ATE178907T1 - Rezeptorbindende region des diphtherietoxius - Google Patents

Rezeptorbindende region des diphtherietoxius

Info

Publication number
ATE178907T1
ATE178907T1 AT93911012T AT93911012T ATE178907T1 AT E178907 T1 ATE178907 T1 AT E178907T1 AT 93911012 T AT93911012 T AT 93911012T AT 93911012 T AT93911012 T AT 93911012T AT E178907 T1 ATE178907 T1 AT E178907T1
Authority
AT
Austria
Prior art keywords
receptor
toxius
diphtherial
binding region
diphtheria toxin
Prior art date
Application number
AT93911012T
Other languages
English (en)
Inventor
R John Collier
David Eisenberg
Haian Fu
Seunghyon Choe
Original Assignee
Harvard College
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College, Univ California filed Critical Harvard College
Application granted granted Critical
Publication of ATE178907T1 publication Critical patent/ATE178907T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Electronic Switches (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
AT93911012T 1992-05-06 1993-05-03 Rezeptorbindende region des diphtherietoxius ATE178907T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88139492A 1992-05-06 1992-05-06

Publications (1)

Publication Number Publication Date
ATE178907T1 true ATE178907T1 (de) 1999-04-15

Family

ID=25378382

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93911012T ATE178907T1 (de) 1992-05-06 1993-05-03 Rezeptorbindende region des diphtherietoxius

Country Status (10)

Country Link
US (1) US5843711A (de)
EP (1) EP0643559B1 (de)
JP (1) JP3506431B2 (de)
AT (1) ATE178907T1 (de)
AU (1) AU4230493A (de)
CA (1) CA2135052A1 (de)
DE (1) DE69324487T2 (de)
ES (1) ES2130265T3 (de)
GR (1) GR3030141T3 (de)
WO (1) WO1993021769A1 (de)

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ES2883343T3 (es) 2014-01-21 2021-12-07 Pfizer Polisacáridos capsulares de Streptococcus pneumoniae y conjugados de los mismos
US11160855B2 (en) 2014-01-21 2021-11-02 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
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IL267733B2 (en) 2017-01-31 2023-10-01 Pfizer NEISSERIA MENINGITIDIS preparations and methods therefor
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EP3927731A4 (de) 2019-02-19 2022-12-28 The Regents of the University of Colorado, a body corporate Bispezifische immunotoxine zur targeting von menschlichen cd25s-ccr4+ tumoren und regulatorischen t-zellen
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Family Cites Families (3)

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US4709017A (en) * 1985-06-07 1987-11-24 President And Fellows Of Harvard College Modified toxic vaccines
US4950740A (en) * 1987-03-17 1990-08-21 Cetus Corporation Recombinant diphtheria vaccines
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Also Published As

Publication number Publication date
ES2130265T3 (es) 1999-07-01
EP0643559A4 (de) 1997-01-15
DE69324487T2 (de) 1999-08-12
WO1993021769A1 (en) 1993-11-11
JP3506431B2 (ja) 2004-03-15
AU4230493A (en) 1993-11-29
US5843711A (en) 1998-12-01
CA2135052A1 (en) 1993-11-11
EP0643559B1 (de) 1999-04-14
DE69324487D1 (de) 1999-05-20
GR3030141T3 (en) 1999-08-31
JPH07506821A (ja) 1995-07-27
EP0643559A1 (de) 1995-03-22

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