DE69012663T2 - Verfahren zur Herstellung von alpha-Asparaginsäure-L-phenylalaninmethylester. - Google Patents

Verfahren zur Herstellung von alpha-Asparaginsäure-L-phenylalaninmethylester.

Info

Publication number
DE69012663T2
DE69012663T2 DE69012663T DE69012663T DE69012663T2 DE 69012663 T2 DE69012663 T2 DE 69012663T2 DE 69012663 T DE69012663 T DE 69012663T DE 69012663 T DE69012663 T DE 69012663T DE 69012663 T2 DE69012663 T2 DE 69012663T2
Authority
DE
Germany
Prior art keywords
alpha
preparation
methyl ester
aspartic acid
phenylalanine methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69012663T
Other languages
English (en)
Other versions
DE69012663D1 (de
Inventor
Masanobu Ajioka
Takeshi Oura
Chojiro Higuchi
Toshio Katoh
Akihiro Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Application granted granted Critical
Publication of DE69012663D1 publication Critical patent/DE69012663D1/de
Publication of DE69012663T2 publication Critical patent/DE69012663T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • C07K5/06121Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69012663T 1989-06-14 1990-06-14 Verfahren zur Herstellung von alpha-Asparaginsäure-L-phenylalaninmethylester. Expired - Fee Related DE69012663T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1149515A JP2728936B2 (ja) 1989-06-14 1989-06-14 α―L―アスパルチル―L―スェニルアラニンメチルエステルの製造方法

Publications (2)

Publication Number Publication Date
DE69012663D1 DE69012663D1 (de) 1994-10-27
DE69012663T2 true DE69012663T2 (de) 1995-04-13

Family

ID=15476825

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69012663T Expired - Fee Related DE69012663T2 (de) 1989-06-14 1990-06-14 Verfahren zur Herstellung von alpha-Asparaginsäure-L-phenylalaninmethylester.

Country Status (7)

Country Link
US (1) US5206413A (de)
EP (1) EP0402926B1 (de)
JP (1) JP2728936B2 (de)
KR (1) KR920006561B1 (de)
BR (1) BR9002799A (de)
CA (1) CA2018896A1 (de)
DE (1) DE69012663T2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010002083A (ko) * 1999-06-11 2001-01-05 고두모 알파-엘-아스파틸-엘-페닐알라닌 메틸에스테르의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5235660B2 (de) * 1972-05-25 1977-09-10
JPS6049199B2 (ja) * 1979-04-10 1985-10-31 東ソー株式会社 α−L−アスパルチル−L−フエニルアラニン低級アルキルエステルの精製法
GB2140805B (en) * 1983-05-31 1986-08-13 Erba Farmitalia Isolation of aspartame

Also Published As

Publication number Publication date
US5206413A (en) 1993-04-27
KR920006561B1 (ko) 1992-08-08
EP0402926A2 (de) 1990-12-19
KR910000787A (ko) 1991-01-30
JP2728936B2 (ja) 1998-03-18
BR9002799A (pt) 1991-08-20
JPH0317097A (ja) 1991-01-25
EP0402926B1 (de) 1994-09-21
DE69012663D1 (de) 1994-10-27
EP0402926A3 (de) 1991-10-30
CA2018896A1 (en) 1990-12-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee