DE69011046T2 - Pyridinderivate, Verfahren zur Herstellung und pharmazeutische Zusammensetzungen. - Google Patents

Pyridinderivate, Verfahren zur Herstellung und pharmazeutische Zusammensetzungen.

Info

Publication number
DE69011046T2
DE69011046T2 DE69011046T DE69011046T DE69011046T2 DE 69011046 T2 DE69011046 T2 DE 69011046T2 DE 69011046 T DE69011046 T DE 69011046T DE 69011046 T DE69011046 T DE 69011046T DE 69011046 T2 DE69011046 T2 DE 69011046T2
Authority
DE
Germany
Prior art keywords
pyridine
cyanimino
formula
compound
nitroimino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69011046T
Other languages
German (de)
English (en)
Other versions
DE69011046D1 (de
Inventor
Gyoergy Dr Domany
Elemer Ezer
Gyoergy Dr Hajos
Judit Dr Matuz
Marta Renyet
Katalin Dr Saghy
Istvan Dr Schon
Laszlo Dr Szporny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of DE69011046D1 publication Critical patent/DE69011046D1/de
Application granted granted Critical
Publication of DE69011046T2 publication Critical patent/DE69011046T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached
    • C07D213/77—Hydrazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69011046T 1989-11-07 1990-11-07 Pyridinderivate, Verfahren zur Herstellung und pharmazeutische Zusammensetzungen. Expired - Fee Related DE69011046T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU895807A HU207047B (en) 1989-11-07 1989-11-07 Process for producing new pyridine derivatives and pharmaceutical copositions comprising same

Publications (2)

Publication Number Publication Date
DE69011046D1 DE69011046D1 (de) 1994-09-01
DE69011046T2 true DE69011046T2 (de) 1994-11-24

Family

ID=10970765

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69011046T Expired - Fee Related DE69011046T2 (de) 1989-11-07 1990-11-07 Pyridinderivate, Verfahren zur Herstellung und pharmazeutische Zusammensetzungen.

Country Status (20)

Country Link
US (1) US5155123A (enExample)
EP (1) EP0427526B1 (enExample)
JP (1) JPH03169862A (enExample)
KR (1) KR910009663A (enExample)
CN (1) CN1052305A (enExample)
AR (1) AR248394A1 (enExample)
AT (1) ATE109137T1 (enExample)
AU (1) AU631261B2 (enExample)
CA (1) CA2029222A1 (enExample)
DE (1) DE69011046T2 (enExample)
DK (1) DK0427526T3 (enExample)
ES (1) ES2057441T3 (enExample)
FI (1) FI905493A7 (enExample)
HU (1) HU207047B (enExample)
IL (1) IL96252A (enExample)
IN (1) IN171700B (enExample)
NO (1) NO177263C (enExample)
NZ (1) NZ235984A (enExample)
PH (1) PH27440A (enExample)
ZA (1) ZA908889B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1035115E (pt) 1999-02-24 2005-01-31 Hoffmann La Roche Derivados de 4-fenilpiridina e a sua utilizacao como antagonistas do receptor nk-1
US7288658B2 (en) 2003-07-15 2007-10-30 Hoffmann-La Roche Inc. Process for preparation of pyridine derivatives
DE602006011485D1 (de) 2005-09-23 2010-02-11 Hoffmann La Roche Neue dosierformulierung
EP2789237A1 (en) * 2010-08-31 2014-10-15 Meiji Seika Pharma Co., Ltd. Pest control agent
EP2749555B1 (en) * 2011-08-26 2018-11-14 Meiji Seika Pharma Co., Ltd. Method for producing pest controlling agent
CN112585137A (zh) 2018-08-07 2021-03-30 先正达农作物保护股份公司 杀有害生物活性的二环杂芳香族化合物
AR117291A1 (es) 2018-12-14 2021-07-28 Syngenta Crop Protection Ag Compuestos heterocíclicos de cianamida con actividad pesticida
WO2020169526A1 (en) 2019-02-18 2020-08-27 Syngenta Crop Protection Ag Pesticidally-active cyanamide heterocyclic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1201119A (en) * 1978-09-18 1986-02-25 Mcneilab, Inc. Diaza-cyclic derivatives of guanidine
HU188852B (en) * 1983-03-16 1986-05-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for producing thiazolidine derivatives active against gastric ulcer and intestinal ulcer
JPH07121909B2 (ja) * 1986-09-10 1995-12-25 日本バイエルアグロケム株式会社 新規複素環式化合物及び殺虫剤

Also Published As

Publication number Publication date
KR910009663A (ko) 1991-06-28
ZA908889B (en) 1991-10-30
DE69011046D1 (de) 1994-09-01
PH27440A (en) 1993-07-02
NO177263C (no) 1995-08-16
IL96252A0 (en) 1991-08-16
FI905493A7 (fi) 1991-05-08
IN171700B (enExample) 1992-12-12
NO904822L (no) 1991-05-08
AU6582390A (en) 1991-05-23
ES2057441T3 (es) 1994-10-16
CA2029222A1 (en) 1991-05-08
ATE109137T1 (de) 1994-08-15
DK0427526T3 (da) 1994-08-29
IL96252A (en) 1994-12-29
EP0427526A1 (en) 1991-05-15
AU631261B2 (en) 1992-11-19
EP0427526B1 (en) 1994-07-27
NZ235984A (en) 1992-08-26
HU895807D0 (en) 1990-01-28
HU207047B (en) 1993-03-01
NO904822D0 (no) 1990-11-06
JPH03169862A (ja) 1991-07-23
NO177263B (no) 1995-05-08
FI905493A0 (fi) 1990-11-06
US5155123A (en) 1992-10-13
HUT55758A (en) 1991-06-28
AR248394A1 (es) 1995-08-18
CN1052305A (zh) 1991-06-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee