IL107306A0 - Tricyclic compounds - Google Patents

Tricyclic compounds

Info

Publication number
IL107306A0
IL107306A0 IL107306A IL10730693A IL107306A0 IL 107306 A0 IL107306 A0 IL 107306A0 IL 107306 A IL107306 A IL 107306A IL 10730693 A IL10730693 A IL 10730693A IL 107306 A0 IL107306 A0 IL 107306A0
Authority
IL
Israel
Prior art keywords
alkyl
tetrazol
pct
carbamoyl
sec
Prior art date
Application number
IL107306A
Other languages
English (en)
Original Assignee
Zeneca Ltd
Britsh Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd, Britsh Technology Group Ltd filed Critical Zeneca Ltd
Publication of IL107306A0 publication Critical patent/IL107306A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL107306A 1992-11-06 1993-10-17 Tricyclic compounds IL107306A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929223352A GB9223352D0 (en) 1992-11-06 1992-11-06 Tricyclic compounds

Publications (1)

Publication Number Publication Date
IL107306A0 true IL107306A0 (en) 1994-01-25

Family

ID=10724693

Family Applications (1)

Application Number Title Priority Date Filing Date
IL107306A IL107306A0 (en) 1992-11-06 1993-10-17 Tricyclic compounds

Country Status (13)

Country Link
US (1) US5789417A (xx)
EP (1) EP0667864B1 (xx)
JP (1) JP3271667B2 (xx)
AT (1) ATE158578T1 (xx)
AU (1) AU5376094A (xx)
DE (1) DE69314183T2 (xx)
DK (1) DK0667864T3 (xx)
ES (1) ES2107688T3 (xx)
GB (1) GB9223352D0 (xx)
GR (1) GR3024875T3 (xx)
IL (1) IL107306A0 (xx)
WO (1) WO1994011354A1 (xx)
ZA (1) ZA937756B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9320113D0 (en) * 1993-09-29 1993-11-17 Zeneca Ltd Tricyclic derivatives
GB9904275D0 (en) 1999-02-24 1999-04-21 Cancer Res Campaign Tech Anti-cancer compounds
US6368818B1 (en) * 2000-10-12 2002-04-09 Qingzhong Kong Methods and compositions for the visualization of cellular organelles using tetrazolium salts
US7524872B2 (en) * 2000-09-15 2009-04-28 Qingzhong Kong Method and composition for treating cancer using cellular organelle crystallizing agents
GB0121214D0 (en) 2001-08-31 2001-10-24 Btg Int Ltd Synthetic method
JP4328202B2 (ja) 2001-08-31 2009-09-09 ビーティージー・インターナショナル・リミテッド 抗癌シクロペンタ[g]キナゾリン化合物
ES2373644T3 (es) 2001-08-31 2012-02-07 Btg International Limited Uso de derivados de ciclopenta[g]quinazolina para el tratamiento del c�?ncer.
DE10260877A1 (de) * 2002-12-23 2004-07-01 Beiersdorf Ag Stabile zinkoxidhaltige Öl-in-Wasser-Emulsionen
ES2387334T3 (es) 2008-03-18 2012-09-20 Btg International Limited Derivados de ciclopenta[g]quinazolina para el tratamiento de la artritis reumatoide o la leucemia mielocítica aguda
WO2012011939A2 (en) 2010-07-19 2012-01-26 Onyx Pharmaceuticals, Inc. Synthesis of cyclopentaquinazolines
EA201390635A1 (ru) * 2010-12-22 2014-09-30 Оникс Фармасьютикалз, Инк. Эффективные реакции пептидного сочетания и их применение для получения и выделения тринатриевой соли циклопента[g]хиназолина
US8883857B2 (en) 2012-12-07 2014-11-11 Baylor College Of Medicine Small molecule xanthine oxidase inhibitors and methods of use

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2065653B (en) * 1979-12-19 1983-03-09 Nat Res Dev Anti-cancer quinazoline derivatives
GB8513754D0 (en) * 1985-05-31 1985-07-03 Jones T R Anti-cancer quinazoline derivatives
US5187167A (en) * 1986-03-27 1993-02-16 Imperial Chemical Industries Plc Pharmaceutical compositions comprising quinazolin-4-one derivatives
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US5252573A (en) * 1988-12-15 1993-10-12 Imperial Chemical Industries Plc Anti-tumor agents
GB8829296D0 (en) * 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds
US4925939A (en) * 1989-01-05 1990-05-15 Sloan-Kettering Institute For Cancer Research 6,7-dihydropyrrol[3,4-c]pyrido[2,3-d]pyrimidine derivatives
CA2021042A1 (en) * 1989-07-21 1991-01-22 Fabrizio Marazza Salts of n ,n -methylene-5,6,7,8-tetrahydrofolic acid
US5077404A (en) * 1989-08-29 1991-12-31 Piper James R Cyclized 5,10-dideazaaminopterin compounds
EP0438261A3 (en) * 1990-01-16 1992-02-26 Takeda Chemical Industries, Ltd. Condensed heterocyclic glutamic acid derivatives, their production and use
FR2659330B1 (fr) * 1990-03-09 1994-02-11 Sapec Sa Composes diastereoisomeres derivant de l'acide tetrahydrofolique, procede de preparation et utilisation dans la synthese de diastereomeres 6s et 6r de folates reduits.
GB9013615D0 (en) * 1990-06-19 1990-08-08 Wellcome Found Pharmaceutical compounds
IL99500A0 (en) * 1990-09-17 1992-08-18 Agouron Pharma Naphthalene compounds,processes for the preparation thereof and pharmaceutical compositions containing the same
YU155791A (sh) * 1990-09-25 1994-01-20 Agouron Pharmaceuticals Inc. Antiproliferativna supstituisana triciklična jedinjenja
GB9105771D0 (en) * 1991-03-19 1991-05-01 Cancer Res Inst Royal Anti-cancer compounds
GB9205320D0 (en) * 1992-03-11 1992-04-22 Ici Plc Anti-tumour compounds
WO1994003439A1 (en) * 1992-07-29 1994-02-17 Agouron Pharmaceuticals, Inc. Antiproliferative tricyclic compounds

Also Published As

Publication number Publication date
GR3024875T3 (en) 1998-01-30
JPH08505838A (ja) 1996-06-25
DK0667864T3 (da) 1998-05-04
WO1994011354A1 (en) 1994-05-26
ZA937756B (en) 1994-05-11
DE69314183D1 (de) 1997-10-30
AU5376094A (en) 1994-06-08
ES2107688T3 (es) 1997-12-01
EP0667864A1 (en) 1995-08-23
EP0667864B1 (en) 1997-09-24
JP3271667B2 (ja) 2002-04-02
DE69314183T2 (de) 1998-01-15
ATE158578T1 (de) 1997-10-15
GB9223352D0 (en) 1992-12-23
US5789417A (en) 1998-08-04

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