ATE169010T1 - Benzisoxazol-derivate und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Benzisoxazol-derivate und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number
ATE169010T1
ATE169010T1 AT93904218T AT93904218T ATE169010T1 AT E169010 T1 ATE169010 T1 AT E169010T1 AT 93904218 T AT93904218 T AT 93904218T AT 93904218 T AT93904218 T AT 93904218T AT E169010 T1 ATE169010 T1 AT E169010T1
Authority
AT
Austria
Prior art keywords
group
substituted
hydrogen
represents hydrogen
halogeno
Prior art date
Application number
AT93904218T
Other languages
English (en)
Inventor
Edward Andrew Boyd
Brenda Costall
Elizabeth Mary Kelly
Philip James Parsons
Original Assignee
British Tech Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929203500A external-priority patent/GB9203500D0/en
Application filed by British Tech Group filed Critical British Tech Group
Application granted granted Critical
Publication of ATE169010T1 publication Critical patent/ATE169010T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT93904218T 1992-02-19 1993-02-18 Benzisoxazol-derivate und diese enthaltende pharmazeutische zusammensetzungen ATE169010T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929203500A GB9203500D0 (en) 1992-02-19 1992-02-19 Pharmaceutical compositions
GB9300921A GB2264299B (en) 1992-02-19 1993-01-19 Iso-oxazolidine derivatives

Publications (1)

Publication Number Publication Date
ATE169010T1 true ATE169010T1 (de) 1998-08-15

Family

ID=26300339

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93904218T ATE169010T1 (de) 1992-02-19 1993-02-18 Benzisoxazol-derivate und diese enthaltende pharmazeutische zusammensetzungen

Country Status (16)

Country Link
US (2) US5476867A (de)
EP (1) EP0626951B1 (de)
JP (1) JP3464479B2 (de)
KR (1) KR100274479B1 (de)
AT (1) ATE169010T1 (de)
AU (1) AU677176B2 (de)
CA (1) CA2117471C (de)
DE (1) DE69320030T2 (de)
DK (1) DK0626951T3 (de)
ES (1) ES2121075T3 (de)
GB (1) GB2264299B (de)
IL (1) IL104771A (de)
NO (1) NO305027B1 (de)
PH (1) PH31392A (de)
WO (1) WO1993017004A1 (de)
ZA (1) ZA931190B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9226857D0 (en) * 1992-12-23 1993-02-17 Boyd Edward A Pharmaceutical compositions
US7115666B2 (en) * 2002-10-15 2006-10-03 Renovis, Inc. Nitrone compounds, pharmaceutical compositions containing the same and methods for treating inflammation and neuropathic pain
ES2278321T3 (es) * 2003-06-12 2007-08-01 Btg International Limited Hidroxilamina ciclica como compuestos psicoactivos.
ITMI20062102A1 (it) * 2006-11-02 2008-05-03 Abiogen Pharma Spa Nuovui sali di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidrobenzo-d-isossazol-4-one
EP2112142A1 (de) 2008-04-24 2009-10-28 Abiogen Pharma S.p.A. Verfahren zur Herstellung eines kristallinen Formverbundstoffs aus 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-on
ITMI20080768A1 (it) * 2008-04-24 2009-10-25 Abiogen Pharma Spa Procedimento per la preparazione di un composto in forma cristallina di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidro-benzo[d]isossazol-4-one
WO2011010332A1 (en) * 2009-07-23 2011-01-27 Abiogen Pharma S.P.A. Process for preparing rel-(3r*,3as*,7as*)-3-benzyl-2-methyl-2,3, 3a,4,5,6,7,7a- octahydrobenzo[d]isoxazoi-4-one or a salt thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1540580A (en) * 1975-09-02 1979-02-14 Shell Int Research Fungicidal isoxazolidines
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US5049564A (en) * 1989-11-17 1991-09-17 Abbott Laboratories 5-HT selective agents
US5114960A (en) * 1989-07-20 1992-05-19 Hoffmann-La Roche Inc. Substituted isoxazole derivatives
US5114936A (en) * 1990-08-23 1992-05-19 Hoechst-Roussel Pharmaceuticals Incorporated 6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5h)-ones and -ols, compositions and pharmaceutical use

Also Published As

Publication number Publication date
DE69320030D1 (de) 1998-09-03
DE69320030T2 (de) 1998-12-10
EP0626951B1 (de) 1998-07-29
CA2117471A1 (en) 1993-09-02
KR950700264A (ko) 1995-01-16
NO943042L (no) 1994-08-17
EP0626951A1 (de) 1994-12-07
CA2117471C (en) 2003-04-22
ZA931190B (en) 1994-08-19
US5578626A (en) 1996-11-26
NO305027B1 (no) 1999-03-22
IL104771A0 (en) 1994-05-30
JP3464479B2 (ja) 2003-11-10
PH31392A (en) 1998-10-29
JPH07504181A (ja) 1995-05-11
US5476867A (en) 1995-12-19
DK0626951T3 (da) 1999-02-15
NO943042D0 (no) 1994-08-17
AU3508693A (en) 1993-09-13
IL104771A (en) 1998-07-15
GB9300921D0 (en) 1993-03-10
KR100274479B1 (ko) 2000-12-15
GB2264299A (en) 1993-08-25
ES2121075T3 (es) 1998-11-16
AU677176B2 (en) 1997-04-17
WO1993017004A1 (en) 1993-09-02
GB2264299B (en) 1995-07-26

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification