DE3888066D1 - Saccharid-Derivate. - Google Patents

Saccharid-Derivate.

Info

Publication number
DE3888066D1
DE3888066D1 DE88810646T DE3888066T DE3888066D1 DE 3888066 D1 DE3888066 D1 DE 3888066D1 DE 88810646 T DE88810646 T DE 88810646T DE 3888066 T DE3888066 T DE 3888066T DE 3888066 D1 DE3888066 D1 DE 3888066D1
Authority
DE
Germany
Prior art keywords
saccharide derivatives
immunostimulant
antiinflammatory
saccharides
deprotection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE88810646T
Other languages
English (en)
Other versions
DE3888066T2 (de
Inventor
Ingolf Macher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Sandoz AG
Sandoz Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG, Sandoz Patent GmbH filed Critical Sandoz AG
Priority to DE3888066T priority Critical patent/DE3888066T2/de
Application granted granted Critical
Publication of DE3888066D1 publication Critical patent/DE3888066D1/de
Publication of DE3888066T2 publication Critical patent/DE3888066T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Ceramic Products (AREA)
  • Glass Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE3888066T 1987-09-23 1988-09-21 Saccharid-Derivate. Expired - Lifetime DE3888066T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE3888066T DE3888066T2 (de) 1987-09-23 1988-09-21 Saccharid-Derivate.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873731953 DE3731953A1 (de) 1987-09-23 1987-09-23 Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung
DE3888066T DE3888066T2 (de) 1987-09-23 1988-09-21 Saccharid-Derivate.

Publications (2)

Publication Number Publication Date
DE3888066D1 true DE3888066D1 (de) 1994-04-07
DE3888066T2 DE3888066T2 (de) 1994-08-04

Family

ID=6336635

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19873731953 Withdrawn DE3731953A1 (de) 1985-10-22 1987-09-23 Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung
DE3888066T Expired - Lifetime DE3888066T2 (de) 1987-09-23 1988-09-21 Saccharid-Derivate.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19873731953 Withdrawn DE3731953A1 (de) 1985-10-22 1987-09-23 Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung

Country Status (18)

Country Link
EP (1) EP0309411B1 (de)
JP (1) JP2744912B2 (de)
KR (1) KR970005346B1 (de)
AT (1) ATE102213T1 (de)
AU (1) AU614772B2 (de)
CA (1) CA1335892C (de)
DE (2) DE3731953A1 (de)
DK (1) DK170170B1 (de)
ES (1) ES2061724T3 (de)
FI (1) FI89494C (de)
HU (1) HU201559B (de)
IE (1) IE63517B1 (de)
IL (1) IL87799A0 (de)
MY (1) MY103552A (de)
NZ (1) NZ226274A (de)
PL (1) PL157779B1 (de)
PT (1) PT88568B (de)
ZA (1) ZA887161B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE139699T1 (de) * 1988-08-19 1996-07-15 Univ Australian Auf phosphozucker basierende antientzündliche und/oder immunitätsunterdrückende arzneimittel
AU627500B2 (en) * 1988-08-19 1992-08-27 Australian National University, The Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs
US5597573A (en) * 1989-05-04 1997-01-28 Igen, Inc. Lipid-A analogs: new monosaccharide and disaccharide intermediates for eliciting therapeutic antibodies and for antitumor and antiviral activities
DD295854A5 (de) * 1989-12-11 1991-11-14 ��@���������@�������k�� Lipid-a-austauschstoffe mit immunoaktivierender und antitumorwirkung
US5593969A (en) * 1991-09-03 1997-01-14 Igen Incorporated Lipid-A analogs: monosaccharide and dissaccharide compounds for inhibiting binding of lipid A receptors to lipid A receptors
EP1178051B1 (de) * 2000-02-10 2008-05-28 Mitsui Chemicals, Inc. Verfahren zur selektiven herstellung eines 1-phosphoryliertem zuckerderivativ-anomers und verfahren zur herstellung von nukleosiden
CA2317305A1 (en) * 2000-08-29 2002-02-28 Tassos P. Anastassiades Method of enhancing chondrocyte cell growth and glycosaminoglycan production
FR2862062B1 (fr) * 2003-11-06 2005-12-23 Oreal Lipide a et composition topique, notamment cosmetique, le comprenant
EP3707147A1 (de) * 2017-11-07 2020-09-16 Università Degli Studi Di Milano - Bicocca Neue synthetische agonisten des tlr4-rezeptors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0143840B1 (de) * 1983-05-06 1990-08-29 Wisconsin Alumni Research Foundation Monosaccharide verbindungen mit immunostimulierender wirkung
ATE54920T1 (de) 1984-04-21 1990-08-15 Sandoz Ag 2,3-diamino-2,3-didesoxyhexose-derivate, verfahren zu ihrer herstellung und ihre verwendung.
EP0219514A4 (de) 1985-04-03 1988-04-26 Wisconsin Alumni Res Found Verfahren zum vorbeugen von krankheiten, verursacht durch gram-negatives endotoxin bei säugetieren.
NL8601551A (nl) 1985-06-28 1987-01-16 Sandoz Ag Nieuwe saccharides, hun bereiding en farmaceutische samenstellingen, die hen bevatten.
US4746742A (en) * 1985-11-28 1988-05-24 Toho Yakuhin Kogyo Kabushiki Kaisha Analogs of nonreducing monosaccharide moiety of lipid A

Also Published As

Publication number Publication date
KR890005138A (ko) 1989-05-13
DK170170B1 (da) 1995-06-06
HU201559B (en) 1990-11-28
DK525588D0 (da) 1988-09-21
EP0309411A3 (de) 1991-07-24
EP0309411A2 (de) 1989-03-29
PT88568B (pt) 1992-11-30
FI884345A (fi) 1989-03-24
KR970005346B1 (ko) 1997-04-15
DK525588A (da) 1989-03-24
ES2061724T3 (es) 1994-12-16
ZA887161B (en) 1990-05-30
AU2278588A (en) 1989-04-20
IE882859L (en) 1989-03-23
FI89494C (fi) 1993-10-11
DE3888066T2 (de) 1994-08-04
NZ226274A (en) 1991-03-26
DE3731953A1 (de) 1989-04-06
FI89494B (fi) 1993-06-30
AU614772B2 (en) 1991-09-12
HUT50193A (en) 1989-12-28
JPH01121295A (ja) 1989-05-12
MY103552A (en) 1993-07-31
ATE102213T1 (de) 1994-03-15
IE63517B1 (en) 1995-05-03
JP2744912B2 (ja) 1998-04-28
PT88568A (pt) 1988-10-01
PL274862A1 (en) 1989-06-12
IL87799A0 (en) 1989-03-31
FI884345A0 (fi) 1988-09-21
CA1335892C (en) 1995-06-13
EP0309411B1 (de) 1994-03-02
PL157779B1 (pl) 1992-07-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS AG, BASEL, CH

8328 Change in the person/name/address of the agent

Free format text: SPOTT WEINMILLER & PARTNER, 80336 MUENCHEN