ATE191846T1 - Tabletten mit verbesserter verschleissfestigkeit und verfahren zu ihrer herstellung - Google Patents

Tabletten mit verbesserter verschleissfestigkeit und verfahren zu ihrer herstellung

Info

Publication number
ATE191846T1
ATE191846T1 AT94101809T AT94101809T ATE191846T1 AT E191846 T1 ATE191846 T1 AT E191846T1 AT 94101809 T AT94101809 T AT 94101809T AT 94101809 T AT94101809 T AT 94101809T AT E191846 T1 ATE191846 T1 AT E191846T1
Authority
AT
Austria
Prior art keywords
oily
fatty substance
excipient
compression
active ingredient
Prior art date
Application number
AT94101809T
Other languages
German (de)
English (en)
Inventor
Hiroshi Matoba
Hiroyoshi Koyama
Junichi Kikuta
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE191846T1 publication Critical patent/ATE191846T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2210/00—Fluid
    • F04C2210/26—Refrigerants with particular properties, e.g. HFC-134a

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT94101809T 1993-02-10 1994-02-07 Tabletten mit verbesserter verschleissfestigkeit und verfahren zu ihrer herstellung ATE191846T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4595893 1993-02-10

Publications (1)

Publication Number Publication Date
ATE191846T1 true ATE191846T1 (de) 2000-05-15

Family

ID=12733779

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94101809T ATE191846T1 (de) 1993-02-10 1994-02-07 Tabletten mit verbesserter verschleissfestigkeit und verfahren zu ihrer herstellung

Country Status (10)

Country Link
US (1) US5456920A (OSRAM)
EP (1) EP0610854B1 (OSRAM)
KR (1) KR940019294A (OSRAM)
CN (1) CN1106652A (OSRAM)
AT (1) ATE191846T1 (OSRAM)
CA (1) CA2115308C (OSRAM)
DE (1) DE69423990T2 (OSRAM)
FI (1) FI940585A7 (OSRAM)
NO (1) NO940373L (OSRAM)
TW (1) TW272942B (OSRAM)

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JP3069458B2 (ja) * 1992-01-29 2000-07-24 武田薬品工業株式会社 口腔内崩壊型錠剤およびその製造法
TW466119B (en) * 1994-02-28 2001-12-01 Janssen Pharmaceutica Nv Film coated tablet of paracetamol and domperidone
GB9421836D0 (en) * 1994-10-28 1994-12-14 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
KR20000010696A (ko) * 1996-05-02 2000-02-25 우에하라 아끼라 수 난용성 산성 약물의 현탁액제
TW592727B (en) 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
WO1999026606A2 (en) * 1997-11-25 1999-06-03 Bayer Aktiengesellschaft SUSTAINED RELEASE FORMULATIONS COMPRISING α-GLUCOSIDASE-INHIBITORS
WO1999050217A1 (en) * 1998-03-31 1999-10-07 Bayer Aktiengesellschaft Valiolone, a method of preparing it, and its use to prepare acarbose and voglibose
CH689452C1 (de) * 1998-04-15 2004-11-30 Marcel Christian Wegmueller Verfahren zur Verhinderung von zementbedingten ablagerungen in einem Bauwerksentwaesserungssystem.
JP2002534468A (ja) 1999-01-13 2002-10-15 バイエル コーポレイション ｐ３８キナーゼ阻害剤としてのω−カルボキシアリール置換ジフェニル尿素
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
DE60039379D1 (de) * 1999-02-10 2008-08-21 Pfizer Prod Inc Pharmazeutische feste Dispersionen
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
EP1616562A1 (en) * 1999-06-07 2006-01-18 ALTANA Pharma AG Novel preparation and administration form comprising an acid-labile active compound
JP2003508420A (ja) 1999-09-02 2003-03-04 ノストラム・ファーマスーティカルズ・インコーポレイテッド 経口投与に適した、制御された放出の経口用量
US20100196466A1 (en) * 2000-06-06 2010-08-05 Capricorn Pharma Inc. Drug delivery system
US20070059367A1 (en) * 2000-06-06 2007-03-15 Cherukuri S R Drug Delivery System and Associated Methods
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
US7052706B2 (en) * 2001-06-08 2006-05-30 Nostrum Pharmaceuticals, Inc. Control release formulation containing a hydrophobic material as the sustained release agent
US6660292B2 (en) * 2001-06-19 2003-12-09 Hf Flavoring Technology Llp Rapidly disintegrating flavored film for precooked foods
CA2461653A1 (en) * 2001-09-28 2003-04-03 Mcneil-Ppc, Inc. Edible composition and dosage form comprising an edible shell
US7323192B2 (en) * 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US6982094B2 (en) 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
PT1478358E (pt) 2002-02-11 2013-09-11 Bayer Healthcare Llc Tosilato de sorafenib para o tratamento de doenças caracterizadas por angiogénese anormal
US7011688B2 (en) * 2002-05-10 2006-03-14 C.R. Bard, Inc. Prosthetic repair fabric
US20040116532A1 (en) 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
US7807197B2 (en) * 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
UY28213A1 (es) 2003-02-28 2004-09-30 Bayer Pharmaceuticals Corp Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos.
ATE445393T1 (de) * 2003-04-24 2009-10-15 Jagotec Ag Tablette mit gefärbtem kern
DK1636585T3 (da) 2003-05-20 2008-05-26 Bayer Pharmaceuticals Corp Diarylurinstoffer med kinasehæmmende aktivitet
PT1663978E (pt) 2003-07-23 2008-02-15 Bayer Pharmaceuticals Corp Omega-carboxiaril difenil ureia substituída por flúor para o tratamento e a prevenção de doenças e estados patológicos
FR2862187B1 (fr) * 2003-11-19 2006-02-24 Sbm Dev Nouvelles compositions agrochimiques et leur procede de fabrication
FR2867025B1 (fr) * 2004-03-05 2006-06-02 Sbm Dev Compositions agrochimiques solides a desagregation rapide
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
DE102005028696A1 (de) * 2005-06-21 2006-12-28 Pulmotec Gmbh Verwendung eines Hilfsstoffs zur Einstellung der Abrasionsfestigkeit eines verfestigten Wirkstoffpräparats
EP2049123B2 (en) 2006-08-03 2016-08-24 Horizon Pharma AG Delayed-release glucocorticoid treatment of rheumatoid disease
TW200829286A (en) * 2006-09-06 2008-07-16 Genzyme Corp Polystyrene sulfonate polymer tablets, their preparation and use
US7998505B2 (en) * 2006-10-27 2011-08-16 Fmc Corporation Dry granulation binders, products, and use thereof
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
US20110136815A1 (en) 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
BR112021001738A2 (pt) 2018-06-21 2021-06-29 Aquestive Therapeutics, Inc. sistema e método para fabricação de doses unitárias individuais personalizadas contendo ativos farmacêuticos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0070127A3 (en) * 1981-07-10 1983-08-17 Beecham Group Plc Tablets
JPH01308231A (ja) * 1988-06-03 1989-12-12 Takeda Chem Ind Ltd 安定化された医薬組成物および製造法
JPH0425926A (ja) * 1990-05-22 1992-01-29 Toshiba Corp 情報処理装置
TW284688B (OSRAM) * 1991-11-20 1996-09-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
US5456920A (en) 1995-10-10
EP0610854B1 (en) 2000-04-19
DE69423990D1 (de) 2000-05-25
FI940585L (fi) 1994-08-11
FI940585A7 (fi) 1994-08-11
TW272942B (OSRAM) 1996-03-21
NO940373L (no) 1994-08-11
KR940019294A (ko) 1994-09-14
EP0610854A1 (en) 1994-08-17
DE69423990T2 (de) 2000-08-17
FI940585A0 (fi) 1994-02-09
NO940373D0 (no) 1994-02-04
CN1106652A (zh) 1995-08-16
CA2115308C (en) 2004-05-11
CA2115308A1 (en) 1994-08-11

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Legal Events

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