DE69615696D1 - Heterocyclische verbindungen zur behandlung von myokard-ischemia - Google Patents

Heterocyclische verbindungen zur behandlung von myokard-ischemia

Info

Publication number
DE69615696D1
DE69615696D1 DE69615696T DE69615696T DE69615696D1 DE 69615696 D1 DE69615696 D1 DE 69615696D1 DE 69615696 T DE69615696 T DE 69615696T DE 69615696 T DE69615696 T DE 69615696T DE 69615696 D1 DE69615696 D1 DE 69615696D1
Authority
DE
Germany
Prior art keywords
pct
optionally branched
compounds
myocard
ischemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69615696T
Other languages
English (en)
Other versions
DE69615696T2 (de
Inventor
Jean-Pierre Rieu
Jean-Francois Patoiseau
W John
Bruno Legrand
Jean-Pierre Valentin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of DE69615696D1 publication Critical patent/DE69615696D1/de
Application granted granted Critical
Publication of DE69615696T2 publication Critical patent/DE69615696T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69615696T 1995-07-26 1996-07-25 Heterocyclische verbindungen zur behandlung von myokard-ischemia Expired - Fee Related DE69615696T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9509079A FR2737207B1 (fr) 1995-07-26 1995-07-26 Nouvelles n-heterocyclyl-1-aryloxyalcoyl-4-piperidinamines substituees, leur preparation et leur application en therapeutique
PCT/FR1996/001176 WO1997005134A1 (fr) 1995-07-26 1996-07-25 Composes heterocycliques pour le traitement de l'ischemie myocardique

Publications (2)

Publication Number Publication Date
DE69615696D1 true DE69615696D1 (de) 2001-11-08
DE69615696T2 DE69615696T2 (de) 2002-07-11

Family

ID=9481394

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69615696T Expired - Fee Related DE69615696T2 (de) 1995-07-26 1996-07-25 Heterocyclische verbindungen zur behandlung von myokard-ischemia

Country Status (17)

Country Link
US (1) US6011032A (de)
EP (1) EP0842174B1 (de)
JP (1) JPH11509857A (de)
KR (1) KR19990035986A (de)
CN (1) CN1103338C (de)
AT (1) ATE206423T1 (de)
AU (1) AU707950B2 (de)
BR (1) BR9609911A (de)
CA (1) CA2228691A1 (de)
DE (1) DE69615696T2 (de)
DK (1) DK0842174T3 (de)
ES (1) ES2165514T3 (de)
FR (1) FR2737207B1 (de)
MX (1) MX9800705A (de)
NZ (1) NZ315347A (de)
PT (1) PT842174E (de)
WO (1) WO1997005134A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2788775B1 (fr) * 1999-01-22 2001-04-13 Pf Medicament Nouvelles n-alcoyl-n-[1-(omega-(arylalcoyloxy)alcoyl] piperidin-4-yl]-4h-3,1-benzo(thia/oxa)zines-2-amines substituees, leur preparation et leur application en therapeutique
FR2788771B1 (fr) * 1999-01-22 2001-04-13 Pf Medicament Nouvelles 1,2-alcoyl-1-[1-[aryl (alcoyl) oxyalcoyl] piperidin-4-yl]-3-aryl isothiourees substituees, leur preparation et leur application en therapeutique
AU4314700A (en) * 1999-04-28 2000-11-17 Banyu Pharmaceutical Co., Ltd. Processes for the preparation of piperidylmethylpyridine derivatives
FR3001151B1 (fr) 2013-01-21 2016-04-08 Pf Medicament Association d'un bloqueur de courant sodique lent et d'un inhibiteur du courant if sinusal et les compositions pharmarceutiques la contenant
CN114349745B (zh) * 2022-01-14 2023-12-08 黑龙江中医药大学 一种用于治疗心肌缺血的药物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives

Also Published As

Publication number Publication date
AU6703196A (en) 1997-02-26
ES2165514T3 (es) 2002-03-16
JPH11509857A (ja) 1999-08-31
DE69615696T2 (de) 2002-07-11
PT842174E (pt) 2002-03-28
NZ315347A (en) 2000-01-28
BR9609911A (pt) 1999-03-02
WO1997005134A1 (fr) 1997-02-13
CN1193972A (zh) 1998-09-23
CA2228691A1 (fr) 1997-02-13
EP0842174A1 (de) 1998-05-20
FR2737207A1 (fr) 1997-01-31
DK0842174T3 (da) 2002-01-28
KR19990035986A (ko) 1999-05-25
CN1103338C (zh) 2003-03-19
AU707950B2 (en) 1999-07-22
EP0842174B1 (de) 2001-10-04
MX9800705A (es) 1998-10-31
ATE206423T1 (de) 2001-10-15
FR2737207B1 (fr) 1997-10-17
US6011032A (en) 2000-01-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee