DE69434097D1 - Apoptose induzierender monoklonaler antikörper - Google Patents

Apoptose induzierender monoklonaler antikörper

Info

Publication number
DE69434097D1
DE69434097D1 DE69434097T DE69434097T DE69434097D1 DE 69434097 D1 DE69434097 D1 DE 69434097D1 DE 69434097 T DE69434097 T DE 69434097T DE 69434097 T DE69434097 T DE 69434097T DE 69434097 D1 DE69434097 D1 DE 69434097D1
Authority
DE
Germany
Prior art keywords
antibody
monoclonal antibody
apoptose
myelocytic
inducing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69434097T
Other languages
English (en)
Other versions
DE69434097T2 (de
Inventor
Naoshi Fukushima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69434097D1 publication Critical patent/DE69434097D1/de
Publication of DE69434097T2 publication Critical patent/DE69434097T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DE69434097T 1993-09-03 1994-09-02 Apoptose induzierender monoklonaler antikörper Expired - Fee Related DE69434097T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP24211093 1993-09-03
JP05242110 1993-09-03
PCT/JP1994/001453 WO1995006748A1 (fr) 1993-09-03 1994-09-02 Anticorps monoclonal permettant d'induire une apoptose

Publications (2)

Publication Number Publication Date
DE69434097D1 true DE69434097D1 (de) 2004-12-02
DE69434097T2 DE69434097T2 (de) 2006-02-02

Family

ID=17084452

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69434097T Expired - Fee Related DE69434097T2 (de) 1993-09-03 1994-09-02 Apoptose induzierender monoklonaler antikörper

Country Status (19)

Country Link
US (4) US5840344A (de)
EP (1) EP0721015B1 (de)
KR (1) KR100241863B1 (de)
CN (1) CN1046314C (de)
AT (1) ATE280835T1 (de)
AU (1) AU692466B2 (de)
CA (1) CA2169950A1 (de)
CZ (1) CZ294359B6 (de)
DE (1) DE69434097T2 (de)
FI (1) FI960567A0 (de)
HU (1) HU222989B1 (de)
NO (1) NO960684D0 (de)
PL (1) PL181783B1 (de)
RU (1) RU2202615C2 (de)
SK (1) SK281964B6 (de)
TW (1) TW426687B (de)
UA (1) UA50708C2 (de)
WO (1) WO1995006748A1 (de)
ZA (1) ZA946767B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE280835T1 (de) * 1993-09-03 2004-11-15 Chugai Pharmaceutical Co Ltd Apoptose induzierender monoklonaler antikörper
AU2232597A (en) * 1996-03-06 1997-09-22 Chugai Seiyaku Kabushiki Kaisha Method of screening apoptosis inducing substances
US6828426B1 (en) 1996-07-15 2004-12-07 Chugai Seiyaku Kabushiki Kaisha VEGF-like factor
DE69839492D1 (de) * 1997-09-11 2008-06-26 Chugai Pharmaceutical Co Ltd Monoklonale antikörper zur apoptosis-induzierung
US7531643B2 (en) * 1997-09-11 2009-05-12 Chugai Seiyaku Kabushiki Kaisha Monoclonal antibody inducing apoptosis
EP1167388A4 (de) * 1999-03-10 2002-05-29 Chugai Pharmaceutical Co Ltd Apoptose induzierendes einzelsträngiges fv
US7696325B2 (en) 1999-03-10 2010-04-13 Chugai Seiyaku Kabushiki Kaisha Polypeptide inducing apoptosis
US20040058393A1 (en) * 2000-04-17 2004-03-25 Naoshi Fukishima Agonist antibodies
DE60133479T2 (de) 2000-10-20 2009-04-16 Chugai Seiyaku K.K. Modifizierter tpo-agonisten antikörper
CN1308447C (zh) * 2000-10-20 2007-04-04 中外制药株式会社 低分子化的激动剂抗体
US7195771B1 (en) 2000-11-21 2007-03-27 Kimberly-Clark Worldwide, Inc. Water-soluble lotions for paper products
AU2002361642A1 (en) * 2001-11-16 2003-06-10 The University Of Tennessee Research Corporation Recombinant antibody fusion proteins and methods for detection of apoptotic cells
ATE414105T1 (de) 2002-10-11 2008-11-15 Chugai Pharmaceutical Co Ltd Zelltod-induzierender wirkstoff
JP2004279086A (ja) * 2003-03-13 2004-10-07 Konica Minolta Holdings Inc 放射線画像変換パネル及び放射線画像変換パネルの製造方法
EP1609803A4 (de) * 2003-03-31 2006-05-24 Chugai Pharmaceutical Co Ltd Modifizierter antikörper gegen cd22 und anwendungen dafür
AU2004297109A1 (en) * 2003-12-12 2005-06-23 Chugai Seiyaku Kabushiki Kaisha Cell death inducing agent
TW200530269A (en) 2003-12-12 2005-09-16 Chugai Pharmaceutical Co Ltd Anti-Mpl antibodies
WO2005056602A1 (ja) * 2003-12-12 2005-06-23 Chugai Seiyaku Kabushiki Kaisha アゴニスト活性を有する改変抗体のスクリーニング方法
TW200530266A (en) * 2003-12-12 2005-09-16 Chugai Pharmaceutical Co Ltd Method of reinforcing antibody activity
US9493569B2 (en) 2005-03-31 2016-11-15 Chugai Seiyaku Kabushiki Kaisha Structural isomers of sc(Fv)2
EP1927367A4 (de) * 2005-05-18 2009-08-12 Univ Tokushima Neues pharmazeutisches mittel mit anti-hla-antikörper
KR101360671B1 (ko) 2005-06-10 2014-02-07 추가이 세이야쿠 가부시키가이샤 ｓｃ（Ｆｖ）２를 함유하는 의약조성물
AU2006256041B2 (en) * 2005-06-10 2012-03-29 Chugai Seiyaku Kabushiki Kaisha Stabilizer for protein preparation comprising meglumine and use thereof
WO2007100892A2 (en) * 2006-02-28 2007-09-07 The Board Of Trustees Of The Leland Stanford Junior University Trojan horse immunotherapy
AR061986A1 (es) * 2006-07-13 2008-08-10 Chugai Pharmaceutical Co Ltd Agentes inductores de muerte celular
CL2008000719A1 (es) * 2007-03-12 2008-09-05 Univ Tokushima Chugai Seiyaku Agente terapeutico para cancer resistente a agentes quimioterapeuticos que comprende un anticuerpo que reconoce hla de clase i como ingrediente activo; composicion farmaceutica que comprende dicho anticuerpo; y metodo para tratar cancer resistente a
KR20170108946A (ko) 2014-12-05 2017-09-27 메모리얼 슬로안-케터링 캔서 센터 Fc 수용체-유사 5를 표적화하는 키메라 항원 수용체 및 그의 용도
BR112018011336A2 (pt) 2015-12-04 2018-12-04 Memorial Sloan-Kettering Cancer Center anticorpo anti-fcrl5 isolado ou um fragmento de ligação ao antígeno do mesmo, anticorpo scfv anti-fcrl5 isolado, anticorpo isolado ou porção de ligação ao antígeno do mesmo, composição, imunoconjugado, molécula biespecífica, ácido nucleico isolado, vetor de expressão, célula hospedeira, método para detectar fcrl5 em uma célula ou tecido inteiro, método para tratar câncer em um indivíduo, uso do anticorpo ou fragmento de ligação ao antígeno do mesmo, kit para tratar câncer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE280835T1 (de) * 1993-09-03 2004-11-15 Chugai Pharmaceutical Co Ltd Apoptose induzierender monoklonaler antikörper
AU2232597A (en) * 1996-03-06 1997-09-22 Chugai Seiyaku Kabushiki Kaisha Method of screening apoptosis inducing substances
DE69839492D1 (de) * 1997-09-11 2008-06-26 Chugai Pharmaceutical Co Ltd Monoklonale antikörper zur apoptosis-induzierung
EP1167388A4 (de) * 1999-03-10 2002-05-29 Chugai Pharmaceutical Co Ltd Apoptose induzierendes einzelsträngiges fv

