DE69230177T2 - Verfahren und gerät zur automatischen bestimmung von gewebe - Google Patents
Verfahren und gerät zur automatischen bestimmung von gewebeInfo
- Publication number
- DE69230177T2 DE69230177T2 DE69230177T DE69230177T DE69230177T2 DE 69230177 T2 DE69230177 T2 DE 69230177T2 DE 69230177 T DE69230177 T DE 69230177T DE 69230177 T DE69230177 T DE 69230177T DE 69230177 T2 DE69230177 T2 DE 69230177T2
- Authority
- DE
- Germany
- Prior art keywords
- processor
- sequence
- steps
- time
- procedures
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 10
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/0092—Scheduling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
- B25J—MANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
- B25J9/00—Programme-controlled manipulators
- B25J9/16—Programme controls
- B25J9/1656—Programme controls characterised by programming, planning systems for manipulators
- B25J9/1671—Programme controls characterised by programming, planning systems for manipulators characterised by simulation, either to verify existing program or to create and verify new program, CAD/CAM oriented, graphic oriented programming systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
- B25J—MANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
- B25J9/00—Programme-controlled manipulators
- B25J9/16—Programme controls
- B25J9/1679—Programme controls characterised by the tasks executed
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/0092—Scheduling
- G01N2035/0093—Scheduling random access not determined by physical position
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B2219/00—Program-control systems
- G05B2219/30—Nc systems
- G05B2219/45—Nc applications
- G05B2219/45092—Analysing or chemical synthesis robot, moving samples from station to station
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B2219/00—Program-control systems
- G05B2219/30—Nc systems
- G05B2219/45—Nc applications
- G05B2219/45118—Endoscopic, laparoscopic manipulator
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Robotics (AREA)
- Immunology (AREA)
- Mechanical Engineering (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/740,285 US5355439A (en) | 1991-08-05 | 1991-08-05 | Method and apparatus for automated tissue assay |
PCT/US1992/006478 WO1993003451A1 (en) | 1991-08-05 | 1992-08-04 | Method and apparatus for automated tissue assay |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69230177D1 DE69230177D1 (de) | 1999-11-25 |
DE69230177T2 true DE69230177T2 (de) | 2000-02-03 |
Family
ID=24975849
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69230177T Expired - Lifetime DE69230177T2 (de) | 1991-08-05 | 1992-08-04 | Verfahren und gerät zur automatischen bestimmung von gewebe |
Country Status (6)
Country | Link |
---|---|
US (2) | US5355439A (de) |
EP (1) | EP0600939B1 (de) |
JP (1) | JP3439762B2 (de) |
AT (1) | ATE185912T1 (de) |
DE (1) | DE69230177T2 (de) |
WO (1) | WO1993003451A1 (de) |
Families Citing this family (93)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5696887A (en) * | 1991-08-05 | 1997-12-09 | Biotek Solutions, Incorporated | Automated tissue assay using standardized chemicals and packages |
JPH08500434A (ja) * | 1992-05-13 | 1996-01-16 | オーストラリアン バイオメディカル コーポレーション リミテッド | スライド標本用自動染色装置 |
JPH06273423A (ja) * | 1993-03-18 | 1994-09-30 | Daikin Ind Ltd | 測定装置の測定時間短縮方法 |
US5439649A (en) * | 1993-09-29 | 1995-08-08 | Biogenex Laboratories | Automated staining apparatus |
US6451551B1 (en) * | 1994-03-11 | 2002-09-17 | Biogenex Laboratories | Releasing embedding media from tissue specimens |
US5930461A (en) * | 1994-03-24 | 1999-07-27 | Bernstein; Steven A. | Method and apparatus for automated tissue assay |
DE19516638A1 (de) * | 1995-05-05 | 1996-11-07 | Bayerische Motoren Werke Ag | Ventiltrieb mit einer gesonderten Steuereinrichtung für insbesondere variable Ventilöffnungswinkel, vor allem für Brennkraftmaschinen |
US5737498A (en) * | 1995-07-11 | 1998-04-07 | Beckman Instruments, Inc. | Process automation method and apparatus |
JP3504394B2 (ja) * | 1995-09-08 | 2004-03-08 | 松下電器産業株式会社 | 部品配列のデータ作成方法 |
JP2001505648A (ja) * | 1996-07-05 | 2001-04-24 | ベックマン コールター インコーポレイテッド | 自動試料処理システム |
US7141213B1 (en) * | 1996-07-05 | 2006-11-28 | Beckman Coulter, Inc. | Automated sample processing system |
US6735531B2 (en) | 1996-10-07 | 2004-05-11 | Lab Vision Corporation | Method and apparatus for automatic tissue staining |
US5839091A (en) * | 1996-10-07 | 1998-11-17 | Lab Vision Corporation | Method and apparatus for automatic tissue staining |
US5985214A (en) | 1997-05-16 | 1999-11-16 | Aurora Biosciences Corporation | Systems and methods for rapidly identifying useful chemicals in liquid samples |
US6699710B1 (en) * | 1998-02-25 | 2004-03-02 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor tissue microarrays for rapid molecular profiling |
US6103518A (en) * | 1999-03-05 | 2000-08-15 | Beecher Instruments | Instrument for constructing tissue arrays |
US8298485B2 (en) * | 1999-07-08 | 2012-10-30 | Lee H. Angros | In situ heat induced antigen recovery and staining apparatus and method |
US7897106B2 (en) * | 1999-07-08 | 2011-03-01 | Lee Angros | Situ heat induced antigen recovery and staining apparatus and method |
EP1208378B9 (de) * | 1999-07-08 | 2014-12-10 | Lee H. Angros | Vorrichtung und verfahren zum nachweis und zum anfärben von antigenen |
US7951612B2 (en) * | 1999-07-08 | 2011-05-31 | Lee H. Angros | In situ heat induced antigen recovery and staining apparatus and method |
SE9903112L (sv) | 1999-09-03 | 2001-03-04 | Delaval Holding Ab | Grafiskt användargränssnitt och förfarande relaterat därtill |
AU782452B2 (en) * | 1999-12-13 | 2005-07-28 | Government of The United States of America, as represented by The Secretary Department of Health & Human Services, The National Institutes of Health, The | High-throughput tissue microarray technology and applications |
KR100743727B1 (ko) * | 1999-12-14 | 2007-07-30 | 유니버시티 오브 마이애미 | 신속한 조직 프로세서 |
DE10041231A1 (de) * | 2000-08-22 | 2002-03-07 | Leica Microsystems | Vorrichtung zur Behandlung von Objekten |
DE10052834B4 (de) * | 2000-10-24 | 2019-09-19 | Leica Biosystems Nussloch Gmbh | Verfahren zur Behandlung von Objekten |
DE10052832A1 (de) * | 2000-10-24 | 2002-04-25 | Leica Microsystems | Vorrichtung zur Behandlung von Objekten |
US20040085443A1 (en) * | 2000-12-13 | 2004-05-06 | Kallioniemi Olli P | Method and system for processing regions of interest for objects comprising biological material |
US20030215936A1 (en) * | 2000-12-13 | 2003-11-20 | Olli Kallioniemi | High-throughput tissue microarray technology and applications |
US6383801B1 (en) * | 2001-03-19 | 2002-05-07 | Beecher Instruments | Double z-drive tissue array instrument |
JP2005503560A (ja) * | 2001-09-17 | 2005-02-03 | ユロス・アクチボラゲット | ミクロ流体機器用のメソッド・ハンドラ |
WO2003042788A2 (en) * | 2001-11-13 | 2003-05-22 | Chromavision Medical Systems, Inc. | A system for tracking biological samples |
JP2003149255A (ja) * | 2001-11-15 | 2003-05-21 | Toyobo Co Ltd | 直交座標および円筒座標に移動可能な分注装置 |
US20040033163A1 (en) * | 2001-11-26 | 2004-02-19 | Lab Vision Corporation | Automated tissue staining system and reagent container |
US6998270B2 (en) | 2001-11-26 | 2006-02-14 | Lab Vision Corporation | Automated tissue staining system and reagent container |
US20040197897A1 (en) * | 2002-03-19 | 2004-10-07 | Leighton Stephen B. | Tissue array instrument |
US7303725B2 (en) | 2002-04-15 | 2007-12-04 | Ventana Medical Systems, Inc. | Automated high volume slide staining system |
US7468161B2 (en) | 2002-04-15 | 2008-12-23 | Ventana Medical Systems, Inc. | Automated high volume slide processing system |
US11249095B2 (en) | 2002-04-15 | 2022-02-15 | Ventana Medical Systems, Inc. | Automated high volume slide processing system |
AU2003901871A0 (en) * | 2003-03-31 | 2003-05-08 | Vision Biosystems Limited | A method and apparatus for fluid dispensation, preparation and dilation |
CA2489412A1 (en) * | 2002-07-16 | 2004-01-22 | Ventana Medical Systems, Inc. | Tray for automated histochemical processing |
WO2005084263A2 (en) | 2004-03-02 | 2005-09-15 | Dakocytomation Denmark A/S | Reagent delivery system, dispensing device and container for a biological staining apparatus |
US7648678B2 (en) | 2002-12-20 | 2010-01-19 | Dako Denmark A/S | Method and system for pretreatment of tissue slides |
US7875245B2 (en) * | 2003-05-14 | 2011-01-25 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
US7850912B2 (en) * | 2003-05-14 | 2010-12-14 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
US7584019B2 (en) * | 2003-12-15 | 2009-09-01 | Dako Denmark A/S | Systems and methods for the automated pre-treatment and processing of biological samples |
AU2003900810A0 (en) * | 2003-02-24 | 2003-03-13 | Vision Biosystems Limited | Method of scheduling |
WO2004104557A2 (en) * | 2003-05-19 | 2004-12-02 | Ventana Medical Systems, Inc. | Electrophoretic in situ tissue staining |
US7642064B2 (en) | 2003-06-24 | 2010-01-05 | Ventana Medical Systems, Inc. | Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest |
ATE437369T1 (de) * | 2003-06-24 | 2009-08-15 | Ventana Med Syst Inc | Enzymkatalysierte metalldeposition zum verstärkten in-situ-nachweis von immunhistologischen epitopen und nukleinsäuresequenzen |
US9518899B2 (en) | 2003-08-11 | 2016-12-13 | Sakura Finetek U.S.A., Inc. | Automated reagent dispensing system and method of operation |
US7767152B2 (en) | 2003-08-11 | 2010-08-03 | Sakura Finetek U.S.A., Inc. | Reagent container and slide reaction retaining tray, and method of operation |
US7744817B2 (en) | 2003-08-11 | 2010-06-29 | Sakura Finetek U.S.A., Inc. | Manifold assembly |
US7501283B2 (en) | 2003-08-11 | 2009-03-10 | Sakura Finetek U.S.A., Inc. | Fluid dispensing apparatus |
US8026106B1 (en) | 2003-12-18 | 2011-09-27 | Ventana Medical Systems, Inc. | Removal of mercuric chloride crystals from fixed tissues |
JP4871737B2 (ja) * | 2003-12-23 | 2012-02-08 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | 平坦な表面の効率的な薄膜液体処理のための方法および装置 |
US7168694B2 (en) * | 2004-01-22 | 2007-01-30 | Sakura Finetek U.S.A., Inc. | Multi-axis workpiece chuck |
WO2006004739A2 (en) | 2004-06-29 | 2006-01-12 | Dako Denmark A/S | Method of pre-treatment and staining of and support device for a biological sample |
ES2505253T3 (es) * | 2004-07-23 | 2014-10-09 | Ventana Medical Systems, Inc. | Método y aparato para aplicar fluidos a una muestra biológica |
US7867443B2 (en) * | 2004-07-23 | 2011-01-11 | Dako Denmark A/S | Method and apparatus for automated pre-treatment and processing of biological samples |
US7854899B2 (en) * | 2004-08-26 | 2010-12-21 | The United States Of America As Represented By The Secretary Of Health And Human Services | Template methods and devices for preparing sample arrays |
EP1824647A1 (de) * | 2004-10-20 | 2007-08-29 | Abb Research Ltd. | System und verfahren zur programmierung eines industrieroboters |
GB0501590D0 (en) * | 2005-01-25 | 2005-03-02 | Ceres Power Ltd | Processing of enhanced performance LSCF fuel cell cathode microstructure and a fuel cell cathode |
US7618809B2 (en) | 2005-03-23 | 2009-11-17 | Gebing Ronald A | Microarrayer with coaxial multiple punches |
MX2007014655A (es) | 2005-05-24 | 2008-04-02 | Lee H Angros | Aparato y metodo para la recuperacion y coloracion de antigenos in situ inducida por calor. |
ATE526437T1 (de) * | 2005-06-28 | 2011-10-15 | Univ Oklahoma | Verfahren zur züchtung und entnahme von kohlenstoffnanoröhren |
WO2008051310A2 (en) * | 2006-05-09 | 2008-05-02 | Advanced Liquid Logic, Inc. | Droplet manipulation systems |
US8459509B2 (en) | 2006-05-25 | 2013-06-11 | Sakura Finetek U.S.A., Inc. | Fluid dispensing apparatus |
ATE529732T1 (de) * | 2006-10-30 | 2011-11-15 | Ventana Med Syst Inc | Dünnfilmvorrichtung und -verfahren |
DE102007008713B4 (de) * | 2007-02-20 | 2019-07-11 | Leica Biosystems Nussloch Gmbh | Gewebeinfiltrationsvorrichtung |
US8703492B2 (en) | 2007-04-06 | 2014-04-22 | Qiagen Gaithersburg, Inc. | Open platform hybrid manual-automated sample processing system |
US7985375B2 (en) | 2007-04-06 | 2011-07-26 | Qiagen Gaithersburg, Inc. | Sample preparation system and method for processing clinical specimens |
JP2009036723A (ja) * | 2007-08-03 | 2009-02-19 | Olympus Corp | 自動分析装置および動作環境設定方法 |
JP5170737B2 (ja) * | 2007-09-20 | 2013-03-27 | シスメックス株式会社 | 検体分析装置 |
US8346574B2 (en) | 2008-02-29 | 2013-01-01 | Dako Denmark A/S | Systems and methods for tracking and providing workflow information |
US20090253163A1 (en) * | 2008-04-02 | 2009-10-08 | General Electric Company | Iterative staining of biological samples |
WO2010025425A1 (en) | 2008-08-29 | 2010-03-04 | Angros Lee H | Multiplexed microscope slide staining apparatus |
WO2010056883A1 (en) | 2008-11-12 | 2010-05-20 | Ventana Medical Systems, Inc. | Methods and apparatuses for heating slides carrying specimens |
US9953141B2 (en) | 2009-11-18 | 2018-04-24 | Becton, Dickinson And Company | Laboratory central control unit method and system |
WO2011085225A1 (en) * | 2010-01-08 | 2011-07-14 | Wake Forest University Health Sciences | Delivery system |
US8752732B2 (en) | 2011-02-01 | 2014-06-17 | Sakura Finetek U.S.A., Inc. | Fluid dispensing system |
EP2683328B1 (de) | 2011-03-07 | 2017-11-08 | Wake Forest University Health Sciences | Freisetzungssystem |
US8932543B2 (en) | 2011-09-21 | 2015-01-13 | Sakura Finetek U.S.A., Inc. | Automated staining system and reaction chamber |
US8580568B2 (en) | 2011-09-21 | 2013-11-12 | Sakura Finetek U.S.A., Inc. | Traceability for automated staining system |
EP2780688B1 (de) * | 2011-11-16 | 2022-09-14 | Leica Biosystems Melbourne Pty Ltd | Vorrichtung zur bearbeitung biologischer proben |
US9817221B2 (en) * | 2012-06-29 | 2017-11-14 | General Electric Company | Systems and methods for processing and imaging of biological samples |
CN102818904A (zh) * | 2012-07-02 | 2012-12-12 | 浙江大学 | 全自动组织切片制作分析一体机 |
EP2860529A1 (de) * | 2013-10-08 | 2015-04-15 | Roche Diagniostics GmbH | Flüssigkeitsausgabekartusche mit einer flexiblen Blase |
CN117054211A (zh) | 2013-12-13 | 2023-11-14 | 文塔纳医疗系统公司 | 生物样本的自动化组织学处理及相关的技术 |
CN106716104B (zh) * | 2014-09-22 | 2020-12-22 | 株式会社日冷生物科学 | 自动组织染色装置和自动组织染色方法 |
JP6419547B2 (ja) * | 2014-11-21 | 2018-11-07 | 国立研究開発法人産業技術総合研究所 | 動作指令生成装置、動作指令生成方法、コンピュータプログラム、及び処理システム。 |
JP6602873B2 (ja) * | 2015-09-11 | 2019-11-06 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
US20210109121A1 (en) * | 2019-10-11 | 2021-04-15 | Sakura Finetek Europe B.V. | Automatic transfer between tissue processing modules |
CN110836804A (zh) * | 2019-11-20 | 2020-02-25 | 湖北工程学院 | 组织染色机智能计时的方法及装置 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3665148A (en) * | 1971-04-07 | 1972-05-23 | Gen Motors Corp | Six-axis manipulator |
SU603577A1 (ru) * | 1976-07-06 | 1978-04-25 | Ордена Ленина, Ордена Октябрьской Революции И Ордена Трудового Красного Знамени Завод "Ростсельмаш" | Промышленный робот |
JPS5514157A (en) * | 1978-07-14 | 1980-01-31 | Shin Meiwa Ind Co Ltd | Automatic welder |
IT1144709B (it) * | 1981-05-15 | 1986-10-29 | Dea Spa | Sistema di misura dimensionale servito da una pluralita di bracci operativi e controllato da un sistema a calcolatore |
GB2143205B (en) * | 1983-07-15 | 1986-07-16 | Leicester Polytechnic | Robots |
JPS6149205A (ja) * | 1984-08-16 | 1986-03-11 | Seiko Instr & Electronics Ltd | ロボツト制御方式 |
US4727494A (en) * | 1985-01-01 | 1988-02-23 | Zymark Corporation | Computerized robot control system with scheduling feature |
GB8605324D0 (en) * | 1986-03-04 | 1986-04-09 | Rank Taylor Hobson Ltd | Metrological apparatus |
US4843566A (en) * | 1986-03-07 | 1989-06-27 | Hewlett-Packard Company | Robot motion control system |
JPS63502931A (ja) * | 1986-03-26 | 1988-10-27 | ベックマン インスツルメンツ インコーポレーテッド | 自動化された多目的分析化学処理総合施設および研究所作業装置 |
US4835711A (en) * | 1986-05-30 | 1989-05-30 | Zymark Corporation | Quickly reconfigurable robotic system |
JPS645779A (en) * | 1987-06-29 | 1989-01-10 | Fanuc Ltd | Robot arrangement examination system |
US4979093A (en) * | 1987-07-16 | 1990-12-18 | Cavro Scientific Instruments | XYZ positioner |
US5016170A (en) * | 1988-09-22 | 1991-05-14 | Pollalis Spiro N | Task management |
DE387409T1 (de) * | 1989-03-15 | 1991-02-07 | Hewlett-Packard Co., Palo Alto, Calif., Us | Folgeregeln zum voreinspritzen von durch chromatographie zu analysierenden proben. |
US5355304A (en) * | 1990-01-30 | 1994-10-11 | Demoranville Victoria E | Clinical laboratory work-flow system which semi-automates validated immunoassay and electrophoresis protocols |
-
1991
- 1991-08-05 US US07/740,285 patent/US5355439A/en not_active Expired - Lifetime
-
1992
- 1992-08-04 AT AT92916866T patent/ATE185912T1/de not_active IP Right Cessation
- 1992-08-04 DE DE69230177T patent/DE69230177T2/de not_active Expired - Lifetime
- 1992-08-04 JP JP50380693A patent/JP3439762B2/ja not_active Expired - Lifetime
- 1992-08-04 EP EP92916866A patent/EP0600939B1/de not_active Expired - Lifetime
- 1992-08-04 WO PCT/US1992/006478 patent/WO1993003451A1/en active IP Right Grant
-
1994
- 1994-03-24 US US08/218,143 patent/US5675715A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5355439A (en) | 1994-10-11 |
US5675715A (en) | 1997-10-07 |
JPH08506888A (ja) | 1996-07-23 |
EP0600939B1 (de) | 1999-10-20 |
JP3439762B2 (ja) | 2003-08-25 |
WO1993003451A1 (en) | 1993-02-18 |
EP0600939A4 (en) | 1996-05-15 |
DE69230177D1 (de) | 1999-11-25 |
ATE185912T1 (de) | 1999-11-15 |
EP0600939A1 (de) | 1994-06-15 |
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