DE68928492D1 - Elektrochemilumineszente reaktion unter verwendung eines von einem amin abgeleiteten reduktionsmittels - Google Patents

Elektrochemilumineszente reaktion unter verwendung eines von einem amin abgeleiteten reduktionsmittels

Info

Publication number
DE68928492D1
DE68928492D1 DE68928492T DE68928492T DE68928492D1 DE 68928492 D1 DE68928492 D1 DE 68928492D1 DE 68928492 T DE68928492 T DE 68928492T DE 68928492 T DE68928492 T DE 68928492T DE 68928492 D1 DE68928492 D1 DE 68928492D1
Authority
DE
Germany
Prior art keywords
amine
exposure
moiety
reducing agent
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68928492T
Other languages
English (en)
Other versions
DE68928492T2 (de
Inventor
Jonathan Leland
Michael Powell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioveris Corp
Original Assignee
IGEN Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IGEN Inc filed Critical IGEN Inc
Application granted granted Critical
Publication of DE68928492D1 publication Critical patent/DE68928492D1/de
Publication of DE68928492T2 publication Critical patent/DE68928492T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Control Of El Displays (AREA)
  • Luminescent Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE68928492T 1988-11-03 1989-10-31 Elektrochemilumineszente reaktion unter verwendung eines von einem amin abgeleiteten reduktionsmittels Expired - Lifetime DE68928492T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26691488A 1988-11-03 1988-11-03
PCT/US1989/004859 WO1990005296A1 (en) 1988-11-03 1989-10-31 Electrochemiluminescent reaction utilizing amine-derived reductant

Publications (2)

Publication Number Publication Date
DE68928492D1 true DE68928492D1 (de) 1998-01-22
DE68928492T2 DE68928492T2 (de) 1998-08-20

Family

ID=23016522

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68928492T Expired - Lifetime DE68928492T2 (de) 1988-11-03 1989-10-31 Elektrochemilumineszente reaktion unter verwendung eines von einem amin abgeleiteten reduktionsmittels

Country Status (8)

Country Link
EP (1) EP0441894B1 (de)
JP (1) JPH076913B2 (de)
AT (1) ATE161096T1 (de)
AU (2) AU641374B2 (de)
CA (1) CA2002099C (de)
DE (1) DE68928492T2 (de)
HK (1) HK1006353A1 (de)
WO (1) WO1990005296A1 (de)

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US6702986B1 (en) * 1988-04-29 2004-03-09 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
RU2116647C1 (ru) * 1993-05-03 1998-07-27 Берингер Маннхайм ГмбХ Способы измерения электрохемилюминесцентных явлений и определения анализируемого вещества и реактив
US5541113A (en) * 1993-09-22 1996-07-30 Beckman Instruments, Inc. Method for detecting an analyte using an electrochemical luminescent transition metal label
US6319670B1 (en) 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
EP0791821A4 (de) * 1995-09-12 1999-10-27 Eisai Co Ltd Verfahren und vorrichtung zum nachweis von elektrochemilumineszenz
US6146838A (en) * 1997-03-18 2000-11-14 Igen International, Inc. Detecting water-borne parasites using electrochemiluminescence
DE19811582A1 (de) * 1998-03-17 1999-09-23 Roche Diagnostics Gmbh Stabilisierung und Verstärkung von Elektrochemilumineszenz-Signalen
DE19828441A1 (de) 1998-06-25 1999-12-30 Roche Diagnostics Gmbh Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren
US6136268A (en) * 1999-08-17 2000-10-24 Orion Diagnostica Method for luminescence measurements
USRE46351E1 (en) 2001-05-10 2017-03-28 Battelle Energy Alliance, Llc Antibody profiling sensitivity through increased reporter antibody layering
US6989276B2 (en) 2001-05-10 2006-01-24 Battelle Energy Alliance, Llc Rapid classification of biological components
US7695919B2 (en) 2001-05-10 2010-04-13 Battelle Energy Alliance, Llc Antibody profiling sensitivity through increased reporter antibody layering
USRE44031E1 (en) 2001-05-10 2013-02-26 Battelle Energy Alliance, Llc Antibody profiling sensitivity through increased reporter antibody layering
CA2932756C (en) * 2001-09-10 2020-07-07 Meso Scale Technologies, Llc Assay buffer, compositions containing the same, and methods of using the same
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US7310544B2 (en) 2004-07-13 2007-12-18 Dexcom, Inc. Methods and systems for inserting a transcutaneous analyte sensor
US20070045902A1 (en) 2004-07-13 2007-03-01 Brauker James H Analyte sensor
US7749772B1 (en) 2006-06-29 2010-07-06 Varian, Inc. Antibody and immunoassays for determining the presence of Δ9-Tetrahydrocannabinol
RU2009102155A (ru) * 2006-06-30 2010-08-10 Апплера Корпорейшн (Us) Способы анализирования связывающих взаимодействий
US8351674B2 (en) 2007-05-31 2013-01-08 Battelle Energy Alliance, Llc Image portion identification methods, image parsing methods, image parsing systems, and articles of manufacture
US8969009B2 (en) 2009-09-17 2015-03-03 Vicki S. Thompson Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual
US9410965B2 (en) 2009-09-17 2016-08-09 Battelle Energy Alliance, Llc Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual
EP3338094B1 (de) 2015-08-20 2019-05-08 H. Hoffnabb-La Roche Ag Partikelbasierter immunoassay unter verwendung eines pegylierten analytspezifischen bindemittels
JP7065781B2 (ja) 2016-03-07 2022-05-12 エフ．ホフマン－ラ ロシュ アーゲー 抗ｐ５３抗体の検出
JP7039481B2 (ja) 2016-03-11 2022-03-22 エフ．ホフマン－ラ ロシュ アーゲー 電気化学発光検出における分枝鎖アミン
JP7068323B2 (ja) 2017-02-02 2022-05-16 エフ．ホフマン－ラ ロシュ アーゲー 少なくとも２種のペグ化された分析物特異的結合剤を使用する免疫アッセイ
CN111936522B (zh) 2018-04-18 2024-07-02 豪夫迈·罗氏有限公司 新型抗胸苷激酶抗体
CN112639475A (zh) 2018-08-31 2021-04-09 豪夫迈·罗氏有限公司 Dlbcl的预后指数中的胸苷激酶(tk-1)
EP3906412A1 (de) 2019-01-03 2021-11-10 Meso Scale Technologies, LLC Zusammensetzungen und verfahren zur durchführung von testmessungen
CN114144676A (zh) 2019-07-22 2022-03-04 豪夫迈·罗氏有限公司 S100a6作为血液生物标志物用于子宫内膜异位症的非侵入性诊断
WO2021013783A1 (en) 2019-07-22 2021-01-28 F. Hoffmann-La Roche Ag S100a12 as blood biomarker for the non-invasive diagnosis of endometriosis
KR20220016210A (ko) 2019-07-22 2022-02-08 에프. 호프만-라 로슈 아게 자궁내막증의 비-침습적 진단용 혈액 생물표지자로써 s100a9
JP7421631B2 (ja) 2019-07-22 2024-01-24 エフ． ホフマン－ラ ロシュ アーゲー 子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのｓ１００ａ８
WO2021013781A1 (en) 2019-07-22 2021-01-28 F. Hoffmann-La Roche Ag Substance p as blood biomarker for the non-invasive diagnosis of endometriosis
WO2021019732A1 (ja) 2019-07-31 2021-02-04 株式会社日立ハイテク 生体分子分析方法および生体分子分析装置
CN114728984A (zh) 2019-11-15 2022-07-08 豪夫迈·罗氏有限公司 用于患者样品中质谱测量的β-内酰胺类抗生素的衍生化
JP2023547505A (ja) 2020-11-02 2023-11-10 エフ． ホフマン－ラ ロシュ アーゲー ＳＡＲＳ－ＣｏＶ－２ヌクレオカプシド抗体
WO2022207628A1 (en) 2021-03-30 2022-10-06 F. Hoffmann-La Roche Ag Scf as blood biomarker for the non-invasive diagnosis of endometriosis
EP4314838A1 (de) 2021-04-01 2024-02-07 F. Hoffmann-La Roche AG Psp94 als blutbiomarker zur nichtinvasiven diagnose von endometriose
WO2022243210A1 (en) 2021-05-17 2022-11-24 F. Hoffmann-La Roche Ag sFRP4 AS BLOOD BIOMARKER FOR THE NON-INVASIVE DIAGNOSIS OF ADENOMYOSIS
WO2023072904A1 (en) 2021-10-26 2023-05-04 F. Hoffmann-La Roche Ag Monoclonal antibodies specific for sars-cov-2 rbd
WO2023131594A1 (en) 2022-01-05 2023-07-13 F. Hoffmann-La Roche Ag Derivatization of compounds in patient samples for therapeutic drug monitoring (tdm)
WO2023247752A1 (en) 2022-06-23 2023-12-28 F. Hoffmann-La Roche Ag Method for diagnosing endometriosis and for classifying the stage of endometriosis
WO2024017985A1 (en) 2022-07-22 2024-01-25 F. Hoffmann-La Roche Ag Fibroblast growth factor binding protein 1 (fgfbp1) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome
WO2024017982A1 (en) 2022-07-22 2024-01-25 F. Hoffmann-La Roche Ag Leukotriene a4 hydrolase (lta4h) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome
WO2024017983A1 (en) 2022-07-22 2024-01-25 F. Hoffmann-La Roche Ag Meteorin-like protein (metrnl) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293310A (en) * 1980-03-14 1981-10-06 University Of Pittsburgh Photoelectrochemical immunoassay
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US4853327A (en) * 1985-07-10 1989-08-01 Molecular Diagnostics, Inc. Enhanced phthalazinedione chemiluminescence
DE3752345T2 (de) * 1986-04-30 2002-08-22 Igen International, Inc. Elektrolumineszente Verbindungen und Zwischenprodukte zur Herstellung

Also Published As

Publication number Publication date
DE68928492T2 (de) 1998-08-20
AU4657289A (en) 1990-05-28
AU641374B2 (en) 1993-09-23
JPH04502964A (ja) 1992-05-28
EP0441894A1 (de) 1991-08-21
AU667594B2 (en) 1996-03-28
CA2002099A1 (en) 1990-05-03
ATE161096T1 (de) 1997-12-15
AU5269793A (en) 1994-03-10
EP0441894A4 (en) 1992-09-16
WO1990005296A1 (en) 1990-05-17
CA2002099C (en) 2001-01-09
HK1006353A1 (en) 1999-02-19
JPH076913B2 (ja) 1995-01-30
EP0441894B1 (de) 1997-12-10

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: IGEN INTERNATIONAL,INC.(N.D.GES.D.STAATES DELAWARE

8327 Change in the person/name/address of the patent owner

Owner name: BIOVERIS CORP.(N.D.GES.D.STAATES DELAWARE), GAITHE