ATE109475T1 - Benzothiazolinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. - Google Patents
Benzothiazolinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.Info
- Publication number
- ATE109475T1 ATE109475T1 AT91910896T AT91910896T ATE109475T1 AT E109475 T1 ATE109475 T1 AT E109475T1 AT 91910896 T AT91910896 T AT 91910896T AT 91910896 T AT91910896 T AT 91910896T AT E109475 T1 ATE109475 T1 AT E109475T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- radical
- manufacture
- date dec
- benzothiazole derivatives
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical class C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052757 nitrogen Chemical group 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9007068A FR2663029B1 (fr) | 1990-06-07 | 1990-06-07 | Derives de benzothiazole, leur preparation et les medicaments les contenant. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE109475T1 true ATE109475T1 (de) | 1994-08-15 |
Family
ID=9397359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91910896T ATE109475T1 (de) | 1990-06-07 | 1991-05-31 | Benzothiazolinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5340824A (de) |
| EP (1) | EP0532602B1 (de) |
| JP (1) | JPH05507918A (de) |
| AT (1) | ATE109475T1 (de) |
| CA (1) | CA2080005A1 (de) |
| DE (1) | DE69103271T2 (de) |
| DK (1) | DK0532602T3 (de) |
| ES (1) | ES2057901T3 (de) |
| FR (1) | FR2663029B1 (de) |
| WO (1) | WO1991018892A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2688138B1 (fr) * | 1992-03-06 | 1995-05-05 | Rhone Poulenc Rorer Sa | Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique. |
| DE4310523A1 (de) * | 1993-03-31 | 1994-10-06 | Basf Ag | Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen |
| US6017903A (en) | 1996-09-27 | 2000-01-25 | Guilford Pharmaceuticals Inc. | Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors |
| US5824662A (en) | 1996-09-27 | 1998-10-20 | Guilford Pharmaceuticals Inc. | Treatment of global and focal ischemia using naaladase inhibitors |
| KR20000036227A (ko) | 1996-09-27 | 2000-06-26 | 토마스 씨. 서 | 날라다아제조성물, 글루탐산염 이상 치료법 및 동물내의 뉴우런활성법 |
| EP1043319B1 (de) * | 1997-11-05 | 2005-03-16 | Mitsubishi Chemical Corporation | Alkylaminoderivate |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2492258A1 (fr) * | 1980-10-17 | 1982-04-23 | Pharmindustrie | Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole |
| GB8820231D0 (en) * | 1988-08-25 | 1988-09-28 | Fujisawa Pharmaceutical Co | New benzazole compounds processes for preparation thereof & pharmaceutical composition comprising same |
| FR2649701B2 (fr) * | 1988-12-15 | 1991-11-22 | Rhone Poulenc Sante | Derives d'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant |
| EP0375510B1 (de) * | 1988-12-15 | 1992-11-11 | Rhone-Poulenc Sante | 2-Imino-6-polyfluoralkoxy-benzothiazol-Derivate, Verfahren zu deren Herstellung und Arzneimittel, die sie enthalten |
-
1990
- 1990-06-07 FR FR9007068A patent/FR2663029B1/fr not_active Expired - Lifetime
-
1991
- 1991-05-31 JP JP91510727A patent/JPH05507918A/ja active Pending
- 1991-05-31 DK DK91910896.9T patent/DK0532602T3/da active
- 1991-05-31 DE DE69103271T patent/DE69103271T2/de not_active Expired - Fee Related
- 1991-05-31 ES ES91910896T patent/ES2057901T3/es not_active Expired - Lifetime
- 1991-05-31 AT AT91910896T patent/ATE109475T1/de active
- 1991-05-31 WO PCT/FR1991/000437 patent/WO1991018892A1/fr not_active Ceased
- 1991-05-31 US US07/938,153 patent/US5340824A/en not_active Expired - Fee Related
- 1991-05-31 CA CA002080005A patent/CA2080005A1/fr not_active Abandoned
- 1991-05-31 EP EP91910896A patent/EP0532602B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69103271D1 (de) | 1994-09-08 |
| ES2057901T3 (es) | 1994-10-16 |
| FR2663029B1 (fr) | 1992-07-31 |
| WO1991018892A1 (fr) | 1991-12-12 |
| EP0532602B1 (de) | 1994-08-03 |
| FR2663029A1 (fr) | 1991-12-13 |
| US5340824A (en) | 1994-08-23 |
| CA2080005A1 (fr) | 1991-12-08 |
| DE69103271T2 (de) | 1994-12-22 |
| DK0532602T3 (da) | 1994-09-12 |
| EP0532602A1 (de) | 1993-03-24 |
| JPH05507918A (ja) | 1993-11-11 |
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