DE69423990T2 - Tabletten mit verbesserter Verschleissfestigkeit und Verfahren zu ihrer Herstellung - Google Patents

Tabletten mit verbesserter Verschleissfestigkeit und Verfahren zu ihrer Herstellung

Info

Publication number
DE69423990T2
DE69423990T2 DE69423990T DE69423990T DE69423990T2 DE 69423990 T2 DE69423990 T2 DE 69423990T2 DE 69423990 T DE69423990 T DE 69423990T DE 69423990 T DE69423990 T DE 69423990T DE 69423990 T2 DE69423990 T2 DE 69423990T2
Authority
DE
Germany
Prior art keywords
oily
fatty substance
uncoated tablet
weight
uncoated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69423990T
Other languages
German (de)
English (en)
Other versions
DE69423990D1 (de
Inventor
Junichi Kikuta
Hiroyoshi Koyama
Hiroshi Matoba
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69423990D1 publication Critical patent/DE69423990D1/de
Publication of DE69423990T2 publication Critical patent/DE69423990T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2210/00—Fluid
    • F04C2210/26—Refrigerants with particular properties, e.g. HFC-134a

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69423990T 1993-02-10 1994-02-07 Tabletten mit verbesserter Verschleissfestigkeit und Verfahren zu ihrer Herstellung Expired - Lifetime DE69423990T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4595893 1993-02-10

Publications (2)

Publication Number Publication Date
DE69423990D1 DE69423990D1 (de) 2000-05-25
DE69423990T2 true DE69423990T2 (de) 2000-08-17

Family

ID=12733779

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69423990T Expired - Lifetime DE69423990T2 (de) 1993-02-10 1994-02-07 Tabletten mit verbesserter Verschleissfestigkeit und Verfahren zu ihrer Herstellung

Country Status (10)

Country Link
US (1) US5456920A (OSRAM)
EP (1) EP0610854B1 (OSRAM)
KR (1) KR940019294A (OSRAM)
CN (1) CN1106652A (OSRAM)
AT (1) ATE191846T1 (OSRAM)
CA (1) CA2115308C (OSRAM)
DE (1) DE69423990T2 (OSRAM)
FI (1) FI940585A7 (OSRAM)
NO (1) NO940373L (OSRAM)
TW (1) TW272942B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005028696A1 (de) * 2005-06-21 2006-12-28 Pulmotec Gmbh Verwendung eines Hilfsstoffs zur Einstellung der Abrasionsfestigkeit eines verfestigten Wirkstoffpräparats

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0553777B1 (en) * 1992-01-29 2002-04-24 Takeda Chemical Industries, Ltd. Fast dissolving tablet and its production
TW466119B (en) * 1994-02-28 2001-12-01 Janssen Pharmaceutica Nv Film coated tablet of paracetamol and domperidone
GB9421836D0 (en) * 1994-10-28 1994-12-14 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
CN1220598A (zh) * 1996-05-02 1999-06-23 大正制药株式会社 水难溶性酸性药物的悬浮液
TW592727B (en) 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
WO1999026606A2 (en) * 1997-11-25 1999-06-03 Bayer Aktiengesellschaft SUSTAINED RELEASE FORMULATIONS COMPRISING α-GLUCOSIDASE-INHIBITORS
AU3601899A (en) * 1998-03-31 1999-10-18 Bayer Aktiengesellschaft Valiolone, a method of preparing it, and its use to prepare acarbose and voglibose
CH689452C1 (de) * 1998-04-15 2004-11-30 Marcel Christian Wegmueller Verfahren zur Verhinderung von zementbedingten ablagerungen in einem Bauwerksentwaesserungssystem.
CA2359244C (en) 1999-01-13 2013-10-08 Bayer Healthcare Llc .omega.-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
EP1027886B1 (en) * 1999-02-10 2008-07-09 Pfizer Products Inc. Pharmaceutical solid dispersions
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
JP4980527B2 (ja) * 1999-06-07 2012-07-18 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 酸に不安定な活性化合物を含有する新規の製剤および投与形
BR0013719A (pt) 1999-09-02 2002-07-23 Nostrum Pharmaceuticals Inc Dosagem oral de liberaçâo controlada, apropriada para administração oral
US20100196466A1 (en) * 2000-06-06 2010-08-05 Capricorn Pharma Inc. Drug delivery system
US20070059367A1 (en) * 2000-06-06 2007-03-15 Cherukuri S R Drug Delivery System and Associated Methods
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
US7052706B2 (en) * 2001-06-08 2006-05-30 Nostrum Pharmaceuticals, Inc. Control release formulation containing a hydrophobic material as the sustained release agent
US6660292B2 (en) * 2001-06-19 2003-12-09 Hf Flavoring Technology Llp Rapidly disintegrating flavored film for precooked foods
US6982094B2 (en) 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US7323192B2 (en) * 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
CA2447984A1 (en) 2001-09-28 2003-04-03 Mcneil-Ppc, Inc. Dosage forms having an inner core and outer shell with different shapes
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
EP2324825A1 (en) 2002-02-11 2011-05-25 Bayer Healthcare LLC Aryl ureas with angiogenesis inhibiting activity
US7011688B2 (en) * 2002-05-10 2006-03-14 C.R. Bard, Inc. Prosthetic repair fabric
US20040116532A1 (en) * 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
US7807197B2 (en) * 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
UY28213A1 (es) 2003-02-28 2004-09-30 Bayer Pharmaceuticals Corp Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos.
ATE445393T1 (de) * 2003-04-24 2009-10-15 Jagotec Ag Tablette mit gefärbtem kern
DE602004007382T2 (de) 2003-05-20 2008-04-17 Bayer Pharmaceuticals Corp., West Haven Diaryl-harnstoffe für durch pdgfr vermittelte krankheiten
DK1663978T3 (da) 2003-07-23 2008-04-07 Bayer Pharmaceuticals Corp Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser
FR2862187B1 (fr) * 2003-11-19 2006-02-24 Sbm Dev Nouvelles compositions agrochimiques et leur procede de fabrication
FR2867025B1 (fr) * 2004-03-05 2006-06-02 Sbm Dev Compositions agrochimiques solides a desagregation rapide
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
SG174026A1 (en) 2006-08-03 2011-09-29 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
TW200829286A (en) * 2006-09-06 2008-07-16 Genzyme Corp Polystyrene sulfonate polymer tablets, their preparation and use
EP2076249A2 (en) * 2006-10-27 2009-07-08 FMC Corporation Dry granulation binders, products, and use thereof
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
US20110136815A1 (en) 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
AU2019288476A1 (en) 2018-06-21 2021-03-18 Aquestive Therapeutics, Inc. System and method for making personalized individual unit doses containing pharmaceutical actives
CN117695238A (zh) * 2023-12-19 2024-03-15 新美誉(杭州)生物科技有限公司 一种盐酸曲唑酮缓释片及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0070127A3 (en) * 1981-07-10 1983-08-17 Beecham Group Plc Tablets
JPH01308231A (ja) * 1988-06-03 1989-12-12 Takeda Chem Ind Ltd 安定化された医薬組成物および製造法
JPH0425926A (ja) * 1990-05-22 1992-01-29 Toshiba Corp 情報処理装置
TW284688B (OSRAM) * 1991-11-20 1996-09-01 Takeda Pharm Industry Co Ltd

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005028696A1 (de) * 2005-06-21 2006-12-28 Pulmotec Gmbh Verwendung eines Hilfsstoffs zur Einstellung der Abrasionsfestigkeit eines verfestigten Wirkstoffpräparats

Also Published As

Publication number Publication date
CA2115308A1 (en) 1994-08-11
KR940019294A (ko) 1994-09-14
EP0610854B1 (en) 2000-04-19
US5456920A (en) 1995-10-10
FI940585L (fi) 1994-08-11
CA2115308C (en) 2004-05-11
FI940585A0 (fi) 1994-02-09
DE69423990D1 (de) 2000-05-25
TW272942B (OSRAM) 1996-03-21
NO940373L (no) 1994-08-11
ATE191846T1 (de) 2000-05-15
FI940585A7 (fi) 1994-08-11
CN1106652A (zh) 1995-08-16
NO940373D0 (no) 1994-02-04
EP0610854A1 (en) 1994-08-17

Similar Documents

Publication Publication Date Title
US5456920A (en) Uncoated tablets and method of producing the same
DE69322077T2 (de) Auf hydroxyethylzellulose basierende oralen arzneidosisformen mit verzoegerter wirkstoffabgabe
DE69432015T2 (de) Verfahren
DE69427466T2 (de) Bisacodyl dosierungsform
DE69802543T3 (de) Verbesserte multipartikel-tablette mit schnellauflösbarkeit
DE69434479T2 (de) Tramadolhaltiges Arzneimittel mit gesteuerter Wirkstoffabgabe
DE69727153T2 (de) Im magen verweilende orale arzneistoffdosisformen zur gesteuerten freisetzung schwerlöslicher arzneistoffe und unlöslicher stoffe
DE69820287T2 (de) Pharmazeutische Zubereitung, die Chlodronat als Wirkstoff und silicifizierte mikrokristalline Cellulose als Exipienten umfasst
DE3880762T2 (de) Orale, acetaminophen enthaltende zusammensetzung mit gesteuerter arzneistoff-freisetzung und verfahren zu ihrer herstellung.
DE69434640T2 (de) Heterodisperse Hydrogelsysteme zur verzögerten Freisetzung unlöslicher Arzneistoffe
US4882167A (en) Dry direct compression compositions for controlled release dosage forms
DE69828595T2 (de) Gastrointestinale an der mucosa haftende pharmazeutische zusammensetzung
DE60221691T2 (de) Tamsulosin tabletten ohne nahrungsmitteleffekt
DE69838300T2 (de) Pharmazeutische suspensionstabletten-zusammenstellungen
EP1509205B1 (de) Pharmazeutische zusammensetzung mit verzögerter wirkstofffreisetzung und verfahren zu deren zubereitung
DE29825080U1 (de) Pharmazeutische Fenofibratzusammensetzung mit erhöhter Bioverfügbarkeit
DD223360A5 (de) Neue galenische zubereitungsformen von oralen antidiabetika und verfahren zu ihrer herstellung
DD292837A5 (de) Verfahren zur herstellung von cholestyramin-tabletten
CH665124A5 (de) Verfahren zur herstellung von tabletten mit regulierter wirkstoffabgabe.
DE60036014T2 (de) Methode zur stabilisierung von benzimidazol-verbindungen
EP0250648B1 (de) Pharmazeutisches Präparat zur verzögerten Freigabe von Ibuprofen
DE60211183T2 (de) Pharmazeutische zusammensetzung enthaltend lumiracoxib
DE60320661T2 (de) System mit kontrollierter freisetzung bioaktiver wirkstoffe
DE60103247T2 (de) Verfahren zur Herstellung von Formulierungen zur Direkttablettierung
DE3936112A1 (de) Arzneimittelpraeparate und verfahren zu deren herstellung

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP