ES2031438T1 - Metodo de limpiar proteinas. - Google Patents

Metodo de limpiar proteinas.

Info

Publication number
ES2031438T1
ES2031438T1 ES199090917874T ES90917874T ES2031438T1 ES 2031438 T1 ES2031438 T1 ES 2031438T1 ES 199090917874 T ES199090917874 T ES 199090917874T ES 90917874 T ES90917874 T ES 90917874T ES 2031438 T1 ES2031438 T1 ES 2031438T1
Authority
ES
Spain
Prior art keywords
ions
metal ions
protein
proteins
cleaning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES199090917874T
Other languages
English (en)
Other versions
ES2031438T3 (es
ES2031438T5 (es
Inventor
Rainer Eketorp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Kabi Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20376405&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2031438(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kabi Pharmacia AB filed Critical Kabi Pharmacia AB
Publication of ES2031438T1 publication Critical patent/ES2031438T1/es
Publication of ES2031438T3 publication Critical patent/ES2031438T3/es
Application granted granted Critical
Publication of ES2031438T5 publication Critical patent/ES2031438T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Water Supply & Treatment (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Manufacturing Of Electric Cables (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA INVENCION SE REFIERE A UN METODO PARA LIMPIAR UNA PROTEINA DE LOS IONES METALICOS MULTIVALENTES ALLI UNIDOS, SIENDO EXTRAIDOS ESTOS IONES DE LA PROTEINA AL INTERCAMBIAR LOS IONES CON IONES METALICOS MONOVALENTES, POR LO QUE LOS SE EXTRAEN LOS IONES METALICOS MULTIVALENTES . LA LIBERACION Y EXTRACCION DE ESTOS IONES SE EFECTUA, EN PARTICULAR, POR DIAFILTRACION O PROCESOS DE FILTRACION DE GEL.
ES90917874T 1989-06-27 1990-06-20 Metodo para la purificacion de proteinas. Expired - Lifetime ES2031438T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8902317A SE500110C2 (sv) 1989-06-27 1989-06-27 Sätt att rena ett protein från därtill bundna flervärda metalljoner
SE8902317 1989-06-27

Publications (3)

Publication Number Publication Date
ES2031438T1 true ES2031438T1 (es) 1992-12-16
ES2031438T3 ES2031438T3 (es) 1996-03-16
ES2031438T5 ES2031438T5 (es) 2004-09-16

Family

ID=20376405

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90917874T Expired - Lifetime ES2031438T5 (es) 1989-06-27 1990-06-20 Metodo para la purificacion de proteinas.

Country Status (13)

Country Link
US (2) US5229498A (es)
EP (1) EP0484464B2 (es)
JP (1) JPH0822873B2 (es)
AT (1) ATE132905T1 (es)
AU (1) AU632147B2 (es)
CA (1) CA2058958C (es)
DE (2) DE69024806T3 (es)
DK (1) DK0484464T4 (es)
ES (1) ES2031438T5 (es)
FI (1) FI101151B (es)
NO (1) NO300503B1 (es)
SE (1) SE500110C2 (es)
WO (1) WO1991000290A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2949846B2 (ja) * 1990-11-30 1999-09-20 吉富製薬株式会社 アルブミン製剤の保存方法
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
US5840851A (en) * 1993-07-23 1998-11-24 Plomer; J. Jeffrey Purification of hemoglobin
US5578564A (en) * 1993-07-23 1996-11-26 Somatogen, Inc. Nickel-free hemoglobin and methods for producing such hemoglobin
ES2103236B1 (es) 1996-01-30 1998-04-16 Grifols Grupo Sa Albumina humana terapeutica con baja capacidad para la fijacion de aluminio.
AT403989B (de) * 1996-09-16 1998-07-27 Immuno Ag Verfahren zur herstellung eines plasmaprotein-hältigen arzneimittels
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
US6693173B2 (en) 2000-12-26 2004-02-17 Alpha Therapeutic Corporation Method to remove citrate and aluminum from proteins
GB0117879D0 (en) 2001-07-21 2001-09-12 Common Services Agency Storage of liquid compositions
PT104861A (pt) 2009-12-07 2011-06-07 Univ Aveiro Cerâmicos produzidos a partir de escórias de incineração de resíduos sólidos
EP3500588A1 (en) 2016-08-17 2019-06-26 Boehringer Ingelheim International GmbH Process for the preparation of highly concentrated liquid formulations containing biomolecules

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4116948A (en) * 1975-03-24 1978-09-26 Hellmut Mittenzwei Process for removal of inorganic salts from peptide/salt-containing substances
JPS55124719A (en) * 1979-03-22 1980-09-26 Kowa Co Preparation of immune globulin administrable by intravenous injection
US5250663A (en) 1990-04-19 1993-10-05 Miles Inc. Preparing essentially monomeric normal human serum albumin

Also Published As

Publication number Publication date
DE69024806T3 (de) 2004-10-07
AU5946490A (en) 1991-01-17
SE8902317L (sv) 1990-12-28
JPH0822873B2 (ja) 1996-03-06
ES2031438T3 (es) 1996-03-16
DE69024806T2 (de) 1996-05-23
AU632147B2 (en) 1992-12-17
DK0484464T4 (da) 2004-05-03
FI101151B (fi) 1998-04-30
NO300503B1 (no) 1997-06-09
ES2031438T5 (es) 2004-09-16
JPH04506349A (ja) 1992-11-05
NO915101L (no) 1991-12-23
DK0484464T3 (da) 1996-02-12
EP0484464A1 (en) 1992-05-13
SE8902317D0 (sv) 1989-06-27
USRE37286E1 (en) 2001-07-17
EP0484464B2 (en) 2004-02-11
DE484464T1 (de) 1992-08-13
CA2058958A1 (en) 1990-12-28
EP0484464B1 (en) 1996-01-10
ATE132905T1 (de) 1996-01-15
DE69024806D1 (de) 1996-02-22
US5229498A (en) 1993-07-20
FI916000A0 (fi) 1991-12-19
WO1991000290A1 (en) 1991-01-10
SE500110C2 (sv) 1994-04-18
NO915101D0 (no) 1991-12-23
CA2058958C (en) 2000-12-12

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