CA2115308C - Uncoated tablets and method of producing the same - Google Patents

Uncoated tablets and method of producing the same Download PDF

Info

Publication number
CA2115308C
CA2115308C CA002115308A CA2115308A CA2115308C CA 2115308 C CA2115308 C CA 2115308C CA 002115308 A CA002115308 A CA 002115308A CA 2115308 A CA2115308 A CA 2115308A CA 2115308 C CA2115308 C CA 2115308C
Authority
CA
Canada
Prior art keywords
weight
tablet
oily
compression
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002115308A
Other languages
English (en)
French (fr)
Other versions
CA2115308A1 (en
Inventor
Hiroshi Matoba
Hiroyoshi Koyama
Junichi Kikuta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of CA2115308A1 publication Critical patent/CA2115308A1/en
Application granted granted Critical
Publication of CA2115308C publication Critical patent/CA2115308C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2210/00—Fluid
    • F04C2210/26—Refrigerants with particular properties, e.g. HFC-134a

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002115308A 1993-02-10 1994-02-09 Uncoated tablets and method of producing the same Expired - Fee Related CA2115308C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP45958/1993 1993-02-10
JP4595893 1993-02-10

Publications (2)

Publication Number Publication Date
CA2115308A1 CA2115308A1 (en) 1994-08-11
CA2115308C true CA2115308C (en) 2004-05-11

Family

ID=12733779

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002115308A Expired - Fee Related CA2115308C (en) 1993-02-10 1994-02-09 Uncoated tablets and method of producing the same

Country Status (10)

Country Link
US (1) US5456920A (OSRAM)
EP (1) EP0610854B1 (OSRAM)
KR (1) KR940019294A (OSRAM)
CN (1) CN1106652A (OSRAM)
AT (1) ATE191846T1 (OSRAM)
CA (1) CA2115308C (OSRAM)
DE (1) DE69423990T2 (OSRAM)
FI (1) FI940585A7 (OSRAM)
NO (1) NO940373L (OSRAM)
TW (1) TW272942B (OSRAM)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3069458B2 (ja) * 1992-01-29 2000-07-24 武田薬品工業株式会社 口腔内崩壊型錠剤およびその製造法
TW466119B (en) * 1994-02-28 2001-12-01 Janssen Pharmaceutica Nv Film coated tablet of paracetamol and domperidone
GB9421836D0 (en) * 1994-10-28 1994-12-14 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
KR20000010696A (ko) * 1996-05-02 2000-02-25 우에하라 아끼라 수 난용성 산성 약물의 현탁액제
TW592727B (en) 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
AU1234399A (en) * 1997-11-25 1999-06-15 Bayer Aktiengesellschaft Sustained release formulations comprising alpha-glucosidase-i nhibitors
AU3601899A (en) * 1998-03-31 1999-10-18 Bayer Aktiengesellschaft Valiolone, a method of preparing it, and its use to prepare acarbose and voglibose
CH689452C1 (de) * 1998-04-15 2004-11-30 Marcel Christian Wegmueller Verfahren zur Verhinderung von zementbedingten ablagerungen in einem Bauwerksentwaesserungssystem.
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
ATE538794T1 (de) 1999-01-13 2012-01-15 Bayer Healthcare Llc Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
ES2307482T3 (es) * 1999-02-10 2008-12-01 Pfizer Products Inc. Dispersiones farmaceuticas solidas.
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
CA2376202C (en) * 1999-06-07 2008-11-18 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel preparation and administration form comprising an acid-labile active compound
AU783656B2 (en) 1999-09-02 2005-11-24 Nostrum Pharmaceuticals, Inc. Controlled release oral dosage suitable for oral administration
US20100196466A1 (en) * 2000-06-06 2010-08-05 Capricorn Pharma Inc. Drug delivery system
US20070059367A1 (en) * 2000-06-06 2007-03-15 Cherukuri S R Drug Delivery System and Associated Methods
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
US7052706B2 (en) * 2001-06-08 2006-05-30 Nostrum Pharmaceuticals, Inc. Control release formulation containing a hydrophobic material as the sustained release agent
US6660292B2 (en) * 2001-06-19 2003-12-09 Hf Flavoring Technology Llp Rapidly disintegrating flavored film for precooked foods
US7323192B2 (en) * 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US6982094B2 (en) 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US20040241236A1 (en) * 2001-09-28 2004-12-02 Shun-Por Li Modified release dosage forms
DK1478358T3 (da) 2002-02-11 2013-10-07 Bayer Healthcare Llc Sorafenibtosylat til behandling af sygdomme kendetegnet ved unormal angiogenese
US7011688B2 (en) * 2002-05-10 2006-03-14 C.R. Bard, Inc. Prosthetic repair fabric
US20040116532A1 (en) 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
US7807197B2 (en) * 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US7557129B2 (en) 2003-02-28 2009-07-07 Bayer Healthcare Llc Cyanopyridine derivatives useful in the treatment of cancer and other disorders
ES2335008T3 (es) * 2003-04-24 2010-03-18 Jagotec Ag Comprimido con nucleo coloreado.
US20070020704A1 (en) 2003-05-20 2007-01-25 Scott Wilhelm Diaryl ureas with kinase inhibiting activity
US8637553B2 (en) 2003-07-23 2014-01-28 Bayer Healthcare Llc Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
FR2862187B1 (fr) * 2003-11-19 2006-02-24 Sbm Dev Nouvelles compositions agrochimiques et leur procede de fabrication
FR2867025B1 (fr) * 2004-03-05 2006-06-02 Sbm Dev Compositions agrochimiques solides a desagregation rapide
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
DE102005028696A1 (de) * 2005-06-21 2006-12-28 Pulmotec Gmbh Verwendung eines Hilfsstoffs zur Einstellung der Abrasionsfestigkeit eines verfestigten Wirkstoffpräparats
EP2049123B2 (en) 2006-08-03 2016-08-24 Horizon Pharma AG Delayed-release glucocorticoid treatment of rheumatoid disease
TW200829286A (en) * 2006-09-06 2008-07-16 Genzyme Corp Polystyrene sulfonate polymer tablets, their preparation and use
JP2010507676A (ja) * 2006-10-27 2010-03-11 エフ エム シー コーポレーション 乾式顆粒化結合剤、生成物およびその使用
US20110136815A1 (en) 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
EP3811371A1 (en) 2018-06-21 2021-04-28 Aquestive Therapeutics, Inc. System and method for making personalized individual unit doses containing pharmaceutical actives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0070127A3 (en) * 1981-07-10 1983-08-17 Beecham Group Plc Tablets
JPH01308231A (ja) * 1988-06-03 1989-12-12 Takeda Chem Ind Ltd 安定化された医薬組成物および製造法
JPH0425926A (ja) * 1990-05-22 1992-01-29 Toshiba Corp 情報処理装置
TW284688B (OSRAM) * 1991-11-20 1996-09-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
FI940585A0 (fi) 1994-02-09
NO940373D0 (no) 1994-02-04
DE69423990D1 (de) 2000-05-25
EP0610854B1 (en) 2000-04-19
TW272942B (OSRAM) 1996-03-21
DE69423990T2 (de) 2000-08-17
CN1106652A (zh) 1995-08-16
US5456920A (en) 1995-10-10
ATE191846T1 (de) 2000-05-15
CA2115308A1 (en) 1994-08-11
FI940585L (fi) 1994-08-11
KR940019294A (ko) 1994-09-14
EP0610854A1 (en) 1994-08-17
FI940585A7 (fi) 1994-08-11
NO940373L (no) 1994-08-11

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