Also Published As

Publication number Publication date
RU2202615C2 (ru) 2003-04-20
UA50708C2 (uk) 2002-11-15
EP0721015A1 (de) 1996-07-10
FI960567A (fi) 1996-02-07
EP0721015B1 (de) 2004-10-27
US6267959B1 (en) 2001-07-31
KR100241863B1 (ko) 2000-03-02
US20030147894A1 (en) 2003-08-07
US5840344A (en) 1998-11-24
SK25596A3 (en) 1996-10-02
CN1046314C (zh) 1999-11-10
US20010001712A1 (en) 2001-05-24
ZA946767B (en) 1995-04-03
PL181783B1 (pl) 2001-09-28
US6759043B2 (en) 2004-07-06
HU222989B1 (hu) 2004-01-28
CZ294359B6 (cs) 2004-12-15
CN1130405A (zh) 1996-09-04
AU692466B2 (en) 1998-06-11
WO1995006748A1 (fr) 1995-03-09
ATE280835T1 (de) 2004-11-15
CZ61796A3 (en) 1996-06-12
HUT74594A (en) 1997-01-28
NO960684L (no) 1996-02-21
DE69434097T2 (de) 2006-02-02
CA2169950A1 (en) 1995-03-09
NO960684D0 (no) 1996-02-21
FI960567A0 (fi) 1996-02-07
HU9600206D0 (en) 1996-03-28
TW426687B (en) 2001-03-21
PL313260A1 (en) 1996-06-24
AU7546694A (en) 1995-03-22
EP0721015A4 (de) 1999-03-31
SK281964B6 (sk) 2001-09-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee