DE69324487D1 - Rezeptorbindende region des diphtherietoxius - Google Patents

Rezeptorbindende region des diphtherietoxius

Info

Publication number
DE69324487D1
DE69324487D1 DE69324487T DE69324487T DE69324487D1 DE 69324487 D1 DE69324487 D1 DE 69324487D1 DE 69324487 T DE69324487 T DE 69324487T DE 69324487 T DE69324487 T DE 69324487T DE 69324487 D1 DE69324487 D1 DE 69324487D1
Authority
DE
Germany
Prior art keywords
reciptor
diphtherietoxius
binding region
diphtheria toxin
diphtheria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69324487T
Other languages
English (en)
Other versions
DE69324487T2 (de
Inventor
R Collier
David Eisenberg
Haian Fu
Seunghyon Choe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard College
University of California
Original Assignee
Harvard College
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College, University of California filed Critical Harvard College
Application granted granted Critical
Publication of DE69324487D1 publication Critical patent/DE69324487D1/de
Publication of DE69324487T2 publication Critical patent/DE69324487T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
DE69324487T 1992-05-06 1993-05-03 Rezeptorbindende region des diphtherietoxius Expired - Fee Related DE69324487T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88139492A 1992-05-06 1992-05-06
PCT/US1993/004166 WO1993021769A1 (en) 1992-05-06 1993-05-03 Diphtheria toxin receptor-binding region

Publications (2)

Publication Number Publication Date
DE69324487D1 true DE69324487D1 (de) 1999-05-20
DE69324487T2 DE69324487T2 (de) 1999-08-12

Family

ID=25378382

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69324487T Expired - Fee Related DE69324487T2 (de) 1992-05-06 1993-05-03 Rezeptorbindende region des diphtherietoxius

Country Status (10)

Country Link
US (1) US5843711A (de)
EP (1) EP0643559B1 (de)
JP (1) JP3506431B2 (de)
AT (1) ATE178907T1 (de)
AU (1) AU4230493A (de)
CA (1) CA2135052A1 (de)
DE (1) DE69324487T2 (de)
ES (1) ES2130265T3 (de)
GR (1) GR3030141T3 (de)
WO (1) WO1993021769A1 (de)

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US20220127368A1 (en) 2019-02-19 2022-04-28 The Regents Of The University Of Colorado, A Body Corporate Bispecific immunotoxins targeting human cd25+ccr4+ tumors and regulatory t-cells
JP7239509B6 (ja) 2019-02-22 2023-03-28 ファイザー・インク 細菌多糖類を精製するための方法
WO2020208502A1 (en) 2019-04-10 2020-10-15 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof
WO2021021729A1 (en) 2019-07-31 2021-02-04 Sanofi Pasteur Inc. Multivalent pneumococcal polysaccharide-protein conjugate compositions and methods of using the same
US20220401544A1 (en) 2019-09-27 2022-12-22 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
EP4051696A1 (de) 2019-11-01 2022-09-07 Pfizer Inc. Escherichia-zusammensetzungen und verfahren dafür
CA3161857A1 (en) 2019-11-22 2021-05-27 Glaxosmithkline Biologicals Sa Dosage and administration of a bacterial saccharide glycoconjugate vaccine
KR20220144393A (ko) 2020-02-21 2022-10-26 화이자 인코포레이티드 당류의 정제
MX2022010350A (es) 2020-02-23 2022-09-19 Pfizer Composiciones de esquerichia coli y sus metodos.
JP2023546446A (ja) 2020-10-22 2023-11-02 ファイザー・インク 細菌多糖を精製する方法
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WO2022097010A1 (en) 2020-11-04 2022-05-12 Pfizer Inc. Immunogenic compositions for use in pneumococcal vaccines
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Family Cites Families (3)

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US4709017A (en) * 1985-06-07 1987-11-24 President And Fellows Of Harvard College Modified toxic vaccines
US4950740A (en) * 1987-03-17 1990-08-21 Cetus Corporation Recombinant diphtheria vaccines
IL89504A0 (en) * 1988-03-08 1989-09-10 Univ Wyoming Diphtheria toxin derivative,process for the preparation thereof and pharmaceutical composition containing the same

Also Published As

Publication number Publication date
WO1993021769A1 (en) 1993-11-11
JP3506431B2 (ja) 2004-03-15
DE69324487T2 (de) 1999-08-12
EP0643559A1 (de) 1995-03-22
EP0643559B1 (de) 1999-04-14
ES2130265T3 (es) 1999-07-01
GR3030141T3 (en) 1999-08-31
AU4230493A (en) 1993-11-29
EP0643559A4 (de) 1997-01-15
JPH07506821A (ja) 1995-07-27
CA2135052A1 (en) 1993-11-11
ATE178907T1 (de) 1999-04-15
US5843711A (en) 1998-12-01

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