DE69327583D1 - Substituierte phenylcarbamate und phenylharnstoffe, ihre herstellung und ihre verwendung als 5-ht4-antagonisten - Google Patents

Substituierte phenylcarbamate und phenylharnstoffe, ihre herstellung und ihre verwendung als 5-ht4-antagonisten

Info

Publication number
DE69327583D1
DE69327583D1 DE69327583T DE69327583T DE69327583D1 DE 69327583 D1 DE69327583 D1 DE 69327583D1 DE 69327583 T DE69327583 T DE 69327583T DE 69327583 T DE69327583 T DE 69327583T DE 69327583 D1 DE69327583 D1 DE 69327583D1
Authority
DE
Germany
Prior art keywords
ureas
phenyl
substituted
antagonists
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69327583T
Other languages
English (en)
Other versions
DE69327583T2 (de
Inventor
Alexander William Oxford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929206989A external-priority patent/GB9206989D0/en
Priority claimed from GB929217827A external-priority patent/GB9217827D0/en
Priority claimed from GB929221718A external-priority patent/GB9221718D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE69327583D1 publication Critical patent/DE69327583D1/de
Application granted granted Critical
Publication of DE69327583T2 publication Critical patent/DE69327583T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
DE69327583T 1992-03-31 1993-03-26 Substituierte phenylcarbamate und phenylharnstoffe, ihre herstellung und ihre verwendung als 5-ht4-antagonisten Expired - Fee Related DE69327583T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB929206989A GB9206989D0 (en) 1992-03-31 1992-03-31 Chemical compounds
GB929217827A GB9217827D0 (en) 1992-08-21 1992-08-21 Chemical compounds
GB929221718A GB9221718D0 (en) 1992-10-16 1992-10-16 Chemical compounds
PCT/EP1993/000779 WO1993020071A1 (en) 1992-03-31 1993-03-26 Substituted phenylcarbamates and phenylureas, their preparation and their use as 5-ht antagonists

Publications (2)

Publication Number Publication Date
DE69327583D1 true DE69327583D1 (de) 2000-02-17
DE69327583T2 DE69327583T2 (de) 2000-05-31

Family

ID=27266122

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69327583T Expired - Fee Related DE69327583T2 (de) 1992-03-31 1993-03-26 Substituierte phenylcarbamate und phenylharnstoffe, ihre herstellung und ihre verwendung als 5-ht4-antagonisten

Country Status (17)

Country Link
EP (2) EP0972773A1 (de)
JP (1) JP3236298B2 (de)
AT (1) ATE188697T1 (de)
AU (1) AU663780B2 (de)
CA (1) CA2133083A1 (de)
CZ (1) CZ236894A3 (de)
DE (1) DE69327583T2 (de)
DK (1) DK0640081T3 (de)
ES (1) ES2141763T3 (de)
FI (1) FI944513A (de)
GR (1) GR3032877T3 (de)
HU (1) HUT72321A (de)
NO (1) NO943631L (de)
NZ (1) NZ251687A (de)
PT (1) PT640081E (de)
SK (1) SK116394A3 (de)
WO (1) WO1993020071A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970701174A (ko) * 1994-02-10 1997-03-17 오노다 마사요시 신규한 카바메이트 유도체 및 이의 의약 조성물(Novel carbamate derivative and medicinal composition containing the same)
FR2750991A1 (fr) * 1996-07-12 1998-01-16 Pf Medicament Nouveaux benzodioxannes et 1-(2h)-benzopyrannes, leur preparation et leur utilisation comme medicament
FR2752732B1 (fr) 1996-08-28 1998-11-20 Pf Medicament Forme galenique a liberation prolongee de milnacipran
US6693202B1 (en) 1999-02-16 2004-02-17 Theravance, Inc. Muscarinic receptor antagonists
WO2001042212A1 (en) * 1999-12-07 2001-06-14 Theravance, Inc. Carbamate derivatives having muscarinic receptor antagonist activity
UA73543C2 (uk) * 1999-12-07 2005-08-15 Тераванс, Інк. Похідні сечовини, фармацевтична композиція та застосування похідного при приготуванні лікарського засобу для лікування захворювання, яке опосередковується мускариновим рецептором
US20050032866A1 (en) * 2000-08-07 2005-02-10 Bonhomme Mireille Marguerite Jeanne The use of 5ht4 receptor antagonists in the prophylaxis or treatment of certain cardiovascular conditions
AU2001280187A1 (en) * 2000-08-28 2002-03-13 Toray Industries, Inc. Cyclic amine derivatives
FR2821356A1 (fr) 2001-02-23 2002-08-30 Cerep Nouveaux derives d'arylcarbamates et d'arylurees, preparations et utilisations
FR2843750B1 (fr) * 2002-08-23 2004-10-22 Cerep Composes derives d'arylcarbamates, preparation et utilisations
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
CN100569760C (zh) 2003-11-21 2009-12-16 施万制药 具有β2肾上腺素能受体激动剂和毒蕈碱性受体拮抗剂活性的化合物
EP1778626A1 (de) 2004-08-16 2007-05-02 Theravance, Inc. Zusammensetzungen mit beta2-adrenergen-rezeptoragonist- und muskarinrezeptorantagonist-aktivität
EP1833822A2 (de) 2004-08-16 2007-09-19 Theravance, Inc. Verbindungen mit beta2 adrenerg-rezeptor agonistischer und muscarin-rezeptor antagonistischer aktivität
GB0602778D0 (en) 2006-02-10 2006-03-22 Glaxo Group Ltd Novel compound
CN102284761B (zh) * 2010-06-17 2014-05-28 纬创资通股份有限公司 电子元件解焊方法以及导热模块

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA76475B (en) * 1975-03-10 1977-08-31 Ciba Geigy Ag Indolyalkylpiperidines
JPH0140026B2 (de) * 1978-07-03 1989-08-24 Amerikan Hoomu Purodakutsu Corp
AU611976B2 (en) * 1987-12-24 1991-06-27 John Wyeth & Brother Limited Aroyl urea and carbamic acid derivatives of azabicyclo compounds
DK443489D0 (da) * 1989-09-08 1989-09-08 Ferrosan As Substituerede urinstofforbindelser, deres fremstilling og anvendelse
FR2677019B1 (fr) * 1991-05-27 1994-11-25 Pf Medicament Nouvelles piperidines disubstituees-1,4, leur preparation et leur application en therapeutique.
FR2679555B1 (fr) * 1991-07-25 1993-11-19 Fabre Medicament Pierre Nouveaux derives de l'uree, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
WO1993020071A1 (en) 1993-10-14
NZ251687A (en) 1995-12-21
AU3949793A (en) 1993-11-08
NO943631L (no) 1994-11-29
FI944513A0 (fi) 1994-09-29
DK0640081T3 (da) 2000-06-19
PT640081E (pt) 2000-05-31
JPH07505868A (ja) 1995-06-29
HUT72321A (en) 1996-04-29
CZ236894A3 (en) 1995-09-13
GR3032877T3 (en) 2000-07-31
ES2141763T3 (es) 2000-04-01
EP0640081B1 (de) 2000-01-12
EP0972773A1 (de) 2000-01-19
FI944513A (fi) 1994-11-29
JP3236298B2 (ja) 2001-12-10
SK116394A3 (en) 1995-04-12
EP0640081A1 (de) 1995-03-01
HU9402825D0 (en) 1994-12-28
CA2133083A1 (en) 1993-10-14
ATE188697T1 (de) 2000-01-15
AU663780B2 (en) 1995-10-19
NO943631D0 (no) 1994-09-29
DE69327583T2 (de) 2000-05-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee