DE69131826T2 - Zwischenprodukte für 1-Carbacephalosporin und Verfahren zur Herstellung dieser - Google Patents

Zwischenprodukte für 1-Carbacephalosporin und Verfahren zur Herstellung dieser

Info

Publication number
DE69131826T2
DE69131826T2 DE69131826T DE69131826T DE69131826T2 DE 69131826 T2 DE69131826 T2 DE 69131826T2 DE 69131826 T DE69131826 T DE 69131826T DE 69131826 T DE69131826 T DE 69131826T DE 69131826 T2 DE69131826 T2 DE 69131826T2
Authority
DE
Germany
Prior art keywords
intermediates
carbacephalosporin
making
disclosed
carbacephalosporins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69131826T
Other languages
English (en)
Other versions
DE69131826D1 (de
Inventor
James Abraham Aikins
Eddie Vi-Ping Tao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE69131826D1 publication Critical patent/DE69131826D1/de
Application granted granted Critical
Publication of DE69131826T2 publication Critical patent/DE69131826T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69131826T 1990-09-13 1991-09-03 Zwischenprodukte für 1-Carbacephalosporin und Verfahren zur Herstellung dieser Expired - Fee Related DE69131826T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58230290A 1990-09-13 1990-09-13

Publications (2)

Publication Number Publication Date
DE69131826D1 DE69131826D1 (de) 2000-01-13
DE69131826T2 true DE69131826T2 (de) 2000-05-25

Family

ID=24328615

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69131826T Expired - Fee Related DE69131826T2 (de) 1990-09-13 1991-09-03 Zwischenprodukte für 1-Carbacephalosporin und Verfahren zur Herstellung dieser

Country Status (12)

Country Link
EP (1) EP0479431B1 (de)
JP (1) JP3051509B2 (de)
KR (1) KR0180904B1 (de)
AT (1) ATE187452T1 (de)
CA (1) CA2050993C (de)
DE (1) DE69131826T2 (de)
DK (1) DK0479431T3 (de)
ES (1) ES2140384T3 (de)
GR (1) GR3032665T3 (de)
HU (1) HUT59091A (de)
IE (1) IE913187A1 (de)
IL (1) IL99380A (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2559486B1 (fr) * 1984-02-13 1988-02-12 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation et leur application comme medicaments
US4665171A (en) * 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics
US4734498A (en) * 1986-07-10 1988-03-29 Eli Lilly And Company 3β-succinimidoazetidinones as chiral intermediates
US4931556A (en) * 1988-10-17 1990-06-05 Eli Lilly And Company Method of resolving cis 3-amino-4-(2-(2-furyl)eth-1-yl)-methoxycarbonylmethyl-azetidin-2-one and malic acid salts thereof

Also Published As

Publication number Publication date
HU912922D0 (en) 1992-01-28
IL99380A0 (en) 1992-08-18
DK0479431T3 (da) 2000-03-27
KR920006352A (ko) 1992-04-27
KR0180904B1 (ko) 1999-04-01
IL99380A (en) 1997-01-10
CA2050993A1 (en) 1992-03-14
EP0479431B1 (de) 1999-12-08
DE69131826D1 (de) 2000-01-13
ATE187452T1 (de) 1999-12-15
GR3032665T3 (en) 2000-06-30
JP3051509B2 (ja) 2000-06-12
JPH04257559A (ja) 1992-09-11
EP0479431A1 (de) 1992-04-08
ES2140384T3 (es) 2000-03-01
CA2050993C (en) 2002-10-01
IE913187A1 (en) 1992-02-25
HUT59091A (en) 1992-04-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee