DE69419461T2 - Vorrichtung zum Auffangen von zielmolekülen und diese Vorrichtung benutzendes Auffangverfahren - Google Patents
Vorrichtung zum Auffangen von zielmolekülen und diese Vorrichtung benutzendes AuffangverfahrenInfo
- Publication number
- DE69419461T2 DE69419461T2 DE69419461T DE69419461T DE69419461T2 DE 69419461 T2 DE69419461 T2 DE 69419461T2 DE 69419461 T DE69419461 T DE 69419461T DE 69419461 T DE69419461 T DE 69419461T DE 69419461 T2 DE69419461 T2 DE 69419461T2
- Authority
- DE
- Germany
- Prior art keywords
- ligand
- polynucleotide
- complex
- target
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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- MXHRCPNRJAMMIM-UHFFFAOYSA-N desoxyuridine Natural products C1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 MXHRCPNRJAMMIM-UHFFFAOYSA-N 0.000 description 1
- 150000001993 dienes Chemical class 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- 229910000397 disodium phosphate Inorganic materials 0.000 description 1
- 235000019800 disodium phosphate Nutrition 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
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- 239000011521 glass Substances 0.000 description 1
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- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
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- 229910052739 hydrogen Inorganic materials 0.000 description 1
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- 229960003786 inosine Drugs 0.000 description 1
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- 238000011835 investigation Methods 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 239000006249 magnetic particle Substances 0.000 description 1
- 229960003151 mercaptamine Drugs 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 150000002825 nitriles Chemical group 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- 238000010526 radical polymerization reaction Methods 0.000 description 1
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- 230000002285 radioactive effect Effects 0.000 description 1
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- 229920005989 resin Polymers 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 239000002336 ribonucleotide Substances 0.000 description 1
- 125000002652 ribonucleotide group Chemical group 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- UIIMBOGNXHQVGW-UHFFFAOYSA-M sodium bicarbonate Substances [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 150000003440 styrenes Chemical class 0.000 description 1
- JJAHTWIKCUJRDK-UHFFFAOYSA-N succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate Chemical compound C1CC(CN2C(C=CC2=O)=O)CCC1C(=O)ON1C(=O)CCC1=O JJAHTWIKCUJRDK-UHFFFAOYSA-N 0.000 description 1
- 235000011149 sulphuric acid Nutrition 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 238000006276 transfer reaction Methods 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 229920003176 water-insoluble polymer Polymers 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9307797A FR2707010B1 (enExample) | 1993-06-25 | 1993-06-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69419461D1 DE69419461D1 (de) | 1999-08-19 |
| DE69419461T2 true DE69419461T2 (de) | 2000-04-13 |
Family
ID=9448588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69419461T Expired - Fee Related DE69419461T2 (de) | 1993-06-25 | 1994-06-24 | Vorrichtung zum Auffangen von zielmolekülen und diese Vorrichtung benutzendes Auffangverfahren |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5723344A (enExample) |
| EP (1) | EP0632269B1 (enExample) |
| CA (1) | CA2126636C (enExample) |
| DE (1) | DE69419461T2 (enExample) |
| DK (1) | DK0632269T3 (enExample) |
| ES (1) | ES2133507T3 (enExample) |
| FR (1) | FR2707010B1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2706618B1 (fr) * | 1993-06-11 | 1995-09-01 | Bio Merieux | Dispositif pour le dosage d'haptènes et son utilisation. |
| US6893816B1 (en) | 1993-10-28 | 2005-05-17 | Houston Advanced Research Center | Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions |
