FI814148L - Nya trisubstituerade pyrimido/5,4-d/pyrimidiner deras framstaellning och deras anvaendning saosom laekemedel - Google Patents

Nya trisubstituerade pyrimido/5,4-d/pyrimidiner deras framstaellning och deras anvaendning saosom laekemedel

Info

Publication number
FI814148L
FI814148L FI814148A FI814148A FI814148L FI 814148 L FI814148 L FI 814148L FI 814148 A FI814148 A FI 814148A FI 814148 A FI814148 A FI 814148A FI 814148 L FI814148 L FI 814148L
Authority
FI
Finland
Prior art keywords
deras
trisubstituerade
ceekemedel
pyrimidiner
nya
Prior art date
Application number
FI814148A
Other languages
English (en)
Other versions
FI71151C (fi
FI71151B (fi
Inventor
Josef Roch
Erich Mueller
Berthold Narr
Josef Nickl
Walter Haarmann
Johannes Maximili Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of FI814148L publication Critical patent/FI814148L/fi
Application granted granted Critical
Publication of FI71151B publication Critical patent/FI71151B/fi
Publication of FI71151C publication Critical patent/FI71151C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
FI814148A 1980-12-27 1981-12-23 Foerfarande foer framstaellning av farmakologiskt vaerdefulla trisubstituerade pyrimido/5,4-d/pyrimidiner FI71151C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3049207 1980-12-27
DE19803049207 DE3049207A1 (de) 1980-12-27 1980-12-27 Neue trisubstituierte pyrimido (5,4-d) pyrimidine, ihre herstellung und ihre verwendung als arzneimittel

Publications (3)

Publication Number Publication Date
FI814148L true FI814148L (fi) 1982-06-28
FI71151B FI71151B (fi) 1986-08-14
FI71151C FI71151C (fi) 1986-11-24

Family

ID=6120399

Family Applications (1)

Application Number Title Priority Date Filing Date
FI814148A FI71151C (fi) 1980-12-27 1981-12-23 Foerfarande foer framstaellning av farmakologiskt vaerdefulla trisubstituerade pyrimido/5,4-d/pyrimidiner

Country Status (19)

Country Link
US (1) US4478833A (fi)
EP (1) EP0055444B1 (fi)
JP (1) JPS57134485A (fi)
AT (1) ATE12232T1 (fi)
AU (1) AU547792B2 (fi)
CA (1) CA1176247A (fi)
DE (2) DE3049207A1 (fi)
DK (1) DK548981A (fi)
ES (1) ES508343A0 (fi)
FI (1) FI71151C (fi)
GB (1) GB2090833B (fi)
GR (1) GR76356B (fi)
IE (1) IE52323B1 (fi)
IL (1) IL64647A (fi)
NO (1) NO158256C (fi)
NZ (1) NZ199376A (fi)
PH (1) PH22243A (fi)
PT (1) PT74199B (fi)
ZA (1) ZA818934B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3423092A1 (de) * 1984-06-22 1986-01-02 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 8-alkylthio-2-piperazino-pyrimido(5,4-d) pyrimidine, ihre herstellung und diese verbindungen enthaltende arzneimittel
JPH075594B2 (ja) * 1986-03-25 1995-01-25 三井石油化学工業株式会社 新規ピリドピリミジン誘導体
DE3631294A1 (de) * 1986-09-13 1988-03-24 Thomae Gmbh Dr K Neue synergistische kombination bestehend aus einem phosphodiesterase-hemmer und einem thromboxan-a(pfeil abwaerts)2(pfeil abwaerts)-antagonisten und deren verwendung bzw. herstellung
DE4325900A1 (de) * 1993-08-02 1995-02-09 Thomae Gmbh Dr K Trisubstituierte Pyrimido [5,4-d] pyrimidine zur Modulation der Multidrugresistenz, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
TW414798B (en) * 1994-09-07 2000-12-11 Thomae Gmbh Dr K Pyrimido (5,4-d) pyrimidines, medicaments comprising these compounds, their use and processes for their preparation
DE19608653A1 (de) * 1996-03-06 1997-09-11 Thomae Gmbh Dr K Pyrimido[5,4-d]pyrimidine, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
DE19608588A1 (de) * 1996-03-06 1997-09-11 Thomae Gmbh Dr K Pyrimido [5,4-d]pyrimidine, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
WO2005003100A2 (en) 2003-07-03 2005-01-13 Myriad Genetics, Inc. 4-arylamino-quinazolines as activators of caspases and inducers of apoptosis
WO2006074147A2 (en) 2005-01-03 2006-07-13 Myriad Genetics, Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
US8309562B2 (en) * 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
DE102004002557A1 (de) * 2004-01-17 2005-08-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von substituierten Pyrimido(5,4-d)pyrimidinen zur Behandlung von Atemwegserkrankungen
AU2005275935A1 (en) * 2004-08-24 2006-03-02 Sumitomo Chemical Company, Limited Method for producing 2-(4-methyl-2-phenylpiperazine-1-yl)-3-cyanopiridine
US8258145B2 (en) * 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB807826A (en) * 1955-03-14 1959-01-21 Thomae Gmbh Dr K Derivatives of pyrimido[5,4-d] pyrimidine and production thereof
DE1150086B (de) * 1956-04-25 1963-06-12 Thomae Gmbh Dr K Verfahren zur Herstellung von 2-Morpholino-4, 8-bis-(3'-methoxy-propylamino)-pyrimido [5, 4-d] pyrimidin
US3031450A (en) * 1959-04-30 1962-04-24 Thomae Gmbh Dr K Substituted pyrimido-[5, 4-d]-pyrimidines
DE1168439B (de) * 1959-06-25 1964-04-23 Thomae Gmbh Dr K Verfahren zur Herstellung von Estern von Hydroxyalkylamino-pyrimido [5, 4-d] pyrimidinen
FR1292943A (fr) * 1960-04-27 1962-05-11 Thomae Gmbh Dr K Procédé pour la fabrication de dérivés de la pyrimido-[5, 4-d]-pyrimidine
GB1051218A (fi) * 1963-03-09
US3322755A (en) * 1964-03-10 1967-05-30 Boehringer Sohn Ingelheim Basic-substituted 1, 2, 3, 4-tetrahydropyrimido [5, 4-d]-pyrimidines
DE3069211D1 (en) * 1979-07-03 1984-10-25 Thomae Gmbh Dr K 2-(perhydro-1,4-diazino)-pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them

Also Published As

Publication number Publication date
EP0055444B1 (de) 1985-03-20
ES8300768A1 (es) 1982-11-01
IL64647A0 (en) 1982-03-31
FI71151C (fi) 1986-11-24
ZA818934B (en) 1983-09-28
NO158256C (no) 1988-08-10
IL64647A (en) 1985-10-31
NO814299L (no) 1982-06-28
NZ199376A (en) 1985-12-13
GB2090833A (en) 1982-07-21
AU547792B2 (en) 1985-11-07
PH22243A (en) 1988-07-01
GB2090833B (en) 1984-10-31
PT74199B (de) 1984-01-05
GR76356B (fi) 1984-08-06
AU7904181A (en) 1982-07-08
EP0055444A2 (de) 1982-07-07
NO158256B (no) 1988-05-02
IE813078L (en) 1982-06-27
US4478833A (en) 1984-10-23
CA1176247A (en) 1984-10-16
JPS57134485A (en) 1982-08-19
ATE12232T1 (de) 1985-04-15
FI71151B (fi) 1986-08-14
ES508343A0 (es) 1982-11-01
DE3169480D1 (en) 1985-04-25
EP0055444A3 (en) 1982-08-04
PT74199A (de) 1982-01-01
IE52323B1 (en) 1987-09-16
DE3049207A1 (de) 1982-07-29
DK548981A (da) 1982-06-28

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: DR. KARL THOMAE GESELLSCHAFT MIT