DE69016691D1 - Lineare Somatostatin-Analoga. - Google Patents

Lineare Somatostatin-Analoga.

Info

Publication number
DE69016691D1
DE69016691D1 DE69016691T DE69016691T DE69016691D1 DE 69016691 D1 DE69016691 D1 DE 69016691D1 DE 69016691 T DE69016691 T DE 69016691T DE 69016691 T DE69016691 T DE 69016691T DE 69016691 D1 DE69016691 D1 DE 69016691D1
Authority
DE
Germany
Prior art keywords
phe
octapeptides
lower alkyl
ala
linear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69016691T
Other languages
English (en)
Other versions
DE69016691T2 (de
Inventor
David H Coy
William A Murphy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tulane University
Original Assignee
Tulane University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tulane University filed Critical Tulane University
Application granted granted Critical
Publication of DE69016691D1 publication Critical patent/DE69016691D1/de
Publication of DE69016691T2 publication Critical patent/DE69016691T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69016691T 1989-04-26 1990-04-26 Lineare Somatostatin-Analoga. Expired - Fee Related DE69016691T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34332589A 1989-04-26 1989-04-26

Publications (2)

Publication Number Publication Date
DE69016691D1 true DE69016691D1 (de) 1995-03-23
DE69016691T2 DE69016691T2 (de) 1995-10-05

Family

ID=23345640

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69016691T Expired - Fee Related DE69016691T2 (de) 1989-04-26 1990-04-26 Lineare Somatostatin-Analoga.

Country Status (14)