| FR2758884B1 (fr) * | 1997-01-30 | 1999-04-02 | Bio Merieux | Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu |
| DE69835516D1 (de) * | 1997-05-16 | 2006-09-21 | Exact Sciences Corp | Elektrophoretische analyse von molekülen mit immobilisierten sonden |
| FR2764988B1 (fr) * | 1997-06-20 | 1999-07-23 | Bio Merieux | Compose conjugue, reactif et kit le contenant, et utilisations dans un procede de fixation d'un materiel biologique |
| FR2767137A1 (fr) * | 1997-08-07 | 1999-02-12 | Bio Merieux | Compose chimique complexe, synthese et applications diverses dudit compose |
| FR2768743B1 (fr) | 1997-09-23 | 2001-09-14 | Bio Merieux | Procede de lyse de micro-organisme |
| US6033918A (en) * | 1997-11-10 | 2000-03-07 | Bayer Corporation | Method and device for the detection of analyte in a fluid sample |
| US6303325B1 (en) | 1998-05-29 | 2001-10-16 | Dade Behring Inc. | Method for detecting analytes |
| US6664045B1 (en) * | 1998-06-18 | 2003-12-16 | Boston Probes, Inc. | PNA probes, probe sets, methods and kits pertaining to the detection of microorganisms |
| AU762049B2 (en) * | 1998-06-19 | 2003-06-19 | Exact Sciences Corporation | Detection of non-viral organisms with SRP RNA |
| US6743585B2 (en) | 1999-09-16 | 2004-06-01 | Agilent Technologies, Inc. | Methods for preparing conjugates |
| DE60044030D1 (de) * | 1999-10-08 | 2010-04-29 | Robert C Leif | Markerkomplexe aus konjugierten polymeren |
| FR2804117B1 (fr) * | 2000-01-21 | 2004-08-20 | Bio Merieux | Procede d'isolement de proteines et/ou d'acides nucleiques, complexes de particules et de proteines et/ou d'acides nucleiques, reactif et applications |
| US20040091451A1 (en) * | 2000-05-29 | 2004-05-13 | Marie-Therese Charreyre | Biocompatible polymer for fixing biological ligands |
| FR2811321A1 (fr) * | 2000-07-04 | 2002-01-11 | Bio Merieux | Amplificateur d'une region ribonucleique cible d'un arn ribosomal 16s ou adn pour un tel arn d'une espece eubacterienne et detection de telles especes |
| CN1174011C (zh) * | 2000-07-28 | 2004-11-03 | 大日本油墨化学工业株式会社 | 吸水性材料及使用其的吸收性物品 |
| AU2001284092A1 (en) * | 2000-07-31 | 2002-02-13 | Bio Merieux | Succinimide derivative useful as polymerisable bifunctional monomer |
| FR2817968B1 (fr) * | 2000-12-07 | 2003-03-21 | Bio Merieux | Dispositif de capture d'une molecule cible |
| NZ511705A (en) * | 2001-05-14 | 2004-03-26 | Horticulture & Food Res Inst | Methods and rapid immunoassay device for detecting progesterone and other steroids |
| US20030087309A1 (en) * | 2001-08-27 | 2003-05-08 | Shiping Chen | Desktop drug screening system |
| US10539561B1 (en) * | 2001-08-30 | 2020-01-21 | Customarray, Inc. | Enzyme-amplified redox microarray detection process |
| US20030124599A1 (en) * | 2001-11-14 | 2003-07-03 | Shiping Chen | Biochemical analysis system with combinatorial chemistry applications |
| FR2832508A1 (fr) * | 2001-11-21 | 2003-05-23 | Bio Merieux | Procede d'obtention d'une phase de capture et d'une phase de detection d'un materiel biologique cible et utilisation dans des tests elisa |
| AU2003302704A1 (en) * | 2002-12-02 | 2004-06-23 | Toyo Kohan Co., Ltd. | Method of immobilizing polynucleotide on solid support, solid immobilization support thus obtained, method of detecting target polynucleotide from the solid support and solution for immobilizing polynucleotide |
| FR2848556B1 (fr) * | 2002-12-13 | 2006-06-16 | Bio Merieux | Procede de polymerisation radicalaire controlee |
| JP2004313181A (ja) * | 2003-04-02 | 2004-11-11 | Canon Inc | 感染症起炎菌検出用プローブ及びプローブセット、ならびに担体及び遺伝子検査方法 |
| US7316096B2 (en) * | 2004-06-30 | 2008-01-08 | Yale Security Inc. | Door operator |
| US20060102471A1 (en) | 2004-11-18 | 2006-05-18 | Karl Maurer | Electrode array device having an adsorbed porous reaction layer |
| US20070034513A1 (en) | 2005-03-25 | 2007-02-15 | Combimatrix Corporation | Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array |
| US9394167B2 (en) | 2005-04-15 | 2016-07-19 | Customarray, Inc. | Neutralization and containment of redox species produced by circumferential electrodes |
