DE69024806T2 - Methode der Reinigung von Proteinen - Google Patents

Methode der Reinigung von Proteinen

Info

Publication number
DE69024806T2
DE69024806T2 DE69024806T DE69024806T DE69024806T2 DE 69024806 T2 DE69024806 T2 DE 69024806T2 DE 69024806 T DE69024806 T DE 69024806T DE 69024806 T DE69024806 T DE 69024806T DE 69024806 T2 DE69024806 T2 DE 69024806T2
Authority
DE
Germany
Prior art keywords
ions
purifying proteins
metal ions
protein
multivalent metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69024806T
Other languages
English (en)
Other versions
DE69024806T3 (de
DE69024806D1 (de
Inventor
Rainer Eketorp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Octapharma AG
Original Assignee
Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20376405&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69024806(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia AB filed Critical Pharmacia AB
Application granted granted Critical
Publication of DE69024806D1 publication Critical patent/DE69024806D1/de
Publication of DE69024806T2 publication Critical patent/DE69024806T2/de
Publication of DE69024806T3 publication Critical patent/DE69024806T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Water Supply & Treatment (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Manufacturing Of Electric Cables (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69024806T 1989-06-27 1990-06-20 Methode der Reinigung von Proteinen Expired - Lifetime DE69024806T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8902317A SE500110C2 (sv) 1989-06-27 1989-06-27 Sätt att rena ett protein från därtill bundna flervärda metalljoner
PCT/SE1990/000442 WO1991000290A1 (en) 1989-06-27 1990-06-20 Method of cleansing proteins

Publications (3)

Publication Number Publication Date
DE69024806D1 DE69024806D1 (de) 1996-02-22
DE69024806T2 true DE69024806T2 (de) 1996-05-23
DE69024806T3 DE69024806T3 (de) 2004-10-07

Family

ID=20376405

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69024806T Expired - Lifetime DE69024806T3 (de) 1989-06-27 1990-06-20 Methode der Reinigung von Proteinen
DE199090917874T Pending DE484464T1 (de) 1989-06-27 1990-06-20 Methode der reinigung von proteinen.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE199090917874T Pending DE484464T1 (de) 1989-06-27 1990-06-20 Methode der reinigung von proteinen.

Country Status (13)

Country Link
US (2) US5229498A (de)
EP (1) EP0484464B2 (de)
JP (1) JPH0822873B2 (de)
AT (1) ATE132905T1 (de)
AU (1) AU632147B2 (de)
CA (1) CA2058958C (de)
DE (2) DE69024806T3 (de)
DK (1) DK0484464T4 (de)
ES (1) ES2031438T5 (de)
FI (1) FI101151B (de)
NO (1) NO300503B1 (de)
SE (1) SE500110C2 (de)
WO (1) WO1991000290A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2949846B2 (ja) * 1990-11-30 1999-09-20 吉富製薬株式会社 アルブミン製剤の保存方法
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
US5840851A (en) * 1993-07-23 1998-11-24 Plomer; J. Jeffrey Purification of hemoglobin
US5578564A (en) * 1993-07-23 1996-11-26 Somatogen, Inc. Nickel-free hemoglobin and methods for producing such hemoglobin
ES2103236B1 (es) 1996-01-30 1998-04-16 Grifols Grupo Sa Albumina humana terapeutica con baja capacidad para la fijacion de aluminio.
AT403989B (de) * 1996-09-16 1998-07-27 Immuno Ag Verfahren zur herstellung eines plasmaprotein-hältigen arzneimittels
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
US6693173B2 (en) 2000-12-26 2004-02-17 Alpha Therapeutic Corporation Method to remove citrate and aluminum from proteins
GB0117879D0 (en) 2001-07-21 2001-09-12 Common Services Agency Storage of liquid compositions
PT104861A (pt) 2009-12-07 2011-06-07 Univ Aveiro Cerâmicos produzidos a partir de escórias de incineração de resíduos sólidos
EP3500588A1 (de) 2016-08-17 2019-06-26 Boehringer Ingelheim International GmbH Verfahren zur herstellung von hochkonzentrierten flüssigen formulierungen mit biomolekülen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4116948A (en) * 1975-03-24 1978-09-26 Hellmut Mittenzwei Process for removal of inorganic salts from peptide/salt-containing substances
JPS55124719A (en) * 1979-03-22 1980-09-26 Kowa Co Preparation of immune globulin administrable by intravenous injection
US5250663A (en) 1990-04-19 1993-10-05 Miles Inc. Preparing essentially monomeric normal human serum albumin

Also Published As

Publication number Publication date
DE69024806T3 (de) 2004-10-07
AU5946490A (en) 1991-01-17
SE8902317L (sv) 1990-12-28
JPH0822873B2 (ja) 1996-03-06
ES2031438T3 (es) 1996-03-16
AU632147B2 (en) 1992-12-17
DK0484464T4 (da) 2004-05-03
FI101151B (fi) 1998-04-30
NO300503B1 (no) 1997-06-09
ES2031438T5 (es) 2004-09-16
JPH04506349A (ja) 1992-11-05
NO915101L (no) 1991-12-23
DK0484464T3 (da) 1996-02-12
EP0484464A1 (de) 1992-05-13
SE8902317D0 (sv) 1989-06-27
USRE37286E1 (en) 2001-07-17
EP0484464B2 (de) 2004-02-11
DE484464T1 (de) 1992-08-13
CA2058958A1 (en) 1990-12-28
EP0484464B1 (de) 1996-01-10
ES2031438T1 (es) 1992-12-16
ATE132905T1 (de) 1996-01-15
DE69024806D1 (de) 1996-02-22
US5229498A (en) 1993-07-20
FI916000A0 (fi) 1991-12-19
WO1991000290A1 (en) 1991-01-10
SE500110C2 (sv) 1994-04-18
NO915101D0 (no) 1991-12-23
CA2058958C (en) 2000-12-12

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: BIOVITRUM AB, STOCKHOLM, SE

8327 Change in the person/name/address of the patent owner

Owner name: OCTAPHARMA AG, LACHEN, CH

8366 Restricted maintained after opposition proceedings