DE69219900D1 - 5-o-desosaminylerythronolid derivate - Google Patents

5-o-desosaminylerythronolid derivate

Info

Publication number
DE69219900D1
DE69219900D1 DE69219900T DE69219900T DE69219900D1 DE 69219900 D1 DE69219900 D1 DE 69219900D1 DE 69219900 T DE69219900 T DE 69219900T DE 69219900 T DE69219900 T DE 69219900T DE 69219900 D1 DE69219900 D1 DE 69219900D1
Authority
DE
Germany
Prior art keywords
moiety
optionally substituted
desosaminylerythronolide
hydrogen
derivate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69219900T
Other languages
English (en)
Other versions
DE69219900T2 (de
Inventor
Toshifumi Taisho Pharmac Asaka
Yoko Taisho Pharmaceuti Misawa
Masato Taisho Pharma Kashimura
Shigeo Taisho Pharmac Morimoto
Katsuo Taisho Pharmac Hatayama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69219900D1 publication Critical patent/DE69219900D1/de
Publication of DE69219900T2 publication Critical patent/DE69219900T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69219900T 1991-12-27 1992-12-25 5-o-desosaminylerythronolid derivate Expired - Fee Related DE69219900T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP34682691 1991-12-27
JP19936892 1992-07-27
JP27986792 1992-10-19
PCT/JP1992/001714 WO1993013116A1 (en) 1991-12-27 1992-12-25 5-o-desosaminylerythronolide derivative

Publications (2)

Publication Number Publication Date
DE69219900D1 true DE69219900D1 (de) 1997-06-26
DE69219900T2 DE69219900T2 (de) 1997-09-11

Family

ID=27327638

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69217989T Expired - Fee Related DE69217989T2 (de) 1991-12-27 1992-12-25 5-0-Desosaminylerrythronolide-Derivate
DE69219900T Expired - Fee Related DE69219900T2 (de) 1991-12-27 1992-12-25 5-o-desosaminylerythronolid derivate

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69217989T Expired - Fee Related DE69217989T2 (de) 1991-12-27 1992-12-25 5-0-Desosaminylerrythronolide-Derivate

Country Status (10)

Country Link
US (2) US5523399A (de)
EP (2) EP0619320B1 (de)
JP (2) JP3099366B2 (de)
KR (2) KR100266183B1 (de)
AT (2) ATE149508T1 (de)
AU (2) AU667334B2 (de)
CA (2) CA2126664A1 (de)
DE (2) DE69217989T2 (de)
ES (2) ES2104118T3 (de)
WO (2) WO1993013115A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021199A1 (en) * 1992-04-22 1993-10-28 Taisho Pharmaceutical Co., Ltd. 5-o-desosaminylerythronolide a derivative
CA2154550A1 (en) * 1993-01-26 1994-08-04 Yoko Misawa 5-o-desosaminylerythronolide derivatives
CN1159757A (zh) * 1994-08-12 1997-09-17 大正制药株式会社 抑制白细胞介素5产生的抑制剂
FR2738571B1 (fr) * 1995-09-11 1997-10-17 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
FR2739620B1 (fr) * 1995-10-09 1997-12-19 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
USRE38426E1 (en) 1995-10-09 2004-02-10 Aventis Pharma S.A. 5-O-deosaminyl 6-O-methyl erythronolide A derivatives, preparation method therefor and use thereof for preparing biologically active materials
PT874863E (pt) * 1995-11-08 2003-06-30 Abbott Lab Derivados 3-desoxi-3-descladinose de eritromicinasa e b
US6274715B1 (en) * 1995-11-08 2001-08-14 Abbott Laboratories Tricyclic erythromycin derivatives
US5747466A (en) * 1995-11-08 1998-05-05 Abbott Laboratories 3-deoxy-3-descladinose derivatives of erythromycins A and B
JP2000500133A (ja) * 1995-11-08 2000-01-11 アボツト・ラボラトリーズ 三環式エリスロマイシン誘導体
ATE296832T1 (de) * 1996-09-04 2005-06-15 Abbott Lab 6-o-substituierte ketoliden mit antibakteriellen wirkung
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
US5804565A (en) * 1996-09-24 1998-09-08 Taisho Pharmaceutical Co., Ltd. Erythromycin A derivatives
BR9713302A (pt) 1996-11-27 2000-03-21 Taisho Pharmaceutical Co Ltd Derivado de eritromicina a, composição farmacêutica, preparação antibacteriana, processo para o tratamento de uma doença bacteriologicamente infecciosa, e, uso do derivado de eritromicina a ou um seu sal farcamaceuticamente aceitável.
WO1998042720A1 (fr) * 1997-03-24 1998-10-01 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
JP2004514643A (ja) * 1997-10-29 2004-05-20 大正製薬株式会社 エリスロマイシンａ誘導体
WO1999021868A1 (fr) 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
WO1999021867A1 (fr) * 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
AU1504899A (en) * 1997-12-11 1999-06-28 Hokuriku Seiyaku Co. Ltd Erythromycin derivatives
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
FR2777282B1 (fr) * 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
ES2272273T3 (es) * 1999-04-16 2007-05-01 Kosan Biosciences, Inc. Agentes antiinfecciosos macrolidos.
WO2000071557A1 (en) * 1999-05-24 2000-11-30 Pfizer Products Inc. 13-methyl-erythromycin derivatives
US6420535B1 (en) * 1999-06-07 2002-07-16 Abbott Laboratories 6-O-carbamate ketolide derivatives
US6946446B2 (en) 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
EP1146051A3 (de) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A-Derivate
US20020115621A1 (en) * 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
WO2005012322A1 (ja) * 2003-08-05 2005-02-10 Taisho Pharmaceutical Co., Ltd. エリスロマイシンａ １１，１２−サイクリックカーボネートの製造方法
US7276487B2 (en) 2003-09-23 2007-10-02 Enanta Pharmaceuticals, Inc. 9a, 11-3C-bicyclic 9a-azalide derivatives
US20080207536A1 (en) * 2004-07-28 2008-08-28 Ranbaxy Laboratories Limited Antibacterial Agents
US7402568B2 (en) 2004-09-29 2008-07-22 Enanta Pharmaceuticals, Inc. Bicyclic 9a-azalide derivatives
EP1836211B1 (de) * 2004-12-21 2010-03-03 Pfizer Products Inc. Makrolide
US7271155B2 (en) 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives
ES2317527T3 (es) * 2005-01-13 2009-04-16 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Decladinosil-macrolidos que presentan actividad anti-inflamatoria.
US8293715B2 (en) * 2007-08-06 2012-10-23 Taisho Pharmaceutical Co., Ltd. 10a-Azalide compound crosslinked at 10a- and 12-positions
WO2009023196A1 (en) * 2007-08-10 2009-02-19 Y's Therapeutics Co, Ltd. Modulation of immune responses by administration of roxithromycin or its derivative
WO2009139181A1 (ja) 2008-05-15 2009-11-19 大正製薬株式会社 ４員環構造を有する１０ａ－アザライド化合物
US8143369B2 (en) * 2009-06-02 2012-03-27 International Business Machines Corporation Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof
CN101863941A (zh) * 2010-06-03 2010-10-20 武汉大学 3-氧-取代的6,11-二-氧-甲基红霉素a的衍生物
CN104961785B (zh) * 2015-06-19 2019-01-11 北京理工大学 一种新型酰内酯衍生物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923784A (en) * 1973-09-10 1975-12-02 Hoffmann La Roche Erythromycin a derivatives
US4518590A (en) * 1984-04-13 1985-05-21 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
GB8521402D0 (en) * 1985-08-28 1985-10-02 Beecham Group Plc Chemical compounds
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
DK90788A (da) * 1987-02-24 1988-08-25 Beecham Group Plc Erythromycinderivater
JPH0196190A (ja) * 1987-10-07 1989-04-14 Toyo Jozo Co Ltd ６−０−アルキル−エリスロマイシンａ　サイクリック１１，１２−カーボネート
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
WO1993013115A1 (en) 1993-07-08
KR940703842A (ko) 1994-12-12
EP0619319B1 (de) 1997-03-05
DE69217989D1 (de) 1997-04-10
KR100265916B1 (ko) 2000-09-15
EP0619320A1 (de) 1994-10-12
ES2104118T3 (es) 1997-10-01
DE69219900T2 (de) 1997-09-11
AU3172893A (en) 1993-07-28
EP0619319A4 (de) 1994-11-02
AU663145B2 (en) 1995-09-28
KR100266183B1 (ko) 2000-09-15
ES2101290T3 (es) 1997-07-01
JP3132002B2 (ja) 2001-02-05
ATE149508T1 (de) 1997-03-15
KR940703841A (ko) 1994-12-12
US5631354A (en) 1997-05-20
EP0619320B1 (de) 1997-05-21
DE69217989T2 (de) 1997-06-12
AU667334B2 (en) 1996-03-21
AU3172793A (en) 1993-07-28
EP0619320A4 (de) 1994-11-02
WO1993013116A1 (en) 1993-07-08
CA2126664A1 (en) 1993-07-08
EP0619319A1 (de) 1994-10-12
JP3099366B2 (ja) 2000-10-16
US5523399A (en) 1996-06-04
CA2126665A1 (en) 1993-07-08
ATE153341T1 (de) 1997-06-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee