DE69427122T2 - Kompetitiver immunotest unter verwendung eines bindenden proteins in multiklonaler antikoerperstruktur - Google Patents

Kompetitiver immunotest unter verwendung eines bindenden proteins in multiklonaler antikoerperstruktur

Info

Publication number
DE69427122T2
DE69427122T2 DE69427122T DE69427122T DE69427122T2 DE 69427122 T2 DE69427122 T2 DE 69427122T2 DE 69427122 T DE69427122 T DE 69427122T DE 69427122 T DE69427122 T DE 69427122T DE 69427122 T2 DE69427122 T2 DE 69427122T2
Authority
DE
Germany
Prior art keywords
immunotest
multiclonal
competitive
binding protein
body structure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69427122T
Other languages
English (en)
Other versions
DE69427122D1 (de
Inventor
J Beggs
J Sohn
J Herrmann
C Hsu
J Hawksworth
S Pinkus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE69427122D1 publication Critical patent/DE69427122D1/de
Application granted granted Critical
Publication of DE69427122T2 publication Critical patent/DE69427122T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/971—Capture of complex after antigen-antibody reaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69427122T 1993-02-24 1994-02-24 Kompetitiver immunotest unter verwendung eines bindenden proteins in multiklonaler antikoerperstruktur Expired - Lifetime DE69427122T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/021,942 US5434087A (en) 1993-02-24 1993-02-24 Folate immunoassay utilizing folate binding protein in a multiclonal antibody format
PCT/US1994/002073 WO1994019695A1 (en) 1993-02-24 1994-02-24 Competitive immunoassay utilizing binding protein in a multiclonal antibody format

Publications (2)

Publication Number Publication Date
DE69427122D1 DE69427122D1 (de) 2001-05-23
DE69427122T2 true DE69427122T2 (de) 2002-01-03

Family

ID=21806985

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427122T Expired - Lifetime DE69427122T2 (de) 1993-02-24 1994-02-24 Kompetitiver immunotest unter verwendung eines bindenden proteins in multiklonaler antikoerperstruktur

Country Status (8)

Country Link
US (1) US5434087A (de)
EP (1) EP0686263B1 (de)
JP (1) JP3392868B2 (de)
AU (1) AU6176594A (de)
CA (1) CA2156736C (de)
DE (1) DE69427122T2 (de)
ES (1) ES2157979T3 (de)
WO (1) WO1994019695A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19713088C1 (de) * 1997-03-27 1998-11-26 Reiner Dr Probst Verfahren und Blutabnahmegefäß zur Aufbereitung von Blutproben für die Homocystein- und/oder Folatbestimmung
GB9719140D0 (en) * 1997-09-09 1997-11-12 Ortho Clinical Diagnostics Ligand binding sufaces
CN100399030C (zh) 1999-11-16 2008-07-02 杰南技术公司 用于vegf的elisa
CH697021A5 (de) * 2003-06-26 2008-03-31 Merck Eprova Ag Stabile pharmazeutische Zusammensetzungen von 5, 10-Methylentetrahydrofolat.
CN100483134C (zh) * 2003-06-30 2009-04-29 希森美康株式会社 免疫层析装置
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US20060270922A1 (en) 2004-07-13 2006-11-30 Brauker James H Analyte sensor
US7713574B2 (en) 2004-07-13 2010-05-11 Dexcom, Inc. Transcutaneous analyte sensor
US8652788B2 (en) * 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
US8835120B2 (en) * 2009-12-02 2014-09-16 Abbott Laboratories Assay for cardiac troponin-T (cTnT)
US10059710B2 (en) 2016-02-17 2018-08-28 Merck & Cie Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid
JP6946926B2 (ja) * 2017-10-23 2021-10-13 東ソー株式会社 ビタミン類の遊離に使用する凍結乾燥試薬
CN113933502B (zh) * 2021-10-19 2024-02-02 青岛汉唐生物科技有限公司 一种免疫荧光层析法定量检测叶酸的检测卡及试剂盒

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028465A (en) * 1975-11-10 1977-06-07 Bio-Rad Laboratories Assay method for serum folate
US4146602A (en) * 1977-01-27 1979-03-27 Becton, Dickinson & Company Simultaneous radioassay of folate and vitamin B12
US4271140A (en) * 1978-01-23 1981-06-02 Baxter Travenol Laboratories, Inc. Method and composition for double receptor, specific binding assays
US4188189A (en) * 1978-04-04 1980-02-12 University Patents, Inc. Quantitative testing for vitamin B12
US4351822A (en) * 1978-04-04 1982-09-28 University Patents, Inc. Quantitative testing for vitamin B12
US4423154A (en) * 1978-06-26 1983-12-27 Becton Dickinson And Company Simultaneous radioassay of folate and vitamin B12
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
US4418151A (en) * 1981-03-30 1983-11-29 Rohm And Haas Company Assay process with non-boiling denaturation
US4451571A (en) * 1981-04-06 1984-05-29 University Patents, Inc. Preparation of samples for vitamin B12 and/or folate assay and assay
US4350659A (en) * 1981-07-30 1982-09-21 Corning Glass Works Stabilization of sensitive biologically active intermediate metabolites such as folic acid derivatives
US4399228A (en) * 1981-07-30 1983-08-16 Corning Glass Works Polate competitive protein binding assay
US5011771A (en) * 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
GB2161165A (en) * 1984-06-12 1986-01-08 Cambridge Patent Dev Secondary antibodies
US4950612A (en) * 1987-12-16 1990-08-21 Microgenics Corporation Peroxy acid pretreatment in vitamin B12 assay
JPH03503566A (ja) * 1988-01-28 1991-08-08 イー・アイ・デユポン・ド・ネモアース・アンド・コンパニー 天然結合タンパク質に対するモノクローナル抗体を用いたイムノアツセイ
US5244630A (en) * 1988-04-22 1993-09-14 Abbott Laboratories Device for performing solid-phase diagnostic assay
ES2124734T3 (es) * 1991-05-30 1999-02-16 Abbott Lab Analisis con captura de iones que recubre a un elemento de fijacion asociado con carboximetilamilosa.
WO1993014405A1 (en) * 1992-01-06 1993-07-22 Baxter Diagnostics Inc. Binding protein capture assay

Also Published As

Publication number Publication date
EP0686263A1 (de) 1995-12-13
WO1994019695A1 (en) 1994-09-01
CA2156736A1 (en) 1994-09-01
US5434087A (en) 1995-07-18
JP3392868B2 (ja) 2003-03-31
AU6176594A (en) 1994-09-14
DE69427122D1 (de) 2001-05-23
EP0686263B1 (de) 2001-04-18
CA2156736C (en) 2008-01-29
JPH08507603A (ja) 1996-08-13
EP0686263A4 (de) 1998-06-10
ES2157979T3 (es) 2001-09-01

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Legal Events

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