ES2140384T3 - Intermedios para 1-carbacefalosporinas y procedimiento para su preparacion. - Google Patents

Intermedios para 1-carbacefalosporinas y procedimiento para su preparacion.

Info

Publication number
ES2140384T3
ES2140384T3 ES91308054T ES91308054T ES2140384T3 ES 2140384 T3 ES2140384 T3 ES 2140384T3 ES 91308054 T ES91308054 T ES 91308054T ES 91308054 T ES91308054 T ES 91308054T ES 2140384 T3 ES2140384 T3 ES 2140384T3
Authority
ES
Spain
Prior art keywords
intermediates
carbacefalosporinas
procedure
preparation
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91308054T
Other languages
English (en)
Inventor
James Abraham Aikins
Eddie Vi-Ping Tao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2140384T3 publication Critical patent/ES2140384T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

SE PRESENTA UN PROCESO QUE USA LA HIDROLISIS Y LA HIDROGENACION PARA CONVERTIR (BETA)-LACTAMOS EN SUS SALES ACIDAS DEL ESTER DE ALQUIL SATURADO, INTERMEDIARIOS CLAVES PARA LA 1-CARBACEFALOSPORINA. TAMBIEN SE PRESENTAN LOS INTERMEDIARIOS QUE RESULTAN DEL PROCESO.
ES91308054T 1990-09-13 1991-09-03 Intermedios para 1-carbacefalosporinas y procedimiento para su preparacion. Expired - Lifetime ES2140384T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58230290A 1990-09-13 1990-09-13

Publications (1)

Publication Number Publication Date
ES2140384T3 true ES2140384T3 (es) 2000-03-01

Family

ID=24328615

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91308054T Expired - Lifetime ES2140384T3 (es) 1990-09-13 1991-09-03 Intermedios para 1-carbacefalosporinas y procedimiento para su preparacion.

Country Status (12)

Country Link
EP (1) EP0479431B1 (es)
JP (1) JP3051509B2 (es)
KR (1) KR0180904B1 (es)
AT (1) ATE187452T1 (es)
CA (1) CA2050993C (es)
DE (1) DE69131826T2 (es)
DK (1) DK0479431T3 (es)
ES (1) ES2140384T3 (es)
GR (1) GR3032665T3 (es)
HU (1) HUT59091A (es)
IE (1) IE913187A1 (es)
IL (1) IL99380A (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2559486B1 (fr) * 1984-02-13 1988-02-12 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation et leur application comme medicaments
US4665171A (en) * 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics
US4734498A (en) * 1986-07-10 1988-03-29 Eli Lilly And Company 3β-succinimidoazetidinones as chiral intermediates
US4931556A (en) * 1988-10-17 1990-06-05 Eli Lilly And Company Method of resolving cis 3-amino-4-(2-(2-furyl)eth-1-yl)-methoxycarbonylmethyl-azetidin-2-one and malic acid salts thereof

Also Published As

Publication number Publication date
EP0479431A1 (en) 1992-04-08
HU912922D0 (en) 1992-01-28
IL99380A (en) 1997-01-10
KR920006352A (ko) 1992-04-27
EP0479431B1 (en) 1999-12-08
IE913187A1 (en) 1992-02-25
HUT59091A (en) 1992-04-28
DE69131826T2 (de) 2000-05-25
ATE187452T1 (de) 1999-12-15
DE69131826D1 (de) 2000-01-13
IL99380A0 (en) 1992-08-18
CA2050993A1 (en) 1992-03-14
JPH04257559A (ja) 1992-09-11
GR3032665T3 (en) 2000-06-30
CA2050993C (en) 2002-10-01
DK0479431T3 (da) 2000-03-27
JP3051509B2 (ja) 2000-06-12
KR0180904B1 (ko) 1999-04-01

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