DE69101792T2 - Feste und poröse Einzeldosisform, enthaltend Perlpartikel und Verfahren zu ihrer Herstellung. - Google Patents

Feste und poröse Einzeldosisform, enthaltend Perlpartikel und Verfahren zu ihrer Herstellung.

Info

Publication number
DE69101792T2
DE69101792T2 DE69101792T DE69101792T DE69101792T2 DE 69101792 T2 DE69101792 T2 DE 69101792T2 DE 69101792 T DE69101792 T DE 69101792T DE 69101792 T DE69101792 T DE 69101792T DE 69101792 T2 DE69101792 T2 DE 69101792T2
Authority
DE
Germany
Prior art keywords
mixture
solid
lyophilized
beads
mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69101792T
Other languages
German (de)
English (en)
Other versions
DE69101792D1 (de
Inventor
Anne Coutel
Guy Lebreton
Michel Veillard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farmalyoc
Original Assignee
Farmalyoc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmalyoc filed Critical Farmalyoc
Publication of DE69101792D1 publication Critical patent/DE69101792D1/de
Application granted granted Critical
Publication of DE69101792T2 publication Critical patent/DE69101792T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Glanulating (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Peptides Or Proteins (AREA)
DE69101792T 1990-01-19 1991-01-18 Feste und poröse Einzeldosisform, enthaltend Perlpartikel und Verfahren zu ihrer Herstellung. Expired - Fee Related DE69101792T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9000624A FR2657258A1 (fr) 1990-01-19 1990-01-19 Nouvelle forme unitaire, solide et poreuse comprenant des particules sous forme de perles ainsi que sa preparation.

Publications (2)

Publication Number Publication Date
DE69101792D1 DE69101792D1 (de) 1994-06-01
DE69101792T2 true DE69101792T2 (de) 1994-08-18

Family

ID=9392949

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69101792T Expired - Fee Related DE69101792T2 (de) 1990-01-19 1991-01-18 Feste und poröse Einzeldosisform, enthaltend Perlpartikel und Verfahren zu ihrer Herstellung.

Country Status (7)

Country Link
EP (1) EP0438358B1 (enExample)
JP (1) JP2912459B2 (enExample)
AT (1) ATE104847T1 (enExample)
DE (1) DE69101792T2 (enExample)
DK (1) DK0438358T3 (enExample)
ES (1) ES2063455T3 (enExample)
FR (1) FR2657258A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656283A (en) * 1995-06-08 1997-08-12 Ortho Pharmaceutical Corporation In-situ lyophilization of vaginal suppository in unit dose applicator and resultant product
DE19705538C1 (de) * 1997-02-14 1998-08-27 Goedecke Ag Verfahren zur Trennung von Wirkstoffen in festen pharmazeutischen Zubereitungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3433872A (en) * 1966-11-25 1969-03-18 Hoffmann La Roche Palatable,free-flowing,non-agglomerating caffeine powder
FR2036890B1 (enExample) 1969-04-15 1973-01-12 Orsymonde
IE45770B1 (en) 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
CA1154213A (en) * 1981-07-07 1983-09-27 Cominco Ltd. Sulfur prilling
US4793783A (en) * 1987-01-20 1988-12-27 The Dow Chemical Company Apparatus for producing prills
FR2613223B1 (fr) * 1987-04-03 1991-09-13 Biogalenique Laboratoires Forme galenique se presentant sous la forme de grains hydrosolubles, en particulier a base d'un extrait sec de ginkgo biloba, et son procede de preparation
FR2634376B1 (fr) * 1988-07-21 1992-04-17 Farmalyoc Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation

Also Published As

Publication number Publication date
DE69101792D1 (de) 1994-06-01
EP0438358A1 (fr) 1991-07-24
ATE104847T1 (de) 1994-05-15
JP2912459B2 (ja) 1999-06-28
FR2657258B1 (enExample) 1994-08-19
JPH04210912A (ja) 1992-08-03
ES2063455T3 (es) 1995-01-01
FR2657258A1 (fr) 1991-07-26
DK0438358T3 (da) 1994-06-06
EP0438358B1 (fr) 1994-04-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee