JPS57134485A - Trisubstituted pyrimidopyrimidine - Google Patents

Trisubstituted pyrimidopyrimidine

Info

Publication number
JPS57134485A
JPS57134485A JP56216100A JP21610081A JPS57134485A JP S57134485 A JPS57134485 A JP S57134485A JP 56216100 A JP56216100 A JP 56216100A JP 21610081 A JP21610081 A JP 21610081A JP S57134485 A JPS57134485 A JP S57134485A
Authority
JP
Japan
Prior art keywords
optionally substituted
pyrimidopyrimidine
trisubstituted
compounds
imino group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56216100A
Other languages
English (en)
Inventor
Rotsukusu Yozefu
Muyuuraa Eritsuhi
Naaru Berutoruto
Nitsukuru Yozefu
Haaruman Barutaa
Buiizenbaagaa Yo Makushimirian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of JPS57134485A publication Critical patent/JPS57134485A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
JP56216100A 1980-12-27 1981-12-25 Trisubstituted pyrimidopyrimidine Pending JPS57134485A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803049207 DE3049207A1 (de) 1980-12-27 1980-12-27 Neue trisubstituierte pyrimido (5,4-d) pyrimidine, ihre herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
JPS57134485A true JPS57134485A (en) 1982-08-19

Family

ID=6120399

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56216100A Pending JPS57134485A (en) 1980-12-27 1981-12-25 Trisubstituted pyrimidopyrimidine

Country Status (19)

Country Link
US (1) US4478833A (ja)
EP (1) EP0055444B1 (ja)
JP (1) JPS57134485A (ja)
AT (1) ATE12232T1 (ja)
AU (1) AU547792B2 (ja)
CA (1) CA1176247A (ja)
DE (2) DE3049207A1 (ja)
DK (1) DK548981A (ja)
ES (1) ES8300768A1 (ja)
FI (1) FI71151C (ja)
GB (1) GB2090833B (ja)
GR (1) GR76356B (ja)
IE (1) IE52323B1 (ja)
IL (1) IL64647A (ja)
NO (1) NO158256C (ja)
NZ (1) NZ199376A (ja)
PH (1) PH22243A (ja)
PT (1) PT74199B (ja)
ZA (1) ZA818934B (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6115883A (ja) * 1984-06-22 1986-01-23 ドクトル．カール　トーナー　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツンク 新規ピリミド‐ピリミジン化合物
JPS62221686A (ja) * 1986-03-25 1987-09-29 Mitsui Petrochem Ind Ltd 新規ピリドピリミジン誘導体
JP2007517827A (ja) * 2004-01-17 2007-07-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患の治療のための置換ピリミド［５，４−ｄ］ピリミジンの使用

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3631294A1 (de) * 1986-09-13 1988-03-24 Thomae Gmbh Dr K Neue synergistische kombination bestehend aus einem phosphodiesterase-hemmer und einem thromboxan-a(pfeil abwaerts)2(pfeil abwaerts)-antagonisten und deren verwendung bzw. herstellung
DE4325900A1 (de) * 1993-08-02 1995-02-09 Thomae Gmbh Dr K Trisubstituierte Pyrimido [5,4-d] pyrimidine zur Modulation der Multidrugresistenz, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
TW414798B (en) * 1994-09-07 2000-12-11 Thomae Gmbh Dr K Pyrimido (5,4-d) pyrimidines, medicaments comprising these compounds, their use and processes for their preparation
DE19608653A1 (de) * 1996-03-06 1997-09-11 Thomae Gmbh Dr K Pyrimido[5,4-d]pyrimidine, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
DE19608588A1 (de) * 1996-03-06 1997-09-11 Thomae Gmbh Dr K Pyrimido [5,4-d]pyrimidine, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
US8309562B2 (en) * 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
CA2531327A1 (en) 2003-07-03 2005-01-13 Myriad Genetics, Inc. Compounds and therapeutical use thereof
CA2576299A1 (en) * 2004-08-24 2006-03-02 Sumitomo Chemical Company, Limited Method for producing 2-(4-methyl-2-phenylpiperazine-1-yl)-3-cyanopiridine
CA2592900A1 (en) 2005-01-03 2006-07-13 Myriad Genetics Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
US8258145B2 (en) * 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB807826A (en) * 1955-03-14 1959-01-21 Thomae Gmbh Dr K Derivatives of pyrimido[5,4-d] pyrimidine and production thereof
DE1150086B (de) * 1956-04-25 1963-06-12 Thomae Gmbh Dr K Verfahren zur Herstellung von 2-Morpholino-4, 8-bis-(3'-methoxy-propylamino)-pyrimido [5, 4-d] pyrimidin
US3031450A (en) * 1959-04-30 1962-04-24 Thomae Gmbh Dr K Substituted pyrimido-[5, 4-d]-pyrimidines
DE1168439B (de) * 1959-06-25 1964-04-23 Thomae Gmbh Dr K Verfahren zur Herstellung von Estern von Hydroxyalkylamino-pyrimido [5, 4-d] pyrimidinen
FR1292943A (fr) * 1960-04-27 1962-05-11 Thomae Gmbh Dr K Procédé pour la fabrication de dérivés de la pyrimido-[5, 4-d]-pyrimidine
GB1051218A (ja) * 1963-03-09
US3322755A (en) * 1964-03-10 1967-05-30 Boehringer Sohn Ingelheim Basic-substituted 1, 2, 3, 4-tetrahydropyrimido [5, 4-d]-pyrimidines
DE3069211D1 (en) * 1979-07-03 1984-10-25 Thomae Gmbh Dr K 2-(perhydro-1,4-diazino)-pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6115883A (ja) * 1984-06-22 1986-01-23 ドクトル．カール　トーナー　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツンク 新規ピリミド‐ピリミジン化合物
JPS62221686A (ja) * 1986-03-25 1987-09-29 Mitsui Petrochem Ind Ltd 新規ピリドピリミジン誘導体
JP2007517827A (ja) * 2004-01-17 2007-07-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患の治療のための置換ピリミド［５，４−ｄ］ピリミジンの使用

Also Published As

Publication number Publication date
IE52323B1 (en) 1987-09-16
FI814148L (fi) 1982-06-28
ATE12232T1 (de) 1985-04-15
ES508343A0 (es) 1982-11-01
EP0055444B1 (de) 1985-03-20
AU7904181A (en) 1982-07-08
GB2090833B (en) 1984-10-31
IL64647A (en) 1985-10-31
ZA818934B (en) 1983-09-28
IE813078L (en) 1982-06-27
AU547792B2 (en) 1985-11-07
IL64647A0 (en) 1982-03-31
FI71151C (fi) 1986-11-24
NO158256C (no) 1988-08-10
GR76356B (ja) 1984-08-06
CA1176247A (en) 1984-10-16
US4478833A (en) 1984-10-23
PT74199A (de) 1982-01-01
ES8300768A1 (es) 1982-11-01
NZ199376A (en) 1985-12-13
NO814299L (no) 1982-06-28
DE3169480D1 (en) 1985-04-25
DK548981A (da) 1982-06-28
EP0055444A2 (de) 1982-07-07
NO158256B (no) 1988-05-02
GB2090833A (en) 1982-07-21
PT74199B (de) 1984-01-05
FI71151B (fi) 1986-08-14
EP0055444A3 (en) 1982-08-04
PH22243A (en) 1988-07-01
DE3049207A1 (de) 1982-07-29

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