DE69208400T2 - Mono- und Bis-Alkylaminoanthracycline - Google Patents
Mono- und Bis-AlkylaminoanthracyclineInfo
- Publication number
- DE69208400T2 DE69208400T2 DE69208400T DE69208400T DE69208400T2 DE 69208400 T2 DE69208400 T2 DE 69208400T2 DE 69208400 T DE69208400 T DE 69208400T DE 69208400 T DE69208400 T DE 69208400T DE 69208400 T2 DE69208400 T2 DE 69208400T2
- Authority
- DE
- Germany
- Prior art keywords
- group
- formula
- hydrogen
- hydroxy
- oso2r5
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229940045799 anthracyclines and related substance Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229930182470 glycoside Natural products 0.000 abstract 1
- 150000002338 glycosides Chemical class 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- -1 nitro, amino, methoxy Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919114549A GB9114549D0 (en) | 1991-07-05 | 1991-07-05 | Mono and bis alkylamino-anthracyclines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69208400D1 DE69208400D1 (de) | 1996-03-28 |
| DE69208400T2 true DE69208400T2 (de) | 1996-06-27 |
Family
ID=10697877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69208400T Expired - Fee Related DE69208400T2 (de) | 1991-07-05 | 1992-06-30 | Mono- und Bis-Alkylaminoanthracycline |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5496808A (de) |
| EP (1) | EP0521458B1 (de) |
| JP (1) | JP3153552B2 (de) |
| KR (1) | KR100235365B1 (de) |
| CN (1) | CN1031878C (de) |
| AT (1) | ATE134376T1 (de) |
| AU (1) | AU661012B2 (de) |
| CA (1) | CA2112818C (de) |
| CZ (1) | CZ2494A3 (de) |
| DE (1) | DE69208400T2 (de) |
| FI (1) | FI106204B (de) |
| GB (1) | GB9114549D0 (de) |
| GR (1) | GR3019429T3 (de) |
| HK (1) | HK1006460A1 (de) |
| HU (1) | HU218913B (de) |
| IE (1) | IE76921B1 (de) |
| IL (1) | IL102409A (de) |
| MX (1) | MX9203928A (de) |
| NO (1) | NO300099B1 (de) |
| NZ (1) | NZ243450A (de) |
| RU (1) | RU2118328C1 (de) |
| TW (1) | TW201753B (de) |
| WO (1) | WO1993001201A1 (de) |
| ZA (1) | ZA924971B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9325420D0 (en) * | 1993-12-13 | 1994-02-16 | Erba Carlo Spa | 4'-o-sulfonyl-anthracycline derivatives |
| EP0781140A4 (de) * | 1994-09-12 | 1999-11-03 | Univ Pennsylvania | Die corticotropinfreisetzung inhibierender faktor und verfahren zu seiner nutzung |
| EP0768317B1 (de) * | 1995-10-16 | 1999-01-27 | Kyowa Hakko Kogyo Co., Ltd. | UCK14-Verbindungen |
| DE19548474A1 (de) * | 1995-12-22 | 1997-06-26 | Wacker Chemie Gmbh | Aliphatisch ungesättigte Reste aufweisende Organopolysiloxane, deren Herstellung und deren Verwendung in vernetzbaren Massen |
| GB9613433D0 (en) * | 1996-06-26 | 1996-08-28 | Pharmacia Spa | Fluoro labelled anthracyclinone and anthracycline derivatives |
| AU6150498A (en) * | 1997-02-07 | 1998-08-26 | Wistar Institute, The | Methods and compositions for the inhibition of interleukin-12 production |
| GB9806324D0 (en) * | 1998-03-24 | 1998-05-20 | Pharmacia & Upjohn Spa | Antitumour synergetic composition |
| GB9904386D0 (en) * | 1999-02-25 | 1999-04-21 | Pharmacia & Upjohn Spa | Antitumour synergistic composition |
| GB9904387D0 (en) * | 1999-02-25 | 1999-04-21 | Pharmacia & Upjohn Spa | Antitumour synergistic composition |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU570439B2 (en) * | 1983-03-28 | 1988-03-17 | Compression Labs, Inc. | A combined intraframe and interframe transform coding system |
| US4591637A (en) * | 1985-01-17 | 1986-05-27 | Sri International | Open chain-morpholino adriamycins |
| FR2591599B1 (fr) * | 1985-12-17 | 1988-08-05 | Hoechst Lab | Nouvelles anthracyclines et medicaments les contenant |
| DE3842836A1 (de) * | 1988-12-20 | 1990-06-21 | Behringwerke Ag | Rhodomycine mit einer modifizierten kohlenhydrat-einheit |
-
1991
- 1991-07-05 GB GB919114549A patent/GB9114549D0/en active Pending
-
1992
- 1992-06-26 US US07/904,650 patent/US5496808A/en not_active Expired - Fee Related
- 1992-06-30 DE DE69208400T patent/DE69208400T2/de not_active Expired - Fee Related
- 1992-06-30 AT AT92111054T patent/ATE134376T1/de active
- 1992-06-30 EP EP92111054A patent/EP0521458B1/de not_active Expired - Lifetime
- 1992-07-03 CZ CZ9424A patent/CZ2494A3/cs unknown
- 1992-07-03 MX MX9203928A patent/MX9203928A/es not_active IP Right Cessation
- 1992-07-03 RU RU94021658A patent/RU2118328C1/ru active
- 1992-07-03 CA CA002112818A patent/CA2112818C/en not_active Expired - Fee Related
- 1992-07-03 JP JP50195893A patent/JP3153552B2/ja not_active Expired - Fee Related
- 1992-07-03 ZA ZA924971A patent/ZA924971B/xx unknown
- 1992-07-03 KR KR1019940700015A patent/KR100235365B1/ko not_active IP Right Cessation
- 1992-07-03 HU HU9400022A patent/HU218913B/hu not_active IP Right Cessation
- 1992-07-03 AU AU22294/92A patent/AU661012B2/en not_active Ceased
- 1992-07-03 IE IE922177A patent/IE76921B1/en not_active IP Right Cessation
- 1992-07-03 IL IL10240992A patent/IL102409A/en not_active IP Right Cessation
- 1992-07-03 WO PCT/EP1992/001504 patent/WO1993001201A1/en not_active Application Discontinuation
- 1992-07-04 TW TW081105323A patent/TW201753B/zh active
- 1992-07-04 CN CN92108867A patent/CN1031878C/zh not_active Expired - Fee Related
- 1992-07-06 NZ NZ243450A patent/NZ243450A/en unknown
-
1994
- 1994-01-03 FI FI940011A patent/FI106204B/fi active
- 1994-01-04 NO NO940026A patent/NO300099B1/no not_active IP Right Cessation
-
1996
- 1996-03-27 GR GR960400814T patent/GR3019429T3/el unknown
-
1998
- 1998-06-19 HK HK98105711A patent/HK1006460A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: PHARMACIA & UPJOHN S.P.A., MAILAND/MILANO, IT |
|
| 8339 | Ceased/non-payment of the annual fee |