DE3854194T2 - Monoklonale antikörper gegen glykosyliertes albumin, hybride zellinien, die diese antikörper produzieren, sowie deren verwendung. - Google Patents

Monoklonale antikörper gegen glykosyliertes albumin, hybride zellinien, die diese antikörper produzieren, sowie deren verwendung.

Info

Publication number
DE3854194T2
DE3854194T2 DE3854194T DE3854194T DE3854194T2 DE 3854194 T2 DE3854194 T2 DE 3854194T2 DE 3854194 T DE3854194 T DE 3854194T DE 3854194 T DE3854194 T DE 3854194T DE 3854194 T2 DE3854194 T2 DE 3854194T2
Authority
DE
Germany
Prior art keywords
produce
monoclonal antibodies
cell lines
hybrid cell
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3854194T
Other languages
English (en)
Other versions
DE3854194D1 (de
Inventor
Margo Cohen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exocell Inc
Original Assignee
Exocell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exocell Inc filed Critical Exocell Inc
Publication of DE3854194D1 publication Critical patent/DE3854194D1/de
Application granted granted Critical
Publication of DE3854194T2 publication Critical patent/DE3854194T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
DE3854194T 1988-01-25 1988-12-15 Monoklonale antikörper gegen glykosyliertes albumin, hybride zellinien, die diese antikörper produzieren, sowie deren verwendung. Expired - Lifetime DE3854194T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/147,363 US5223392A (en) 1988-01-25 1988-01-25 Monoclonal antibodies against glycated albumin, hybrid cell lines producing these antibodies, and use therefore
PCT/US1988/004446 WO1989006798A1 (en) 1988-01-25 1988-12-15 Monoclonal antibodies against glycated albumin, hybrid cell lines producing these antibodies, and use therefore

Publications (2)

Publication Number Publication Date
DE3854194D1 DE3854194D1 (de) 1995-08-24
DE3854194T2 true DE3854194T2 (de) 1996-03-21

Family

ID=22521270

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3854194T Expired - Lifetime DE3854194T2 (de) 1988-01-25 1988-12-15 Monoklonale antikörper gegen glykosyliertes albumin, hybride zellinien, die diese antikörper produzieren, sowie deren verwendung.

Country Status (7)