| US20070065877A1 (en) | 2005-09-19 | 2007-03-22 | Combimatrix Corporation | Microarray having a base cleavable succinate linker |
| US8609829B2 (en) | 2005-10-17 | 2013-12-17 | Gen-Probe Incorporated | Compositions and methods to detect Legionella pneumophila nucleic acid |
| EP1937847A2 (en) * | 2005-10-17 | 2008-07-02 | Gen-Probe Incorporated | Compositions and methods to detect legionella pneumophila nucleic acid |
| US20070155907A1 (en) * | 2005-12-30 | 2007-07-05 | Zhao Jonathon Z | Biologically active block copolymers |
| WO2011090793A2 (en) | 2010-01-20 | 2011-07-28 | Customarray, Inc. | Multiplex microarray of serially deposited biomolecules on a microarray |
| WO2011124715A1 (en) * | 2010-04-09 | 2011-10-13 | Marcella Chiari | Silane copolymers and uses thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4070348A (en) * | 1973-07-25 | 1978-01-24 | Rohm Gmbh | Water-swellable, bead copolymer |
| IT1044797B (it) * | 1974-10-15 | 1980-04-21 | Ferruti Paolo | Alti polimeri contenenti radicali prostaglandinici processo per la loro preparazione e loro impiego |
| US4478914B1 (en) * | 1980-01-24 | 1997-06-17 | Roger W Giese | Process for applying multiple layers of a protein and a ligand extender to a surface and to the multiple layer system |
| US4737544A (en) * | 1982-08-12 | 1988-04-12 | Biospecific Technologies, Inc. | Biospecific polymers |
| DE3379659D1 (en) * | 1983-07-29 | 1989-05-24 | Henning Berlin Gmbh | Preactivated surfaces of synthetic materials for immobilizing organochemical and biological substances, process for preparing them and their use |
| CA1260372A (en) * | 1984-04-27 | 1989-09-26 | Elazar Rabbani | Hybridization method for the detection of genetic materials |
| US4788153A (en) * | 1986-10-14 | 1988-11-29 | Eastman Kodak Company | Method for the determination of bilirubin and an element useful therein |
| US5013669A (en) * | 1988-06-01 | 1991-05-07 | Smithkline Diagnostics, Inc. | Mass producible biologically active solid phase devices |
| US5026785A (en) * | 1989-05-12 | 1991-06-25 | The United States Of America As Represented By The Department Of Health And Human Services | Avidin and streptavidin modified water-soluble polymers such as polyacrylamide, and the use thereof in the construction of soluble multivalent macromolecular conjugates |
| US5270193A (en) * | 1989-10-27 | 1993-12-14 | E. I. Dupont De Nemours And Company | Immobilization of biomolecules on perfluorocarbon surfaces |
| WO1991008307A1 (en) * | 1989-12-04 | 1991-06-13 | Microprobe Corporation | Enhanced capture of target nucleic acid by the use of oligonucleotides covalently attached to polymers |
| FR2663040B1 (fr) * | 1990-06-11 | 1995-09-15 | Bio Merieux | Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich. |
| US5200462A (en) * | 1991-01-25 | 1993-04-06 | Eastman Kodak Company | Succinimide containing polymers and lattices prepared from same |
| FR2679255B1 (fr) * | 1991-07-17 | 1993-10-22 | Bio Merieux | Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation. |
| EP0596028B1 (en) * | 1991-07-19 | 1997-04-02 | Upstate Biotechnology, Inc. | Method for detection of mutations |
-
1993
- 1993-06-25 FR FR9307797A patent/FR2707010B1/fr not_active Expired - Fee Related
-
1994
- 1994-06-23 CA CA002126636A patent/CA2126636C/fr not_active Expired - Fee Related
- 1994-06-24 US US08/264,996 patent/US5723344A/en not_active Expired - Fee Related
- 1994-06-24 DK DK94401429T patent/DK0632269T3/da active
- 1994-06-24 EP EP94401429A patent/EP0632269B1/fr not_active Expired - Lifetime
- 1994-06-24 DE DE69419461T patent/DE69419461T2/de not_active Expired - Fee Related
- 1994-06-24 ES ES94401429T patent/ES2133507T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69419461D1 (de) | 1999-08-19 |
| FR2707010A1 (enExample) | 1994-12-30 |
| CA2126636A1 (fr) | 1994-12-26 |
| EP0632269A1 (fr) | 1995-01-04 |
| FR2707010B1 (enExample) | 1995-09-29 |
| US5723344A (en) | 1998-03-03 |
| CA2126636C (fr) | 2001-12-11 |
| EP0632269B1 (fr) | 1999-07-14 |
| ES2133507T3 (es) | 1999-09-16 |
| DK0632269T3 (da) | 2000-02-14 |
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| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |