DE69310484D1 - Pulverförmige, stabilisierte Wirkstoffe, diese enthaltende Zusammensetzungen Verfahren zu ihrer Herstellung und ihre Verwendung - Google Patents

Pulverförmige, stabilisierte Wirkstoffe, diese enthaltende Zusammensetzungen Verfahren zu ihrer Herstellung und ihre Verwendung

Info

Publication number
DE69310484D1
DE69310484D1 DE69310484T DE69310484T DE69310484D1 DE 69310484 D1 DE69310484 D1 DE 69310484D1 DE 69310484 T DE69310484 T DE 69310484T DE 69310484 T DE69310484 T DE 69310484T DE 69310484 D1 DE69310484 D1 DE 69310484D1
Authority
DE
Germany
Prior art keywords
cellulose
stabilised
active agents
agent
vinylpyrrolidone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69310484T
Other languages
English (en)
Other versions
DE69310484T2 (de
Inventor
Guy Derrieu
Bernard Raynier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Virbac SA
Original Assignee
Laboratoires Virbac SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9436026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69310484(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Laboratoires Virbac SA filed Critical Laboratoires Virbac SA
Publication of DE69310484D1 publication Critical patent/DE69310484D1/de
Application granted granted Critical
Publication of DE69310484T2 publication Critical patent/DE69310484T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/04Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/70Fixation, conservation, or encapsulation of flavouring agents
    • A23L27/74Fixation, conservation, or encapsulation of flavouring agents with a synthetic polymer matrix or excipient, e.g. vinylic, acrylic polymers
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/30Encapsulation of particles, e.g. foodstuff additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • A61K8/8182Copolymers of vinyl-pyrrolidones. Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/412Microsized, i.e. having sizes between 0.1 and 100 microns
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60Particulates further characterized by their structure or composition
    • A61K2800/61Surface treated
    • A61K2800/62Coated
    • A61K2800/624Coated by macromolecular compounds
DE69310484T 1992-11-30 1993-11-29 Pulverförmige, stabilisierte Wirkstoffe, diese enthaltende Zusammensetzungen Verfahren zu ihrer Herstellung und ihre Verwendung Revoked DE69310484T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214365A FR2698560B1 (fr) 1992-11-30 1992-11-30 Principes actifs pulvérulents stabilisés, compositions les contenant, leur procédé d'obtention et leurs applications.

Publications (2)

Publication Number Publication Date
DE69310484D1 true DE69310484D1 (de) 1997-06-12
DE69310484T2 DE69310484T2 (de) 1997-12-11

Family

ID=9436026

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69310484T Revoked DE69310484T2 (de) 1992-11-30 1993-11-29 Pulverförmige, stabilisierte Wirkstoffe, diese enthaltende Zusammensetzungen Verfahren zu ihrer Herstellung und ihre Verwendung
DE0600775T Pending DE600775T1 (de) 1992-11-30 1993-11-29 Pulverförmige, stabilisierte Wirkstoffe, diese enthaltende Zusammensetzungen Verfahren zu ihrer Herstellung und ihre Verwendung.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE0600775T Pending DE600775T1 (de) 1992-11-30 1993-11-29 Pulverförmige, stabilisierte Wirkstoffe, diese enthaltende Zusammensetzungen Verfahren zu ihrer Herstellung und ihre Verwendung.

Country Status (13)

Country Link
US (1) US5595762A (de)
EP (1) EP0600775B1 (de)
JP (1) JPH06292825A (de)
AT (1) ATE152617T1 (de)
AU (1) AU667588B2 (de)
CA (1) CA2110370C (de)
DE (2) DE69310484T2 (de)
DK (1) DK0600775T3 (de)
ES (1) ES2060563T3 (de)
FR (1) FR2698560B1 (de)
GR (2) GR940300063T1 (de)
NZ (1) NZ250331A (de)
ZA (1) ZA938938B (de)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6149953A (en) * 1993-11-08 2000-11-21 Delta Food Group, Inc. Seeded microcapsules
US6524832B1 (en) 1994-02-04 2003-02-25 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
IT1270216B (it) * 1994-06-14 1997-04-29 Recordati Chem Pharm Metodo di stabilizzazione di composti biologicamente attivi mediante microgranuli ricoperti sospendibili in fluidi alimentari
US5492947A (en) 1994-06-23 1996-02-20 Aspen Research Corporation Barrier material comprising a thermoplastic and a compatible cyclodextrin derivative
US5985772A (en) 1994-06-23 1999-11-16 Cellresin Technologies, Llc Packaging system comprising cellulosic web with a permeant barrier or contaminant trap
FR2733423B1 (fr) * 1995-04-26 1997-06-20 Virbac Lab Compositions pulverulentes et solubles dans l'eau et leurs applications
FR2737134B1 (fr) * 1995-07-27 1998-05-29 Bionatec Sarl Procede de fabrication de granules et granules ainsi obtenus
US5882565A (en) 1995-12-11 1999-03-16 Cellresin Technologies, Llc Barrier material comprising a thermoplastic and a compatible cyclodextrin derivative
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
FR2748393B1 (fr) * 1996-05-10 1998-09-11 Sogeval Lab Procede de traitement de principes actifs pulverulents et melange notamment aliment pour animaux renfermant des principes actifs ainsi traites
AU7706598A (en) * 1997-05-30 1998-12-30 Laboratorios Phoenix U.S.A., Inc. Multi-layered osmotic device
US6022554A (en) * 1997-12-15 2000-02-08 American Home Products Corporation Polymeric microporous film coated subcutaneous implant
US6632455B2 (en) * 1997-12-22 2003-10-14 Schering Corporation Molecular dispersion composition with enhanced bioavailability
JP2000016940A (ja) * 1998-04-28 2000-01-18 Takeda Chem Ind Ltd ビタミンb▲12▼類含有組成物
WO2000006685A1 (en) * 1998-07-29 2000-02-10 The Procter & Gamble Company Particulate compositions having a plasma-induced, water-soluble coating and process for making same
US6440918B1 (en) 1998-07-29 2002-08-27 The Procter & Gamble Company Particulate compositions having a plasma-induced, graft polymerized, water-soluble coating and process for making same
EP1100860A1 (de) 1998-07-29 2001-05-23 The Procter & Gamble Company Waschmittelzusammensetzungen mit plasmainduzierten wasserlöslichen beschichtungen und verfahren zu deren herstellung
ATE386546T1 (de) * 1998-08-04 2008-03-15 Takeda Schering Plough Animal Stabilisierte ölige zubereitung von tobicillin (beta-lactam-antibiotika)
US20080213378A1 (en) * 1998-10-01 2008-09-04 Elan Pharma International, Ltd. Nanoparticulate statin formulations and novel statin combinations
US8293277B2 (en) * 1998-10-01 2012-10-23 Alkermes Pharma Ireland Limited Controlled-release nanoparticulate compositions
EP2266542A3 (de) * 1998-10-01 2013-07-31 Elan Pharma International Limited Nanopartikelformulierungen mit kontrollierter Wirkstofffreisetzung
US8236352B2 (en) * 1998-10-01 2012-08-07 Alkermes Pharma Ireland Limited Glipizide compositions
US20040013613A1 (en) * 2001-05-18 2004-01-22 Jain Rajeev A Rapidly disintegrating solid oral dosage form
US20040141925A1 (en) * 1998-11-12 2004-07-22 Elan Pharma International Ltd. Novel triamcinolone compositions
US6969529B2 (en) * 2000-09-21 2005-11-29 Elan Pharma International Ltd. Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
US7521068B2 (en) * 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
US6428814B1 (en) * 1999-10-08 2002-08-06 Elan Pharma International Ltd. Bioadhesive nanoparticulate compositions having cationic surface stabilizers
US20040258763A1 (en) * 1999-02-03 2004-12-23 Bell Steve J.D. Methods of manufacture and use of calcium phosphate particles containing allergens
EP1471034A3 (de) * 1999-02-03 2005-03-02 Biosante Pharmaceuticals, Inc. Therapeutische kalzium-phosphat Partikel und Methoden zu deren Herstellung und Verwendung
CA2361421A1 (en) * 1999-02-03 2000-08-10 Biosante Pharmaceuticals, Inc. Therapeutic calcium phosphate particles and methods of manufacture and use
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6316462B1 (en) 1999-04-09 2001-11-13 Schering Corporation Methods of inducing cancer cell death and tumor regression
US20040115134A1 (en) * 1999-06-22 2004-06-17 Elan Pharma International Ltd. Novel nifedipine compositions
US6448323B1 (en) * 1999-07-09 2002-09-10 Bpsi Holdings, Inc. Film coatings and film coating compositions based on polyvinyl alcohol
US6500462B1 (en) * 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
CN1189159C (zh) 2000-05-05 2005-02-16 欧莱雅 含水溶性美容活性组分水性核的微胶囊及含其的组合物
US20040156872A1 (en) * 2000-05-18 2004-08-12 Elan Pharma International Ltd. Novel nimesulide compositions
US7198795B2 (en) 2000-09-21 2007-04-03 Elan Pharma International Ltd. In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions
DE60142305D1 (de) * 2000-11-17 2010-07-15 Takeda Pharmaceutical Pharmazeutische zubereitung enthaltend n-ä2-(1,6,7,8-tetrahydro-2h-indenoä5,4 büfuran-8-yl)ethylüpropionamid ummantelt mit einer copolyvidon-enthaltenden, polyäthylenglykolfreien umhüllung
ATE419834T1 (de) * 2000-11-20 2009-01-15 Elan Pharma Int Ltd Nanopartikel bestehend aus einem arzneistoff und copolymeren von vinyl pyrrolidon und vinyl acetat als oberflächenstabilisatoren
JP2004531467A (ja) 2000-11-28 2004-10-14 エフ エム シー コーポレーション 可食性pga被覆組成物
US6932861B2 (en) * 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
MXPA03009588A (es) 2001-04-18 2004-12-06 Nostrum Pharmaceuticals Inc Un recubrimiento novedoso para una composicion farmaceutica de liberacion sostenida.
US20030185892A1 (en) * 2001-08-17 2003-10-02 Bell Steve J. D. Intraocular delivery compositions and methods
US20040101566A1 (en) * 2002-02-04 2004-05-27 Elan Pharma International Limited Novel benzoyl peroxide compositions
AU2003210517A1 (en) * 2002-02-04 2003-09-02 Elan Pharma International, Ltd. Drug nanoparticles with lysozyme surface stabiliser
EP1490030B2 (de) * 2002-03-20 2010-07-14 Elan Pharma International Limited Nanopartikelzusammensetzungen von angiogeneseinhibitoren
JP4776229B2 (ja) * 2002-07-16 2011-09-21 エラン ファーマ インターナショナル,リミティド 安定なナノ粒子活性物質の液体投与組成物
US8487002B2 (en) * 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
TWI319713B (en) * 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
EP2112920B1 (de) 2003-06-26 2018-07-25 Intellipharmaceutics Corp. Protonenpumpeninhibitoren enthaltende kapseln, die verschieden aufgebaute untereinheiten zur verzögerten wirkstofffreisetzung enthalten
US7416525B2 (en) * 2003-09-18 2008-08-26 Myrakelle, Llc Rotary blood pump
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
BRPI0507680A (pt) * 2004-02-13 2007-07-17 Nod Pharmaceuticals Inc partìculas de fosfato de cálcio terapêuticas e métodos de fabricação e uso das mesmas
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
JP2006045491A (ja) * 2004-07-01 2006-02-16 Erubu:Kk 機能性材料、機能性材料の製造方法並びにその機能性材料を用いた、機能性部材及び環境改質装置
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US20060105039A1 (en) * 2004-10-21 2006-05-18 Jin-Wang Lai Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
JP2008518956A (ja) * 2004-11-01 2008-06-05 バイオサンテ ファーマシューティカルズ,インコーポレイティド 化粧又は美容薬品のための使用における治療用リン酸カルシウム、及び製造方法、及び使用
BRPI0615860B8 (pt) * 2005-09-09 2021-05-25 Labopharm Barbados Ltd composição farmacêutica de liberação prolongada monolítica sólida
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
JP2009532131A (ja) 2006-03-31 2009-09-10 オーキス メディカル コーポレイション 回転血液ポンプ
CN101453993A (zh) * 2006-04-03 2009-06-10 伊萨·奥迪迪 含有机溶胶涂层的受控释放递送物件
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
DE102006026965A1 (de) * 2006-06-09 2007-12-13 Omya Development Ag Komposits aus anorganischen und/oder organischen Mikropartikeln und Nano-Calciumcarbonatpartikeln
FR2918990B1 (fr) * 2007-07-20 2012-12-21 Innov Ia Procede de preparation de compositions pulverulentes stables
JP5171953B2 (ja) 2008-06-23 2013-03-27 テルモ株式会社 血液ポンプ装置
CN102105140B (zh) * 2008-07-02 2013-10-23 巴斯夫欧洲公司 涂覆片剂的方法
US9067005B2 (en) 2008-12-08 2015-06-30 Thoratec Corporation Centrifugal pump apparatus
JP5378010B2 (ja) 2009-03-05 2013-12-25 ソラテック コーポレーション 遠心式ポンプ装置
CN102341600B (zh) 2009-03-06 2014-12-10 胸腔科技有限公司 离心式泵装置
BRPI1001091A2 (pt) * 2009-04-22 2011-03-22 Dr Suwelack Skin & Health Care Ag artigo moldado revestido secado por congelamento
WO2011013483A1 (ja) 2009-07-29 2011-02-03 Ntn株式会社 回転駆動装置およびそれを用いた遠心式ポンプ装置
WO2011025035A1 (ja) * 2009-08-31 2011-03-03 日新化成株式会社 コーティング用組成物
JP5443197B2 (ja) 2010-02-16 2014-03-19 ソラテック コーポレーション 遠心式ポンプ装置
JP5572832B2 (ja) 2010-03-26 2014-08-20 ソーラテック コーポレイション 遠心式血液ポンプ装置
JP5681403B2 (ja) 2010-07-12 2015-03-11 ソーラテック コーポレイション 遠心式ポンプ装置
JP5577506B2 (ja) 2010-09-14 2014-08-27 ソーラテック コーポレイション 遠心式ポンプ装置
JP5704906B2 (ja) * 2010-12-02 2015-04-22 花王株式会社 固形粉末化粧料表面における文字や模様の形成方法
EP2693609B1 (de) 2011-03-28 2017-05-03 Thoratec Corporation Dreh- und antriebsvorrichtung und zentrifugalpumpvorrichtung damit
JP6083929B2 (ja) 2012-01-18 2017-02-22 ソーラテック コーポレイション 遠心式ポンプ装置
EP2916828A1 (de) * 2012-11-07 2015-09-16 Nazura Biohealth Inc. Enterale gras-beschichtungsformulierungen sowie verfahren zur herstellung und verwendung davon
US9371826B2 (en) 2013-01-24 2016-06-21 Thoratec Corporation Impeller position compensation using field oriented control
US9556873B2 (en) 2013-02-27 2017-01-31 Tc1 Llc Startup sequence for centrifugal pump with levitated impeller
US9713663B2 (en) 2013-04-30 2017-07-25 Tc1 Llc Cardiac pump with speed adapted for ventricle unloading
US10052420B2 (en) 2013-04-30 2018-08-21 Tc1 Llc Heart beat identification and pump speed synchronization
US9623161B2 (en) 2014-08-26 2017-04-18 Tc1 Llc Blood pump and method of suction detection
EP3240842B1 (de) 2015-01-01 2023-05-03 Ideal Cures Pvt. Ltd. Neuartige filmbeschichtungszusammensetzung
WO2016130846A1 (en) 2015-02-11 2016-08-18 Thoratec Corporation Heart beat identification and pump speed synchronization
US10166318B2 (en) 2015-02-12 2019-01-01 Tc1 Llc System and method for controlling the position of a levitated rotor
US10371152B2 (en) 2015-02-12 2019-08-06 Tc1 Llc Alternating pump gaps
EP3256184B1 (de) 2015-02-13 2020-04-08 Tc1 Llc Laufradaufhängungsmechanismus für herzpumpe
TW202337463A (zh) * 2015-06-30 2023-10-01 美商建南德克公司 含藥物之立即釋放錠劑及形成該錠劑的方法
US10117983B2 (en) 2015-11-16 2018-11-06 Tc1 Llc Pressure/flow characteristic modification of a centrifugal pump in a ventricular assist device
CN113200974A (zh) * 2021-04-30 2021-08-03 衢州伟荣药化有限公司 药物组合物、盐酸呋喃它酮及其制备方法和应用方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5316384B2 (de) * 1973-05-02 1978-05-31
DE2903778C2 (de) * 1979-02-01 1982-06-03 Ludwig Heumann & Co GmbH, 8500 Nürnberg Verwendung von Hydroxypropylmethylcellulose zum Überziehen von den pharmazeutischen Wirkstoff in der Hülle enthaltenden Weichgelatine-Buccalkapseln
FR2539626B2 (fr) * 1983-01-25 1985-06-21 Lafon Labor Nouveau procede de preparation de formes galeniques utiles notamment en therapeutique, dietetique, cosmetique et diagnostic, et formes obtenues selon ce procede
FR2548675B1 (fr) * 1983-07-06 1987-01-09 Seppic Sa Compositions filmogenes pour enrobage des formes solides de produits pharmaceutiques ou alimentaires et produits obtenus revetus desdites compositions
GB8322007D0 (en) * 1983-08-16 1983-09-21 Wellcome Found Pharmaceutical delivery system
US4769027A (en) * 1984-08-15 1988-09-06 Burroughs Wellcome Co. Delivery system
GB8707421D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
JPS63258809A (ja) * 1987-04-16 1988-10-26 Towa Yakuhin Kk 医薬活性成分の放出性にすぐれ、かつ苦味を隠蔽した細粒剤
AU608891B2 (en) * 1987-09-24 1991-04-18 Merck & Co., Inc. Solubility modulated drug delivery device
JPH01106817A (ja) * 1987-10-21 1989-04-24 Kiteii:Kk 多孔質内封入体及びその製造方法
US5178868A (en) * 1988-10-26 1993-01-12 Kabi Pharmacia Aktiebolaq Dosage form
FR2657255B1 (fr) * 1989-12-27 1992-04-24 Sederma Sa Description de preparations cosmetiques originales dont les principes actifs sont pieges dans un reseau polymerique greffe a la surface de particules de silice.

