DE69332826D1 - Opioidpeptide - Google Patents

Opioidpeptide

Info

Publication number
DE69332826D1
DE69332826D1 DE69332826T DE69332826T DE69332826D1 DE 69332826 D1 DE69332826 D1 DE 69332826D1 DE 69332826 T DE69332826 T DE 69332826T DE 69332826 T DE69332826 T DE 69332826T DE 69332826 D1 DE69332826 D1 DE 69332826D1
Authority
DE
Germany
Prior art keywords
amino acid
acid selected
image
identifying group
dimethoxyphenylalanine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69332826T
Other languages
English (en)
Other versions
DE69332826T2 (de
Inventor
Hyuk Kim
Jacques-Pierre Moreau
E Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of DE69332826D1 publication Critical patent/DE69332826D1/de
Application granted granted Critical
Publication of DE69332826T2 publication Critical patent/DE69332826T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE69332826T 1992-11-12 1993-11-04 Opioidpeptide Expired - Fee Related DE69332826T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97494392A 1992-11-12 1992-11-12
PCT/US1993/010711 WO1994011018A1 (en) 1992-11-12 1993-11-04 Opioid peptides

Publications (2)

Publication Number Publication Date
DE69332826D1 true DE69332826D1 (de) 2003-05-08
DE69332826T2 DE69332826T2 (de) 2004-01-29

Family

ID=25522535

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69332826T Expired - Fee Related DE69332826T2 (de) 1992-11-12 1993-11-04 Opioidpeptide

Country Status (15)

Country Link
US (1) US5663295A (de)
EP (1) EP0644772B1 (de)
JP (1) JPH07503485A (de)
AT (1) ATE235911T1 (de)
AU (1) AU672077B2 (de)
CA (1) CA2126697A1 (de)
CZ (1) CZ168194A3 (de)
DE (1) DE69332826T2 (de)
DK (1) DK0644772T3 (de)
ES (1) ES2194861T3 (de)
NZ (1) NZ258345A (de)
PL (1) PL304662A1 (de)
PT (1) PT644772E (de)
RU (1) RU94035760A (de)
WO (1) WO1994011018A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IS4261A (is) * 1994-02-21 1995-08-22 Astra Aktiebolag Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra
EP1164141A3 (de) * 1994-02-21 2002-01-02 AstraZeneca AB Opioid-Peptide und ihre Verwendung zur Behandlung von Schmerz
WO1996032409A1 (fr) * 1995-04-12 1996-10-17 Kyowa Hakko Kogyo Co., Ltd. Facteur de croissance de cellule vegetale
WO1997010262A1 (fr) * 1995-09-11 1997-03-20 Daiichi Pharmaceutical Co., Ltd. Derives peptidiques
JP3746847B2 (ja) * 1996-08-02 2006-02-15 協和醗酵工業株式会社 植物細胞増殖因子
US6703381B1 (en) * 1998-08-14 2004-03-09 Nobex Corporation Methods for delivery therapeutic compounds across the blood-brain barrier
TW509699B (en) 1998-09-24 2002-11-11 Chugau Pharmaceutical Co Ltd Ethylamine derivatives
WO2001036006A1 (en) * 1999-11-19 2001-05-25 Palatin Technologies, Inc. Opioid metallopeptide compositions and methods
WO2001079263A1 (fr) * 2000-04-14 2001-10-25 Nippon Shinyaku Co., Ltd. Derives peptidiques et compositions medicinales
US20070142287A1 (en) * 2005-12-20 2007-06-21 Biomed Solutions, Llc Compositions And Methods For Treatment Of Cancer
AU2009212543B2 (en) * 2008-02-01 2015-07-09 The General Hospital Corporation Use of microvesicles in diagnosis, prognosis and treatment of medical diseases and conditions
EP3461912B1 (de) 2009-09-09 2022-07-13 The General Hospital Corporation Verwendung von mikrovesikeln bei der analyse von nukleinsäureprofilen
WO2011104649A1 (en) * 2010-02-25 2011-09-01 Pfizer Limited Peptide analogues
WO2012031008A2 (en) 2010-08-31 2012-03-08 The General Hospital Corporation Cancer-related biological materials in microvesicles
US20130295574A1 (en) 2010-11-10 2013-11-07 Exosome Diagnostics, Inc. Method for Isolation of Nucleic Acid Containing Particles and Extraction of Nucleic Acids Therefrom
RU2517628C1 (ru) * 2012-12-24 2014-05-27 Государственное научное учреждение Всероссийский научно-исследовательский институт мясной промышленности им. В.М. Горбатова Российской академии сельскохозяйственных наук Способ определения природных аминокислот в составе белков пищевых продуктов
ES2901704T3 (es) 2013-03-15 2022-03-23 Protagonist Therapeutics Inc Análogos de hepcidina y usos de los mismos
EP3960754A3 (de) 2014-05-16 2022-07-06 Protagonist Therapeutics, Inc. Alpha4beta7-integrin-thioether-peptidantagonisten
SG10201810154WA (en) 2014-07-17 2018-12-28 Protagonist Therapeutics Inc Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases
CA3009834A1 (en) 2015-12-30 2017-07-06 Protagonist Therapeutics, Inc. Analogues of hepcidin mimetics with improved in vivo half lives
US10278957B2 (en) 2017-09-11 2019-05-07 Protagonist Therapeutics, Inc. Opioid agonist peptides and uses thereof
AU2018368769A1 (en) * 2017-11-17 2020-07-02 Cytogel Pharma, Llc Polymer agonists of mu opioid receptors
WO2019157268A1 (en) 2018-02-08 2019-08-15 Protagonist Therapeutics, Inc. Conjugated hepcidin mimetics
JP7441955B2 (ja) 2020-01-15 2024-03-01 ヤンセン バイオテツク,インコーポレーテツド インターロイキン23受容体のペプチド阻害剤および炎症性疾患を治療するためのその使用
CN111635335B (zh) * 2020-06-24 2021-07-13 上海交通大学 一种手性γ-氨基酸的合成方法及采用该方法合成的手性γ-氨基酸
IL302996A (en) 2020-11-20 2023-07-01 Janssen Pharmaceutica Nv Compositions of peptide inhibitors of the interleukin-23 receptor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2338925A1 (fr) * 1976-01-26 1977-08-19 Wellcome Found Nouveaux peptides et medicament contenant ces substances
US4216128A (en) * 1979-07-05 1980-08-05 American Home Products Corporation Enkephalin analogues
US4599325A (en) * 1984-02-16 1986-07-08 G. D. Searle & Co. Substituted tyrosyl alanine dipeptide amides
US4880778A (en) * 1986-05-12 1989-11-14 Eastman Kodak Company Combinations having synergistic growth hormone releasing activity and methods for use thereof

Also Published As

Publication number Publication date
JPH07503485A (ja) 1995-04-13
PT644772E (pt) 2003-08-29
PL304662A1 (en) 1995-01-09
DE69332826T2 (de) 2004-01-29
NZ258345A (en) 1996-03-26
DK0644772T3 (da) 2003-06-30
WO1994011018A1 (en) 1994-05-26
AU672077B2 (en) 1996-09-19
CZ168194A3 (en) 1994-12-15
ATE235911T1 (de) 2003-04-15
CA2126697A1 (en) 1994-05-26
US5663295A (en) 1997-09-02
AU5594394A (en) 1994-06-08
EP0644772B1 (de) 2003-04-02
EP0644772A1 (de) 1995-03-29
RU94035760A (ru) 1996-08-10
ES2194861T3 (es) 2003-12-01
EP0644772A4 (de) 1997-01-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee