DE69015999T2 - Reagenz zur Messung von Leukozyten und Hämoglobin im Blut. - Google Patents
Reagenz zur Messung von Leukozyten und Hämoglobin im Blut.Info
- Publication number
- DE69015999T2 DE69015999T2 DE69015999T DE69015999T DE69015999T2 DE 69015999 T2 DE69015999 T2 DE 69015999T2 DE 69015999 T DE69015999 T DE 69015999T DE 69015999 T DE69015999 T DE 69015999T DE 69015999 T2 DE69015999 T2 DE 69015999T2
- Authority
- DE
- Germany
- Prior art keywords
- hemoglobin
- reagent
- blood
- measuring leukocytes
- leukocytes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2525—Stabilizing or preserving
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5081390A JP2891302B2 (ja) | 1990-03-01 | 1990-03-01 | 血液中の白血球およびヘモグロビンの測定用試薬 |
JP11665890A JP2897781B2 (ja) | 1990-05-02 | 1990-05-02 | 血液中の白血球およびヘモグロビンの測定用試薬 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69015999D1 DE69015999D1 (de) | 1995-02-23 |
DE69015999T2 true DE69015999T2 (de) | 1995-06-22 |
Family
ID=26391280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69015999T Expired - Fee Related DE69015999T2 (de) | 1990-03-01 | 1990-10-23 | Reagenz zur Messung von Leukozyten und Hämoglobin im Blut. |
Country Status (4)
Country | Link |
---|---|
US (1) | US5242832A (de) |
EP (1) | EP0444241B1 (de) |
CA (1) | CA2027451C (de) |
DE (1) | DE69015999T2 (de) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5262329A (en) * | 1991-06-13 | 1993-11-16 | Carver Jr Edward L | Method for improved multiple species blood analysis |
US5284771A (en) * | 1991-12-05 | 1994-02-08 | Miles Inc. | Reagent compositions and their use in sphering cells |
JP2565844B2 (ja) * | 1992-02-07 | 1996-12-18 | アボツト・ラボラトリーズ | 細胞溶解処理条件下で異種細胞集団を正確に計数し,感受性に関する格付けを行う方法 |
DE4206932A1 (de) * | 1992-03-05 | 1993-09-09 | Boehringer Mannheim Gmbh | Immunologische methode zur bestimmung eines haemoglobinderivates |
DE69327775T2 (de) * | 1992-11-19 | 2000-06-21 | Sysmex Corp | Verfahren zur Vorbehandlung für Blutanalyse |
JP3301646B2 (ja) * | 1993-03-19 | 2002-07-15 | シスメックス株式会社 | 幼若細胞測定用試薬 |
JP3320869B2 (ja) * | 1993-12-22 | 2002-09-03 | シスメックス株式会社 | 白血球分析用試薬 |
US6242417B1 (en) * | 1994-03-08 | 2001-06-05 | Somatogen, Inc. | Stabilized compositions containing hemoglobin |
CA2183558C (en) * | 1994-03-11 | 2006-01-24 | Young Ran Kim | Cyanide-free reagent and method for the determination of hemoglobin |
JP3467310B2 (ja) * | 1994-04-21 | 2003-11-17 | シスメックス株式会社 | 白血球分析用試薬及び白血球の分類方法 |
WO1996002841A1 (en) * | 1994-07-14 | 1996-02-01 | Abbott Laboratories | Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood |
US5589327A (en) * | 1994-07-18 | 1996-12-31 | Dade International Inc. | Method and composition for the determination of red blood cell floate |
JP3355038B2 (ja) * | 1994-08-03 | 2002-12-09 | シスメックス株式会社 | 白血球分類方法 |
JP3324050B2 (ja) * | 1994-10-31 | 2002-09-17 | 日本光電工業株式会社 | 白血球分類用試薬および白血球分類方法 |
US5834315A (en) * | 1994-12-23 | 1998-11-10 | Coulter Corporation | Cyanide-free reagent and method for hemoglobin determination and leukocyte differentitation |
US5843608A (en) * | 1995-06-08 | 1998-12-01 | Coulter International Corp. | Reagent and method for differential determination of leukocytes in blood |
US5882933A (en) * | 1995-06-08 | 1999-03-16 | Coulter International Corp. | Method for determination of leukocytes and hemoglobin concentration in blood |
US5686308A (en) * | 1995-06-08 | 1997-11-11 | Coulter Corporation | Reagent and method for differential determination of leukocytes in blood |
US5786224A (en) * | 1995-06-29 | 1998-07-28 | Coulter Corporation | Reagent and method for differential determination of leukocytes in blood |
EP0794435B1 (de) * | 1996-03-07 | 2003-01-02 | Coulter International Corp. | Cyanidfreies Reagenz und Verfahren zur Bestimmung von Hämoglobin und Leukozytendifferenzierung |
US5882934A (en) * | 1997-01-21 | 1999-03-16 | Coulter International Corp. | Composition and method for hemoglobin and cell analysis |
US5763280A (en) * | 1997-01-21 | 1998-06-09 | Coulter International Corp. | Cyanide-free lytic reagent composition and method for hemoglobin and cell analysis |
JP3830613B2 (ja) * | 1997-04-18 | 2006-10-04 | シスメックス株式会社 | 血液中の白血球及びヘモグロビン濃度測定試薬 |
US5935857A (en) * | 1997-08-01 | 1999-08-10 | Coulter International Corp. | Blood diluent |
US6074881A (en) * | 1998-08-03 | 2000-06-13 | Bayer Corporation | Method for the prevention of hemoglobin interference in reagent systems for measuring peroxidase activity |
FR2782166B1 (fr) * | 1998-08-04 | 2000-10-06 | Abx Sa | Reactif pour la mesure de l'hemoglobine et la determination des leucocytes dans un echantillon de sang |
US6210969B1 (en) * | 1999-04-28 | 2001-04-03 | Coulter International Corp. | Composition and method for differentiation of basophil and eosinophil subpopulations of leukocytes in blood |
US6214625B1 (en) * | 1999-04-28 | 2001-04-10 | Coulter International Corp. | Composition and method for differentiation of basophils and eosinophils in blood |
EP1182457A1 (de) * | 2000-08-17 | 2002-02-27 | Mallinckrodt Baker B.V. | Verfahren und Reagens zur Analyse von Blutproben, im besonderen für tierärztliche Anwendungen |
US6916658B2 (en) * | 2001-07-27 | 2005-07-12 | Beckman Coulter, Inc. | Method for measurement of immature granulocytes |
US6410330B1 (en) | 2001-07-27 | 2002-06-25 | Coulter International Corp. | Method for measurement of nucleated red blood cells |
WO2003012429A1 (en) | 2001-07-27 | 2003-02-13 | Coulter International Corp. | Method for measurement of nucleated red blood cells |
US6573102B2 (en) * | 2001-07-27 | 2003-06-03 | Coulter International Corp. | Lytic reagent composition for determination of nucleated blood cells |
US6890756B2 (en) * | 2002-04-05 | 2005-05-10 | Streck Laboratories, Inc. | Method of using cyanide-free lyse solution to emulate a cyanide-containing lyse solution in the measurement of hemoglobin |
AU2005297497B2 (en) * | 2004-10-20 | 2010-09-23 | Koninklijke Philips Electronics N.V. | Lysing reagent for simultaneous enumeration of different types of blood cells in a blood sample |
US7235404B2 (en) * | 2005-05-04 | 2007-06-26 | Beckman Coulter, Inc. | Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement |
CN101078720B (zh) * | 2006-05-22 | 2010-12-01 | 深圳迈瑞生物医疗电子股份有限公司 | 一种改进的用于对白细胞进行分类的试剂及方法 |
CN101078721B (zh) * | 2006-05-23 | 2010-12-22 | 深圳迈瑞生物医疗电子股份有限公司 | 对白细胞进行分类的试剂及方法 |
CN101548181B (zh) * | 2007-04-27 | 2012-11-28 | 爱科来株式会社 | 利用毛细管电泳法的血红蛋白分析方法及该方法中使用的添加剂 |
CN101349644B (zh) * | 2007-07-20 | 2012-06-27 | 深圳迈瑞生物医疗电子股份有限公司 | 一种白细胞分类试剂和其使用方法 |
WO2009057293A1 (ja) * | 2007-10-30 | 2009-05-07 | Panasonic Corporation | ヘモグロビン及びヘモグロビン誘導体の測定方法、測定キット |
CN105440725A (zh) * | 2008-01-04 | 2016-03-30 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类荧光染料,组合物及在生物样品染色中的用途 |
CN101602762B (zh) * | 2008-06-10 | 2013-10-16 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类化合物、其制备方法及应用 |
CN101726579B (zh) * | 2008-10-17 | 2014-06-18 | 深圳迈瑞生物医疗电子股份有限公司 | 血液检测试剂和方法 |
US8192995B2 (en) | 2008-11-13 | 2012-06-05 | Beckman Coulter, Inc. | Method of correction of particle interference to hemoglobin measurement |
CN101750274B (zh) * | 2008-12-17 | 2014-06-25 | 深圳迈瑞生物医疗电子股份有限公司 | 白细胞分类计数试剂、试剂盒以及白细胞分类计数的方法 |
CN101988082B (zh) * | 2009-07-31 | 2015-04-08 | 深圳迈瑞生物医疗电子股份有限公司 | 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法 |
KR101413280B1 (ko) | 2012-05-31 | 2014-06-30 | 성낙도 | 잠재혈흔 현출제와 현출방법 |
CN104634953A (zh) * | 2015-02-28 | 2015-05-20 | 韩冰 | 一种环保无毒型溶血剂 |
KR102646392B1 (ko) | 2015-03-31 | 2024-03-11 | 에이껜 가가꾸 가부시끼가이샤 | 헴 단백질의 보존액 및 헴 단백질의 안정화 방법 |
CN107907691B (zh) * | 2017-11-15 | 2020-10-30 | 南通伊仕生物技术股份有限公司 | 一种肌红蛋白检测试剂盒及其使用方法 |
CN107957495B (zh) * | 2017-11-17 | 2020-10-09 | 南通伊仕生物技术股份有限公司 | 一种ck-mb检测试剂盒及其使用方法 |
WO2019222620A1 (en) | 2018-05-17 | 2019-11-21 | Beckman Coulter, Inc. | Green concentrated reagent for hematology systems |
CN110133080B (zh) * | 2019-04-25 | 2021-11-02 | 广州万孚生物技术股份有限公司 | 血红蛋白电化学检测组合物以及血红蛋白电化学传感器 |
CN110470587B (zh) * | 2019-08-12 | 2021-11-09 | 江苏美诚生物科技有限公司 | 一种五分类血细胞分析仪用嗜碱性粒细胞计数套装 |
CN110702892A (zh) * | 2019-09-09 | 2020-01-17 | 金华市鑫科医疗器械有限公司 | 一种血细胞分析仪用血红蛋白浓度测定专用试剂 |
US11191460B1 (en) | 2020-07-15 | 2021-12-07 | Shani Biotechnologies LLC | Device and method for measuring blood components |
Family Cites Families (18)
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US2660009A (en) * | 1952-01-05 | 1953-11-24 | Lyon Inc | Abrading wheel |
US4185964A (en) * | 1977-02-08 | 1980-01-29 | Central Laboratories of Associated Maryland Pathologists, Ltd. | Lysing reagent |
US4213876A (en) * | 1978-08-22 | 1980-07-22 | Coulter Electronics, Inc. | Multi-purpose blood diluent for use in electronic blood analysis instrumentation |
DE2839433A1 (de) * | 1978-09-11 | 1980-03-20 | Merck Patent Gmbh | Waessrige lipid-standardloesung und verfahren zu ihrer herstellung |
EP0010577B1 (de) * | 1978-11-01 | 1981-11-11 | Contraves Ag | Verfahren zur Verminderung der Störung einer photometrischen Messung durch Lichtstreuung in einer zu messenden Suspension und Reagenz zur Durchführung des Verfahrens |
US4286963A (en) * | 1979-11-23 | 1981-09-01 | Coulter Electronics, Inc. | Differential lymphoid-myeloid determination of leukocytes in whole blood |
US4244837A (en) * | 1979-12-03 | 1981-01-13 | Coulter Electronics, Inc. | Multi-purpose blood diluent for use in electronic blood analysis instrumentation |
US4528274A (en) * | 1982-07-06 | 1985-07-09 | Coulter Electronics, Inc. | Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes |
US4485175A (en) * | 1983-01-03 | 1984-11-27 | Coulter Electronics, Inc. | Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes |
JPS6035270A (ja) * | 1983-08-05 | 1985-02-23 | Wako Pure Chem Ind Ltd | ヘモグロビンの分解防止方法 |
US4637986A (en) * | 1983-08-22 | 1987-01-20 | Ortho Diagnostic Systems, Inc. | Flow cytometry lysing reagent with leukoprotective agent for producing a 3-part WBC count |
JPS6073356A (ja) * | 1983-09-29 | 1985-04-25 | Toa Medical Electronics Co Ltd | 血液分析用試薬 |
CA1255197A (en) * | 1984-09-24 | 1989-06-06 | Joseph L. Orlik | Leukocyte differentiation composition and method |
US4871677A (en) * | 1985-02-25 | 1989-10-03 | Hemotec, Inc. | Method of collecting and analyzing a sample of blood when monitoring heparin therapy |
US4745071A (en) * | 1985-09-05 | 1988-05-17 | Sequoia-Turner Corporation | Method for the volumetric differentiation of blood cells types |
JPS63108000A (ja) * | 1986-05-15 | 1988-05-12 | Green Cross Corp:The | 第8因子の精製方法 |
US4853338A (en) * | 1987-05-20 | 1989-08-01 | Technicon Instruments Corporation | Cyanide-free hemoglobin reagent |
JP2619900B2 (ja) * | 1988-01-27 | 1997-06-11 | 東亜医用電子株式会社 | 血液中の白血球およびヘモグロビンの測定用試薬および方法 |
-
1990
- 1990-10-10 US US07/596,205 patent/US5242832A/en not_active Expired - Lifetime
- 1990-10-12 CA CA002027451A patent/CA2027451C/en not_active Expired - Fee Related
- 1990-10-23 DE DE69015999T patent/DE69015999T2/de not_active Expired - Fee Related
- 1990-10-23 EP EP90120293A patent/EP0444241B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5242832A (en) | 1993-09-07 |
CA2027451A1 (en) | 1991-09-02 |
CA2027451C (en) | 2002-07-23 |
EP0444241A1 (de) | 1991-09-04 |
DE69015999D1 (de) | 1995-02-23 |
EP0444241B1 (de) | 1995-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |