DE69005165T2 - Arzneimittel, das einen pharmazeutisch geeigneten Träger sowie die Verbindung der Struktur (7-alpha, 17-alpha)-17-Hydroxy-7-methyl-19-nor-17-pregn-5(10)-ene-20-yne-3-one enthält. - Google Patents

Arzneimittel, das einen pharmazeutisch geeigneten Träger sowie die Verbindung der Struktur (7-alpha, 17-alpha)-17-Hydroxy-7-methyl-19-nor-17-pregn-5(10)-ene-20-yne-3-one enthält.

Info

Publication number
DE69005165T2
DE69005165T2 DE90200574T DE69005165T DE69005165T2 DE 69005165 T2 DE69005165 T2 DE 69005165T2 DE 90200574 T DE90200574 T DE 90200574T DE 69005165 T DE69005165 T DE 69005165T DE 69005165 T2 DE69005165 T2 DE 69005165T2
Authority
DE
Germany
Prior art keywords
alpha
compound
pregn
hydroxy
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE90200574T
Other languages
English (en)
Other versions
DE69005165D1 (de
Inventor
G A J M T Sas
Doornum E M Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19854317&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69005165(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo NV filed Critical Akzo NV
Application granted granted Critical
Publication of DE69005165D1 publication Critical patent/DE69005165D1/de
Publication of DE69005165T2 publication Critical patent/DE69005165T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE90200574T 1989-03-18 1990-03-12 Arzneimittel, das einen pharmazeutisch geeigneten Träger sowie die Verbindung der Struktur (7-alpha, 17-alpha)-17-Hydroxy-7-methyl-19-nor-17-pregn-5(10)-ene-20-yne-3-one enthält. Expired - Lifetime DE69005165T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8900673 1989-03-18

Publications (2)

Publication Number Publication Date
DE69005165D1 DE69005165D1 (de) 1994-01-27
DE69005165T2 true DE69005165T2 (de) 1994-05-05

Family

ID=19854317

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90200574T Expired - Lifetime DE69005165T2 (de) 1989-03-18 1990-03-12 Arzneimittel, das einen pharmazeutisch geeigneten Träger sowie die Verbindung der Struktur (7-alpha, 17-alpha)-17-Hydroxy-7-methyl-19-nor-17-pregn-5(10)-ene-20-yne-3-one enthält.

Country Status (17)

Country Link
US (1) US5037817A (de)
EP (1) EP0389035B1 (de)
JP (2) JP3139709B2 (de)
KR (1) KR0183401B1 (de)
AT (1) ATE98490T1 (de)
AU (1) AU625083B2 (de)
CA (1) CA2011452C (de)
DE (1) DE69005165T2 (de)
DK (1) DK0389035T3 (de)
ES (1) ES2062292T3 (de)
FI (1) FI94865C (de)
HK (1) HK1002019A1 (de)
IE (1) IE63051B1 (de)
MX (1) MX9203787A (de)
NZ (1) NZ232946A (de)
PT (1) PT93488B (de)
ZA (1) ZA901674B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA941464B (en) * 1993-03-05 1994-09-27 Akzo Nv Use of pregnane derivative
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
IL123984A (en) 1997-04-22 2004-09-27 Akzo Nobel Nv Pharmacological dosage units containing tibolone and carrier pharmacy are acceptable
ES2197677T3 (es) * 1998-10-16 2004-01-01 Akzo Nobel N.V. Composiciones de alta pureza que comprenden (7alfa-17alfa)-17-hidroxi-7-metil-19-nor-17-pregn-5(10)-en-20-in-3-ona.
US7045513B1 (en) 1999-03-18 2006-05-16 Genelabs Technologies, Inc. DHEA composition and method
CN100544726C (zh) * 1999-03-18 2009-09-30 基因实验室技术公司 Dhea制剂及方法
TWI265167B (en) 1999-11-29 2006-11-01 Akzo Nobel Nv 3-methylene steroid derivatives
US20040229854A1 (en) * 2000-11-28 2004-11-18 Pieter Haan De Immediate release dosage form for HRT
MXPA04003588A (es) * 2001-10-18 2005-04-11 Norton Healthcare Ltd Nuevas formulaciones de tibolona.
GB0125061D0 (en) * 2001-10-18 2001-12-12 Norton Healthcare Ltd Pharmaceutical composition
RU2004125594A (ru) * 2002-01-22 2005-03-10 Акцо Нобель Н.В. (NL) Применение тиболона при лечение симптомов, связанных с введением лекарств, препятствующих синтезу эндогенного эстрогена
GB0304927D0 (en) 2003-03-04 2003-04-09 Resolution Chemicals Ltd Process for the production of tibolone
CN1324041C (zh) * 2003-04-01 2007-07-04 上海迪赛诺医药科技开发有限公司 替勃龙晶型i的制备方法
AU2004203420B8 (en) * 2003-05-23 2008-02-21 N.V. Organon Immediate-release pharmaceutical dosage form comprising polymorphous tibolone
WO2006125453A1 (en) * 2005-05-23 2006-11-30 Newchem S.P.A. Process for the preparation of pure crystalline tibolone
EP1821571A1 (de) * 2006-02-15 2007-08-22 Oticon A/S Schleifenantenne für In-dem-Ohr-Hörereinrichtung
ITMI20130120A1 (it) * 2013-01-25 2014-07-26 Ind Chimica Srl Processo per la preparazione in forma cristallina di tibolone, (7alfa,17alfa)-17-idrossi-7-metil-19-norpregn-5(10)-en-20-in-3-one
EP3452019B1 (de) 2016-05-04 2021-06-23 Novalon S.A. Verwendung von zuckeralkoholen in tibolonzusammensetzungen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE665514A (de) * 1964-06-16
US4933168A (en) * 1975-05-27 1990-06-12 Syntex Pharmaceuticals International Limited Stable, crystalline flunisolide
US4273710A (en) * 1979-05-21 1981-06-16 Syntex Corporation Process for preparing flunisolide
US4391755A (en) * 1982-01-18 1983-07-05 E. R. Squibb & Sons, Inc. Steroid monohydrates, formulations containing same and method
US4447426A (en) * 1982-01-18 1984-05-08 E. R. Squibb & Sons, Inc. Steroid monohydrates, formulations containing same and method
US4701450A (en) * 1984-03-21 1987-10-20 Akzo N.V. Steroids for use as immunomodulators

Also Published As

Publication number Publication date
PT93488A (pt) 1990-11-07
IE63051B1 (en) 1995-03-22
ATE98490T1 (de) 1994-01-15
DK0389035T3 (da) 1994-02-14
US5037817A (en) 1991-08-06
ES2062292T3 (es) 1994-12-16
EP0389035B1 (de) 1993-12-15
IE900709L (en) 1990-09-18
KR900013950A (ko) 1990-10-22
PT93488B (pt) 1996-02-29
NZ232946A (en) 1991-08-27
FI94865C (fi) 1995-11-10
HK1002019A1 (en) 1998-07-24
AU625083B2 (en) 1992-07-02
JP2001139473A (ja) 2001-05-22
DE69005165D1 (de) 1994-01-27
JP3139709B2 (ja) 2001-03-05
CA2011452A1 (en) 1990-09-18
FI901328A0 (fi) 1990-03-16
KR0183401B1 (ko) 1999-05-01
AU5139490A (en) 1990-09-20
MX9203787A (es) 1992-07-01
CA2011452C (en) 1999-05-25
ZA901674B (en) 1990-12-28
JPH0347195A (ja) 1991-02-28
FI94865B (fi) 1995-07-31
EP0389035A1 (de) 1990-09-26

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: AKZO NOBEL N.V., ARNHEIM/ARNHEM, NL

8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: N.V. ORGANON, OSS, NL