MX2007014655A - Aparato y metodo para la recuperacion y coloracion de antigenos in situ inducida por calor. - Google Patents

Aparato y metodo para la recuperacion y coloracion de antigenos in situ inducida por calor.

Info

Publication number
MX2007014655A
MX2007014655A MX2007014655A MX2007014655A MX2007014655A MX 2007014655 A MX2007014655 A MX 2007014655A MX 2007014655 A MX2007014655 A MX 2007014655A MX 2007014655 A MX2007014655 A MX 2007014655A MX 2007014655 A MX2007014655 A MX 2007014655A
Authority
MX
Mexico
Prior art keywords
slide
individually
reaction compartment
reagent
microscope
Prior art date
Application number
MX2007014655A
Other languages
English (en)
Inventor
Lee H Angros
Thomas L Byers
Original Assignee
Lee H Angros
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lee H Angros filed Critical Lee H Angros
Publication of MX2007014655A publication Critical patent/MX2007014655A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/44—Sample treatment involving radiation, e.g. heat
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0059—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
    • A61F2007/0063—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit for cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/0085—Devices for generating hot or cold treatment fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/14—Means for pressure control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00138—Slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0412—Block or rack elements with a single row of samples
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Thermal Sciences (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

En la presente se contempla un aparato automatico y metodo de coloracion y recuperacion de antigenos para portaobjetos de microscopio que incorporan una pluralidad de compartimientos de reaccion presurizables miniaturizados que pueden operar individualmente para procesar individual e independientemente una pluralidad de portaobjetos de microscopio individuales. El aparato incorpora de preferencia elementos de soporte de portaobjetos que se pueden mover independientemente y que tienen cada uno una placa de calentamiento que puede calentarse individualmente. Cada elemento de soporte de portaobjetos soporta de preferencia un solo portaobjetos de microscopio. Cada portaobjetos de microscopio puede ser encerrado dentro de un compartimiento de reaccion presurizable individual. Presiones que excedan una atmosfera o menos de una atmosfera pueden crearse y mantenerse en el compartimiento de reaccion antes de, durante o despues de que empiece el calentamiento del portaobjetos. Gracias a la capacidad de presurizar y regular la presion dentro del compartimiento de reaccion, y de calentar individualmente cada portaobjetos, cada portaobjetos y una solucion liquida o reactivo sobre el mismo puede ser calentado hasta temperaturas que no podrian ser obtenidas sin el ambiente presurizado encerrado del compartimiento de reaccion. Tambien se puede usar una tira de suministro de reactivo que tenga una pluralidad de modulos de reactivo reconfigurables.
MX2007014655A 2005-05-24 2006-05-24 Aparato y metodo para la recuperacion y coloracion de antigenos in situ inducida por calor. MX2007014655A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68404705P 2005-05-24 2005-05-24
US68938605P 2005-06-10 2005-06-10
US73074405P 2005-10-27 2005-10-27
PCT/US2006/020156 WO2006127852A2 (en) 2005-05-24 2006-05-24 In situ heat induced antigen recovery and staining apparatus and method

Publications (1)

Publication Number Publication Date
MX2007014655A true MX2007014655A (es) 2008-04-02

Family

ID=37452811

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007014655A MX2007014655A (es) 2005-05-24 2006-05-24 Aparato y metodo para la recuperacion y coloracion de antigenos in situ inducida por calor.

Country Status (10)

Country Link
US (6) US8361388B2 (es)
EP (1) EP1888739B1 (es)
JP (1) JP5335420B2 (es)
CN (1) CN101228429B (es)
AU (1) AU2006249956A1 (es)
BR (1) BRPI0609898A2 (es)
CA (1) CA2609453C (es)
HK (1) HK1120110A1 (es)
MX (1) MX2007014655A (es)
WO (1) WO2006127852A2 (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006249956A1 (en) 2005-05-24 2006-11-30 Angros, Lee H In situ heat induced antigen recovery and staining apparatus and method
CA3042430C (en) * 2007-10-02 2022-10-11 Theranos Ip Company, Llc Modular point-of-care devices and uses thereof
US20090139311A1 (en) * 2007-10-05 2009-06-04 Applied Biosystems Inc. Biological Analysis Systems, Devices, and Methods
GB2477648B (en) 2008-08-29 2013-02-20 Lee H Angros In situ heat induced antigen recovery and staining apparatus and method
FR2938062B1 (fr) * 2008-11-05 2014-02-28 Biomerieux Sa Dispositif de preparation et/ou de traitement d'un echantillon biologique
US8067241B2 (en) * 2009-08-26 2011-11-29 General Electric Company Method and apparatus for antigen retrieval process
ES2699950T3 (es) 2010-10-06 2019-02-13 Biocare Medical Llc Procedimiento y sistema para el procesamiento eficaz de muestras biológicas
EP2468862A1 (en) * 2010-12-23 2012-06-27 Qiagen GmbH Method and kit for processing wax-embedded biological samples
US9945763B1 (en) 2011-02-18 2018-04-17 Biocare Medical, Llc Methods and systems for immunohistochemistry heat retrieval of biological samples
US8932543B2 (en) 2011-09-21 2015-01-13 Sakura Finetek U.S.A., Inc. Automated staining system and reaction chamber
CN104053774B (zh) * 2011-11-17 2016-09-07 瑞尼克斯有限公司 微流体装置、方法和应用
WO2014001531A2 (en) * 2012-06-29 2014-01-03 Victorious Medical Systems Aps A system and a dip tank for washing and target retrieval of tissue samples mounted on microscope slides
JP6346191B2 (ja) * 2012-11-01 2018-06-20 ライカ・バイオシステムズ・メルボルン・プロプライエタリー・リミテッドＬｅｉｃａ Ｂｉｏｓｙｓｔｅｍｓ Ｍｅｌｂｏｕｒｎｅ Ｐｔｙ Ｌｔｄ 流体輸送システム
EP3080579B1 (en) * 2013-12-13 2022-07-27 Ventana Medical Systems, Inc. Automated slide processing apparatus
CA2928922C (en) 2013-12-13 2019-03-12 Ventana Medical Systems, Inc. Automated processing systems and methods of thermally processing microscope slides
AU2014363678B2 (en) 2013-12-13 2016-12-08 Ventana Medical Systems, Inc. Staining reagents and other liquids for histological processing of biological specimens and associated technology
US10634590B2 (en) 2014-03-11 2020-04-28 Emd Millipore Corporation IHC, tissue slide fluid exchange disposable and system
CN104744588A (zh) * 2015-04-03 2015-07-01 福州大学 一种用于制备抗体的抗原预处理方法
WO2016190111A1 (ja) * 2015-05-26 2016-12-01 オリンパス株式会社 検体染色装置および検体染色方法
WO2017014313A1 (ja) * 2015-07-23 2017-01-26 昭栄化学工業株式会社 金属酸化物ナノ結晶の製造方法、多元素酸化物ナノ結晶の製造方法および金属酸化物ナノ結晶
CN105987839B (zh) * 2016-06-03 2018-09-28 浙江世纪康大医疗科技股份有限公司 一种edta-柠檬酸抗原修复液
CN105987840B (zh) * 2016-06-03 2018-09-28 浙江世纪康大医疗科技股份有限公司 一种柠檬酸抗原修复液
WO2017218882A1 (en) 2016-06-16 2017-12-21 Nanocytomics, LLC Automated staining system
CN106124288A (zh) * 2016-06-18 2016-11-16 张阳康 一种熔样装置
US20190316993A1 (en) * 2016-12-20 2019-10-17 Diapath S.P.A. Disposable container for stains or reagents for staining machines of biological material and staining system comprising said container
CN106769985B (zh) * 2016-12-30 2021-03-02 湖南微灵仪器有限公司 固体表面吸附红外检测可视化系统
WO2020016113A1 (en) * 2018-07-16 2020-01-23 Ventana Medical Systems, Inc. Microscope slide processing systems, consumable stainer modules, and methods of using the same
CN109556929A (zh) * 2018-10-18 2019-04-02 广州安必平医药科技股份有限公司 反应仓、抗原修复仪及其使用方法
CN109540802B (zh) * 2018-12-13 2021-06-04 东北大学 一种生物体液中葡萄糖浓度的光声检测装置及方法
US11992845B2 (en) 2018-12-14 2024-05-28 Leica Biosystems Melbourne Pty Ltd Reagent cassette
US11724261B1 (en) 2019-05-13 2023-08-15 Integrated Dna Technologies, Inc. Synthesizer system with inflatable seal and valve arrangement
WO2020229578A1 (en) * 2019-05-14 2020-11-19 Ventana Medical Systems, Inc. System including a biological sample treatment chamber
CN110411810A (zh) * 2019-09-04 2019-11-05 深圳褀氏生物医疗电子有限公司 一种免疫组化染色机及免疫组化染色方法
CN211235173U (zh) * 2019-11-26 2020-08-11 莱卡生物系统努斯洛赫有限责任公司 一种组织处理设备
US20230055997A1 (en) * 2019-12-31 2023-02-23 Sakura Finetek U.S.A., Inc. Automated staining system and reaction chamber
CN114305860B (zh) * 2022-03-10 2022-05-17 广州三森健康产业科技有限公司 一种多功能带有热循环的蒸汽眼罩
CN115323805B (zh) * 2022-08-31 2024-04-05 湖州倍亨纺织有限公司 一种提升聚乳酸染色牢度的热熔染色方法

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3645690A (en) 1968-01-22 1972-02-29 Beckman Instruments Inc Automated chemical analyzer
US3574064A (en) * 1968-05-09 1971-04-06 Aerojet General Co Automated biological reaction instrument
JPS5335420B2 (es) 1971-12-25 1978-09-27
US3853092A (en) 1973-10-25 1974-12-10 Corning Glass Works Apparatus for nutating and staining a microscope slide
US4296070A (en) 1980-06-16 1981-10-20 Eastman Kodak Company Slide distributor for a chemical analyzer
US4510119A (en) 1982-05-07 1985-04-09 Centocor, Inc. Diagnostic test bead transfer apparatus
JPH076992B2 (ja) 1985-06-21 1995-01-30 富士写真フイルム株式会社 化学分析装置
EP0231951B1 (en) 1986-02-07 1993-06-09 Fuji Photo Film Co., Ltd. Chemical analysis apparatus
US5154889A (en) 1986-08-07 1992-10-13 Fuji Photo Film Co., Ltd. Chemical analysis apparatus
US4847208A (en) 1987-07-29 1989-07-11 Bogen Steven A Apparatus for immunohistochemical staining and method of rinsing a plurality of slides
US5089233A (en) 1989-06-12 1992-02-18 Eastman Kodak Company Processing apparatus for a chemical reaction pack
US5209903A (en) 1989-09-06 1993-05-11 Toa Medical Electronics, Co., Ltd. Synthetic apparatus for inspection of blood
US5346672A (en) * 1989-11-17 1994-09-13 Gene Tec Corporation Devices for containing biological specimens for thermal processing
US5250262A (en) 1989-11-22 1993-10-05 Vettest S.A. Chemical analyzer
US6472217B1 (en) 1990-03-02 2002-10-29 Ventana Medical Systems, Inc. Slide aqueous volume controlling apparatus
US5595707A (en) 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
US5225325A (en) 1990-03-02 1993-07-06 Ventana Medical Systems, Inc. Immunohistochemical staining method and reagents therefor
US5425918A (en) 1990-07-18 1995-06-20 Australian Biomedical Corporation Apparatus for automatic tissue staining for immunohistochemistry
US5244787A (en) 1991-01-31 1993-09-14 Biogenex Laboratories Antigen retrieval in formalin-fixed tissues using microwave energy
US5273905A (en) 1991-02-22 1993-12-28 Amoco Corporation Processing of slide mounted material
DE4117833C2 (de) 1991-05-29 1993-10-07 Medite Ges Fuer Medizintechnik Verfahren und Vorrichtung zur Färbung von auf Objektträgern angeordneten histologischen Präparaten
US5355439A (en) 1991-08-05 1994-10-11 Bio Tek Instruments Method and apparatus for automated tissue assay
US5696887A (en) 1991-08-05 1997-12-09 Biotek Solutions, Incorporated Automated tissue assay using standardized chemicals and packages
US5232664A (en) 1991-09-18 1993-08-03 Ventana Medical Systems, Inc. Liquid dispenser
FI915731A0 (fi) 1991-12-05 1991-12-05 Derek Henry Potter Foerfarande och anordning foer reglering av temperaturen i ett flertal prov.
US5578452A (en) 1992-01-16 1996-11-26 Biogenex Laboratories Enhancement of immunochemical staining in aldehyde-fixed tissues
US5316452A (en) 1992-05-11 1994-05-31 Gilbert Corporation Dispensing assembly with interchangeable cartridge pumps
US6180061B1 (en) 1992-05-11 2001-01-30 Cytologix Corporation Moving platform slide stainer with heating elements
US5645114A (en) 1992-05-11 1997-07-08 Cytologix Corporation Dispensing assembly with interchangeable cartridge pumps
US5947167A (en) 1992-05-11 1999-09-07 Cytologix Corporation Dispensing assembly with interchangeable cartridge pumps
US5439649A (en) * 1993-09-29 1995-08-08 Biogenex Laboratories Automated staining apparatus
US6451551B1 (en) 1994-03-11 2002-09-17 Biogenex Laboratories Releasing embedding media from tissue specimens
US6632598B1 (en) 1994-03-11 2003-10-14 Biogenex Laboratories Deparaffinization compositions and methods for their use
US5525514A (en) 1994-04-06 1996-06-11 Johnson & Johnson Clinical Diagnostics, Inc. Wash detection method for dried chemistry test elements
AUPN038995A0 (en) 1995-01-05 1995-01-27 Australian Biomedical Corporation Limited Method and apparatus for human or animal cell sample treatment
EP0843169B1 (de) * 1995-02-25 2003-03-19 Roche Diagnostics GmbH Vorrichtung zur Bearbeitung von Proben auf Objekträgern
US5551487A (en) 1995-03-10 1996-09-03 Hewlett-Packard Company Micro-dispenser for preparing assay plates
US5645200A (en) * 1995-07-14 1997-07-08 Mcdowell Bros. Garment hanger
US6127188A (en) * 1995-10-06 2000-10-03 Mj Research, Inc. Method and apparatus for controlling evaporation in histological procedures
AUPN923596A0 (en) 1996-04-12 1996-05-09 Australian Biomedical Corporation Limited Method and apparatus for treatment of human or animal cell samples
US5939251A (en) * 1996-07-12 1999-08-17 Hu; Min Apparatus and method for simplifying the processes in creating a sealed space on slides to conduct molecular biological reactions therein
US5839091A (en) 1996-10-07 1998-11-17 Lab Vision Corporation Method and apparatus for automatic tissue staining
US5804141A (en) 1996-10-15 1998-09-08 Chianese; David Reagent strip slide treating apparatus
US5958341A (en) 1996-12-23 1999-09-28 American Registry Of Pathology Apparatus for efficient processing of tissue samples on slides
US5734999A (en) * 1997-01-24 1998-04-07 John J. Nicholas Safety device for swimming pools
US5948359A (en) 1997-03-21 1999-09-07 Biogenex Laboratories Automated staining apparatus
US6489171B1 (en) 1997-04-18 2002-12-03 Cell Marque Corporation Chemical dispensing system and method
US5985214A (en) 1997-05-16 1999-11-16 Aurora Biosciences Corporation Systems and methods for rapidly identifying useful chemicals in liquid samples
US5922604A (en) 1997-06-05 1999-07-13 Gene Tec Corporation Thin reaction chambers for containing and handling liquid microvolumes
US5882601A (en) 1997-06-18 1999-03-16 Merck & Co., Ltd. Deflected septum seal access port
US6093574A (en) 1997-08-11 2000-07-25 Ventana Medical Systems Method and apparatus for rinsing a microscope slide
DE69839963D1 (de) 1997-08-20 2008-10-16 Univ Miami Hochqualitatives durchlaufendes verfahren zur fixierung, dehydratisierung, entfettung und imprägnation von geweben
US6649368B1 (en) 1997-10-24 2003-11-18 Cell Marque Corporation Composition and method for treating tissue samples
ATE347098T1 (de) 1997-12-23 2006-12-15 Dako Denmark As Kasette zur bearbeitung einer auf der oberfläche eines trägers angebrachten probe
US6269846B1 (en) 1998-01-13 2001-08-07 Genetic Microsystems, Inc. Depositing fluid specimens on substrates, resulting ordered arrays, techniques for deposition of arrays
US6428752B1 (en) 1998-05-14 2002-08-06 Affymetrix, Inc. Cleaning deposit devices that form microarrays and the like
US20030211630A1 (en) 1998-02-27 2003-11-13 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
CA2320750C (en) * 1998-02-27 2004-08-24 Ventana Medical Systems, Inc. System and method of aspirating and dispensing reagent
US6096271A (en) 1998-02-27 2000-08-01 Cytologix Corporation Random access slide stainer with liquid waste segregation
US6183693B1 (en) * 1998-02-27 2001-02-06 Cytologix Corporation Random access slide stainer with independent slide heating regulation
US6855559B1 (en) 1998-09-03 2005-02-15 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6582962B1 (en) 1998-02-27 2003-06-24 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
US6660228B1 (en) * 1998-03-02 2003-12-09 Cepheid Apparatus for performing heat-exchanging, chemical reactions
US6495106B1 (en) 1998-03-24 2002-12-17 Biogenex Laboratories Automated staining apparatus
ID23331A (id) 1998-03-31 2000-04-05 American Cyanamid Co Komposisi insektisida semprot yang memiliki kemanjuran kuat
AU766614B2 (en) 1998-09-03 2003-10-23 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
ATE381016T1 (de) 1998-10-28 2007-12-15 Covaris Inc Vorrichtung und verfahren zur kontrolle einer akustischen behandlung
US6948843B2 (en) 1998-10-28 2005-09-27 Covaris, Inc. Method and apparatus for acoustically controlling liquid solutions in microfluidic devices
US6544798B1 (en) 1999-02-26 2003-04-08 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6245297B1 (en) 1999-04-16 2001-06-12 Pe Corporation (Ny) Apparatus and method for transferring small volumes of substances
US6673620B1 (en) 1999-04-20 2004-01-06 Cytologix Corporation Fluid exchange in a chamber on a microscope slide
US6773676B2 (en) 1999-04-27 2004-08-10 Agilent Technologies, Inc. Devices for performing array hybridization assays and methods of using the same
JP2001004506A (ja) * 1999-06-24 2001-01-12 Shichiro Miyazawa 電子顕微鏡試料作製装置及び電子顕微鏡試料作製方法
US7897106B2 (en) 1999-07-08 2011-03-01 Lee Angros Situ heat induced antigen recovery and staining apparatus and method
US7951612B2 (en) 1999-07-08 2011-05-31 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
EP1208378B9 (en) 1999-07-08 2014-12-10 Lee H. Angros Antigen recovery and/or staining apparatus and method
US8298485B2 (en) 1999-07-08 2012-10-30 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
AU5967900A (en) 1999-07-21 2001-02-13 Dako A/S A method of controlling the temperature of a specimen in or on a solid support member
US6403036B1 (en) 1999-09-29 2002-06-11 Ventana Medical Systems, Inc. Temperature monitoring system for an automated biological reaction apparatus
US6358473B1 (en) 1999-10-05 2002-03-19 Albert Coello Microscope slide heater
US6403931B1 (en) 1999-10-07 2002-06-11 Ventana Medical Systems, Inc. Slide heater calibrator and temperature converter apparatus and method
US6403037B1 (en) * 2000-02-04 2002-06-11 Cepheid Reaction vessel and temperature control system
US6783934B1 (en) * 2000-05-01 2004-08-31 Cepheid, Inc. Methods for quantitative analysis of nucleic acid amplification reaction
US6943035B1 (en) 2000-05-19 2005-09-13 Genetix Limited Liquid dispensing apparatus and method
US6627159B1 (en) 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