Country Link
EP (1) EP0395417B1 (de)
JP (1) JP2882679B2 (de)
KR (1) KR0173119B1 (de)
AT (1) ATE118222T1 (de)
CA (1) CA2053250A1 (de)
CZ (1) CZ284341B6 (de)
DD (1) DD293832A5 (de)
DE (1) DE69016691T2 (de)
DK (1) DK0395417T3 (de)
ES (1) ES2069684T3 (de)
HU (1) HU217636B (de)
IE (1) IE66113B1 (de)
SK (1) SK211290A3 (de)
WO (1) WO1990012811A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE920416A1 (en) * 1991-02-08 1992-08-12 Biomeasure Method of treating benign and malignant proliferative skin¹disease
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
US5716596A (en) * 1992-06-23 1998-02-10 Diatide, Inc. Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
US5871711A (en) * 1992-06-23 1999-02-16 Diatide, Inc. Radioactively-labeled somatostatin-derived peptides for imaging and therapeutic uses
US5620675A (en) * 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
CA2118588A1 (en) * 1992-07-27 1994-02-03 David H. Coy Neuromedin b receptor antagonists
US5569741A (en) * 1992-07-27 1996-10-29 Biomeasure, Inc. Cyclic octapeptide neuromedin B receptor antagonists
US5462926A (en) * 1992-07-27 1995-10-31 Biomeasure, Inc. Neuromedin B receptor antagonists which demonstrate selectivity
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
US5770687A (en) * 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
US6051554A (en) * 1995-06-07 2000-04-18 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
MY147327A (en) * 1995-06-29 2012-11-30 Novartis Ag Somatostatin peptides
JP3869874B2 (ja) * 1995-11-15 2007-01-17 大日本住友製薬株式会社 急性肝不全治療剤
US6841533B1 (en) 1995-12-07 2005-01-11 Peptor Limited Conformationally constrained backbone cyclized interleukin-6 antagonists
US5686418A (en) * 1996-04-08 1997-11-11 Biomeasure Incorporated Prolonging survival of transplanted pancreatic cells
WO1998008528A1 (en) 1996-08-30 1998-03-05 Biomeasure Incorporated Method of inhibiting fibrosis with a somatostatin agonist
US6262229B1 (en) 1996-12-04 2001-07-17 Biomeasure Incorporated Somatostatin antagonists
RU2179172C2 (ru) * 1996-12-04 2002-02-10 Сосьете Де Консей Де Решерш Э Д'Аппликасьон Сьентифик С.А. (С.К.Р.А.С.) Антагонисты рецепторов соматостатина
WO1998051331A1 (en) 1997-05-13 1998-11-19 Societe De Conseils De Recherches Et D'applications Scientifiques S.A. (S.C.R.A.S.) Somatostatin and somatostatin agonists for decreasing body weight
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
US7026289B2 (en) 1997-05-13 2006-04-11 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Method and compositions for treating hyperlipidemia and other conditions
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
US6124263A (en) * 1998-11-16 2000-09-26 Asta Medica Ag Treatment of tumors by administration of growth hormone releasing compounds and their antagonists
SE9804064D0 (sv) * 1998-11-25 1998-11-25 A & Science Invest Ab Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells
US6903074B1 (en) 1999-06-04 2005-06-07 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Neuromedin b and somatostatin receptor agonists
GB0018891D0 (en) 2000-08-01 2000-09-20 Novartis Ag Organic compounds
CN1541102A (zh) * 2001-04-09 2004-10-27 生长激素抑制素激动剂
JP3996897B2 (ja) 2001-06-08 2007-10-24 ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス ソマトスタチン−ドーパミンキメラ類似体
AU2004232314B2 (en) 2003-04-22 2007-11-22 Ipsen Pharma S.A.S. Peptide vectors
JP5799397B2 (ja) 2008-06-12 2015-10-28 イプセン・バイオイノベーション・リミテッドＩｐｓｅｎ Ｂｉｏｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ 癌の抑制
EP3590956A1 (de) 2008-06-12 2020-01-08 Ipsen Bioinnovation Limited Unterdrückung von neuroendokrinen erkrankungen
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
AU2014280847B2 (en) 2013-06-13 2019-07-04 Antisense Therapeutics Ltd Combination therapy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU78191A1 (de) * 1977-09-28 1979-05-25 Ciba Geigy Ag Verfahren zur herstellung von neuen cyclopeptiden
US4185010A (en) * 1978-12-12 1980-01-22 American Home Products Corporation Nonapeptides
US4369179A (en) * 1979-12-14 1983-01-18 Ciba-Geigy Corporation Acylpeptides
FR2567524B1 (fr) * 1984-07-10 1987-11-27 Sanofi Sa Procede de synthese de la somatocrinine en phase liquide et peptides intermediaires
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
US4871717A (en) * 1987-01-07 1989-10-03 Administrators Of The Tulane Educational Fund Peptides
JP2568228B2 (ja) * 1987-02-03 1996-12-25 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ソマトスタチンアナログ
CH679045A5 (de) * 1987-06-29 1991-12-13 Sandoz Ag
JP2809403B2 (ja) * 1987-07-07 1998-10-08 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ソマトスタチンアナログ化合物

Also Published As

Publication number Publication date
SK279231B6 (sk) 1998-08-05
CA2053250A1 (en) 1990-10-27
SK211290A3 (en) 1998-08-05
IE66113B1 (en) 1995-12-13
DD293832A5 (de) 1991-09-12
ES2069684T3 (es) 1995-05-16
HU217636B (hu) 2000-03-28
KR0173119B1 (ko) 1999-02-01
DE69016691T2 (de) 1995-10-05
HU904481D0 (en) 1992-02-28
JP2882679B2 (ja) 1999-04-12
EP0395417B1 (de) 1995-02-08
JPH04504723A (ja) 1992-08-20
DK0395417T3 (da) 1995-06-12
ATE118222T1 (de) 1995-02-15
IE901476L (en) 1990-10-26
CZ284341B6 (cs) 1998-10-14
KR920700226A (ko) 1992-02-19
HUT60287A (en) 1992-08-28
EP0395417A1 (de) 1990-10-31
CZ211290A3 (en) 1995-03-15
WO1990012811A1 (en) 1990-11-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee