DE69309714T2 - Kondensierte benzo(d)isoxazol-derivate und ihre verwendung als psychoaktive mittel - Google Patents

Kondensierte benzo(d)isoxazol-derivate und ihre verwendung als psychoaktive mittel

Info

Publication number
DE69309714T2
DE69309714T2 DE69309714T DE69309714T DE69309714T2 DE 69309714 T2 DE69309714 T2 DE 69309714T2 DE 69309714 T DE69309714 T DE 69309714T DE 69309714 T DE69309714 T DE 69309714T DE 69309714 T2 DE69309714 T2 DE 69309714T2
Authority
DE
Germany
Prior art keywords
pct
hydrogen
date jul
represent
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69309714T
Other languages
English (en)
Other versions
DE69309714D1 (de
Inventor
Edwardandrew Boyd
Brenda Costall
Mary Elizabeth Kelly
Philip James Parsons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
British Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Technology Group Ltd filed Critical British Technology Group Ltd
Publication of DE69309714D1 publication Critical patent/DE69309714D1/de
Application granted granted Critical
Publication of DE69309714T2 publication Critical patent/DE69309714T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69309714T 1992-12-23 1993-12-07 Kondensierte benzo(d)isoxazol-derivate und ihre verwendung als psychoaktive mittel Expired - Lifetime DE69309714T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929226857A GB9226857D0 (en) 1992-12-23 1992-12-23 Pharmaceutical compositions
PCT/GB1993/002501 WO1994014816A1 (en) 1992-12-23 1993-12-07 Condensed benzo(d)isoxazole derivatives and their use as psychoactive agents

Publications (2)

Publication Number Publication Date
DE69309714D1 DE69309714D1 (de) 1997-05-15
DE69309714T2 true DE69309714T2 (de) 1997-08-21

Family

ID=10727141

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69309714T Expired - Lifetime DE69309714T2 (de) 1992-12-23 1993-12-07 Kondensierte benzo(d)isoxazol-derivate und ihre verwendung als psychoaktive mittel

Country Status (15)

Country Link
US (1) US5707988A (de)
EP (1) EP0675890B1 (de)
JP (1) JP3542803B2 (de)
KR (1) KR100320996B1 (de)
AT (1) ATE151427T1 (de)
AU (1) AU680645B2 (de)
CA (1) CA2152284C (de)
DE (1) DE69309714T2 (de)
DK (1) DK0675890T3 (de)
ES (1) ES2101483T3 (de)
GB (2) GB9226857D0 (de)
GR (1) GR3023744T3 (de)
IL (1) IL108135A (de)
WO (1) WO1994014816A1 (de)
ZA (1) ZA939665B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0313628D0 (en) * 2003-06-12 2003-07-16 Btg Int Ltd Psychoactive compounds
EP1631557B1 (de) * 2003-06-12 2006-12-20 Btg International Limited Cyclische hydroxylamine als psychoactive verbindugen
TW201020233A (en) * 2008-10-09 2010-06-01 Kyorin Seiyaku Kk Isoquinoline derivative, and pde inhibitor comprising same as active ingredient

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1540580A (en) * 1975-09-02 1979-02-14 Shell Int Research Fungicidal isoxazolidines
US4411901A (en) * 1981-12-23 1983-10-25 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US5049564A (en) * 1989-11-17 1991-09-17 Abbott Laboratories 5-HT selective agents
JP3042876B2 (ja) * 1989-05-24 2000-05-22 バイオサーフイス・フアーマ・アクチエボラーグ 置換されたイソキサゾリジンおよびイソキサゾリン
US5114936A (en) * 1990-08-23 1992-05-19 Hoechst-Roussel Pharmaceuticals Incorporated 6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5h)-ones and -ols, compositions and pharmaceutical use
GB2264299B (en) * 1992-02-19 1995-07-26 British Tech Group Iso-oxazolidine derivatives

Also Published As

Publication number Publication date
JP3542803B2 (ja) 2004-07-14
GB9226857D0 (en) 1993-02-17
CA2152284C (en) 2006-01-17
DE69309714D1 (de) 1997-05-15
AU680645B2 (en) 1997-08-07
ZA939665B (en) 1995-06-23
GR3023744T3 (en) 1997-09-30
GB2273706B (en) 1996-06-05
KR960700249A (ko) 1996-01-19
GB2273706A (en) 1994-06-29
IL108135A0 (en) 1994-08-26
ATE151427T1 (de) 1997-04-15
EP0675890A1 (de) 1995-10-11
DK0675890T3 (da) 1997-05-05
IL108135A (en) 1998-04-05
ES2101483T3 (es) 1997-07-01
JPH08504796A (ja) 1996-05-21
US5707988A (en) 1998-01-13
CA2152284A1 (en) 1994-07-07
WO1994014816A1 (en) 1994-07-07
KR100320996B1 (ko) 2002-07-27
AU5573394A (en) 1994-07-19
EP0675890B1 (de) 1997-04-09
GB9325044D0 (en) 1994-02-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BTG INTERNATIONAL LTD., LONDON, GB