DE69120342T2 - Selektives Hybridisierungssystem, das Q-beta-Replicase verwendet, ein Hybridisierungstest und ein Verfahren zum Nukleinsäurenachweis und zur Schätzung der Zielnukleinsäurekonzentration in flüssigen Proben - Google Patents

Selektives Hybridisierungssystem, das Q-beta-Replicase verwendet, ein Hybridisierungstest und ein Verfahren zum Nukleinsäurenachweis und zur Schätzung der Zielnukleinsäurekonzentration in flüssigen Proben

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Publication number
DE69120342T2
DE69120342T2 DE69120342T DE69120342T DE69120342T2 DE 69120342 T2 DE69120342 T2 DE 69120342T2 DE 69120342 T DE69120342 T DE 69120342T DE 69120342 T DE69120342 T DE 69120342T DE 69120342 T2 DE69120342 T2 DE 69120342T2
Authority
DE
Germany
Prior art keywords
nucleic acid
beta replicase
estimating
rna
liquid samples
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69120342T
Other languages
English (en)
Other versions
DE69120342D1 (de
Inventor
James E Stefano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gene Trak Systems Corp
Original Assignee
Gene Trak Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gene Trak Systems Corp filed Critical Gene Trak Systems Corp
Application granted granted Critical
Publication of DE69120342D1 publication Critical patent/DE69120342D1/de
Publication of DE69120342T2 publication Critical patent/DE69120342T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Treating Waste Gases (AREA)
  • Amplifiers (AREA)
DE69120342T 1990-04-25 1991-04-25 Selektives Hybridisierungssystem, das Q-beta-Replicase verwendet, ein Hybridisierungstest und ein Verfahren zum Nukleinsäurenachweis und zur Schätzung der Zielnukleinsäurekonzentration in flüssigen Proben Expired - Fee Related DE69120342T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51416190A 1990-04-25 1990-04-25
US51451890A 1990-04-25 1990-04-25

Publications (2)

Publication Number Publication Date
DE69120342D1 DE69120342D1 (de) 1996-07-25
DE69120342T2 true DE69120342T2 (de) 1996-12-19

Family

ID=27058117

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69120342T Expired - Fee Related DE69120342T2 (de) 1990-04-25 1991-04-25 Selektives Hybridisierungssystem, das Q-beta-Replicase verwendet, ein Hybridisierungstest und ein Verfahren zum Nukleinsäurenachweis und zur Schätzung der Zielnukleinsäurekonzentration in flüssigen Proben

Country Status (6)

Country Link
EP (1) EP0454461B1 (de)
JP (1) JP3240151B2 (de)
AT (1) ATE139575T1 (de)
AU (1) AU7526791A (de)
CA (1) CA2040503A1 (de)
DE (1) DE69120342T2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2108748T3 (es) * 1990-12-31 1998-01-01 Promega Corp Amplificacion de acidos nucleicos con actividad de rna polimerasa dependiente de dna, de rna replicasas.
US5464744A (en) * 1992-09-24 1995-11-07 Norval B. Galloway Methods and compositions for reducing false positive signals in an RNA amplification system
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
AU2379000A (en) 1999-12-22 2001-07-03 Procter & Gamble Company, The Disposable garment comprising meltblown nonwoven backsheet
IL160229A0 (en) 2001-08-10 2004-07-25 Genset Sa Polynucleotides, polypeptides encoded thereby and their use
EP1711517A4 (de) 2004-01-21 2008-02-13 Univ Utah Res Found MUTANTER NATRIUMKANAL NAv1.7 UND DAMIT VERBUNDENE VERFAHREN
WO2011084685A2 (en) 2009-12-17 2011-07-14 Children's Medical Center Corporation Saposin-a derived peptides and uses thereof
JP2013545439A (ja) 2010-09-17 2013-12-26 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 多能性幹細胞の有用性および安全性の特徴決定を行うための機能的ゲノミクスアッセイ
WO2013003112A1 (en) 2011-06-27 2013-01-03 The Jackson Laboratory Methods and compositions for treatment of cancer and autoimmune disease
US10378060B2 (en) 2011-10-14 2019-08-13 Dana-Farber Cancer Institute, Inc. ZNF365/ZFP365 biomarker predictive of anti-cancer response
WO2014200905A2 (en) 2013-06-10 2014-12-18 President And Fellows Of Harvard College Early developmental genomic assay for characterizing pluripotent stem cell utility and safety
WO2014205374A1 (en) 2013-06-20 2014-12-24 The Trustees Of The University Of Pennsylvania Methods for diagnosing pancreatic cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1339981C (en) * 1984-05-25 1998-08-04 Fred R. Kramer Replicatable hybridizable recombinant rna probes and methods of using same
JP3276955B2 (ja) * 1988-09-30 2002-04-22 ジーン−トラック・システムス Ｒｎａの鋳型の末端に結合したプローブ構造およびその使用方法

Also Published As

Publication number Publication date
CA2040503A1 (en) 1991-10-26
EP0454461A1 (de) 1991-10-30
ATE139575T1 (de) 1996-07-15
JP3240151B2 (ja) 2001-12-17
EP0454461B1 (de) 1996-06-19
DE69120342D1 (de) 1996-07-25
JPH04234999A (ja) 1992-08-24
AU7526791A (en) 1991-11-07

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