DE69323465T2 - Sulfatase-ähnliches Protein aus Knochen und Verfahren zu dessen Herstellung - Google Patents
Sulfatase-ähnliches Protein aus Knochen und Verfahren zu dessen HerstellungInfo
- Publication number
- DE69323465T2 DE69323465T2 DE69323465T DE69323465T DE69323465T2 DE 69323465 T2 DE69323465 T2 DE 69323465T2 DE 69323465 T DE69323465 T DE 69323465T DE 69323465 T DE69323465 T DE 69323465T DE 69323465 T2 DE69323465 T2 DE 69323465T2
- Authority
- DE
- Germany
- Prior art keywords
- bone
- protein
- osf
- metabolic diseases
- sulfatase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 210000000988 bone and bone Anatomy 0.000 title abstract 7
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 241000124008 Mammalia Species 0.000 abstract 2
- 208000030159 metabolic disease Diseases 0.000 abstract 2
- 102000055008 Matrilin Proteins Human genes 0.000 abstract 1
- 108010072582 Matrilin Proteins Proteins 0.000 abstract 1
- 102000005262 Sulfatase Human genes 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 230000011164 ossification Effects 0.000 abstract 1
- 108060007951 sulfatase Proteins 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate group Chemical group S(=O)(=O)([O-])[O-] QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23003092 | 1992-08-28 | ||
| JP4324034A JPH06121678A (ja) | 1992-08-28 | 1992-12-03 | 骨関連サルファターゼ様タンパク質およびその製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69323465D1 DE69323465D1 (de) | 1999-03-25 |
| DE69323465T2 true DE69323465T2 (de) | 1999-08-19 |
Family
ID=26529110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69323465T Expired - Fee Related DE69323465T2 (de) | 1992-08-28 | 1993-08-25 | Sulfatase-ähnliches Protein aus Knochen und Verfahren zu dessen Herstellung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5627050A (de) |
| EP (1) | EP0590309B1 (de) |
| JP (1) | JPH06121678A (de) |
| AT (1) | ATE176685T1 (de) |
| AU (1) | AU663215B2 (de) |
| CA (1) | CA2104995A1 (de) |
| DE (1) | DE69323465T2 (de) |
| DK (1) | DK0590309T3 (de) |
| ES (1) | ES2130198T3 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3472587B2 (ja) * | 1992-08-28 | 2003-12-02 | アベンティス ファーマ株式会社 | 骨関連カルボキシペプチダーゼ様タンパク質およびその製造法 |
| US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20030195162A1 (en) * | 1999-09-17 | 2003-10-16 | Cohn Daniel H. | Genetic marker for spondyloepimetaphyseal dysplasia |
| AU2003201160A1 (en) * | 2002-01-14 | 2003-07-24 | Bayer Aktiengesellschaft | Regulation of human sulfatase |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2041280A1 (en) * | 1990-05-10 | 1991-11-11 | Yosuke Sawada | Arylsulfatase |
| JP3560252B2 (ja) * | 1992-08-28 | 2004-09-02 | アベンティス ファーマ株式会社 | 骨関連カドヘリン様タンパク質およびその製造法 |
| JP3472587B2 (ja) * | 1992-08-28 | 2003-12-02 | アベンティス ファーマ株式会社 | 骨関連カルボキシペプチダーゼ様タンパク質およびその製造法 |
-
1992
- 1992-12-03 JP JP4324034A patent/JPH06121678A/ja active Pending
-
1993
- 1993-08-25 AT AT93113603T patent/ATE176685T1/de not_active IP Right Cessation
- 1993-08-25 ES ES93113603T patent/ES2130198T3/es not_active Expired - Lifetime
- 1993-08-25 EP EP93113603A patent/EP0590309B1/de not_active Expired - Lifetime
- 1993-08-25 DE DE69323465T patent/DE69323465T2/de not_active Expired - Fee Related
- 1993-08-25 DK DK93113603T patent/DK0590309T3/da active
- 1993-08-27 CA CA002104995A patent/CA2104995A1/en not_active Abandoned
- 1993-08-27 AU AU44921/93A patent/AU663215B2/en not_active Ceased
-
1995
- 1995-05-22 US US08/445,586 patent/US5627050A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0590309A3 (de) | 1995-02-15 |
| JPH06121678A (ja) | 1994-05-06 |
| DE69323465D1 (de) | 1999-03-25 |
| US5627050A (en) | 1997-05-06 |
| DK0590309T3 (da) | 1999-09-20 |
| EP0590309A2 (de) | 1994-04-06 |
| AU663215B2 (en) | 1995-09-28 |
| AU4492193A (en) | 1994-03-03 |
| EP0590309B1 (de) | 1999-02-10 |
| CA2104995A1 (en) | 1994-03-01 |
| ES2130198T3 (es) | 1999-07-01 |
| ATE176685T1 (de) | 1999-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |