DE69017543D1 - Acetylcholinesterase-Inhibitoren. - Google Patents
Acetylcholinesterase-Inhibitoren.Info
- Publication number
- DE69017543D1 DE69017543D1 DE69017543T DE69017543T DE69017543D1 DE 69017543 D1 DE69017543 D1 DE 69017543D1 DE 69017543 T DE69017543 T DE 69017543T DE 69017543 T DE69017543 T DE 69017543T DE 69017543 D1 DE69017543 D1 DE 69017543D1
- Authority
- DE
- Germany
- Prior art keywords
- acetylcholinesterase inhibitors
- acetylcholinesterase
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000544 cholinesterase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP89401775A EP0403713A1 (de) | 1989-06-22 | 1989-06-22 | Acetylcholinesterase-Inhibitoren |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69017543D1 true DE69017543D1 (de) | 1995-04-13 |
DE69017543T2 DE69017543T2 (de) | 1995-07-06 |
Family
ID=8202963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69017543T Expired - Lifetime DE69017543T2 (de) | 1989-06-22 | 1990-06-20 | Acetylcholinesterase-Inhibitoren. |
Country Status (19)
Country | Link |
---|---|
EP (2) | EP0403713A1 (de) |
JP (1) | JP2879951B2 (de) |
KR (1) | KR0139529B1 (de) |
CN (1) | CN1027759C (de) |
AR (1) | AR247214A1 (de) |
AT (1) | ATE119535T1 (de) |
AU (1) | AU626428B2 (de) |
CA (1) | CA2019231C (de) |
DE (1) | DE69017543T2 (de) |
DK (1) | DK0409676T3 (de) |
ES (1) | ES2072406T3 (de) |
FI (1) | FI97619C (de) |
HU (1) | HU210569B (de) |
IE (1) | IE66155B1 (de) |
IL (1) | IL94779A (de) |
NO (1) | NO178374C (de) |
NZ (1) | NZ234136A (de) |
PT (1) | PT94449B (de) |
ZA (1) | ZA904715B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0611769A1 (de) * | 1993-02-16 | 1994-08-24 | Merrell Dow Pharmaceuticals Inc. | Silytierte acetylcholinesterase Inhibitoren |
US5523442A (en) * | 1993-02-16 | 1996-06-04 | Merrell Pharmaceuticals Inc. | Silylated acetylcholinesterase inhibitors |
EP0627400A1 (de) * | 1993-06-04 | 1994-12-07 | Merrell Dow Pharmaceuticals Inc. | Aromatische Inhibitoren von Acetylcholinesterase |
US5554780A (en) * | 1994-05-05 | 1996-09-10 | Merrell Pharmaceuticals Inc. | Process for the preparation of 1-(3-trialkylsilylphenyl)-2,2,2-trifluoromethyl ethanone derivatives |
US5486638A (en) * | 1994-11-08 | 1996-01-23 | Marion Merrell Dow Inc. | Process for the preparation of 1-halo-3-trialkysilanyl-benzene derivatives |
EP0749972A1 (de) | 1995-06-21 | 1996-12-27 | Merrell Pharmaceuticals Inc. | Verfahren zur Herstellung von 1-(3-trialkylsilylphenyl)-2,2,2-trifluormethylethanonderivaten |
US6673784B1 (en) | 1996-03-19 | 2004-01-06 | G. D. Searle & Co. | Electrophilic ketones for the treatment of herpesvirus infections |
CN1059702C (zh) * | 1997-12-30 | 2000-12-20 | 中国科学院上海细胞生物学研究所 | 从哺乳类细胞中获得脑型乙酰胆碱酯酶的方法 |
US6218383B1 (en) | 1998-08-07 | 2001-04-17 | Targacept, Inc. | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
US6084117A (en) * | 1999-11-22 | 2000-07-04 | Albemarle Corporation | Production of silated haloarenes by selective silylation of polyhaloarenes |
EP2533645B1 (de) | 2010-02-09 | 2016-07-27 | The Johns Hopkins University | Verfahren und zusammensetzungen zur verbesserung von kognitiven funktionen |
EP2919788A4 (de) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | Verfahren und zusammensetzungen zur behandlung von schizophrenie |
MX362886B (es) | 2012-12-13 | 2019-02-22 | H Lundbeck As | Composición sinérgica que comprende vortioxetina y donepezilo para incrementar los niveles de acetilcolina en el cerebro, y el uso de la misma en el tratamiento de una disfunción cognitiva. |
DK2968220T3 (da) | 2013-03-15 | 2021-06-14 | Agenebio Inc | Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion |
EP2968237A4 (de) | 2013-03-15 | 2016-08-31 | Univ Johns Hopkins | Verfahren und zusammensetzungen zur verbesserung der kognitiven funktion |
BR112017025031B1 (pt) | 2015-05-22 | 2023-03-21 | Agenebio, Inc | Composições farmacêuticas de liberação prolongada de levetiracetam |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL25820A (en) * | 1966-05-22 | 1971-02-25 | Yissum Res Dev Co | Silicon containing beta-hydroxy alpha-phenyl carboxylic acids,their amide and ester derivatives and intermediates for their preparation |
US4835099A (en) * | 1986-11-20 | 1989-05-30 | Becton, Dickinson And Company | Signal enhancement in immunoassay by modulation of enzymatic catalysis |
-
1989
- 1989-06-22 EP EP89401775A patent/EP0403713A1/de not_active Withdrawn
-
1990
- 1990-06-18 CA CA002019231A patent/CA2019231C/en not_active Expired - Lifetime
- 1990-06-18 ZA ZA904715A patent/ZA904715B/xx unknown
- 1990-06-19 IL IL9477990A patent/IL94779A/en not_active IP Right Cessation
- 1990-06-19 AU AU57584/90A patent/AU626428B2/en not_active Ceased
- 1990-06-19 NZ NZ234136A patent/NZ234136A/xx unknown
- 1990-06-20 FI FI903104A patent/FI97619C/fi active IP Right Grant
- 1990-06-20 EP EP90401745A patent/EP0409676B1/de not_active Expired - Lifetime
- 1990-06-20 ES ES90401745T patent/ES2072406T3/es not_active Expired - Lifetime
- 1990-06-20 HU HU903933A patent/HU210569B/hu not_active IP Right Cessation
- 1990-06-20 AR AR90317164A patent/AR247214A1/es active
- 1990-06-20 AT AT90401745T patent/ATE119535T1/de not_active IP Right Cessation
- 1990-06-20 DK DK90401745.6T patent/DK0409676T3/da active
- 1990-06-20 DE DE69017543T patent/DE69017543T2/de not_active Expired - Lifetime
- 1990-06-21 PT PT94449A patent/PT94449B/pt not_active IP Right Cessation
- 1990-06-21 NO NO902776A patent/NO178374C/no not_active IP Right Cessation
- 1990-06-21 IE IE225290A patent/IE66155B1/en not_active IP Right Cessation
- 1990-06-21 KR KR1019900009196A patent/KR0139529B1/ko not_active IP Right Cessation
- 1990-06-22 JP JP2163002A patent/JP2879951B2/ja not_active Expired - Lifetime
- 1990-06-22 CN CN90103127A patent/CN1027759C/zh not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |