2 (en) | 2006-06-15 | 2007-12-21 | The Board Of Trustees Of The University Of Arkansas | Monoclonal antibodies that selectively recognize methamphetamine and methamphetamine like compounds |
CN101516388B (zh) * | 2006-07-21 | 2012-10-31 | 诺和诺德公司 | 通过o-联糖基化序列的肽的糖基化 |
EP2054521A4 (de) * | 2006-10-03 | 2012-12-19 | Novo Nordisk As | Verfahren zur reinigung von polypeptid-konjugate |
KR101556248B1 (ko) * | 2006-10-04 | 2015-09-30 | 노보 노르디스크 에이/에스 | 글리세롤이 연결된 페길화된 당 및 글리코펩티드 |
WO2008073620A2 (en) * | 2006-11-02 | 2008-06-19 | Neose Technologies, Inc. | Manufacturing process for the production of polypeptides expressed in insect cell-lines |
RS52845B (en) * | 2007-04-03 | 2013-12-31 | Biogenerix Ag | TREATMENT PROCEDURES USING GLYCOPEGILATED G-CSF |
EP2140263B1 (de) * | 2007-04-20 | 2017-01-04 | The Board of Trustees of The University of Arkansas | Haptenverbindungen und zusammensetzungen sowie ihre verwendung |
US20090053167A1 (en) * | 2007-05-14 | 2009-02-26 | Neose Technologies, Inc. | C-, S- and N-glycosylation of peptides |
JP2010531135A (ja) * | 2007-06-04 | 2010-09-24 | ノボ ノルディスク アクティーゼルスカブ | N−アセチルグルコサミニルトランスフェラーゼを使用したo結合型グリコシル化 |
US9493499B2 (en) * | 2007-06-12 | 2016-11-15 | Novo Nordisk A/S | Process for the production of purified cytidinemonophosphate-sialic acid-polyalkylene oxide (CMP-SA-PEG) as modified nucleotide sugars via anion exchange chromatography |
US8207112B2 (en) * | 2007-08-29 | 2012-06-26 | Biogenerix Ag | Liquid formulation of G-CSF conjugate |
ES2660036T3 (es) | 2007-12-07 | 2018-03-20 | Zymogenetics, Inc. | Moléculas de anticuerpo humanizadas específicas para IL-31 |
JP5647899B2 (ja) * | 2008-01-08 | 2015-01-07 | ラツィオファルム ゲーエムベーハーratiopharm GmbH | オリゴサッカリルトランスフェラーゼを使用するポリペプチドの複合糖質化 |
EP2257311B1 (de) | 2008-02-27 | 2014-04-16 | Novo Nordisk A/S | Konjugierte faktor-viii-moleküle |
JP5817720B2 (ja) | 2010-05-18 | 2015-11-18 | 味の素株式会社 | 含硫黄アミノ酸誘導体 |
US9023353B2 (en) | 2013-03-13 | 2015-05-05 | The Board Of Trustees Of The University Of Arkansas | Anti-(+)—methamphetamine monoclonal antibodies |
US11793880B2 (en) | 2015-12-04 | 2023-10-24 | Seagen Inc. | Conjugates of quaternized tubulysin compounds |
AU2016363013B2 (en) | 2015-12-04 | 2022-03-10 | Seagen Inc. | Conjugates of quaternized tubulysin compounds |
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BE756391A (nl) * | 1969-10-27 | 1971-03-22 | Agfa Gevaert Nv | Methode voor ontwikkeling van fotografisch materiaal |
US3709808A (en) * | 1970-04-27 | 1973-01-09 | Kendall & Co | Process for the electrodeposition of polymers |
US3709868A (en) | 1971-03-08 | 1973-01-09 | Hoffmann La Roche | Opium alkaloid antigens and antibodies specific therefor |
US3852157A (en) * | 1971-05-14 | 1974-12-03 | Syva Corp | Compounds for enzyme amplification assay |
US4045420A (en) * | 1973-05-29 | 1977-08-30 | Syva Company | Non-oxo-carbonyl containing benzoyl ecgonine and cocaine compounds polypeptide and derivatives thereof |
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US5026827A (en) * | 1988-09-02 | 1991-06-25 | Matsushita Electric Industrial Co., Ltd. | Amphetamine-protein complex as immunogen for obtaining antibodies specific to methamphetamine |
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-
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- 1994-02-18 US US08/199,380 patent/US5492841A/en not_active Expired - Lifetime
-
1995
- 1995-01-30 EP EP95101210A patent/EP0668504B1/de not_active Expired - Lifetime
- 1995-01-30 DE DE69520383T patent/DE69520383T2/de not_active Expired - Fee Related
- 1995-02-17 JP JP7029300A patent/JP2731739B2/ja not_active Expired - Fee Related
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005060057A1 (de) * | 2005-12-15 | 2007-06-28 | Kellner, Karl-Heinz, Dr. | Sandwich-Immunoassay für kleine Haptenmoleküle |
WO2012065912A1 (de) | 2010-11-17 | 2012-05-24 | Karl-Heinz Kellner | Automatenfähiger immunoassay für biogene amine |
DE102011055265A1 (de) | 2010-11-17 | 2012-05-24 | Karl-Heinz Kellner | Automatenfähiger Immunoassay für biogene Amine |
WO2021160696A1 (en) | 2020-02-10 | 2021-08-19 | Immundiagnostik Ag | In-vitro diagnosis of histamine intolerance syndrome |
WO2022049213A1 (en) | 2020-09-02 | 2022-03-10 | Immundiagnostik Ag | Test kit and method of determining tryptophan in extracts of faecal samples |
Also Published As
Publication number | Publication date |
---|---|
EP0668504A1 (de) | 1995-08-23 |
US5492841A (en) | 1996-02-20 |
EP0668504B1 (de) | 2001-03-21 |
DE69520383D1 (de) | 2001-04-26 |
JP2731739B2 (ja) | 1998-03-25 |
JPH07260784A (ja) | 1995-10-13 |
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