DE69103271D1 - Benzothiazolinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. - Google Patents

Benzothiazolinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.

Info

Publication number
DE69103271D1
DE69103271D1 DE69103271T DE69103271T DE69103271D1 DE 69103271 D1 DE69103271 D1 DE 69103271D1 DE 69103271 T DE69103271 T DE 69103271T DE 69103271 T DE69103271 T DE 69103271T DE 69103271 D1 DE69103271 D1 DE 69103271D1
Authority
DE
Germany
Prior art keywords
pct
production
radical
same
products containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69103271T
Other languages
English (en)
Other versions
DE69103271T2 (de
Inventor
Claude Gueremy
Patrick Jimonet
Serge Mignani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Application granted granted Critical
Publication of DE69103271D1 publication Critical patent/DE69103271D1/de
Publication of DE69103271T2 publication Critical patent/DE69103271T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69103271T 1990-06-07 1991-05-31 Benzothiazolinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. Expired - Fee Related DE69103271T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9007068A FR2663029B1 (fr) 1990-06-07 1990-06-07 Derives de benzothiazole, leur preparation et les medicaments les contenant.
PCT/FR1991/000437 WO1991018892A1 (fr) 1990-06-07 1991-05-31 Derives de benzothiazole, leur preparation et les medicaments les contenant

Publications (2)

Publication Number Publication Date
DE69103271D1 true DE69103271D1 (de) 1994-09-08
DE69103271T2 DE69103271T2 (de) 1994-12-22

Family

ID=9397359

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69103271T Expired - Fee Related DE69103271T2 (de) 1990-06-07 1991-05-31 Benzothiazolinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.

Country Status (10)

Country Link
US (1) US5340824A (de)
EP (1) EP0532602B1 (de)
JP (1) JPH05507918A (de)
AT (1) ATE109475T1 (de)
CA (1) CA2080005A1 (de)
DE (1) DE69103271T2 (de)
DK (1) DK0532602T3 (de)
ES (1) ES2057901T3 (de)
FR (1) FR2663029B1 (de)
WO (1) WO1991018892A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2688138B1 (fr) * 1992-03-06 1995-05-05 Rhone Poulenc Rorer Sa Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique.
DE4310523A1 (de) * 1993-03-31 1994-10-06 Basf Ag Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) * 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
CZ60499A3 (cs) 1996-09-27 1999-08-11 Guilford Pharmaceuticals Inc. Prostředky s účinkem na NAALADázy, způsoby léčení glutamátové abnormality a způsoby ovlivňování neuronální aktivity u živočichů
ATE291015T1 (de) * 1997-11-05 2005-04-15 Mitsubishi Chem Corp Alkylaminoderivate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
GB8820231D0 (en) * 1988-08-25 1988-09-28 Fujisawa Pharmaceutical Co New benzazole compounds processes for preparation thereof & pharmaceutical composition comprising same
DE68903484T2 (de) * 1988-12-15 1993-03-18 Rhone Poulenc Sante 2-imino-6-polyfluoralkoxy-benzothiazol-derivate, verfahren zu deren herstellung und arzneimittel, die sie enthalten.
FR2649701B2 (fr) * 1988-12-15 1991-11-22 Rhone Poulenc Sante Derives d'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant

Also Published As

Publication number Publication date
DE69103271T2 (de) 1994-12-22
JPH05507918A (ja) 1993-11-11
FR2663029A1 (fr) 1991-12-13
WO1991018892A1 (fr) 1991-12-12
ATE109475T1 (de) 1994-08-15
EP0532602A1 (de) 1993-03-24
DK0532602T3 (da) 1994-09-12
US5340824A (en) 1994-08-23
EP0532602B1 (de) 1994-08-03
FR2663029B1 (fr) 1992-07-31
CA2080005A1 (fr) 1991-12-08
ES2057901T3 (es) 1994-10-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee