DE69504971T2 - Verfahren zur herstellung von cefixime trihydrat - Google Patents

Verfahren zur herstellung von cefixime trihydrat

Info

Publication number
DE69504971T2
DE69504971T2 DE69504971T DE69504971T DE69504971T2 DE 69504971 T2 DE69504971 T2 DE 69504971T2 DE 69504971 T DE69504971 T DE 69504971T DE 69504971 T DE69504971 T DE 69504971T DE 69504971 T2 DE69504971 T2 DE 69504971T2
Authority
DE
Germany
Prior art keywords
tert
producing
cepheme
butoxycarbonylmethoxyimino
aminothiazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69504971T
Other languages
English (en)
Other versions
DE69504971D1 (de
Inventor
Dardes Carlos Picornell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemistry & Health International Bv Rotterdam
Original Assignee
Marcham Trading & Investment Ltd Dublin Ie
Marcham Trading & Investment L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marcham Trading & Investment Ltd Dublin Ie, Marcham Trading & Investment L filed Critical Marcham Trading & Investment Ltd Dublin Ie
Application granted granted Critical
Publication of DE69504971D1 publication Critical patent/DE69504971D1/de
Publication of DE69504971T2 publication Critical patent/DE69504971T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
DE69504971T 1994-06-03 1995-05-10 Verfahren zur herstellung von cefixime trihydrat Expired - Fee Related DE69504971T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH01751/94A CH688319A5 (fr) 1994-06-03 1994-06-03 Procédé pour la préparation du céfixime trihydraté.
PCT/EP1995/001759 WO1995033753A1 (fr) 1994-06-03 1995-05-10 Procede pour la preparation du cefixime trihydrate

Publications (2)

Publication Number Publication Date
DE69504971D1 DE69504971D1 (de) 1998-10-29
DE69504971T2 true DE69504971T2 (de) 1999-05-20

Family

ID=4217712

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69504971T Expired - Fee Related DE69504971T2 (de) 1994-06-03 1995-05-10 Verfahren zur herstellung von cefixime trihydrat

Country Status (9)

Country Link
EP (1) EP0763043B1 (de)
KR (1) KR100223384B1 (de)
AT (1) ATE171454T1 (de)
AU (1) AU2670295A (de)
CH (1) CH688319A5 (de)
DE (1) DE69504971T2 (de)
ES (1) ES2120911B1 (de)
PE (1) PE13296A1 (de)
WO (1) WO1995033753A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204261B1 (en) 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US6420522B1 (en) 1995-06-05 2002-07-16 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β converting enzyme
AT404251B (de) * 1996-08-14 1998-10-27 Biochemie Gmbh Neues kristallines salz von cefixim
PT102061B (pt) * 1997-10-08 2000-06-30 J K Ind Ltd Processo de preparacao de um antibiotico cefalosporina geralmente activo-cefixime
US20040166434A1 (en) 2003-02-21 2004-08-26 Dammel Ralph R. Photoresist composition for deep ultraviolet lithography
DE602005012866D1 (de) * 2004-12-21 2009-04-02 Lupin Ltd Verfahren zur hestellung von cefixim
ES2334685T3 (es) 2005-03-29 2010-03-15 Hetero Drugs Limited Procedimiento mejorado de preparacion de cefixima.
CN1312158C (zh) * 2005-05-20 2007-04-25 天津市医药集团技术发展有限公司 一种头孢克肟的制备方法
WO2016142902A1 (en) * 2015-03-11 2016-09-15 Lupin Limited Cefixime with reduced surface area and high stability
CN111039958B (zh) * 2017-05-31 2022-05-20 郑州大学第一附属医院 头孢地尼的制备方法
JP2023011144A (ja) 2021-07-12 2023-01-24 ウシオ電機株式会社 光源装置、誘電体バリア放電ランプの点灯回路、誘電体バリア放電ランプの点灯方法
CN113968874B (zh) * 2021-10-29 2023-01-31 国药集团威奇达药业有限公司 头孢克肟的精制方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof

Also Published As

Publication number Publication date
ES2120911A1 (es) 1998-11-01
ATE171454T1 (de) 1998-10-15
AU2670295A (en) 1996-01-04
KR970703348A (ko) 1997-07-03
WO1995033753A1 (fr) 1995-12-14
DE69504971D1 (de) 1998-10-29
EP0763043A1 (de) 1997-03-19
CH688319A5 (fr) 1997-07-31
PE13296A1 (es) 1996-05-10
ES2120911B1 (es) 1999-07-01
KR100223384B1 (ko) 1999-10-15
EP0763043B1 (de) 1998-09-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CHEMISTRY & HEALTH INTERNATIONAL B.V., ROTTERDAM,

8339 Ceased/non-payment of the annual fee