Country Link
US (1) US5223392A (de)
EP (1) EP0358739B1 (de)
JP (1) JP3026818B2 (de)
AT (1) ATE125362T1 (de)
AU (1) AU3066489A (de)
DE (1) DE3854194T2 (de)
WO (1) WO1989006798A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284777A (en) * 1991-03-04 1994-02-08 Isolab, Inc. Combined glycated hemoglobin and immunoturbidometric glycated albumin assay from whole blood lysate
US5624804A (en) * 1991-12-20 1997-04-29 The Rockefeller University Immunochemical detection of In vivo advanced glycosylation end products
US5518720A (en) * 1992-12-30 1996-05-21 Exocell, Inc. Treatment of complications of diabetes with substances reactive with the fructosyl-lysine structure in glycated albumin
DE4308532A1 (de) * 1993-03-17 1994-09-22 Boehringer Mannheim Gmbh Monoklonale Antikörper gegen in vivo glykiertes Albumin
US6551593B1 (en) * 1995-02-10 2003-04-22 Millennium Pharmaceuticals, Inc. Treatment of Inflammatory bowel disease by inhibiting binding and/or signalling through α 4 β 7 and its ligands and madcam
US7750137B2 (en) * 1995-09-01 2010-07-06 Millennium Pharmaceuticals, Inc. Mucosal vascular addressins
US7803904B2 (en) * 1995-09-01 2010-09-28 Millennium Pharmaceuticals, Inc. Mucosal vascular addressing and uses thereof
US5695949A (en) * 1995-04-07 1997-12-09 Lxn Corp. Combined assay for current glucose level and intermediate or long-term glycemic control
CN1165300A (zh) 1995-10-18 1997-11-19 株式会社京都第一科学 用于测定糖化白蛋白的干检验装置
US5811242A (en) * 1995-10-24 1998-09-22 Tokuyama Corporation Marker and reagent for diabetes mellitus and diabetes mellitus complication
US6355680B1 (en) * 1996-02-20 2002-03-12 Exocell, Inc. Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies
US5908925A (en) * 1996-06-27 1999-06-01 Exocell, Inc. Genetically engineered immunoglobulins with specificity for glycated albumin
US7147851B1 (en) * 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
US6475743B1 (en) 1998-10-02 2002-11-05 Ischemia Technologies, Inc. Marker useful for detection and measurement of free radical damage and method
US7449338B2 (en) * 1998-10-02 2008-11-11 Ischemia Technologies, Inc. Tests for the rapid evaluation of ischemic states and kits
US20030215359A1 (en) * 1998-10-02 2003-11-20 Ischemia Technologies, Inc. Tests for the rapid evaluation of ischemic states and kits
US7070937B1 (en) 1998-10-02 2006-07-04 Ischemia Technologies, Inc. Marker useful for detection and measurement of free radical damage and method
US20050142613A1 (en) * 1998-10-02 2005-06-30 David Bar-Or Test for the rapid evaluation of ischemic states and kits
US7297544B2 (en) * 1998-10-02 2007-11-20 Ischemia Technologies, Inc. Tests for the rapid evaluation of ischemic states and kits
IL145957A0 (en) * 1999-04-15 2002-07-25 Fox Chase Cancer Ct A pharmaceutical composition comprising an agent which binds with 3-deoxyglucosone
US6835545B2 (en) 2000-05-08 2004-12-28 President And Fellows Of Harvard College Methods, products and treatments for diabetes
NZ582769A (en) * 2002-10-09 2011-11-25 Dmi Biosciences Inc Diagnosis and monitoring of inflammation, ischemia and appendicitis
US7074194B2 (en) * 2003-05-19 2006-07-11 Ischemia Technologies, Inc. Apparatus and method for risk stratification of patients with chest pain of suspected cardiac origin
ATE509275T1 (de) * 2003-09-23 2011-05-15 Epinex Diagnostic Inc Schnelltest für glykiertes albumin
US20060089316A1 (en) * 2004-10-25 2006-04-27 Brown Truman R Method for reducing a susceptibility to tumor formation induced by 3-deoxyglucosone and precursors thereof
WO2006086098A2 (en) 2005-01-06 2006-08-17 President And Fellows Of Harvard College Mass spectrometric methods and products
US20070015291A1 (en) * 2005-07-18 2007-01-18 Smith Henry J Rapid test for glycated albumin in blood
US20090042237A1 (en) * 2007-08-06 2009-02-12 Henry John Smith Aptamer based point-of-care test for glycated albumin
US9817001B2 (en) 2008-05-27 2017-11-14 Boston Heart Diagnostics Corporation Methods for determining LDL cholesterol treatment
US8470541B1 (en) 2008-09-27 2013-06-25 Boston Heart Diagnostics Corporation Methods for separation and immuno-detection of biomolecules, and apparatus related thereto
US20100167306A1 (en) * 2008-12-26 2010-07-01 Henry John Smith Rapid test for glycated albumin in saliva
US9068006B2 (en) 2010-08-25 2015-06-30 President And Fellows Of Harvard College Glycated CD59 peptides, their preparation, and uses thereof
CN107998388B (zh) 2011-05-02 2023-07-14 千禧制药公司 抗α4β7抗体的制剂
UA116189C2 (uk) 2011-05-02 2018-02-26 Мілленніум Фармасьютікалз, Інк. КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
US8765377B2 (en) 2011-10-13 2014-07-01 Boston Heart Diagnostics Corporation Compositions and methods for treating and preventing coronary heart disease
EP2874646A4 (de) * 2012-04-17 2016-07-06 Univ Aarhus Sorcs1 zur verwendung bei der behandlung von adipositas und übergewicht
CN102914656B (zh) * 2012-07-23 2014-10-29 四川新健康成生物股份有限公司 间接免疫法糖化血清白蛋白检测试剂盒
US9828624B2 (en) 2013-07-24 2017-11-28 Boston Heart Diagnostics Corporation Driving patient compliance with therapy
EP3220810A4 (de) 2014-11-17 2018-05-16 Boston Heart Diagnostic Corporation Beurteilung des risikos für herz-kreislauf-erkrankungen
CN104990879A (zh) * 2015-07-02 2015-10-21 董静平 血清糖化白蛋白含量测定方法及测定试剂盒
EP3726215A4 (de) 2017-12-12 2022-01-19 DxGen Corp. Kieselsäurenanopartikel zur biomarkerdiagnose und verfahren zur herstellung davon
CN109828112B (zh) * 2019-03-02 2022-02-15 浙江康特生物科技有限公司 糖化白蛋白抗体复合物制备方法及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4629692A (en) * 1982-12-06 1986-12-16 Miles Laboratories, Inc. Immunoassay for nonenzymatically glucosylated proteins and protein fragments an index of glycemia
US4837170A (en) * 1986-01-20 1989-06-06 Otsuka Pharmaceutical Co., Ltd. Monoclonal antibody, measuring method of glucosylated protein by utilizing the monoclonal antibody, and kit therefor
US4797473A (en) * 1986-06-25 1989-01-10 Regents Of The University Of Minnesota Monoclonal antibodies to unreduced, nonenzymatically-glycated proteins
DE3781745T2 (de) * 1986-08-22 1993-02-04 Miles Inc Antikoerper zur verwendung fuer die bestimmung von menschlichem glycoalbumin.

Also Published As

Publication number Publication date
EP0358739B1 (de) 1995-07-19
DE3854194D1 (de) 1995-08-24
EP0358739A1 (de) 1990-03-21
EP0358739A4 (en) 1991-07-03
JPH02503059A (ja) 1990-09-27
JP3026818B2 (ja) 2000-03-27
WO1989006798A1 (en) 1989-07-27
US5223392A (en) 1993-06-29
AU3066489A (en) 1989-08-11
ATE125362T1 (de) 1995-08-15

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