US7025933B2 (en) 2000-07-06 2006-04-11 Robodesign International, Inc. Microarray dispensing with real-time verification and inspection
EP1260265B1 (de) 2001-05-25 2005-02-02 Tecan Trading AG System mit Verfahrenseinheit zum Hybridisieren von Nukleinsäureproben, Proteinen und Gewebeschnitten
JP3797418B2 (ja) * 2001-05-29 2006-07-19 茂樹 並松 抗原賦活化法及びその抗原賦活剤
JP2003057156A (ja) * 2001-08-17 2003-02-26 Aloka Co Ltd サンプル処理装置
US7270785B1 (en) 2001-11-02 2007-09-18 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having fixed slide platforms
US7378058B2 (en) 2002-01-30 2008-05-27 Ventana Medical Systems, Inc. Method and apparatus for modifying pressure within a fluid dispenser
WO2003089140A1 (en) 2002-04-15 2003-10-30 Ventana Medical Systems, Inc. Automated high volume slide staining system
US7378055B2 (en) 2002-04-26 2008-05-27 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having fixed slide platforms
US20040029184A1 (en) 2002-08-09 2004-02-12 Pickcell Laboratories B.V. Method for antigen retrieval and submersion fluid compositions for use therein
US6935567B2 (en) * 2002-12-09 2005-08-30 Sanyo Electric Co., Ltd. Incubator
US7850912B2 (en) 2003-05-14 2010-12-14 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
US7584019B2 (en) 2003-12-15 2009-09-01 Dako Denmark A/S Systems and methods for the automated pre-treatment and processing of biological samples
US7875245B2 (en) 2003-05-14 2011-01-25 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
US7648678B2 (en) 2002-12-20 2010-01-19 Dako Denmark A/S Method and system for pretreatment of tissue slides
US7354705B2 (en) * 2003-01-30 2008-04-08 Schering Corporation Methods for cancer prognosis and diagnosis
USD495425S1 (en) 2003-03-24 2004-08-31 Vision Biosystems, Limited Cover tile
US20050079517A1 (en) * 2003-06-19 2005-04-14 Michael Goncharko Controlled evaporation, temperature control and packaging for optical inspection of biological samples
US7273591B2 (en) * 2003-08-12 2007-09-25 Idexx Laboratories, Inc. Slide cartridge and reagent test slides for use with a chemical analyzer, and chemical analyzer for same
DE202004001263U1 (de) 2004-01-28 2004-11-18 E-BENK TECH CO., LTD., Junghe Stativ
US7615370B2 (en) 2004-07-08 2009-11-10 Tecan Trading Ag System having device for preventing air bubbles in a hybridization chamber and corresponding method
DE202004012163U1 (de) * 2004-07-08 2004-10-07 Tecan Trading Ag System mit Einrichtung zum Verhindern von Luftblasen in einer Hybridisierkammer
US7867443B2 (en) 2004-07-23 2011-01-11 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
AU2012247048B2 (en) 2005-05-24 2014-11-27 Angros, Lee H In situ heat induced antigen recovery and staining apparatus and method
RU2439572C2 (ru) 2005-05-24 2012-01-10 Ли Х. АНГРОС АППАРАТ ДЛЯ ВЫЗВАННОГО ТЕПЛОВОЙ ОБРАБОТКОЙ ВОССТАНОВЛЕНИЯ АНТИГЕНА in situ И ОКРАШИВАНИЯ И СПОСОБ
AU2006249956A1 (en) 2005-05-24 2006-11-30 Angros, Lee H In situ heat induced antigen recovery and staining apparatus and method
US7875242B2 (en) 2006-10-17 2011-01-25 Preyas Sarabhai Shah Slide stainer with multiple heater stations
US20090093028A1 (en) * 2007-10-05 2009-04-09 Joy Doran Peterson Apparatus and methods for treating biomass

Also Published As

Publication number Publication date
US10697868B2 (en) 2020-06-30
EP1888739B1 (en) 2021-08-11
CN101228429A (zh) 2008-07-23
HK1120110A1 (en) 2009-03-20
CA2609453C (en) 2014-07-08
US9354145B2 (en) 2016-05-31
WO2006127852A2 (en) 2006-11-30
AU2006249956A1 (en) 2006-11-30
US20160274007A1 (en) 2016-09-22
US20110150725A1 (en) 2011-06-23
US20110229978A1 (en) 2011-09-22
CN101228429B (zh) 2013-04-10
WO2006127852A3 (en) 2007-03-29
US20170328820A1 (en) 2017-11-16
US20140024134A1 (en) 2014-01-23
EP1888739A2 (en) 2008-02-20
CA2609453A1 (en) 2006-11-30
EP1888739A4 (en) 2012-07-18
US11585737B2 (en) 2023-02-21
WO2006127852A8 (en) 2009-10-08
US9719895B2 (en) 2017-08-01
BRPI0609898A2 (pt) 2011-10-11
JP5335420B2 (ja) 2013-11-06
US20200326266A1 (en) 2020-10-15
US8361388B2 (en) 2013-01-29
US8541244B2 (en) 2013-09-24
JP2009506300A (ja) 2009-02-12

Similar Documents

Publication Publication Date Title
MX2007014655A (es) Aparato y metodo para la recuperacion y coloracion de antigenos in situ inducida por calor.
GB2477648B (en) In situ heat induced antigen recovery and staining apparatus and method
KR102103237B1 (ko) 멀티웰 플레이트용 온도제어요소와 생물학적 시료의 냉동 및/또는 해동을 위한 방법 및 장치
JP2009506300A5 (es)
US20060275861A1 (en) In situ heat induced antigen recovery and staining apparatus and method
WO2008030914A3 (en) Device for carrying out chemical or biological reactions
JPH0319700A (ja) 温度調節装置および反応器
ATE442576T1 (de) Vereinfachte gewebeverarbeitung
CN102939371B (zh) 细胞破裂
EP1955771A3 (de) Temperierblock mit Temperiereinrichtungen
DE502007006675D1 (de) Vorrichtung zum Brühen eines flüssigen Lebens- oder Genussmittels
DK2053378T3 (da) Reagensbeholder og objektglasreaktion og holdebakke og anvendelsesfremgangsmåde
JP2007516447A5 (es)
NO20083550L (no) Fremgangsmate for a indusere kjernedannelse i et materiale
ATE173173T1 (de) Vorrichtung zum aufbereiten und/oder extrahieren von proben mittels eines verdampfungsfähigen mittels bei erhöhter temperatur
DE602006016959D1 (de) Verfahren und vorrichtung zur herstellung eines formteils aus kunststoff
WO2004033099A3 (en) Methods and systems for multiplexing ir-mediated heating on a microchip
JP6424885B2 (ja) 増幅装置、増幅方法及び増幅システム
ATE168039T1 (de) Vorrichtung zum auslösen und/oder fördern chemischer oder physikalischer prozesse in einem material, insbesondere probenmaterial
ATE471191T1 (de) Vorrichtung und verfahren zur thermischen trocknung von filterkuchen in membrankammerfilterpressen
ATE445460T1 (de) Thermocyclervorrichtung
ES2615644T3 (es) Aparato de extracción de ácido nucleico a velocidad ultra-alta y procedimiento de extracción de ácido nucleico usando el mismo
ATE138535T1 (de) Vorrichtung für einen regenerativ- wärmeaustauscher
PT2084266E (pt) Sistema de cultura celular, processo para a sua produção e uso em testes pré-clínicos
RU2439572C2 (ru) АППАРАТ ДЛЯ ВЫЗВАННОГО ТЕПЛОВОЙ ОБРАБОТКОЙ ВОССТАНОВЛЕНИЯ АНТИГЕНА in situ И ОКРАШИВАНИЯ И СПОСОБ

Legal Events

Date Code Title Description
FG Grant or registration