DE69314183T2 - Trizyklische verbindungen mit pharmazeutischer wirkung - Google Patents
Trizyklische verbindungen mit pharmazeutischer wirkungInfo
- Publication number
- DE69314183T2 DE69314183T2 DE69314183T DE69314183T DE69314183T2 DE 69314183 T2 DE69314183 T2 DE 69314183T2 DE 69314183 T DE69314183 T DE 69314183T DE 69314183 T DE69314183 T DE 69314183T DE 69314183 T2 DE69314183 T2 DE 69314183T2
- Authority
- DE
- Germany
- Prior art keywords
- alkyl
- tetrazol
- pct
- tricyclic compounds
- carbamoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929223352A GB9223352D0 (en) | 1992-11-06 | 1992-11-06 | Tricyclic compounds |
PCT/GB1993/002281 WO1994011354A1 (en) | 1992-11-06 | 1993-11-04 | Tricyclic compounds with pharmaceutical activity |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69314183D1 DE69314183D1 (de) | 1997-10-30 |
DE69314183T2 true DE69314183T2 (de) | 1998-01-15 |
Family
ID=10724693
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69314183T Expired - Lifetime DE69314183T2 (de) | 1992-11-06 | 1993-11-04 | Trizyklische verbindungen mit pharmazeutischer wirkung |
Country Status (13)
Country | Link |
---|---|
US (1) | US5789417A (de) |
EP (1) | EP0667864B1 (de) |
JP (1) | JP3271667B2 (de) |
AT (1) | ATE158578T1 (de) |
AU (1) | AU5376094A (de) |
DE (1) | DE69314183T2 (de) |
DK (1) | DK0667864T3 (de) |
ES (1) | ES2107688T3 (de) |
GB (1) | GB9223352D0 (de) |
GR (1) | GR3024875T3 (de) |
IL (1) | IL107306A0 (de) |
WO (1) | WO1994011354A1 (de) |
ZA (1) | ZA937756B (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10260877A1 (de) * | 2002-12-23 | 2004-07-01 | Beiersdorf Ag | Stabile zinkoxidhaltige Öl-in-Wasser-Emulsionen |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9320113D0 (en) * | 1993-09-29 | 1993-11-17 | Zeneca Ltd | Tricyclic derivatives |
GB9904275D0 (en) | 1999-02-24 | 1999-04-21 | Cancer Res Campaign Tech | Anti-cancer compounds |
US6368818B1 (en) * | 2000-10-12 | 2002-04-09 | Qingzhong Kong | Methods and compositions for the visualization of cellular organelles using tetrazolium salts |
US7524872B2 (en) * | 2000-09-15 | 2009-04-28 | Qingzhong Kong | Method and composition for treating cancer using cellular organelle crystallizing agents |
EP2332962A1 (de) | 2001-08-31 | 2011-06-15 | BTG International Limited | Cyclopenta[g]Chinazoline-Derivate zur Verwendung in der Behandlung von Allergien oder Entzündungen |
ATE526028T1 (de) | 2001-08-31 | 2011-10-15 | Btg Int Ltd | Verwendung von cyclopentaägüchinazoline-derivaten zur krebsbehandlung |
GB0121214D0 (en) | 2001-08-31 | 2001-10-24 | Btg Int Ltd | Synthetic method |
WO2009115776A1 (en) | 2008-03-18 | 2009-09-24 | Btg International Limited | Cyclopenta[g]quinazoline derivatives for the treatment of rheumatoid arthritis or acute myeloid leukaemia |
EA201291302A1 (ru) | 2010-07-19 | 2013-09-30 | Оникс Фармасьютикалз, Инк. | Синтез циклопентахиназолинов |
JP2014513663A (ja) * | 2010-12-22 | 2014-06-05 | オニックス ファーマシューティカルズ,インコーポレイティド | 効率的なペプチドカップリングおよびシクロペンタ[g]キナゾリン3ナトリウム塩の合成および単離でのそれらの使用 |
US8883857B2 (en) | 2012-12-07 | 2014-11-11 | Baylor College Of Medicine | Small molecule xanthine oxidase inhibitors and methods of use |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2065653B (en) * | 1979-12-19 | 1983-03-09 | Nat Res Dev | Anti-cancer quinazoline derivatives |
GB8513754D0 (en) * | 1985-05-31 | 1985-07-03 | Jones T R | Anti-cancer quinazoline derivatives |
GB8607683D0 (en) * | 1986-03-27 | 1986-04-30 | Ici Plc | Anti-tumor agents |
US5187167A (en) * | 1986-03-27 | 1993-02-16 | Imperial Chemical Industries Plc | Pharmaceutical compositions comprising quinazolin-4-one derivatives |
GB8707053D0 (en) * | 1987-03-25 | 1987-04-29 | Ici Plc | Anti-tumour agents |
US5252573A (en) * | 1988-12-15 | 1993-10-12 | Imperial Chemical Industries Plc | Anti-tumor agents |
GB8829296D0 (en) * | 1988-12-15 | 1989-01-25 | Ici Plc | Anti-tumour compounds |
US4925939A (en) * | 1989-01-05 | 1990-05-15 | Sloan-Kettering Institute For Cancer Research | 6,7-dihydropyrrol[3,4-c]pyrido[2,3-d]pyrimidine derivatives |
CA2021042A1 (en) * | 1989-07-21 | 1991-01-22 | Fabrizio Marazza | Salts of n ,n -methylene-5,6,7,8-tetrahydrofolic acid |
US5077404A (en) * | 1989-08-29 | 1991-12-31 | Piper James R | Cyclized 5,10-dideazaaminopterin compounds |
EP0438261A3 (en) * | 1990-01-16 | 1992-02-26 | Takeda Chemical Industries, Ltd. | Condensed heterocyclic glutamic acid derivatives, their production and use |
FR2659330B1 (fr) * | 1990-03-09 | 1994-02-11 | Sapec Sa | Composes diastereoisomeres derivant de l'acide tetrahydrofolique, procede de preparation et utilisation dans la synthese de diastereomeres 6s et 6r de folates reduits. |
GB9013615D0 (en) * | 1990-06-19 | 1990-08-08 | Wellcome Found | Pharmaceutical compounds |
ZA917355B (en) * | 1990-09-17 | 1992-08-26 | Agouron Pharma | Antiproliferative substituted naphthalene compounds |
YU155791A (sh) * | 1990-09-25 | 1994-01-20 | Agouron Pharmaceuticals Inc. | Antiproliferativna supstituisana triciklična jedinjenja |
GB9105771D0 (en) * | 1991-03-19 | 1991-05-01 | Cancer Res Inst Royal | Anti-cancer compounds |
GB9205320D0 (en) * | 1992-03-11 | 1992-04-22 | Ici Plc | Anti-tumour compounds |
WO1994003439A1 (en) * | 1992-07-29 | 1994-02-17 | Agouron Pharmaceuticals, Inc. | Antiproliferative tricyclic compounds |
-
1992
- 1992-11-06 GB GB929223352A patent/GB9223352D0/en active Pending
-
1993
- 1993-10-17 IL IL107306A patent/IL107306A0/xx unknown
- 1993-10-19 ZA ZA937756A patent/ZA937756B/xx unknown
- 1993-11-04 WO PCT/GB1993/002281 patent/WO1994011354A1/en active IP Right Grant
- 1993-11-04 DE DE69314183T patent/DE69314183T2/de not_active Expired - Lifetime
- 1993-11-04 DK DK93924165.9T patent/DK0667864T3/da active
- 1993-11-04 AU AU53760/94A patent/AU5376094A/en not_active Abandoned
- 1993-11-04 ES ES93924165T patent/ES2107688T3/es not_active Expired - Lifetime
- 1993-11-04 US US08/432,161 patent/US5789417A/en not_active Expired - Lifetime
- 1993-11-04 AT AT93924165T patent/ATE158578T1/de active
- 1993-11-04 EP EP93924165A patent/EP0667864B1/de not_active Expired - Lifetime
- 1993-11-04 JP JP51182994A patent/JP3271667B2/ja not_active Expired - Fee Related
-
1997
- 1997-09-26 GR GR970402521T patent/GR3024875T3/el unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10260877A1 (de) * | 2002-12-23 | 2004-07-01 | Beiersdorf Ag | Stabile zinkoxidhaltige Öl-in-Wasser-Emulsionen |
Also Published As
Publication number | Publication date |
---|---|
GR3024875T3 (en) | 1998-01-30 |
AU5376094A (en) | 1994-06-08 |
ZA937756B (en) | 1994-05-11 |
JPH08505838A (ja) | 1996-06-25 |
GB9223352D0 (en) | 1992-12-23 |
US5789417A (en) | 1998-08-04 |
EP0667864B1 (de) | 1997-09-24 |
JP3271667B2 (ja) | 2002-04-02 |
EP0667864A1 (de) | 1995-08-23 |
WO1994011354A1 (en) | 1994-05-26 |
ES2107688T3 (es) | 1997-12-01 |
DK0667864T3 (da) | 1998-05-04 |
IL107306A0 (en) | 1994-01-25 |
ATE158578T1 (de) | 1997-10-15 |
DE69314183D1 (de) | 1997-10-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |