DE60123448D1 - Verfahren zur nicht-invasiven Diagnose von Transplantationen und Transfusionen - Google Patents

Verfahren zur nicht-invasiven Diagnose von Transplantationen und Transfusionen

Info

Publication number
DE60123448D1
DE60123448D1 DE60123448T DE60123448T DE60123448D1 DE 60123448 D1 DE60123448 D1 DE 60123448D1 DE 60123448 T DE60123448 T DE 60123448T DE 60123448 T DE60123448 T DE 60123448T DE 60123448 D1 DE60123448 D1 DE 60123448D1
Authority
DE
Germany
Prior art keywords
mtdna
donor
recipient
tissue damage
polymorphisms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60123448T
Other languages
English (en)
Other versions
DE60123448T2 (de
Inventor
Wolfgang Prof Holzgreve
Sinuhe Dr Hahn
Hendrikus Stephanus Garritsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HAHN SINUEH
Original Assignee
HAHN SINUEH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HAHN SINUEH filed Critical HAHN SINUEH
Application granted granted Critical
Publication of DE60123448D1 publication Critical patent/DE60123448D1/de
Publication of DE60123448T2 publication Critical patent/DE60123448T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Electrotherapy Devices (AREA)
DE60123448T 2001-12-24 2001-12-24 Verfahren zur nicht-invasiven Diagnose von Transplantationen und Transfusionen Expired - Fee Related DE60123448T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01811266A EP1325963B1 (de) 2001-12-24 2001-12-24 Verfahren zur nicht-invasiven Diagnose von Transplantationen und Transfusionen

Publications (2)

Publication Number Publication Date
DE60123448D1 true DE60123448D1 (de) 2006-11-09
DE60123448T2 DE60123448T2 (de) 2007-08-23

Family

ID=8184336

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60123448T Expired - Fee Related DE60123448T2 (de) 2001-12-24 2001-12-24 Verfahren zur nicht-invasiven Diagnose von Transplantationen und Transfusionen

Country Status (4)

Country Link
EP (1) EP1325963B1 (de)
AT (1) ATE340871T1 (de)
DE (1) DE60123448T2 (de)
ES (1) ES2274861T3 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1652935A1 (de) * 2004-10-29 2006-05-03 PrimaGen Holding B.V. Verfahren zur Bestimmung des Gesundheitsstatus eines Individuums durch die Verwendung von mitochondrialen Nukleinsäuren
EP1807532B1 (de) 2004-10-29 2015-03-11 PrimaGen Holding B.V. Verfahren zur bestimmung des gesundheitsstatus eines individuums durch die verwendung von mitochondrialen nukleinsäuren
US9424392B2 (en) 2005-11-26 2016-08-23 Natera, Inc. System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
US11111544B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
DK2496720T3 (da) 2009-11-06 2020-09-28 Univ Leland Stanford Junior Ikke-invasiv diagnose af transplantatafstødning i organ-transplanterede patienter
US11332785B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11408031B2 (en) 2010-05-18 2022-08-09 Natera, Inc. Methods for non-invasive prenatal paternity testing
EP2854057B1 (de) 2010-05-18 2018-03-07 Natera, Inc. Verfahren zur nichtinvasiven pränatalen Ploidiezuordnung
US11339429B2 (en) 2010-05-18 2022-05-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US11326208B2 (en) 2010-05-18 2022-05-10 Natera, Inc. Methods for nested PCR amplification of cell-free DNA
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US11332793B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for simultaneous amplification of target loci
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
JP6153874B2 (ja) 2011-02-09 2017-06-28 ナテラ, インコーポレイテッド 非侵襲的出生前倍数性呼び出しのための方法
US10072294B2 (en) * 2011-02-22 2018-09-11 City Of Hope Ultra-high sensitive monitoring of early transplantation failure
AU2012321053B2 (en) * 2011-10-07 2018-04-19 Murdoch Childrens Research Institute Diagnostic assay for tissue transplantation status
CA3209140A1 (en) 2012-04-19 2013-10-24 The Medical College Of Wisconsin, Inc. Highly sensitive surveillance using detection of cell free dna
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
ES2704682T5 (es) 2013-05-29 2023-11-10 Chronix Biomedical Detección y cuantificación de ADN extracelular del donante en la circulación de receptores de trasplantes de órganos
CN106460070B (zh) 2014-04-21 2021-10-08 纳特拉公司 检测染色体片段中的突变和倍性
CA2984352A1 (en) * 2015-04-30 2016-11-03 Aoy Tomita Mitchell Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing cell-free dna
EP4428863A2 (de) 2015-05-11 2024-09-11 Natera, Inc. Verfahren und zusammensetzungen zur bestimmung der ploidie
US11485996B2 (en) 2016-10-04 2022-11-01 Natera, Inc. Methods for characterizing copy number variation using proximity-litigation sequencing
US20190360033A1 (en) * 2016-11-02 2019-11-28 The Medical College Of Wisconsin, Inc. Methods for assessing risk using mismatch amplification and statistical methods
US10011870B2 (en) 2016-12-07 2018-07-03 Natera, Inc. Compositions and methods for identifying nucleic acid molecules
WO2018223188A1 (en) * 2017-06-06 2018-12-13 Murdoch Childrens Research Institute Assay
US11773434B2 (en) 2017-06-20 2023-10-03 The Medical College Of Wisconsin, Inc. Assessing transplant complication risk with total cell-free DNA
US12084720B2 (en) 2017-12-14 2024-09-10 Natera, Inc. Assessing graft suitability for transplantation
CA3090426A1 (en) 2018-04-14 2019-10-17 Natera, Inc. Methods for cancer detection and monitoring by means of personalized detection of circulating tumor dna
US11525159B2 (en) 2018-07-03 2022-12-13 Natera, Inc. Methods for detection of donor-derived cell-free DNA
US11931674B2 (en) 2019-04-04 2024-03-19 Natera, Inc. Materials and methods for processing blood samples

Also Published As

Publication number Publication date
EP1325963B1 (de) 2006-09-27
EP1325963A1 (de) 2003-07-09
DE60123448T2 (de) 2007-08-23
ES2274861T3 (es) 2007-06-01
ATE340871T1 (de) 2006-10-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee