DE3566263D1 - Novel cyanoimidazole nucleoside derivatives - Google Patents
Novel cyanoimidazole nucleoside derivativesInfo
- Publication number
- DE3566263D1 DE3566263D1 DE8585301656T DE3566263T DE3566263D1 DE 3566263 D1 DE3566263 D1 DE 3566263D1 DE 8585301656 T DE8585301656 T DE 8585301656T DE 3566263 T DE3566263 T DE 3566263T DE 3566263 D1 DE3566263 D1 DE 3566263D1
- Authority
- DE
- Germany
- Prior art keywords
- cyanoimidazole
- novel
- nucleoside derivatives
- nucleoside
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 CYANOIMIDAZOLE NUCLEOSIDE DERIVATIVES Chemical class 0.000 title abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 239000002777 nucleoside Substances 0.000 abstract 2
- 229940053202 antiepileptics carboxamide derivative Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59049563A JPS60193997A (ja) | 1984-03-14 | 1984-03-14 | 新規シアノイミダゾ−ルリボヌクレオシド誘導体およびその製造法 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3566263D1 true DE3566263D1 (de) | 1988-12-22 |
Family
ID=12834668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585301656T Expired DE3566263D1 (de) | 1984-03-14 | 1985-03-11 | Novel cyanoimidazole nucleoside derivatives |
Country Status (7)
Country | Link |
---|---|
US (1) | US4728729A (de) |
EP (1) | EP0155164B1 (de) |
JP (1) | JPS60193997A (de) |
KR (1) | KR850006429A (de) |
AT (1) | ATE38677T1 (de) |
DE (1) | DE3566263D1 (de) |
ES (1) | ES8606378A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60193997A (ja) * | 1984-03-14 | 1985-10-02 | Sumitomo Chem Co Ltd | 新規シアノイミダゾ−ルリボヌクレオシド誘導体およびその製造法 |
EP0389723A1 (de) * | 1989-03-29 | 1990-10-03 | Merrell Dow Pharmaceuticals Inc. | Alpha-glukosidase-Inhibitoren |
JPH0649650B2 (ja) * | 1990-05-17 | 1994-06-29 | 旭化成工業株式会社 | 4―カルバモイル―1―β―D―リボフラノシル―イミダゾリウム―5―オレイトを有効成分とする用途 |
JPH0559085A (ja) * | 1990-12-27 | 1993-03-09 | Nippon Kayaku Co Ltd | イミダゾール塩基を有するオキセタノシン誘導体 |
BR9712527A (pt) * | 1996-10-16 | 2000-03-08 | Icn Pharmaceuticals | L-nucleosìdeos monocìclicos, análogos e seus empregos |
EP1132393B1 (de) * | 1996-10-16 | 2003-04-09 | ICN Pharmaceuticals, Inc. | L-Ribavirin und dessen Verwendung |
GB201701087D0 (en) * | 2017-01-23 | 2017-03-08 | Univ Leuven Kath | Novel prodrugs of mizoribine |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US29835A (en) * | 1860-08-28 | Surveyor s instrument | ||
DE2012888C3 (de) * | 1970-03-14 | 1981-04-02 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von 5-Azapyrimidinnucleosiden |
USRE29835E (en) | 1971-06-01 | 1978-11-14 | Icn Pharmaceuticals | 1,2,4-Triazole nucleosides |
US3968103A (en) * | 1972-09-28 | 1976-07-06 | Icn Pharmaceuticals, Inc. | 1,2,3-Triazole nucleosides |
US3888843A (en) * | 1973-06-12 | 1975-06-10 | Toyo Jozo Kk | 4-carbamoyl-1-' -d-ribofuranosylimidazolium-5-olate |
AU502122B2 (en) * | 1976-07-02 | 1979-07-12 | Sumitomo Chemical Company, Limited | 5-0-acylated-imidazole-4-carboxamide derivatives |
JPS604802B2 (ja) * | 1976-09-07 | 1985-02-06 | 住友化学工業株式会社 | 制癌剤 |
US4140788A (en) * | 1976-11-10 | 1979-02-20 | Sumitomo Chemical Company, Limited | N-Substituted imidazolecarboxamide derivatives |
AU507066B1 (en) * | 1977-09-06 | 1980-01-31 | Sumitomo Chemical Company, Limited | 2-Substituted-5-Hydroxy-1h-Imidazole 4-Carbozamide Derivatives |
JPS5461194A (en) * | 1977-10-21 | 1979-05-17 | Takeda Chem Ind Ltd | Preparation of n22substituted 2*66diaminonebularin |
JPS5495568A (en) * | 1978-01-06 | 1979-07-28 | Sumitomo Chem Co Ltd | Novel imidazoleacetic acid derivative |
JPS54100371A (en) * | 1978-01-25 | 1979-08-08 | Sumitomo Chem Co Ltd | Novel imidazole c-nucleoside derivative |
JPS55130998A (en) * | 1979-04-02 | 1980-10-11 | Takeda Chem Ind Ltd | N2-substituted 2,6-diaminonebularin |
CA1151651A (en) * | 1979-08-08 | 1983-08-09 | Takao Kiyohara | Antitumor and immunosuppressive 4-carbamoyl imidazolium-5-olate derivatives, pharmaceutical composition and production thereof |
JPS5645460A (en) * | 1979-09-20 | 1981-04-25 | Sumitomo Chem Co Ltd | Novel imidazolyl sulfonate derivative |
JPS5671075A (en) * | 1979-11-12 | 1981-06-13 | Sumitomo Chem Co Ltd | Novel imidazole derivative |
US4464531A (en) * | 1981-04-20 | 1984-08-07 | Sumitomo Chemical Company, Limited | 4-Carbamoylimidazolium-5-olate derivatives |
US4410696A (en) * | 1981-09-24 | 1983-10-18 | Sumitomo Chemical Company, Limited | Antitumor and immunosuppressive 4-carbamoylimidazolium-5-olate derivatives |
JPS59167515A (ja) * | 1983-03-15 | 1984-09-21 | Ajinomoto Co Inc | 免疫機能増強剤 |
JPS60193997A (ja) * | 1984-03-14 | 1985-10-02 | Sumitomo Chem Co Ltd | 新規シアノイミダゾ−ルリボヌクレオシド誘導体およびその製造法 |
-
1984
- 1984-03-14 JP JP59049563A patent/JPS60193997A/ja active Pending
-
1985
- 1985-03-05 KR KR1019850001367A patent/KR850006429A/ko not_active IP Right Cessation
- 1985-03-08 US US06/709,647 patent/US4728729A/en not_active Expired - Fee Related
- 1985-03-11 EP EP85301656A patent/EP0155164B1/de not_active Expired
- 1985-03-11 DE DE8585301656T patent/DE3566263D1/de not_active Expired
- 1985-03-11 AT AT85301656T patent/ATE38677T1/de not_active IP Right Cessation
- 1985-03-13 ES ES541215A patent/ES8606378A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0155164A2 (de) | 1985-09-18 |
ES541215A0 (es) | 1986-04-16 |
US4728729A (en) | 1988-03-01 |
ES8606378A1 (es) | 1986-04-16 |
EP0155164B1 (de) | 1988-11-17 |
KR850006429A (ko) | 1985-10-05 |
EP0155164A3 (en) | 1986-04-09 |
ATE38677T1 (de) | 1988-12-15 |
JPS60193997A (ja) | 1985-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |