ES8202011A1 - Un procedimiento para la preparacion de derivados de campto-tecina - Google Patents

Un procedimiento para la preparacion de derivados de campto-tecina

Info

Publication number
ES8202011A1
ES8202011A1 ES499986A ES499986A ES8202011A1 ES 8202011 A1 ES8202011 A1 ES 8202011A1 ES 499986 A ES499986 A ES 499986A ES 499986 A ES499986 A ES 499986A ES 8202011 A1 ES8202011 A1 ES 8202011A1
Authority
ES
Spain
Prior art keywords
group
translation
derivatives
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES499986A
Other languages
English (en)
Other versions
ES499986A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yakult Honsha Co Ltd
Original Assignee
Yakult Honsha Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8641179A external-priority patent/JPS5612392A/ja
Priority claimed from JP8641279A external-priority patent/JPS5612393A/ja
Priority claimed from JP8641379A external-priority patent/JPS5612394A/ja
Priority claimed from JP8641079A external-priority patent/JPS5612391A/ja
Application filed by Yakult Honsha Co Ltd filed Critical Yakult Honsha Co Ltd
Publication of ES499986A0 publication Critical patent/ES499986A0/es
Publication of ES8202011A1 publication Critical patent/ES8202011A1/es
Expired legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE CAMPTOETECINA DE FORMULA GENERAL (I), DONDE X'''''' REPRESENTA UN GRUPO ALQUILO, ARALQUILO O -COOR4, DONDE R4 ES H O UN GRUPO ALQUILO INFERIOR, ASI COMO SUS SALES DE METALES ALCALINOS SOLUBLES EN AGUA. CONSISTE EN SOMETER A LA CAMPTOTECINA A UNA REACCION RADICALICA CON UN COMPUESTO ORGANICO DE FORMULA (II), DONDE Q REPRESENTA UN GRUPO -CH2OH, -COOH, -CHO O -COX'''', Y X'''' REPRESENTA UN GRUPO ALQUILO O ARALQUILO, CON LA AYUDA DE UN ACIDO SULFURICO Y UN PEROXIDO EN MEDIO ACUOSO, EN PRESENCIA DE UN ION METALICO DE TRANSICION, Y OPCIONALMENTE OXIDAR EL DERIVADO DE 7-X''''-CAMPTOTECINA RESULTANTE, DONDE X'''' REPRESENTA UN GRUPO ALQUILO, A UNA 7-X''''''-CAMPTOTECINA, DONDE X'''''' REPRESENTA UN GRUPO CARBOXI, Y DESPUES, ESTERIFICAR EL GRUPO CARBOXI.
ES499986A 1979-07-10 1981-03-02 Un procedimiento para la preparacion de derivados de campto-tecina Expired ES8202011A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP8641179A JPS5612392A (en) 1979-07-10 1979-07-10 Novel camptothecin derivative and its preparation
JP8641279A JPS5612393A (en) 1979-07-10 1979-07-10 Novel camptothecin derivative
JP8641379A JPS5612394A (en) 1979-07-10 1979-07-10 Novel camptothecin derivative
JP8641079A JPS5612391A (en) 1979-07-10 1979-07-10 Novel camptothecin derivative and its preparaion

Publications (2)

Publication Number Publication Date
ES499986A0 ES499986A0 (es) 1982-01-01
ES8202011A1 true ES8202011A1 (es) 1982-01-01

Family

ID=27467257

Family Applications (3)

Application Number Title Priority Date Filing Date
ES493287A Granted ES493287A0 (es) 1979-07-10 1980-07-10 Un procedimiento para la preparacion de derivados de campto tecina.
ES499986A Expired ES8202011A1 (es) 1979-07-10 1981-03-02 Un procedimiento para la preparacion de derivados de campto-tecina
ES499987A Expired ES8202012A1 (es) 1979-07-10 1981-03-02 Un procedimiento para la preparacion de derivados de campto-tecina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES493287A Granted ES493287A0 (es) 1979-07-10 1980-07-10 Un procedimiento para la preparacion de derivados de campto tecina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES499987A Expired ES8202012A1 (es) 1979-07-10 1981-03-02 Un procedimiento para la preparacion de derivados de campto-tecina

Country Status (1)

Country Link
ES (3) ES493287A0 (es)

Also Published As

Publication number Publication date
ES499987A0 (es) 1982-01-01
ES8202012A1 (es) 1982-01-01
ES499986A0 (es) 1982-01-01
ES8105735A1 (es) 1981-06-16
ES493287A0 (es) 1981-06-16

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