Also Published As

Publication number Publication date
DE600775T1 (de) 1995-04-06
ES2060563T3 (es) 1997-09-16
CA2110370A1 (en) 1994-05-31
ATE152617T1 (de) 1997-05-15
NZ250331A (en) 1997-05-26
JPH06292825A (ja) 1994-10-21
AU5197193A (en) 1994-06-09
AU667588B2 (en) 1996-03-28
GR940300063T1 (en) 1994-09-30
DK0600775T3 (da) 1997-10-13
FR2698560B1 (fr) 1995-02-03
US5595762A (en) 1997-01-21
ES2060563T1 (es) 1994-12-01
DE69310484T2 (de) 1997-12-11
EP0600775B1 (de) 1997-05-07
FR2698560A1 (fr) 1994-06-03
CA2110370C (en) 2009-09-22
ZA938938B (en) 1994-09-28
EP0600775A1 (de) 1994-06-08
GR3024231T3 (en) 1997-10-31

Similar Documents

Publication Publication Date Title
DE69310484D1 (de) Pulverförmige, stabilisierte Wirkstoffe, diese enthaltende Zusammensetzungen Verfahren zu ihrer Herstellung und ihre Verwendung
CA1331342C (en) Compressed-molded preparations
KR100348842B1 (ko) 염기성물질로안정화된약제학적조성물
CA1069826A (en) Slowly neutralized solid cleaning denture composition
US4704284A (en) Long-acting matrix tablet formulations
IL111647A0 (en) Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles, their preparation and pharmaceutical compositions containing them
MX9206952A (es) Polvo de dispercion redispersable a partir de un copolimerizado de acetato de vinilo de n-vinilpirrolidona su preparcion y su empleo
JPS62120316A (ja) 薬剤の放出が調節された錠剤型組成物
KR880010759A (ko) 방출 조절성 제제
IL92994A (en) Pharmaceutical preparations for immediate release and delayed release containing gampibrozil
KR930001899A (ko) 서방성 제제
AU546449B2 (en) Medicated elastic liquid plasters
AU3394689A (en) Pharmaceutical compositions
US4267138A (en) Coating ensuring a controlled release of active ingredients of biologically active compositions, particularly pharmaceutical compositions and a process for preparation of biologically active compositions ensuring controlled release of active ingredients
CA2163218A1 (en) New macrophages, process for preparing the same and their use as active substances of pharmaceutical compositions
NO996049L (no) Farmasoeytisk preparat med kontrollert frigjoering, med ACE- inhibitor som aktiv ingrediens
DE4124409B4 (de) Pharmazeutische Zubereitungen
US5587145A (en) Aqueous aerosol lacquer for setting hair
HUP9900856A2 (hu) Lúgosító káliumsót magában foglaló szabályozott hatóanyag-leadású készítmények
KR900701255A (ko) 서방성 딜티아젬 제제
US20030215509A1 (en) Coated sustained release tablets of a hygroscopic compound for once-a-day therapy
CA1248524A (en) Complexes of prostaglandins
KR950016748A (ko) 니세르골린을 함유하는 방출-조절성 약제학적 조성물
KR900000286A (ko) 안정화된 미립자 과산화수소 첨가제 및 그의 용도
JPH07503036A (ja) エマルジョングラフト共重合体の化粧品,医薬品組成物用のフィルム形成剤としての利用,及びエマルジョングラフト共重合体の製造方法

Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation