DE69322992T2 - Optisch reines Cis-oxalato(trans-l-1,2-Cyclohexandiamine)Pt(II) und Verfahren zur Auflösung von optischen Isomeren einer Platinkomplexverbindung - Google Patents

Optisch reines Cis-oxalato(trans-l-1,2-Cyclohexandiamine)Pt(II) und Verfahren zur Auflösung von optischen Isomeren einer Platinkomplexverbindung

Info

Publication number
DE69322992T2
DE69322992T2 DE69322992T DE69322992T DE69322992T2 DE 69322992 T2 DE69322992 T2 DE 69322992T2 DE 69322992 T DE69322992 T DE 69322992T DE 69322992 T DE69322992 T DE 69322992T DE 69322992 T2 DE69322992 T2 DE 69322992T2
Authority
DE
Germany
Prior art keywords
oxalato
cyclohexanediamine
trans
complex compound
optical isomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69322992T
Other languages
English (en)
Other versions
DE69322992D1 (de
DE69322992C5 (de
Inventor
Takeshi Tozawa
Yasunobu Komoda
Junji Ohnishi
Yukie Masuda
Junichi Taniuchi
Chihiro Nakanishi
Koji Okamoto
Yuko Ohnishini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Debiopharm SA
Original Assignee
Tanaka Kikinzoku Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26356339&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69322992(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP5019508A external-priority patent/JP2673331B2/ja
Application filed by Tanaka Kikinzoku Kogyo KK filed Critical Tanaka Kikinzoku Kogyo KK
Publication of DE69322992D1 publication Critical patent/DE69322992D1/de
Publication of DE69322992T2 publication Critical patent/DE69322992T2/de
Application granted granted Critical
Publication of DE69322992C5 publication Critical patent/DE69322992C5/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DE69322992T 1992-04-22 1993-04-09 Optisch reines Cis-oxalato(trans-l-1,2-Cyclohexandiamine)Pt(II) und Verfahren zur Auflösung von optischen Isomeren einer Platinkomplexverbindung Expired - Lifetime DE69322992C5 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP129668/92 1992-04-22
JP4129668A JPH06287021A (ja) 1992-04-22 1992-04-22 光学活性な白金錯化合物の光学的分割方法
JP5019508A JP2673331B2 (ja) 1993-01-12 1993-01-12 光学的に高純度なシス―オキザラート（トランス―１―１，２―シクロヘキサンジアミン）白金（▲ｉｉ▼）
JP19508/93 1993-01-12

Publications (3)

Publication Number Publication Date
DE69322992D1 DE69322992D1 (de) 1999-02-25
DE69322992T2 true DE69322992T2 (de) 1999-05-27
DE69322992C5 DE69322992C5 (de) 2009-08-13

Family

ID=26356339

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69322992T Expired - Lifetime DE69322992C5 (de) 1992-04-22 1993-04-09 Optisch reines Cis-oxalato(trans-l-1,2-Cyclohexandiamine)Pt(II) und Verfahren zur Auflösung von optischen Isomeren einer Platinkomplexverbindung

Country Status (5)

Country Link
US (1) US5298642A (de)
EP (1) EP0567438B1 (de)
JP (1) JPH06287021A (de)
DE (1) DE69322992C5 (de)
ES (1) ES2125320T3 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3025602B2 (ja) * 1993-05-21 2000-03-27 デビオファーム エス．アー． 光学的に高純度なシス−オキザラート（トランス−ｌ−１，２−シクロヘキサンジアミン）白金（ＩＩ）錯体の製造方法
JPH09278785A (ja) * 1996-04-10 1997-10-28 Tanaka Kikinzoku Kogyo Kk 白金化合物の製造方法
EP0801070B1 (de) * 1996-04-10 2003-04-16 Debiopharm S.A. Verfahren zur Herstellung von Platin Verbindungen
JP3154399B2 (ja) * 1996-07-04 2001-04-09 デビオファーム エス．アー． 白金化合物の製造方法
GB9804013D0 (en) * 1998-02-25 1998-04-22 Sanofi Sa Formulations
AUPR330201A0 (en) 2001-02-23 2001-03-22 University Of Sydney, The Metal complexes and therapeutic uses thereof
ES2183714B1 (es) * 2001-05-25 2004-01-16 Desynth S A Un procedimiento para la fabricacion de oxalato de (1r,2r-ciclohexanodiamina)-platino (ii).
WO2003004505A1 (en) 2001-07-02 2003-01-16 Debiopharm S.A. Oxaliplatin active substance with a very low content of oxalic acid
US6476068B1 (en) 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
EP2330110A1 (de) 2003-11-25 2011-06-08 Platco Technologies (Proprietary) Limited Platin(II) Komplexe, Herstellung und Verwendung
US7608730B2 (en) 2004-02-05 2009-10-27 Fresenius Kabi Oncology Limited Process for the preparation of an anti-tumor platinum (II)—complex
DE102004005906B3 (de) * 2004-02-05 2005-09-29 W.C. Heraeus Gmbh Verfahren zur Herstellung von 1,2-Diaminocylohexan-Platin(II)-Komplexen
KR20070048706A (ko) * 2004-07-12 2007-05-09 시코르, 인크. ｃｉｓ-디요오도-(ｔｒａｎｓ-Ｌ-1,2-시클로헥산디아민)백금(Ⅱ) 착물 및 고순도 옥살리플라틴의 제조 방법
JP2006248978A (ja) * 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
BRPI0708004A2 (pt) 2006-01-30 2011-05-17 Platco Technologies Proprietary Ltd preparação de complexos de platina (ii)
WO2009093133A1 (en) * 2008-01-25 2009-07-30 Medichem, S.A. Method for determining the enantiomeric purity of indane derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
JPS6034958B2 (ja) * 1978-09-02 1985-08-12 喜徳 喜谷 新規白金錯体
AU538863B2 (en) * 1980-05-27 1984-08-30 Bristol-Myers Company Platinum complex salts have anti-tumor property
JPS595198A (ja) * 1982-06-30 1984-01-12 Seiwa Kasei Kk 光学分割剤、その合成法およびそれを使用した光学分割方法
US4599352A (en) * 1984-03-01 1986-07-08 The United States Of America As Represented By The Department Of Health And Human Services Antineoplastic platinum (IV) complexes and compositions
US4550187A (en) * 1984-04-12 1985-10-29 The Research Foundation Of State University Of New York Synthesis of platinum (IV) antineoplastic agents
JPS61122283A (ja) * 1984-11-20 1986-06-10 Daicel Chem Ind Ltd グリセリン誘導体の光学分割方法
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
JPS62277147A (ja) * 1986-05-23 1987-12-02 Matsushita Electric Works Ltd 薄膜の製法
CS269719B1 (en) * 1986-12-29 1990-05-14 Kiss Frantisek Platinum cytostatic
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
JP2896589B2 (ja) * 1990-03-12 1999-05-31 チッソ株式会社 光学異性体分離剤

Also Published As

Publication number Publication date
DE69322992D1 (de) 1999-02-25
EP0567438B1 (de) 1999-01-13
ES2125320T3 (es) 1999-03-01
JPH06287021A (ja) 1994-10-11
DE69322992C5 (de) 2009-08-13
EP0567438A1 (de) 1993-10-27
US5298642A (en) 1994-03-29

Similar Documents

Publication Publication Date Title
DE69322992D1 (de) Optisch reines Cis-oxalato(trans-l-1,2-Cyclohexandiamine)Pt(II) und Verfahren zur Auflösung von optischen Isomeren einer Platinkomplexverbindung
DE69331048T2 (de) Verfahren zur Herstellung von Cis-Oxalato (Trans-L-1,2-Cyclohexandiamin) Pt Komplex mit hoher optischer Reinheit
DE3888233D1 (de) Optisches Mehrfaserbauteil und Verfahren zu dessen Herstellung.
DE68915602T2 (de) Verfahren zur Herstellung einer optischen Flüssigkristall-Vorrichtung.
DE69227786D1 (de) Verfahren zur Herstellung von Polycarbonat
DE68926421D1 (de) Verfahren zur Entfernung von gelösten Gasen aus einer Flüssigkeit
DE3888242T2 (de) Vorrichtung und Verfahren zum Schneiden von optischen Fasern.
DE69317169T2 (de) Verfahren zur Delignifizierung von chemischen Zellstoffen
KR950700534A (ko) 패턴화된 기판의 광학 검사용 장치(apparatus for optical inspection of patterned substrates)
DE69311922D1 (de) Optische Vorrichtung und Verfahren zu deren Herstellung
DE69116166D1 (de) Verfahren zur herstellung von optischen fasergittern
DE69004140T3 (de) Verfahren zum Ziehen von optischen Fasern.
DE68923940T2 (de) Standardsubstanz zur optischen Kalibrierung und Verfahren zu deren Herstellung.
DE59308090D1 (de) Verfahren zur Ueberwachung von Filterelemente
DE69118997D1 (de) Verfahren und Vorrichtung zur Herstellung von hermetisch beschichteten optischen Fasern
DE69207846T2 (de) Verfahren zum Schneiden einer optischen Faser
DE3577354D1 (de) Verfahren und vorrichtung zur herstellung eines reflektionshologrammes zur verknuepfung von nichtlinearen optischen elementen.
DE69309032D1 (de) Verfahren zur Überwachung von hermetisch überzogenen optischen Fibern
DE69229088T2 (de) Verfahren zur herstellung von polycarbonat
DE69630867D1 (de) Verfahren zur herstellung von optischen linsen
DE3784494D1 (de) Verfahren und vorrichtung zum aufwickeln von lichtleitfasern.
DE69331256D1 (de) Verfahren zur Herstellung von Chlorogalliumphtalocyaninkristallen
DE3750703T2 (de) Transparenter optischer Gegenstand und Verfahren zu seiner Herstellung.
DE3671829D1 (de) Verfahren und vorrichtung zur optischen praesentation von brillenfassungen.
DE69224454D1 (de) Verfahren zur Herstellung von planaren optischen Wellenleitern

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DEBIOPHARM S.A., LAUSANNE, CH

8310 Action for declaration of annulment
8312 Partial invalidation
8394 Patent changed during the nullification procedure (changed patent specification reprinted)