DE69425158D1 - Optisches probe-analysesystem und verfahren - Google Patents

Optisches probe-analysesystem und verfahren

Info

Publication number
DE69425158D1
DE69425158D1 DE69425158T DE69425158T DE69425158D1 DE 69425158 D1 DE69425158 D1 DE 69425158D1 DE 69425158 T DE69425158 T DE 69425158T DE 69425158 T DE69425158 T DE 69425158T DE 69425158 D1 DE69425158 D1 DE 69425158D1
Authority
DE
Germany
Prior art keywords
analyte
measurement
testing substrate
area
labeled reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69425158T
Other languages
English (en)
Other versions
DE69425158T2 (de
Inventor
E Chu
Lian Tao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
E-Y Laboratories Inc
Original Assignee
E-Y Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E-Y Laboratories Inc filed Critical E-Y Laboratories Inc
Publication of DE69425158D1 publication Critical patent/DE69425158D1/de
Application granted granted Critical
Publication of DE69425158T2 publication Critical patent/DE69425158T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/8483Investigating reagent band
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/90Determination of colour characteristics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • G01N15/1433Signal processing using image recognition
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1765Method using an image detector and processing of image signal
    • G01N2021/177Detector of the video camera type
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59Transmissivity
    • G01N21/5907Densitometers
    • G01N2021/5915Processing scan data in densitometry
    • G01N2021/5919Determining total density of a zone
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59Transmissivity
    • G01N21/5907Densitometers
    • G01N2021/5915Processing scan data in densitometry
    • G01N2021/5923Determining zones of density; quantitating spots
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59Transmissivity
    • G01N21/5907Densitometers
    • G01N2021/5915Processing scan data in densitometry
    • G01N2021/593Correcting from the background density
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59Transmissivity
    • G01N21/5907Densitometers
    • G01N2021/5915Processing scan data in densitometry
    • G01N2021/5934Averaging on a zone
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/8483Investigating reagent band
    • G01N2021/8488Investigating reagent band the band presenting reference patches
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10024Color image
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Holo Graphy (AREA)
DE69425158T 1993-02-26 1994-02-24 Optisches probe-analysesystem und verfahren Expired - Lifetime DE69425158T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2311393A 1993-02-26 1993-02-26
PCT/US1994/001925 WO1994019767A1 (en) 1993-02-26 1994-02-24 Optical specimen analysis system and method

Publications (2)

Publication Number Publication Date
DE69425158D1 true DE69425158D1 (de) 2000-08-10
DE69425158T2 DE69425158T2 (de) 2001-03-15

Family

ID=21813206

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69425158T Expired - Lifetime DE69425158T2 (de) 1993-02-26 1994-02-24 Optisches probe-analysesystem und verfahren

Country Status (9)

Country Link
US (2) US5717778A (de)
EP (1) EP0731951B1 (de)
JP (1) JP3093270B2 (de)
AT (1) ATE194431T1 (de)
DE (1) DE69425158T2 (de)
DK (1) DK0731951T3 (de)
ES (1) ES2150985T3 (de)
HK (1) HK1014598A1 (de)
WO (1) WO1994019767A1 (de)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0618917U (ja) * 1992-08-19 1994-03-11 進一 安田 マーキング装置
ES2150985T3 (es) * 1993-02-26 2000-12-16 E Y Lab Inc Procedimiento y sistema de analisis optico de muestras.
CA2215193C (en) * 1995-03-17 2004-05-11 Kureha Kagaku Kogyo Kabushiki Kaisha Biochemical information processing apparatus, biochemical information processing method, and biochemical information recording medium
DE19611347A1 (de) * 1996-03-22 1997-09-25 Boehringer Mannheim Gmbh System zur quantitativen ortsaufgelösten Auswertung von Testelementen
GB9700729D0 (en) * 1997-01-15 1997-03-05 Axis Biochemicals As System
US6514461B1 (en) * 1997-02-14 2003-02-04 Escreen, Inc. System for automatically testing a fluid specimen
EP0902394B1 (de) * 1997-09-11 2004-11-17 Randox Laboratories Ltd. Verfahren und Gerät zur Bildanalyse
EP1060455A4 (de) * 1998-02-10 2002-08-07 Ey Lab Inc Reflektometersystem mit kompensation fur die topographie des probenhalters und mit synchroner eliminierung des systembedingten rauschens
US6702988B1 (en) * 1999-04-21 2004-03-09 Peter J. Sagona Automatic on-site drug testing system and method
ES2185592T5 (es) * 1999-05-19 2009-03-01 Eppendorf Array Technologies Procedimiento para la identificacion y/o cuantificacion de un compuesto diana.
EP1126272A1 (de) * 2000-02-18 2001-08-22 Advanced Array Technologies S.A. Vorrichtung zum Nachweis und/oder Mengenbestimmung eines Niederschlags auf der Oberfläche eines festen Trägers
EP1096252A3 (de) * 1999-10-29 2002-01-02 Helena Laboratories Corporation Abtastdensitometer und Verfahren zur Datenauswertung
EP1226546B1 (de) * 1999-10-29 2007-03-21 Cytyc Corporation Vorrichtung und verfahren zur überprüfung die ortung aussagefähiger bildbereiche innerhalb einer probe in einem abbildungssystem
US6665060B1 (en) 1999-10-29 2003-12-16 Cytyc Corporation Cytological imaging system and method
US7006674B1 (en) 1999-10-29 2006-02-28 Cytyc Corporation Apparatus and methods for verifying the location of areas of interest within a sample in an imaging system
US7369304B2 (en) * 1999-10-29 2008-05-06 Cytyc Corporation Cytological autofocusing imaging systems and methods
US7062077B1 (en) * 1999-10-29 2006-06-13 Helena Laboratories Corporation Scanner densitometer and data evaluation method
US6661501B1 (en) 1999-10-29 2003-12-09 Cytyc Corporation Cytological stain composition including verification characteristic
US6836559B2 (en) * 2000-03-09 2004-12-28 The Regents Of The University Of California Automated video-microscopic imaging and data acquisition system for colloid deposition measurements
TWI220927B (en) * 2000-05-12 2004-09-11 Rong-Seng Chang Method for producing a micro-carrier
US20080033595A1 (en) * 2000-11-16 2008-02-07 Packes John M Jr Method of outputting offers at a vending machine field
US20030104492A1 (en) * 2000-12-15 2003-06-05 Albert Chu Flow-through membrane assays for carbohydrates using labeled lectins
US20040166593A1 (en) * 2001-06-22 2004-08-26 Nolte David D. Adaptive interferometric multi-analyte high-speed biosensor
US6993172B2 (en) * 2001-06-29 2006-01-31 Agilent Technologies, Inc. Method and system for automated outlying feature and outlying feature background detection during processing of data scanned from a molecular array
US6847451B2 (en) * 2002-05-01 2005-01-25 Lifescan, Inc. Apparatuses and methods for analyte concentration determination
US7239682B2 (en) * 2002-11-12 2007-07-03 Carnegie Mellon University Timing recovery system and method
US20040131258A1 (en) * 2003-01-06 2004-07-08 Myung Ho Kim Method of pattern recognition of computer generated images and its application for protein 2D gel image diagnosis of a disease
DE102004023402A1 (de) 2004-05-12 2005-12-08 Roche Diagnostics Gmbh Verfahren zur Erhöhung des dynamischen Messbereichs von auf spezifischen Bindereaktionen basierenden, insbesondere immunologischen Testelementen
JP4715996B2 (ja) * 2004-12-03 2011-07-06 セイコーエプソン株式会社 分光分析装置および分光分析方法
US20070023643A1 (en) * 2005-02-01 2007-02-01 Nolte David D Differentially encoded biological analyzer planar array apparatus and methods
US7663092B2 (en) * 2005-02-01 2010-02-16 Purdue Research Foundation Method and apparatus for phase contrast quadrature interferometric detection of an immunoassay
US7910356B2 (en) 2005-02-01 2011-03-22 Purdue Research Foundation Multiplexed biological analyzer planar array apparatus and methods
EP1843147A1 (de) * 2006-04-08 2007-10-10 Roche Diagnostics GmbH Ortsaufgelöste Analyse optischer Daten eines Testelementes
PL2244086T3 (pl) 2006-04-08 2021-11-22 F. Hoffmann-La Roche Ag Analiza danych optycznych za pomocą histogramów
US20070259366A1 (en) * 2006-05-03 2007-11-08 Greg Lawrence Direct printing of patterned hydrophobic wells
US20080047969A1 (en) * 2006-08-22 2008-02-28 Farhan Fariborz M Method for detecting pill removals from pre-sorted medicine array packs
BRPI0622185A2 (pt) * 2006-11-29 2011-12-27 Celsius S A Lab mÉtodo para a aquisiÇço de uma imagem digital de um resultado de aglutinaÇço, mÉtodo para a anÁlise de um ensaio de aglutinaÇço, mÉtodo para a extraÇço de um conjunto de caracterÍsticas, mÉtodo para a obtenÇço de uma funÇço de quantificaÇço f para uma diluiÇço, mÉtodo para a extraÇço de um resultado quantitativo para cada diluiÇço de uma amostra, mÉtodo para a avaliaÇço de um ensaio de aglutinaÇço e obtenÇço de um resultado semi-quantitativo
US7522282B2 (en) * 2006-11-30 2009-04-21 Purdue Research Foundation Molecular interferometric imaging process and apparatus
US20080144899A1 (en) * 2006-11-30 2008-06-19 Manoj Varma Process for extracting periodic features from images by template matching
US20080230605A1 (en) * 2006-11-30 2008-09-25 Brian Weichel Process and apparatus for maintaining data integrity
EP1936362B1 (de) * 2006-12-20 2020-03-18 Roche Diabetes Care GmbH Testelement mit Referenzierung
US7659968B2 (en) * 2007-01-19 2010-02-09 Purdue Research Foundation System with extended range of molecular sensing through integrated multi-modal data acquisition
JP4528336B2 (ja) * 2007-03-10 2010-08-18 ローム アンド ハース カンパニー 試験ストリップを読み取る方法
WO2008118934A1 (en) 2007-03-26 2008-10-02 Purdue Research Foundation Method and apparatus for conjugate quadrature interferometric detection of an immunoassay
CN101311726B (zh) * 2007-05-25 2011-09-28 开物科技股份有限公司 检测盘的影像检测方法
US8351674B2 (en) * 2007-05-31 2013-01-08 Battelle Energy Alliance, Llc Image portion identification methods, image parsing methods, image parsing systems, and articles of manufacture
ES2561203T3 (es) * 2007-08-22 2016-02-25 Phadia Ab Método y aparato de lectura
EP2034310A1 (de) * 2007-09-08 2009-03-11 Kaiwood Technology Co. Ltd. Bilderkennungsverfahren für Diagnoseteststreifen
US20100239137A1 (en) * 2007-10-09 2010-09-23 Siemens Healthcare Diagnostics Inc. Two Dimensional Imaging of Reacted Areas On a Reagent
US20100142773A1 (en) * 2008-12-10 2010-06-10 Eun Jong Cha Method and system for accurately measuring very small volume of blood
US20110319742A1 (en) * 2009-09-08 2011-12-29 SensiVida Medical Technologies, Inc. Spatial imaging methods for biomedical monitoring and systems thereof
EP2306178A1 (de) 2009-09-30 2011-04-06 Roche Diagnostics GmbH Verfahren zum Steuern einer photometrischen Messeinheit eines Messgeräts zur Gewinnung und Untersuchung einer Körperflüssigkeitsprobe sowie Messsystem
CA2999334C (en) * 2010-07-20 2020-12-15 F. Hoffmann-La Roche Ag Device for detecting an analyte in a bodily fluid
JP5762214B2 (ja) * 2011-08-19 2015-08-12 株式会社Screenホールディングス 電磁波パルス測定装置
CN102590152A (zh) * 2012-03-06 2012-07-18 深圳市汇松科技发展有限公司 一种特定蛋白快速分析仪
WO2013146498A1 (ja) * 2012-03-30 2013-10-03 日本碍子株式会社 微構造解析方法、そのプログラム及び微構造解析装置
WO2014018805A2 (en) 2012-07-25 2014-01-30 Theranos,Inc. Image analysis and measurement of biological samples
US9513224B2 (en) 2013-02-18 2016-12-06 Theranos, Inc. Image analysis and measurement of biological samples
US9528941B2 (en) 2012-08-08 2016-12-27 Scanadu Incorporated Method and apparatus for determining analyte concentration by quantifying and interpreting color information captured in a continuous or periodic manner
WO2014025415A2 (en) 2012-08-08 2014-02-13 Scanadu Incorporated Method and apparatus for performing and quantifying color changes induced by specific concentrations of biological analytes in an automatically calibrated environment
US9285323B2 (en) * 2012-08-08 2016-03-15 Scanadu Incorporated Quantifying color changes of chemical test pads induced concentrations of biological analytes under different lighting conditions
JP6242730B2 (ja) * 2014-03-31 2017-12-06 日本碍子株式会社 微構造解析方法、そのプログラム及び微構造解析装置
TWI591257B (zh) * 2014-05-15 2017-07-11 周文三 空氣壓縮機之旋轉機構
EP3180596A4 (de) 2014-08-15 2018-09-26 Scanadu Incorporated Präzisionsluxmeterverfahren für digitale kameras zur quantifizierung von farben in unkontrollierten beleuchtungsumgebungen
JP6134348B2 (ja) * 2015-03-31 2017-05-24 シスメックス株式会社 細胞撮像装置及び細胞撮像方法
US9689803B1 (en) * 2016-04-20 2017-06-27 Chroma Fish Corp. Method and system for measuring a colorimetric characteristic of a sample and calibration of same
US10768105B1 (en) 2016-07-29 2020-09-08 Labrador Diagnostics Llc Image analysis and measurement of biological samples
WO2019079301A2 (en) 2017-10-18 2019-04-25 Group K Diagnostics, Inc. MONOLAYER MICROFLUIDIC DEVICE AND METHODS OF MAKING AND USING SAME
EP3527972A1 (de) * 2018-02-19 2019-08-21 Roche Diabetes Care GmbH Verfahren und vorrichtungen zur durchführung analytischer messungen
EP3791167A1 (de) * 2018-05-07 2021-03-17 Immundiagnostik AG System zur analyse von quantitativer lateraler durchflusschromatografie
USD879999S1 (en) 2018-11-02 2020-03-31 Group K Diagnostics, Inc. Microfluidic device
CN109298179B (zh) * 2018-11-29 2023-09-01 福州大学 一种免疫层析检测系统及其背景识别方法
DE202023105443U1 (de) 2023-09-19 2023-10-31 Kattempudi Ashok Ein System zur Abbildung einer Probe für biologische oder chemische Analysen

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4020151A (en) * 1976-02-17 1977-04-26 International Diagnostic Technology, Inc. Method for quantitation of antigens or antibodies on a solid surface
US4097845A (en) * 1976-11-01 1978-06-27 Rush-Presbyterian-St. Luke's Medical Center Method of and an apparatus for automatic classification of red blood cells
US4335427A (en) * 1980-04-21 1982-06-15 Technicare Corporation Method of selecting a preferred difference image
US4338024A (en) * 1980-05-02 1982-07-06 International Remote Imaging Systems, Inc. Flow analyzer and system for analysis of fluids with particles
DE3170135D1 (en) * 1980-09-02 1985-05-30 Fuji Photo Film Co Ltd Method for immunochemical measurement of trace components
US4476231A (en) * 1981-07-22 1984-10-09 International Remote Imaging Systems, Inc. Method of analyzing the distribution of a reagent between particles and liquid in a suspension
JPS58130030A (ja) * 1981-10-05 1983-08-03 工業技術院長 X線ディジタル画像処理装置
DE3378933D1 (en) * 1982-10-07 1989-02-16 Toshiba Kk Image data processing apparatus
US4537861A (en) * 1983-02-03 1985-08-27 Elings Virgil B Apparatus and method for homogeneous immunoassay
AU565874B2 (en) * 1983-03-11 1987-10-01 Ei Solutions, Inc. Adaptive threshold circuit for digital image processing
JPS59214431A (ja) * 1983-05-20 1984-12-04 株式会社東芝 放射線診断装置
US4667335A (en) * 1983-06-20 1987-05-19 International Remote Imaging Systems, Inc. Method of determining the diagnostic significance of the content of a volume of biological sample containing particles
US4563701A (en) * 1983-11-14 1986-01-07 Elscint Ltd. Digital diagnostic imaging system
JPS60150729A (ja) * 1984-01-19 1985-08-08 株式会社東芝 X線診断装置
US4647531A (en) * 1984-02-06 1987-03-03 Ortho Diagnostic Systems, Inc. Generalized cytometry instrument and methods of use
US4647544A (en) * 1984-06-25 1987-03-03 Nicoli David F Immunoassay using optical interference detection
JPS6116371A (ja) * 1984-07-03 1986-01-24 Toshiba Corp デジタルフルオログラフイ装置
US4817123A (en) * 1984-09-21 1989-03-28 Picker International Digital radiography detector resolution improvement
US4648053A (en) * 1984-10-30 1987-03-03 Kollmorgen Technologies, Corp. High speed optical inspection system
EP0194132A3 (de) 1985-03-06 1988-08-03 Murex Corporation Abbildendes Immunoprobe-Nachweissystem und Verfahren
JPH0629852B2 (ja) * 1985-08-26 1994-04-20 富士写真フイルム株式会社 偏倚乾式分析要素を用いた液体試料中の被検物質の定量分析方法
US4769776A (en) * 1985-08-30 1988-09-06 Hitachi, Ltd. Apparatus for measuring the concentration of filamentous microorganisms in a mixture including microorganisms
US4737464A (en) * 1985-09-26 1988-04-12 Molecular Devices Corporation Solid-state optical assay imaging apparatus
US5008185A (en) * 1985-11-04 1991-04-16 Cell Analysis Systems, Inc. Methods and apparatus for the quantitation of nuclear proteins
US4741043B1 (en) * 1985-11-04 1994-08-09 Cell Analysis Systems Inc Method of and apparatus for image analyses of biological specimens
US5485527A (en) * 1985-11-04 1996-01-16 Becton Dickinson And Company Apparatus and method for analyses of biological specimens
JPH0652263B2 (ja) * 1985-12-10 1994-07-06 株式会社日立製作所 細胞分析装置
US4891757A (en) * 1986-04-14 1990-01-02 Picker International, Inc. Medical imaging system and method having gray scale mapping means for indicating image saturation regions
US4935346A (en) * 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US4855930A (en) * 1987-03-27 1989-08-08 Chimerix Corporation Method and appartatus for improved time-resolved fluorescence spectroscopy
JP2502591B2 (ja) * 1987-05-13 1996-05-29 株式会社リコー 原稿位置検出装置
JPS6435347A (en) * 1987-07-31 1989-02-06 Sumitomo Electric Industries Detection of intrusion of various bacteria
US4922915A (en) * 1987-11-27 1990-05-08 Ben A. Arnold Automated image detail localization method
US4882492A (en) * 1988-01-19 1989-11-21 Biotronics Associates, Inc. Non-invasive near infrared measurement of blood analyte concentrations
US5121338A (en) * 1988-03-10 1992-06-09 Indiana University Foundation Method for detecting subpopulations in spectral analysis
US5014216A (en) * 1988-07-19 1991-05-07 Beckman Instruments, Inc. Concentration determination with multiple wavelength flash photometers
US5235522A (en) * 1990-10-10 1993-08-10 Cell Analysis Systems, Inc. Method and apparatus for automated analysis of biological specimens
CA2077781A1 (en) * 1991-09-23 1993-03-24 James W. Bacus Method and apparatus for automated assay of biological specimens
ES2150985T3 (es) * 1993-02-26 2000-12-16 E Y Lab Inc Procedimiento y sistema de analisis optico de muestras.

Also Published As

Publication number Publication date
US5717778A (en) 1998-02-10
ES2150985T3 (es) 2000-12-16
JPH08504950A (ja) 1996-05-28
EP0731951A4 (de) 1997-09-17
EP0731951B1 (de) 2000-07-05
WO1994019767A1 (en) 1994-09-01
HK1014598A1 (en) 1999-09-30
EP0731951A1 (de) 1996-09-18
ATE194431T1 (de) 2000-07-15
DE69425158T2 (de) 2001-03-15
JP3093270B2 (ja) 2000-10-03
DK0731951T3 (da) 2000-11-06
US6249593B1 (en) 2001-06-19

Similar Documents

Publication Publication Date Title
DE69425158D1 (de) Optisches probe-analysesystem und verfahren
BR9611461A (pt) Aparelho de coleta de amostras, kit para a detecçao de um analisado em uma amostra, uso do aparelho de coleta de amostra e do kit e processo para detectar um analisado em uma amostra.
NZ306051A (en) Testing using electrochemiluminescence
ATE514072T1 (de) Verfahren zur bestimmung von teilchen in einer flüssigen probe
DE69934506D1 (de) Vorrichtung und verfahren zur automatischen analyse von proben
MY107650A (en) Method of estimating property and / or composition data of a test sample
DE69718092D1 (de) Kontrolllösung und Verfahren um die Leistung einer elektrochemischen Vorrichtung zur Bestimmung der Konzentration eines Analyten im Blut zu testen
DE69519160D1 (de) Verfahren zur quantitativen analyse von cholesterin
CA2380027A1 (en) Apparatus and method for detecting, quantifying and characterizing microorganisms
ATE246378T1 (de) Verfahren zum feststellen der preparationsgüte von objektträgern und proben
SE9602545L (sv) Metod för att diskriminera komplexa biologiska prover
ATE194710T1 (de) Verfahren und vorrichtung zur zählung und klassifizierung von zellen
ATA114789A (de) Verfahren und vorrichtung zur feststellung biologischer aktivitaeten in einer probe
DE60121446D1 (de) Kelvin-rastermikroprobensystem und verfahren zur oberflächenanalyse
GB2280754A (en) Electrochemical detection of DNA hybridisation
AU547916B2 (en) Wipe-off test device
CN106645706A (zh) 一种移动终端定量分析胶体金检测试剂的方法
US20100221765A1 (en) Microtube reader device for the analysis of blood samples
ATE543093T1 (de) Analysegerät für ein grossflächiges bild
CN106226291A (zh) 一种移动终端定量分析干化学检测试剂的方法
ATE153764T1 (de) Vorrichtung und verfahren zur durchführung biologischer assays, die ein partikelsiebsystem enthalten
Britton Standardizing and implementing good laboratory practices
DE60317497D1 (de) Verfahren, system und kit zum nachweis eines analyten in einer probe
Ludwig et al. Video analysis of DNA sequence homologs
ATE184109T1 (de) Indikatorreagenzien zum nachweis oder zur messung von analyten, testsatz, der diese enthält, und verfahren zum nachweis oder zur messung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition