DE69127687T2 - Verfahren zur Herstellung von Nepinolon - Google Patents

Verfahren zur Herstellung von Nepinolon

Info

Publication number
DE69127687T2
DE69127687T2 DE69127687T DE69127687T DE69127687T2 DE 69127687 T2 DE69127687 T2 DE 69127687T2 DE 69127687 T DE69127687 T DE 69127687T DE 69127687 T DE69127687 T DE 69127687T DE 69127687 T2 DE69127687 T2 DE 69127687T2
Authority
DE
Germany
Prior art keywords
preparation
piperidine
nepinolone
methyl
nepinalone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69127687T
Other languages
English (en)
Other versions
DE69127687D1 (de
Inventor
Franco Tenconi
Silvana Furfaro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioindustria Farmaceutici SRL
Original Assignee
BIOINDUSTRIA SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIOINDUSTRIA SpA filed Critical BIOINDUSTRIA SpA
Application granted granted Critical
Publication of DE69127687D1 publication Critical patent/DE69127687D1/de
Publication of DE69127687T2 publication Critical patent/DE69127687T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C07D295/116—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings with the doubly bound oxygen or sulfur atoms directly attached to a carbocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69127687T 1991-04-05 1991-11-11 Verfahren zur Herstellung von Nepinolon Expired - Fee Related DE69127687T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI910952A IT1245709B (it) 1991-04-05 1991-04-05 Procedimento per la preparazione del nepinalone

Publications (2)

Publication Number Publication Date
DE69127687D1 DE69127687D1 (de) 1997-10-23
DE69127687T2 true DE69127687T2 (de) 1998-01-15

Family

ID=11359472

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69127687T Expired - Fee Related DE69127687T2 (de) 1991-04-05 1991-11-11 Verfahren zur Herstellung von Nepinolon

Country Status (8)

Country Link
EP (1) EP0507001B1 (de)
AT (1) ATE158284T1 (de)
DE (1) DE69127687T2 (de)
DK (1) DK0507001T3 (de)
ES (1) ES2106756T3 (de)
GR (1) GR3025664T3 (de)
HK (1) HK1003138A1 (de)
IT (1) IT1245709B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102266334A (zh) * 2010-06-04 2011-12-07 北京阜康仁生物制药科技有限公司 含有高纯度奈哌那隆的药用制剂
CN106397158A (zh) * 2016-08-31 2017-02-15 海门华祥医药科技有限公司 一种β‑萘氢酮的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1140990A (en) * 1967-05-05 1969-01-22 Warner Lambert Pharmaceutical Novel 1,2,3,4-tetrahydro-naphthalen-2-ones and a process for the preparation thereof

Also Published As

Publication number Publication date
HK1003138A1 (en) 1998-10-09
ES2106756T3 (es) 1997-11-16
IT1245709B (it) 1994-10-14
EP0507001B1 (de) 1997-09-17
DK0507001T3 (da) 1998-05-11
ATE158284T1 (de) 1997-10-15
GR3025664T3 (en) 1998-03-31
EP0507001A1 (de) 1992-10-07
ITMI910952A0 (it) 1991-04-05
DE69127687D1 (de) 1997-10-23
ITMI910952A1 (it) 1992-10-05

Similar Documents

Publication Publication Date Title
ATE162529T1 (de) Verfahren zur herstellung von verbrückten, chiralen metallocenkatalysatoren des types bisindenyl
DE59409435D1 (de) Verfahren zur Herstellung von 3-Arylbenzofuranonen
DE69226590T2 (de) Verfahren zur Herstellung von substituierten N-Aryl-1,2,4-Triazolopyrimidin-2-Sulfonamiden
ATE172188T1 (de) Verfahren zur herstellung von aliphatischen iminen
DE69127687T2 (de) Verfahren zur Herstellung von Nepinolon
ATE176783T1 (de) Verfahren zur herstellung von urethangruppen enthaltende bisoxazolidinen
DE3889772T2 (de) Verfahren zur Herstellung von 3,3-Diarylacrylsäureamiden.
FI885498A0 (fi) Menetelmä isotiatsolonien valmistamiseksi
DE59307005D1 (de) Verfahren zur Herstellung von Ph3C[B(C6F5)4]
NO178231C (no) Umettede polyesterharpiksblandinger og anvendelse av disse
DE69705802D1 (de) Verfahren zur Herstellung von 4-Amino-1,2,4-Triazolen
DE69410073T2 (de) Verfahren zur Herstellung von 2-Perfluoroalkyl-3-oxazolin-5-one
DE59309077D1 (de) Verfahren zur Herstellung von 2-Halogen-4,6-dialkoxypyrimidinen
DE69332707D1 (de) Verfahren zur Herstellung von 3-Vinylcephalosporinen
DE69324193T2 (de) Verfahren zur Herstellung von Enantiomeren von Dropropizin
DE69406382D1 (de) Verfahren zur Herstellung von N-Phenyl-N-(4-Piperidinyl)Amid-Derivaten
ATE114303T1 (de) Verfahren zur herstellung von perpropionsäure.
ATE92481T1 (de) Verfahren zur herstellung von n,n'-bis-(2hydroxyethyl)-piperazin.
TH37374A (th) N-t-บิวทิล-แอนดรอสท-3,5-ไดอีน-17(สูตร)-คาร์บอกซามีด-3-คาร์บอกซิลิค แอซิด พอลิมอร์ฟ
DE69611136D1 (de) Verfahren zur Herstellung von optisch aktivem (S)-(-)- und (R)-(+)- Deoxyspergualin und Zwischenprodukte dafür
TH37374EX (th) N-t-บิวทิล-แอนดรอสท-3,5-ไดอีน-17(สูตร)-คาร์บอกซามีด-3-คาร์บอกซิลิค แอซิด พอลิมอร์ฟ

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BIOINDUSTRIA FARMACEUTICI S.R.L., LATINA, IT

8339 Ceased/non-payment of the annual fee