DE69005959D1 - Verfahren zur Reinigung von menschlichem Serum-Albumin. - Google Patents

Verfahren zur Reinigung von menschlichem Serum-Albumin.

Info

Publication number
DE69005959D1
DE69005959D1 DE90117928T DE69005959T DE69005959D1 DE 69005959 D1 DE69005959 D1 DE 69005959D1 DE 90117928 T DE90117928 T DE 90117928T DE 69005959 T DE69005959 T DE 69005959T DE 69005959 D1 DE69005959 D1 DE 69005959D1
Authority
DE
Germany
Prior art keywords
purification
serum albumin
human serum
human
albumin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE90117928T
Other languages
English (en)
Other versions
DE69005959T2 (de
Inventor
Wataru Ohtani
Akinori Sumi
Takao Ohmura
Yahiro Uemura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17051210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69005959(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Publication of DE69005959D1 publication Critical patent/DE69005959D1/de
Application granted granted Critical
Publication of DE69005959T2 publication Critical patent/DE69005959T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69005959T 1989-09-18 1990-09-18 Verfahren zur Reinigung von menschlichem Serum-Albumin. Expired - Lifetime DE69005959T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1239877A JPH0671434B2 (ja) 1989-09-18 1989-09-18 ヒト血清アルブミンの製造方法

Publications (2)

Publication Number Publication Date
DE69005959D1 true DE69005959D1 (de) 1994-02-24
DE69005959T2 DE69005959T2 (de) 1994-06-16

Family

ID=17051210

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69005959T Expired - Lifetime DE69005959T2 (de) 1989-09-18 1990-09-18 Verfahren zur Reinigung von menschlichem Serum-Albumin.

Country Status (8)

Country Link
US (1) US5132404A (de)
EP (1) EP0420007B1 (de)
JP (1) JPH0671434B2 (de)
KR (1) KR100199523B1 (de)
CA (1) CA2025605C (de)
DE (1) DE69005959T2 (de)
DK (1) DK0420007T3 (de)
ES (1) ES2062241T3 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0671434B2 (ja) * 1989-09-18 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法
US5268273A (en) * 1990-12-14 1993-12-07 Phillips Petroleum Company Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
JPH0671432B2 (ja) * 1991-03-20 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法
CZ149294A3 (en) * 1991-12-18 1994-11-16 Icu Medical Inc Medicinal valve
US5440018A (en) * 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5521287A (en) * 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
JPH07126182A (ja) * 1993-10-27 1995-05-16 Green Cross Corp:The 組換えヒト血清アルブミン製剤の滅菌方法
EP0658569B2 (de) * 1993-12-17 2008-11-26 Mitsubishi Pharma Corporation Verfahren zum Entfärben von menschlichen Serum-Albumin
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
DE69532492T2 (de) * 1994-08-31 2004-12-02 Mitsubishi Pharma Corp. Verfahren zur Reinigung von rekombinantem menschlichem Serumalbumin
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
JP4798832B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の除去方法
JP4798833B2 (ja) * 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 加熱処理工程を含むヒト血清アルブミンの製造方法
KR100827750B1 (ko) * 2000-10-24 2008-05-07 쥬리디컬 파운데이션 더 케모-세로-쎄라퓨틱 리서치 인스티튜트 인체 혈청알부민 다량체의 단량체화 방법
JP4259324B2 (ja) * 2002-02-28 2009-04-30 ニプロ株式会社 安定化されたアルブミン製剤
EP1710250B1 (de) 2004-01-20 2009-04-15 Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute Verfahren zur herstellung von humanserumalbumin durch wärmebehandlung in gegenwart von zweiwertigem kation
MX2008008076A (es) * 2005-12-22 2008-11-28 Conjuchem Biotechnologies Inc Procesos para la produccion de conjugados preformados de albumina y un agente terapeutico.
TW201000135A (en) 2008-05-15 2010-01-01 R Tech Ueno Ltd Pharmaceutical composition for treating xerophthalmia and/or disorder of cornea/conjunctiva
KR101568360B1 (ko) 2013-08-06 2015-11-12 이화여자대학교 산학협력단 열안정화된 인간혈청알부민의 제조방법
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2444679A (en) * 1945-11-30 1948-07-06 Arthur J Shaukis Mailbox
US2765299A (en) * 1952-06-27 1956-10-02 Armour & Co Recovery of serum albumin
US3100737A (en) * 1958-02-05 1963-08-13 Auerswald Wilhelm Method of preparing a plasma protein solution free of active hepatitis virus and product produced thereby
FR2190437B1 (de) * 1972-07-05 1975-08-08 Merieux Inst
JPS5417002B2 (de) * 1974-02-18 1979-06-27
JPS5225019A (en) * 1975-08-19 1977-02-24 New Zealand Inventions Dev Production of serum albumin
JPS5312965A (en) * 1976-07-22 1978-02-06 Tatsuo Teraoka Method of manufacture of frp
DK25877A (da) * 1977-01-21 1978-08-15 Nordisk Insulinlab Fremgangsmaade til udvinding af renset albumin fra blodplasma
JPS5417002A (en) * 1977-07-07 1979-02-08 Pioneer Electronic Corp Record player
US4426323A (en) * 1980-01-10 1984-01-17 Ionics, Incorporated Selected recovery of proteins from fermentation broths
JPS5795997A (en) * 1980-12-08 1982-06-15 Nippon Sekijiyuujishiya Removal of admixed protein from albumin-containing solution in presence of water-soluble high polymer
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
US4613501A (en) * 1984-12-21 1986-09-23 New York Blood Center, Inc. Inactivation of viruses in labile blood derivatives
FR2579224B1 (fr) * 1985-03-25 1987-05-22 Genetica Procede de preparation microbiologique de la serum-albumine humaine
US4675387A (en) * 1985-07-26 1987-06-23 E. I. Du Pont De Nemours And Company Method for extracting protein with organic acid
JPS62224284A (ja) * 1986-03-25 1987-10-02 Agency Of Ind Science & Technol 微生物
GB8613388D0 (en) * 1986-06-03 1986-07-09 Delta Biotechnology Ltd Induction of galactose regulated gene expression in yeast
US4723944A (en) * 1986-06-05 1988-02-09 Jensen Ole R Fluid collection receptacle with improved non-return valve
JPS62294621A (ja) * 1986-06-13 1987-12-22 Green Cross Corp:The アルブミンの回収方法
US4841023A (en) * 1986-06-25 1989-06-20 New York Blood Center, Inc. Inactivation of viruses in labile protein-containing compositions using fatty acids
GB8615701D0 (en) * 1986-06-27 1986-08-06 Delta Biotechnology Ltd Stable gene integration vector
JPH0811074B2 (ja) * 1987-10-30 1996-02-07 財団法人化学及血清療法研究所 プレアルブミンをコードする遺伝子を組込んだ組換えプラスミドおよびこれを用いたプレアルブミンの製法
US4939176A (en) * 1988-12-20 1990-07-03 Miles Inc. Viral inactivation process
JPH0671434B2 (ja) * 1989-09-18 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法

Also Published As

Publication number Publication date
EP0420007B1 (de) 1994-01-12
CA2025605C (en) 2000-10-31
KR910006481A (ko) 1991-04-29
KR100199523B1 (ko) 1999-06-15
ES2062241T3 (es) 1994-12-16
CA2025605A1 (en) 1991-03-19
EP0420007A1 (de) 1991-04-03
US5132404A (en) 1992-07-21
DK0420007T3 (da) 1994-02-21
JPH03103188A (ja) 1991-04-30
DE69005959T2 (de) 1994-06-16
JPH0671434B2 (ja) 1994-09-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD., OSAKA,

8327 Change in the person/name/address of the patent owner

Owner name: WELFIDE CORP., OSAKA, JP

8327 Change in the person/name/address of the patent owner

Owner name: MITSUBISHI PHARMA CORP., OSAKA, JP